{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T15:22:48Z","timestamp":1779895368432,"version":"3.53.1"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T00:00:00Z","timestamp":1602115200000},"content-version":"vor","delay-in-days":281,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infectious Disease Modelling"],"published-print":{"date-parts":[[2020]]},"DOI":"10.1016\/j.idm.2020.10.004","type":"journal-article","created":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T01:31:10Z","timestamp":1602811870000},"page":"871-888","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Estimates for Lyme borreliosis infections based on models using sentinel canine and human seroprevalence data"],"prefix":"10.1016","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0678-1819","authenticated-orcid":false,"given":"Michael J.","family":"Cook","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6101-0139","authenticated-orcid":false,"given":"Basant K.","family":"Puri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.idm.2020.10.004_bib1","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1086\/514970","article-title":"Disparity between serological reactivity to Borrelia burgdorferi and evidence of past disease in a high-risk group","volume":"27","author":"Arteaga","year":"2007","journal-title":"Clinical Infectious Diseases"},{"issue":"4","key":"10.1016\/j.idm.2020.10.004_bib2","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1111\/vcp.12213","article-title":"Comparison of different diagnostic assays for the detection of Borrelia burgdorferi-specific antibodies in dogs","volume":"43","author":"Barth","year":"2014","journal-title":"Veterinary Clinical Pathology\/American Society for Veterinary Clinical Pathology"},{"issue":"4","key":"10.1016\/j.idm.2020.10.004_bib3","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.vetpar.2009.03.028","article-title":"Emerging arthropod-borne diseases of companion animals in Europe","volume":"163","author":"Beugnet","year":"2009","journal-title":"Veterinary Parasitology"},{"key":"10.1016\/j.idm.2020.10.004_bib4","series-title":"Lyme and tick-borne infections patient survey","author":"Bloor","year":"2014"},{"issue":"3","key":"10.1016\/j.idm.2020.10.004_bib5","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1021\/ie50063a027","article-title":"Experiments with small animals and carbon monoxide","volume":"6","author":"Burrell","year":"1914","journal-title":"Journal of Industrial and Engineering Chemistry"},{"issue":"12","key":"10.1016\/j.idm.2020.10.004_bib6","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1111\/ene.12477","article-title":"A\u00a0study on the association between infectious burden and Alzheimer\u2019s disease","volume":"22","author":"Bu","year":"2015","journal-title":"European Journal of Neurology"},{"issue":"6","key":"10.1016\/j.idm.2020.10.004_bib7","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1093\/ije\/dyi129","article-title":"Post-lyme borreliosis syndrome: A meta-analysis of reported symptoms","volume":"34","author":"Cairns","year":"2005","journal-title":"International Journal of Epidemiology"},{"key":"10.1016\/j.idm.2020.10.004_bib8","series-title":"CDC provides estimate of Americans diagnosed with Lyme disease each year","year":"2013"},{"key":"10.1016\/j.idm.2020.10.004_bib9","series-title":"Lyme hastaligi \u201cIklim degisiminin ilk pandemisi\u201d","author":"\u00c7etin","year":"2018"},{"issue":"1","key":"10.1016\/j.idm.2020.10.004_bib10","first-page":"141","article-title":"Lyme borreliosis and multiple sclerosis: Any connection? A seroepidemic study","volume":"7","author":"Chmielewska-Badora","year":"2000","journal-title":"Annals of Agricultural and Environmental Medicine"},{"key":"10.1016\/j.idm.2020.10.004_bib11","series-title":"Parasite prevalence Maps: Tick borne disease agents: Lyme disease: Dogs","author":"Companion Animal Parasite Council","year":"2019"},{"key":"10.1016\/j.idm.2020.10.004_bib12","doi-asserted-by":"crossref","first-page":"427","DOI":"10.2147\/IJGM.S122313","article-title":"Commercial test kits for the detection of Lyme borreliosis: A meta-analysis of test accuracy","volume":"9","author":"Cook","year":"2016","journal-title":"International Journal of General Medicine"},{"key":"10.1016\/j.idm.2020.10.004_bib13","doi-asserted-by":"crossref","first-page":"113","DOI":"10.2147\/IJGM.S131909","article-title":"Application of Bayesian decision-making to laboratory testing for Lyme disease and comparison with testing for HIV","volume":"10","author":"Cook","year":"2017","journal-title":"International Journal of General Medicine"},{"issue":"352","key":"10.1016\/j.idm.2020.10.004_bib14","first-page":"1","article-title":"Estimation of cumulative number of post- treatment Lyme disease cases in the US , 2016 and 2020","volume":"19","author":"Delong","year":"2019","journal-title":"BMC Public