{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:11:31Z","timestamp":1786990291658,"version":"build-2736575974"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,3,25]],"date-time":"2019-03-25T00:00:00Z","timestamp":1553472000000},"content-version":"vor","delay-in-days":83,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007099","name":"San Diego State University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007099","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infectious Disease Modelling"],"published-print":{"date-parts":[[2019]]},"DOI":"10.1016\/j.idm.2019.03.001","type":"journal-article","created":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T03:07:35Z","timestamp":1553742455000},"page":"28-43","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Modeling transmission dynamics of lyme disease: Multiple vectors, seasonality, and vector mobility"],"prefix":"10.1016","volume":"4","author":[{"given":"Aileen","family":"Nguyen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Mahaffy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveen K.","family":"Vaidya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.idm.2019.03.001_bib1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1128\/jcm.22.1.36-38.1985","article-title":"Identification of endemic foci of lyme disease: Isolation of Borrelia burgdorferi from feral rodents and ticks (Dermacentor variabilis)","volume":"22","author":"Anderson","year":"1985","journal-title":"Journal of Clinical Microbiology"},{"key":"10.1016\/j.idm.2019.03.001_bib2","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1007\/s11538-006-9166-9","article-title":"Approximation of the basic reproduction number R0 for vector-borne diseases with a periodic vector population","volume":"69","author":"Baca\u00ebr","year":"2007","journal-title":"Bulletin of Mathematical Biology"},{"key":"10.1016\/j.idm.2019.03.001_bib3","doi-asserted-by":"crossref","first-page":"18","DOI":"10.2307\/2424681","article-title":"Population dynamics of the white-footed mouse in floodplain and upland forests","volume":"97","author":"Batzli","year":"1977","journal-title":"The American Midland Naturalist"},{"key":"10.1016\/j.idm.2019.03.001_bib4","first-page":"651","article-title":"Prevalence of the lyme disease spirochete in populations of white-tailed deer and white-footed mice","volume":"57","author":"Bosler","year":"1984","journal-title":"Yale Journal of Biology & Medicine"},{"key":"10.1016\/j.idm.2019.03.001_bib5","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1289\/ehp.6052","article-title":"A\u00a0climate-based model predicts the spatial distribution of the lyme disease vector Ixodes scapularis in the United States","volume":"111","author":"Brownstein","year":"2003","journal-title":"Environmental Health Perspectives"},{"key":"10.1016\/j.idm.2019.03.001_bib6","doi-asserted-by":"crossref","first-page":"S1442","DOI":"10.1093\/clinids\/11.Supplement_6.S1442","article-title":"Pathophysiology of the lyme disease spriochete, Borrelia burgdorferi, in ixodid ticks","volume":"11","author":"Burgdorfer","year":"1989","journal-title":"Reviews of Infectious Diseases"},{"key":"10.1016\/j.idm.2019.03.001_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13071-016-1894-6","article-title":"The impact of temperature and precipitation on blacklegged tick activity and Lyme disease incidence in endemic and emerging regions","volume":"9","author":"Burtis","year":"2016","journal-title":"Parasites & Vectors"},{"key":"10.1016\/j.idm.2019.03.001_bib8","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1086\/341518","article-title":"Stage-structured infection transmission and a spatial epidemic: A model for lyme disease","volume":"160","author":"Caraco","year":"2002","journal-title":"The American Naturalist"},{"key":"10.1016\/j.idm.2019.03.001_bib9","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1093\/jmedent\/37.3.357","article-title":"Estimating population size and drag sampling efficiency for the blacklegged tick (Acari:ixodidae)","volume":"37","author":"Daniels","year":"2000","journal-title":"Journal of Medical Entomology"},{"key":"10.1016\/j.idm.2019.03.001_bib10","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1098\/rsif.2009.0386","article-title":"The construction of next-generation matrices for compartmental epidemic models","volume":"7","author":"Diekmann","year":"2010","journal-title":"Journal of The Royal Society Interface"},{"key":"10.1016\/j.idm.2019.03.001_bib11","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0025-5564(02)00108-6","article-title":"Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission","volume":"180","author":"van den Driessche","year":"2002","journal-title":"Mathematical Biosciences"},{"key":"10.1016\/j.idm.2019.03.001_bib12","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/BF01219108","article-title":"A\u00a0comparison of methods for sampling the deer tick, Ixodes dammini, in a lyme disease endemic area","volume":"14","author":"Falco","year":"1992","journal-title":"Experimental & Applied Acarology"},{"key":"10.1016\/j.idm.2019.03.001_bib13","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1016\/j.bulm.2004.03.007","article-title":"Seasonal population dynamics of ticks, and its influence on infection transmission: A semi-discrete approach","volume":"66","author":"Ghosh","year":"2004","journal-title":"Bulletin of