{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T23:43:09Z","timestamp":1792107789566,"version":"4.4.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Dental Journal"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.identj.2026.109643","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T21:33:25Z","timestamp":1779917605000},"page":"109643","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Neurosensory Disturbances Related to the Inferior Alveolar Nerve Amongst Patients With Mandibular Medication-Related Osteonecrosis of the Jaw (MRONJ): A Clinical and Radiological Overview"],"prefix":"10.1016","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-4262-7811","authenticated-orcid":false,"given":"Yui Yin","family":"Ko","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6047-3705","authenticated-orcid":false,"given":"Wei-fa","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6670-6570","authenticated-orcid":false,"given":"Yiu Yan","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.identj.2026.109643_bib0001","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.joms.2022.02.008","article-title":"American Association of Oral and Maxillofacial Surgeons' Position Paper on Medication-Related Osteonecrosis of the Jaws-2022 Update","volume":"80","author":"Ruggiero","year":"2022","journal-title":"J Oral Maxillofac Surg"},{"issue":"4","key":"10.1016\/j.identj.2026.109643_bib0002","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1210\/er.2001-2002","article-title":"Meta-analyses of therapies for postmenopausal osteoporosis. II. Meta-analysis of alendronate for the treatment of postmenopausal women","volume":"23","author":"Cranney","year":"2002","journal-title":"Endocr Rev"},{"issue":"17","key":"10.1016\/j.identj.2026.109643_bib0003","doi-asserted-by":"crossref","first-page":"3719","DOI":"10.1200\/JCO.2002.06.037","article-title":"American Society of Clinical Oncology clinical practice guidelines: the role of bisphosphonates in multiple myeloma","volume":"20","author":"Berenson","year":"2002","journal-title":"J Clin Oncol"},{"issue":"19","key":"10.1016\/j.identj.2026.109643_bib0004","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1093\/jnci\/94.19.1458","article-title":"A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma","volume":"94","author":"Saad","year":"2002","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"10.1016\/j.identj.2026.109643_bib0005","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1080\/13696998.2019.1651122","article-title":"Cost-effectiveness of denosumab for the prevention of skeletal-related events in patients with solid tumors and bone metastases in the United States","volume":"23","author":"Stopeck","year":"2020","journal-title":"J Med Econ"},{"issue":"2","key":"10.1016\/j.identj.2026.109643_bib0006","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1007\/s00774-019-01052-6","article-title":"Zoledronic acid and skeletal-related events in patients with bone metastatic cancer or multiple myeloma","volume":"38","author":"Jeon","year":"2020","journal-title":"J Bone Miner Metab"},{"key":"10.1016\/j.identj.2026.109643_bib0007","unstructured":"Surgeons AAoOaM. Medication-Related Osteonecrosis of the Jaw \u20132022 Update. Rosemont, Illinois; 2022."},{"issue":"4","key":"10.1016\/j.identj.2026.109643_bib0008","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/sj.bdj.2010.157","article-title":"Numb chin syndrome: a case series and discussion","volume":"208","author":"Divya","year":"2010","journal-title":"Br Dent J"},{"issue":"1","key":"10.1016\/j.identj.2026.109643_bib0009","doi-asserted-by":"crossref","first-page":"80","DOI":"10.11607\/jop.994","article-title":"Numb chin syndrome: a rare and often overlooked symptom","volume":"28","author":"Assaf","year":"2014","journal-title":"J Oral Facial Pain Headache"},{"issue":"7","key":"10.1016\/j.identj.2026.109643_bib0010","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/sj.bdj.2010.292","article-title":"Numb chin syndrome: an ominous clinical sign","volume":"208","author":"Ryba","year":"2010","journal-title":"Br Dent J"},{"issue":"5","key":"10.1016\/j.identj.2026.109643_bib0011","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/j.joms.2007.12.046","article-title":"Mental neuropathy as a manifestation associated with malignant processes: its significance in relation to patient survival","volume":"66","author":"Sanchis","year":"2008","journal-title":"J Oral Maxillofac Surg"},{"issue":"1","key":"10.1016\/j.identj.2026.109643_bib0012","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S1040-8428(00)00050-0","article-title":"Mental neuropathy: report of five cases and review of the literature","volume":"34","author":"Laurencet","year":"2000","journal-title":"Crit Rev Oncol Hematol"},{"issue":"1","key":"10.1016\/j.identj.2026.109643_bib0013","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/0030-4220(90)90268-W","article-title":"Mental nerve neuropathy in systemic cancer. Report of three cases","volume":"69","author":"Penarrocha Diago","year":"1990","journal-title":"Oral Surg Oral Med Oral Pathol"},{"issue":"4","key":"10.1016\/j.identj.2026.109643_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.identj.2025.100862","article-title":"Numb chin sign and the role of radiology","volume":"75","author":"MacDonald","year":"2025","journal-title":"Int Dent J"},{"issue":"3","key":"10.1016\/j.identj.2026.109643_bib0015","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.joms.2008.09.028","article-title":"The role of inferior alveolar nerve involvement in bisphosphonate-related osteonecrosis of the