Health"},{"issue":"2","key":"10.1016\/j.idm.2020.10.004_bib15","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1089\/vbz.2005.5.101","article-title":"The dog as a sentinel for human infection: Prevalence of Borrelia burgdorferi C6 antibodies in dogs from southeastern and mid-atlantic states","volume":"5","author":"Duncan","year":"2005","journal-title":"Vector Borne and Zoonotic Diseases"},{"issue":"6","key":"10.1016\/j.idm.2020.10.004_bib16","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1093\/infdis\/158.6.1410","article-title":"Greater risk of Borrelia burgdorferi infection in dogs than in people","volume":"158","author":"Eng","year":"1988","journal-title":"The Journal of Infectious Diseases"},{"issue":"2","key":"10.1016\/j.idm.2020.10.004_bib17","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1023\/A:1007404620701","article-title":"Longterm survey (7 years) in a population at risk for Lyme borreliosis: What happens to the seropositive individuals?","volume":"14","author":"Fahrer","year":"1998","journal-title":"European Journal of Epidemiology"},{"issue":"9","key":"10.1016\/j.idm.2020.10.004_bib18","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.2105\/AJPH.83.9.1305","article-title":"The distribution of canine exposure to Borrelia burgdorferi in a Lyme-Disease endemic area","volume":"83","author":"Falco","year":"1993","journal-title":"American Journal of Public Health"},{"issue":"5","key":"10.1016\/j.idm.2020.10.004_bib19","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s00103-013-1919-7","article-title":"Public health pests. Arthropods and rodents as causative disease agents as well as reservoirs and vectors of pathogens","volume":"57","author":"Faulde","year":"2014","journal-title":"Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz"},{"key":"10.1016\/j.idm.2020.10.004_bib20","first-page":"844","volume":"Vol. 39","author":"Goossens","year":"2001"},{"issue":"1","key":"10.1016\/j.idm.2020.10.004_bib21","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0923-2508(97)83621-2","article-title":"Arguments against the involvement of Borrelia burgdorferi sensu lato in Alzheimer\u2019s disease","volume":"149","author":"Gutacker","year":"1998","journal-title":"Research in Microbiology"},{"issue":"8636","key":"10.1016\/j.idm.2020.10.004_bib22","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/S0140-6736(89)91377-9","article-title":"Lyme disease: Prevalence and clinical importance of Borrelia burgdorferi specific IgG in forestry workers","volume":"1","author":"Guy","year":"1989","journal-title":"Lancet"},{"issue":"19","key":"10.1016\/j.idm.2020.10.004_bib23","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1212\/WNL.0b013e31828726f5","article-title":"Alzheimer disease in the United States (2010-2050) estimated using the 2010 census","volume":"80","author":"Hebert","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.idm.2020.10.004_bib24","series-title":"Clinical infectious Diseases","article-title":"Lyme disease testing by large commercial laboratories in the United States","author":"Hinckley","year":"2014"},{"issue":"11","key":"10.1016\/j.idm.2020.10.004_bib25","first-page":"374","article-title":"Serologic studies of the occurrence of Borrelia burgdorferi in domestic animals in Berlin (West)","volume":"103","author":"K\u00e4sbohrer","year":"1990","journal-title":"Berliner und M\u00fcnchener Tier\u00e4rztliche Wochenschrift"},{"issue":"3","key":"10.1016\/j.idm.2020.10.004_bib26","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0163-4453(91)92936-Y","article-title":"Lyme borreliosis in Dutch forestry workers","volume":"23","author":"Kuiper","year":"1991","journal-title":"Journal of Infection"},{"issue":"6","key":"10.1016\/j.idm.2020.10.004_bib27","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/BF01967434","article-title":"One year follow-up study to assess the prevalence and incidence of Lyme borreliosis among Dutch forestry workers","volume":"12","author":"Kuiper","year":"1993","journal-title":"European Journal of Clinical Microbiology & Infectious Diseases"},{"issue":"11","key":"10.1016\/j.idm.2020.10.004_bib28","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.2105\/AJPH.81.11.1448","article-title":"Dogs as sentinels for Lyme disease in Massachusetts","volume":"81","author":"Lindenmayer","year":"1991","journal-title":"American Journal of Public Health"},{"key":"10.1016\/j.idm.2020.10.004_bib29","article-title":"Lyme borreliosis in Europe\u00a0: Influences of climate and climate change , epidemiology, ecology and adaptation measures","volume":"Vol. EU\/04\/5046","author":"Lindgren","year":"2006"},{"issue":"16","key":"10.1016\/j.idm.2020.10.004_bib30","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1001\/jama.1986.03380160053011","article-title":"Borrelia in the brains of patients dying with dementia","volume":"256","author":"MacDonald","year":"1986","journal-title":"Journal of the American