Mathematical Biology"},{"key":"10.1016\/j.idm.2019.03.001_bib14","doi-asserted-by":"crossref","first-page":"538","DOI":"10.4269\/ajtmh.1994.51.538","article-title":"Predicting Ixodes scapularis abundance on white-tailed deer using geographic information systems","volume":"51","author":"Glass","year":"1994","journal-title":"The American Journal of Tropical Medicine and Hygiene"},{"key":"10.1016\/j.idm.2019.03.001_bib15","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1089\/153036601316977732","article-title":"Spatiotemperal variation in a lyme disease host and vector: Black-legged ticks on white-footed mice","volume":"1","author":"Goodwin","year":"2001","journal-title":"Vector Borne and Zoonotic Diseases"},{"key":"10.1016\/j.idm.2019.03.001_bib16","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.theriogenology.2017.02.010","article-title":"Reproductive characteristics of female white-tailed deer (Odocoileus virginianus) in the Midwestern USA","volume":"94","author":"Green","year":"2017","journal-title":"Theriogenology"},{"key":"10.1016\/j.idm.2019.03.001_bib17","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1086\/587530","article-title":"The basic reproduction number for complex disease systems: Defining R0 for tick-borne infections","volume":"171","author":"Hartemink","year":"2008","journal-title":"The American Naturalist"},{"key":"10.1016\/j.idm.2019.03.001_bib18","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s10903-008-9187-6","article-title":"Behavioral and attitudes survey about lyme disease among a Brazilian population in the endemic area of Martha's vineyard, Massachusetts","volume":"12","author":"Heller","year":"2010","journal-title":"Journal of Immigrant and Minority Health"},{"key":"10.1016\/j.idm.2019.03.001_bib19","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1093\/jmedent\/44.5.752","article-title":"Effects of reduced deer density on the abundance of Ixodes scapularis (Acari: Ixodidae) and lyme disease incidence in a Northern New Jersey endemic area","volume":"44","author":"Jordan","year":"2007","journal-title":"Journal of Medical Entomology"},{"key":"10.1016\/j.idm.2019.03.001_bib20","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1111\/j.1461-0248.2006.00885.x","article-title":"Effects of species diversity on disease risk","volume":"9","author":"Keesing","year":"2006","journal-title":"Ecology Letters"},{"key":"10.1016\/j.idm.2019.03.001_bib21","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1001\/jama.2013.278331","article-title":"CDC estimates 300000 us cases of lyme disease annually","volume":"310","author":"Kuehn","year":"2013","journal-title":"Journal of the American Medical Association"},{"key":"10.1016\/j.idm.2019.03.001_bib22","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.3201\/eid2108.141878","article-title":"Geographic distribution and expansion of human lyme disease, United States","volume":"21","author":"Kugeler","year":"2015","journal-title":"Emerging Infectious Diseases"},{"issue":"27","key":"10.1016\/j.idm.2019.03.001_bib23","doi-asserted-by":"crossref","first-page":"10942","DOI":"10.1073\/pnas.1204536109","article-title":"Deer, predators, and the emergence of lyme disease","volume":"109","author":"Levi","year":"2012","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"10.1016\/j.idm.2019.03.001_bib24","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1093\/jmedent\/32.2.143","article-title":"Survival and development of Ixodes scapularis (Acari:ixodidae) under various climatic conditions in Ontario, Canada","volume":"32","author":"Lindsay","year":"1995","journal-title":"Journal of Medical Entomology"},{"key":"10.1016\/j.idm.2019.03.001_bib25","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1007\/s11538-009-9477-8","article-title":"A\u00a0tuberculosis model with seasonality","volume":"72","author":"Liu","year":"2010","journal-title":"Bulletin of Mathematical Biology"},{"key":"10.1016\/j.idm.2019.03.001_bib26","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1073\/pnas.0233733100","article-title":"The ecology of infectious disease: Effects of host diversity and community composition on lyme disease risk","volume":"100","author":"LoGiudice","year":"2003","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"10.1016\/j.idm.2019.03.001_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1742-4682-11-50","article-title":"Impact of biodiversity and seasonality on Lyme-pathogen transmission","volume":"11","author":"Lou","year":"2014","journal-title":"Theoretical Biology and Medical Modelling"},{"key":"10.1016\/j.idm.2019.03.001_bib28","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1603\/0022-2585-41.5.842","article-title":"A\u00a0dispersal model for the range expansion of blacklegged tick (Acardi:Ixodidae)","volume":"41","author":"Madhav","year":"2004","journal-title":"Journal of Medical Entomology"},{"key":"10.1016\/j.idm.2019.03.001_bib29","first-page":"19","article-title":"Geographic distribution of white-tailed deer with ticks and antibodies to Borrelia burgdorferi in Connecticut","volume":"66","author":"Magnarelli","year":"1993","journal-title":"Yale Journal of Biology & Medicine"},{"key":"10.1016\/j.idm.2019.03.001_bib30","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1128\/jcm.33.3.541-544.1995","article-title":"Borrelia burgdorferi in an urban environment: White-tailed deer with infected ticks and