jaw","volume":"67","author":"Otto","year":"2009","journal-title":"J Oral Maxillofac Surg"},{"issue":"5","key":"10.1016\/j.identj.2026.109643_bib0016","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.jormas.2018.04.006","article-title":"Numb chin syndrome: a reflection of malignancy or a harbinger of MRONJ? A multicenter experience","volume":"119","author":"Fortunato","year":"2018","journal-title":"J Stomatol Oral Maxillofac Surg"},{"issue":"11","key":"10.1016\/j.identj.2026.109643_bib0017","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.jfma.2017.07.002","article-title":"Numb chin with mandibular pain or masticatory weakness as indicator for systemic malignancy - a case series study","volume":"116","author":"Lu","year":"2017","journal-title":"J Formos Med Assoc"},{"issue":"3","key":"10.1016\/j.identj.2026.109643_bib0018","first-page":"e282","article-title":"Changes in dimension of neurovascular canals in the mandible and maxilla: a radiographic finding in patients diagnosed with MRONJ","volume":"23","author":"Goller-Bulut","year":"2018","journal-title":"Med Oral Patol Oral Cir Bucal"},{"issue":"2","key":"10.1016\/j.identj.2026.109643_bib0019","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jcm.2016.02.012","article-title":"A guideline of selecting and reporting intraclass correlation coefficients for reliability research","volume":"15","author":"Koo","year":"2016","journal-title":"J Chiropr Med"},{"issue":"3","key":"10.1016\/j.identj.2026.109643_bib0020","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.jds.2017.12.003","article-title":"Clinical analysis of medication related osteonecrosis of the jaws: a growing severe complication in China","volume":"13","author":"Wang","year":"2018","journal-title":"J Dent Sci"},{"issue":"1","key":"10.1016\/j.identj.2026.109643_bib0021","doi-asserted-by":"crossref","DOI":"10.1259\/dmfr.20180128","article-title":"Medication related osteonecrosis of the jaw in osteoporotic vs oncologic patients-quantifying radiographic appearance and relationship to clinical findings","volume":"48","author":"Walton","year":"2019","journal-title":"Dentomaxillofac Radiol"},{"issue":"10","key":"10.1016\/j.identj.2026.109643_bib0022","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s00784-024-05911-z","article-title":"Medication-related osteonecrosis of the jaw: a retrospective single center study of recurrence-related factors after surgical treatment","volume":"28","author":"Ruan","year":"2024","journal-title":"Clin Oral Investig"},{"issue":"4","key":"10.1016\/j.identj.2026.109643_bib0023","doi-asserted-by":"crossref","first-page":"287","DOI":"10.5624\/isd.2019.49.4.287","article-title":"Clinical and panoramic radiographic features of osteomyelitis of the jaw: a comparison between antiresorptive medication-related and medication-unrelated conditions","volume":"49","author":"Shin","year":"2019","journal-title":"Imaging Sci Dent"},{"issue":"6","key":"10.1016\/j.identj.2026.109643_bib0024","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.3174\/ajnr.A0518","article-title":"Imaging findings of bisphosphonate-associated osteonecrosis of the jaws","volume":"28","author":"Phal","year":"2007","journal-title":"AJNR Am J Neuroradiol"},{"issue":"2","key":"10.1016\/j.identj.2026.109643_bib0025","doi-asserted-by":"crossref","first-page":"e69","DOI":"10.1016\/j.oooo.2016.04.007","article-title":"Imaging features of medicine-related osteonecrosis of the jaws: comparison between panoramic radiography and computed tomography","volume":"122","author":"Guo","year":"2016","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"issue":"1","key":"10.1016\/j.identj.2026.109643_bib0026","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-96910-x","article-title":"The usefulness of different imaging modalities in mandibular osteonecrosis and osteomyelitis diagnosis","volume":"15","author":"Kawasaki","year":"2025","journal-title":"Sci Rep"},{"key":"10.1016\/j.identj.2026.109643_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejrad.2023.110916","article-title":"Radiologic findings of osteonecrosis, osteoradionecrosis, osteomyelitis and jaw metastatic disease with cone beam CT","volume":"165","author":"Yfanti","year":"2023","journal-title":"Eur J Radiol"},{"issue":"2","key":"10.1016\/j.identj.2026.109643_bib0028","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/odi.13534","article-title":"Osteomyelitis, osteoradionecrosis, or medication-related osteonecrosis of the jaws? Can CBCT enhance radiographic diagnosis?","volume":"27","author":"Gaeta-Araujo","year":"2021","journal-title":"Oral Dis"},{"issue":"6","key":"10.1016\/j.identj.2026.109643_bib0029","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1067\/moe.2000.110418","article-title":"Paresthesia of the mental nerve induced by periapical infection: a case report","volume":"90","author":"Di Lenarda","year":"2000","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"7","key":"10.1016\/j.identj.2026.109643_bib0030","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S0099-2399(97)80303-2","article-title":"Infection-related mental and inferior alveolar nerve paresthesia: literature review and presentation of two cases","volume":"23","author":"Morse","year":"1997","journal-title":"J Endod"},{"issue":"7","key":"10.1016\/j.identj.2026.109643_bib0031","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.joen.2023.05.004","article-title":"Resolution of apical periodontitis-induced mental nerve paresthesia through nonsurgical endodontic retreatment: a case report","volume":"49","author":"Buchanan","year":"2023","journal-title":"J