Medical Association"},{"issue":"3","key":"10.1016\/j.idm.2020.10.004_bib31","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.mehy.2006.02.035","article-title":"Plaques of Alzheimer\u2019s disease originate from cysts of Borrelia burgdorferi, the Lyme disease spirochete","volume":"67","author":"MacDonald","year":"2006","journal-title":"Medical Hypotheses"},{"issue":"4","key":"10.1016\/j.idm.2020.10.004_bib32","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1023\/A:1007535313763","article-title":"Low risk of Lyme borreliosis in a protected area on the Tyrrhenian coast, in central Italy","volume":"15","author":"Mannelli","year":"1999","journal-title":"European Journal of Epidemiology"},{"issue":"Suppl","key":"10.1016\/j.idm.2020.10.004_bib33","first-page":"345","article-title":"Borrelia burgdorferi: Risk factor in alzheimer\u2019s DiseasePoster session 2 , monday 12 september","volume":"18","author":"Marquard","year":"2011","journal-title":"European Journal of Neurology"},{"key":"10.1016\/j.idm.2020.10.004_bib34","first-page":"1999","article-title":"Lack of evidence of Borrelia involvement in alzheimer \u2019 s disease","volume":"182","author":"Marques","year":"2000","journal-title":"Journal of Infectious Diseases"},{"issue":"7","key":"10.1016\/j.idm.2020.10.004_bib35","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1097\/00001756-199905140-00018","article-title":"Alzheimer\u2019s disease may not be a spirochetosis","volume":"10","author":"McLaughlin","year":"1999","journal-title":"NeuroReport"},{"issue":"9","key":"10.1016\/j.idm.2020.10.004_bib36","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.3201\/1709.110210","article-title":"Canine serology as adjunct to human surveillance","volume":"17","author":"Mead","year":"2011","journal-title":"Emerging Infectious Diseases"},{"key":"10.1016\/j.idm.2020.10.004_bib37","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/978-1-4615-8149-9_7","article-title":"Alzheimer disease -- A spirochetosis?","author":"Miklossy","year":"1994","journal-title":"Alzheimer Disease"},{"issue":"1","key":"10.1016\/j.idm.2020.10.004_bib38","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1186\/1756-3305-6-117","article-title":"Seropositivity rates for agents of canine vector-borne diseases in Spain: A multicentre study","volume":"6","author":"Mir\u00f3","year":"2013","journal-title":"Parasites & Vectors"},{"key":"10.1016\/j.idm.2020.10.004_bib39","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/S0140-6736(89)92612-3","article-title":"Borrelia burgdorferi infection in UK Workers at risk of tick bites","author":"Morgan-Capner","year":"1989","journal-title":"The Lancet"},{"issue":"8527","key":"10.1016\/j.idm.2020.10.004_bib40","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/S0140-6736(87)90074-2","article-title":"Emerging pattern of Lyme disease in the United Kingdom and Irish republic","volume":"329","author":"Muhlemann","year":"1987","journal-title":"The Lancet"},{"key":"10.1016\/j.idm.2020.10.004_bib41","first-page":"2","article-title":"Evaluating frequency , diagnostic quality and cost of Lyme borreliosis testing in Germany\u202f: A retrospective model analysis","author":"M\u00fcller","year":"2012","journal-title":"Molecular Microbiology"},{"issue":"9","key":"10.1016\/j.idm.2020.10.004_bib42","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.3201\/eid2109.150417","article-title":"Incidence of clinician-diagnosed Lyme disease","volume":"21","author":"Nelson","year":"2015","journal-title":"Emerging Infectious Diseases"},{"issue":"8","key":"10.1016\/j.idm.2020.10.004_bib43","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/0046-8177(89)90068-3","article-title":"Concurrent neuroborreliosis and alzheimer\u2019s disease: Analysis of the evidence","volume":"20","author":"Pappolla","year":"1989","journal-title":"Human Pathology"},{"issue":"10","key":"10.1016\/j.idm.2020.10.004_bib44","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1007\/s00436-017-5574-z","article-title":"Seroprevalence and risk factors associated with Ehrlichia canis, Anaplasma spp., Borrelia burgdorferi sensu lato, and D. immitis in hunting dogs from southern Italy","volume":"116","author":"Piantedosi","year":"2017","journal-title":"Parasitology Research"},{"issue":"2","key":"10.1016\/j.idm.2020.10.004_bib46","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1046\/j.0902-0055.2001.00100.x","article-title":"Molecular and immunological evidence of oral Treponema in the human brain and their association with Alzheimer\u2019s disease","volume":"17","author":"Riviere","year":"2002","journal-title":"Oral Microbiology and Immunology"},{"key":"10.1016\/j.idm.2020.10.004_bib47","series-title":"Borreliose - die untersch\u00e4tzte Zeckeninfection. Pressekonferenz Borreliose und FSME Bund Deutschland","article-title":"Inzidenz der Lyme-borrliose 2009 in