antibodies","volume":"33","author":"Magnarelli","year":"1995","journal-title":"Journal of Clinical Microbiology"},{"key":"10.1016\/j.idm.2019.03.001_bib31","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1017\/S0031182006001417","article-title":"Vector seasonality, host infection dynamics and fitness of pathogens transmitted by the tick Ixodes scapularis","volume":"134","author":"Ogden","year":"2007","journal-title":"Parasitology"},{"key":"10.1016\/j.idm.2019.03.001_bib32","doi-asserted-by":"crossref","first-page":"266","DOI":"10.2307\/1382727","article-title":"Causes and consequences of tick (Ixodes scapularis) burdens on white-footed mice (Peromyscus leucopus)","volume":"77","author":"Ostfeld","year":"1996","journal-title":"Journal of Mammalogy"},{"key":"10.1016\/j.idm.2019.03.001_bib33","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1093\/jmedent\/32.6.765","article-title":"General framework for comparative quantitative studies on transmission of tick-borne diseases using lyme borreliosis in europe as an example","volume":"32","author":"Randolph","year":"1995","journal-title":"Journal of Medical Entomology"},{"key":"10.1016\/j.idm.2019.03.001_bib34","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1017\/S0031182098003643","article-title":"Incidence from coincidence: Patterns of tick infestations on rodents facilitate transmission of tick-borne encephalitis virus","volume":"118","author":"Randolph","year":"1999","journal-title":"Parasitology"},{"key":"10.1016\/j.idm.2019.03.001_bib35","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3121\/cmr.1.1.5","article-title":"Birds, migration, and emerging zoonoses: West nile virus, lyme disease, influenza a and enteropathogens","volume":"1","author":"Reed","year":"2003","journal-title":"Clinical Medicine and Research"},{"key":"10.1016\/j.idm.2019.03.001_bib36","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1890\/08-2106.1","article-title":"Community ecology and disease risk: Lizards, squirrels, and the lyme disease spirochete in California, USA","volume":"91","author":"Salkeld","year":"2010","journal-title":"Ecology"},{"key":"10.1016\/j.idm.2019.03.001_bib37","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1128\/JCM.38.1.382-388.2000","article-title":"Temporal changes in outer surface proteins A and C of the lyme disease-associated spriochete, Borrelia burgdorferi, during the chain of infection in ticks and mice","volume":"38","author":"Schwan","year":"2000","journal-title":"Journal of Clinical Microbiology"},{"key":"10.1016\/j.idm.2019.03.001_bib38","doi-asserted-by":"crossref","first-page":"420","DOI":"10.2307\/3799028","article-title":"Seasonal activity patterns of white-tailed deer in eastern south Dakota","volume":"34","author":"Sparrowe","year":"1970","journal-title":"Journal of Wildlife Management"},{"key":"10.1016\/j.idm.2019.03.001_bib39","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1137\/140966642","article-title":"Avian influenza dynamics under periodic environmental conditions","volume":"75","author":"Vaidya","year":"2015","journal-title":"SIAM Journal on Applied Mathematics"},{"key":"10.1016\/j.idm.2019.03.001_bib40","doi-asserted-by":"crossref","first-page":"881","DOI":"10.2307\/3799320","article-title":"Reproductive patterns of white-tailed deer related to nutritional plane","volume":"33","author":"Verme","year":"1969","journal-title":"Journal of Wildlife Management"},{"key":"10.1016\/j.idm.2019.03.001_bib41","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1007\/s10884-008-9111-8","article-title":"Threshold dynamics for compartmental epidemic models in periodic environments","volume":"20","author":"Wang","year":"2008","journal-title":"Journal of Dynamics and Differential Equations"},{"key":"10.1016\/j.idm.2019.03.001_bib42","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1137\/16M1087916","article-title":"Dynamics of a time-delayed lyme disease model with seasonality","volume":"16","author":"Wang","year":"2017","journal-title":"SIAM Journal on Applied Dynamical Systems"},{"key":"10.1016\/j.idm.2019.03.001_bib43","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1128\/aem.55.8.1921-1924.1989","article-title":"Lyme disease and migrating birds in the saint croix river valley","volume":"55","author":"Weisbrod","year":"1989","journal-title":"Applied and Environmental Microbiology"}],"container-title":["Infectious Disease Modelling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468042718300538?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468042718300538?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T04:05:29Z","timestamp":1762833929000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2468042718300538"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":43,"alternative-id":["S2468042718300538"],"URL":"https:\/\/doi.org\/10.1016\/j.idm.2019.03.001","relation":{},"ISSN":["2468-0427"],"issn-type":[{"value":"2468-0427","type":"print"}],"subject":[],"published":{"date-parts":[[2019]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Modeling transmission dynamics of lyme disease: Multiple vectors, seasonality, and vector mobility","name":"articletitle","label":"Article Title"},{"value":"Infectious Disease Modelling","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.idm.2019.03.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.","name":"copyright","label":"Copyright"}]}}