Endod"},{"issue":"5","key":"10.1016\/j.identj.2026.109643_bib0032","doi-asserted-by":"crossref","first-page":"e28","DOI":"10.1016\/j.tripleo.2008.01.023","article-title":"Paresthesia of the mental nerve stem from periapical infection of mandibular canine tooth: a case report","volume":"105","author":"Ozkan","year":"2008","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"11","key":"10.1016\/j.identj.2026.109643_bib0033","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1053\/joms.2000.16621","article-title":"Factors affecting neurosensory disturbance after mandibular bilateral sagittal split osteotomy","volume":"58","author":"Ylikontiola","year":"2000","journal-title":"J Oral Maxillofac Surg"},{"issue":"9","key":"10.1016\/j.identj.2026.109643_bib0034","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.ijom.2011.04.002","article-title":"The role of intraoperative positioning of the inferior alveolar nerve on postoperative paresthesia after bilateral sagittal split osteotomy of the mandible: prospective clinical study","volume":"40","author":"Hanzelka","year":"2011","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"4","key":"10.1016\/j.identj.2026.109643_bib0035","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.jcms.2020.02.017","article-title":"Medication-related osteonecrosis of the jaw (MRONJ) stage III: Conservative and conservative surgical approaches versus an aggressive surgical intervention: a systematic review","volume":"48","author":"Vanpoecke","year":"2020","journal-title":"J Craniomaxillofac Surg"},{"issue":"1","key":"10.1016\/j.identj.2026.109643_bib0036","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1054\/ijom.2001.0157","article-title":"Risk factors of nerve injury during mandibular sagittal split osteotomy","volume":"31","author":"Teerijoki-Oksa","year":"2002","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"5","key":"10.1016\/j.identj.2026.109643_bib0037","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.bjoms.2020.08.106","article-title":"Histological evaluation of inferior alveolar nerve injury after osteotomy of mandibular buccal cortex using piezoelectric versus conventional rotary devices: a split-mouth randomised study in rabbits","volume":"59","author":"Zandi","year":"2021","journal-title":"Br J Oral Maxillofac Surg"},{"issue":"3","key":"10.1016\/j.identj.2026.109643_bib0038","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1007\/s12663-012-0335-0","article-title":"Inferior alveolar nerve deficits and recovery following surgical removal of impacted mandibular third molars","volume":"11","author":"Bhat","year":"2012","journal-title":"J Maxillofac Oral Surg"},{"issue":"5","key":"10.1016\/j.identj.2026.109643_bib0039","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.jcms.2022.02.008","article-title":"Inferior alveolar nerve preservation during resection and reconstruction of the mandible for benign tumors as a factor improving patient's quality of life","volume":"50","author":"Tereshchuk","year":"2022","journal-title":"J Craniomaxillofac Surg"},{"issue":"8","key":"10.1016\/j.identj.2026.109643_bib0040","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0072891","article-title":"Trigeminal neurosensory deficit and patient reported outcome measures: the effect on life satisfaction and depression symptoms","volume":"8","author":"Leung","year":"2013","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.identj.2026.109643_bib0041","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0077391","article-title":"Trigeminal neurosensory deficit and patient reported outcome measures: the effect on quality of life","volume":"8","author":"Leung","year":"2013","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.identj.2026.109643_bib0042","doi-asserted-by":"crossref","first-page":"225","DOI":"10.2485\/jhtb.28.225","article-title":"The use of a piezoelectric device for the removal of a sequestrum involving the inferior alveolar nerve in patients with medication-related osteonecrosis of the jaws: evaluation of clinical outcomes with comparison to a conventional device","volume":"28","author":"Yoshimura","year":"2019","journal-title":"Journal of Hard Tissue Biology"},{"issue":"7","key":"10.1016\/j.identj.2026.109643_bib0043","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.bjoms.2015.04.013","article-title":"Preservation of the inferior alveolar neurovascular bundle in the osteotomy of benign lesions of the mandible using a digital template","volume":"53","author":"Huang","year":"2015","journal-title":"Br J Oral Maxillofac Surg"}],"container-title":["International Dental Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020653926002364?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020653926002364?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:38:26Z","timestamp":1790681906000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020653926002364"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":43,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S0020653926002364"],"URL":"https:\/\/doi.org\/10.1016\/j.identj.2026.109643","relation":{},"ISSN":["0020-6539"],"issn-type":[{"value":"0020-6539","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neurosensory Disturbances Related to the Inferior Alveolar Nerve Amongst Patients With Mandibular Medication-Related Osteonecrosis of the Jaw (MRONJ): A Clinical and Radiological Overview","name":"articletitle","label":"Article Title"},{"value":"International Dental Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.identj.2026.109643","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of FDI World Dental Federation.","name":"copyright","label":"Copyright"}],"article-number":"109643"}}