deutschland","author":"Seifert","year":"2010"},{"issue":"2","key":"10.1016\/j.idm.2020.10.004_bib48","doi-asserted-by":"crossref","first-page":"264","DOI":"10.4269\/ajtmh.1961.10.264","article-title":"Itaqui virus, a new member of {Arthropod-Borne} group C","volume":"10","author":"Shope","year":"1961","journal-title":"The American Journal of Tropical Medicine and Hygiene"},{"issue":"2","key":"10.1016\/j.idm.2020.10.004_bib49","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.cimid.2011.12.009","article-title":"Estimating Lyme disease risk using pet dogs as sentinels","volume":"35","author":"Smith","year":"2012","journal-title":"Comparative Immunology, Microbiology and Infectious Diseases"},{"issue":"1","key":"10.1016\/j.idm.2020.10.004_bib50","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/art.1780200102","article-title":"Lyme Arthritis: An epidemic of oligoarticular arthritis in children and adults in three Connecticut communities","volume":"20","author":"Steere","year":"1977","journal-title":"Arthritis & Rheumatism"},{"issue":"5","key":"10.1016\/j.idm.2020.10.004_bib51","doi-asserted-by":"crossref","first-page":"722","DOI":"10.3201\/eid1105.040381","article-title":"Antibody testing and Lyme disease risk","volume":"11","author":"Stone","year":"2005","journal-title":"Emerging Infectious Diseases"},{"issue":"1","key":"10.1016\/j.idm.2020.10.004_bib52","first-page":"1","article-title":"An estimate of Lyme borreliosis incidence in western Europe","volume":"1","author":"Sykes","year":"2016","journal-title":"Journal of Public Health"},{"key":"10.1016\/j.idm.2020.10.004_bib53","article-title":"Charakterisierung der humoralen immunantwort im hund nach impfung mit verschiedennen Impfstoffen gegen den erreger der Lyme-borreliose, Borrelia burgdorferi, unter ber\u00fccksichtigung zweier verschiedener impfstrategien","author":"T\u00f6pfer","year":"2005","journal-title":"Inaugural-Dissertation"},{"issue":"JAN","key":"10.1016\/j.idm.2020.10.004_bib54","first-page":"1","article-title":"Estimating prevalence, demographics, and costs of ME\/CFS using large scale medical claims data and machine learning","volume":"6","author":"Valdez","year":"2019","journal-title":"Frontiers in Pediatrics"},{"key":"10.1016\/j.idm.2020.10.004_bib55","article-title":"Lyme disease in western Europe: An emerging problem? A systematic review","author":"Vandekerckhove","year":"2019","journal-title":"Acta Clinica Belgica: International Journal of Clinical and Laboratory Medicine"},{"key":"10.1016\/j.idm.2020.10.004_bib59","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/S0140-6736(15)60692-4","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: A systematic analysis for the Global Burden of Disease Study","volume":"386","author":"Vos","year":"2015","journal-title":"The Lancet"},{"issue":"10","key":"10.1016\/j.idm.2020.10.004_bib56","doi-asserted-by":"crossref","first-page":"E1029","DOI":"10.1212\/WNL.0000000000007035","article-title":"The prevalence of MS in the United States: A population-based estimate using health claims data","volume":"92","author":"Wallin","year":"2019","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.idm.2020.10.004_bib57","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.ttbdis.2015.08.009","article-title":"A\u00a0prospective study on the incidence of Borrelia burgdorferi sensu lato infection after a tick bite in Sweden and on the \u00c5land Islands, Finland (2008-2009)","volume":"7","author":"Wilhelmsson","year":"2016","journal-title":"Ticks and Tick-Borne Diseases"},{"issue":"4","key":"10.1016\/j.idm.2020.10.004_bib58","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0147-9571(99)00015-6","article-title":"Epizootiologic background of dissimilar distribution of human cases of Lyme borreliosis and tick-borne encephalitis in a joint endemic area","volume":"22","author":"Zeman","year":"1999","journal-title":"Comparative Immunology, Microbiology and Infectious Diseases"}],"container-title":["Infectious Disease Modelling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468042720300580?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468042720300580?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T04:06:04Z","timestamp":1762833964000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2468042720300580"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":58,"alternative-id":["S2468042720300580"],"URL":"https:\/\/doi.org\/10.1016\/j.idm.2020.10.004","relation":{},"ISSN":["2468-0427"],"issn-type":[{"value":"2468-0427","type":"print"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Estimates for Lyme borreliosis infections based on models using sentinel canine and human seroprevalence data","name":"articletitle","label":"Article Title"},{"value":"Infectious Disease Modelling","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.idm.2020.10.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.","name":"copyright","label":"Copyright"}]}}