{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T07:35:05Z","timestamp":1763019305463,"version":"3.45.0"},"reference-count":10,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infectious Diseases Now"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.idnow.2021.03.006","type":"journal-article","created":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T13:09:38Z","timestamp":1616591378000},"page":"682-684","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Access and use of quinacrine (mepacrine) in the treatment of resistant giardiasis"],"prefix":"10.1016","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3658-3450","authenticated-orcid":false,"given":"Clemence","family":"Delaye","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe","family":"Suarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Aguilar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corinne","family":"Guerin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Batista","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9459-3780","authenticated-orcid":false,"given":"Celine","family":"Chasport","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andre","family":"Paugam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremie","family":"Zerbit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.idnow.2021.03.006_bib0055","doi-asserted-by":"crossref","first-page":"134","DOI":"10.2174\/1872213X13666190618124901","article-title":"Giardiasis: an overview","volume":"13","author":"Leung","year":"2019","journal-title":"IAD"},{"issue":"12","key":"10.1016\/j.idnow.2021.03.006_bib0060","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/S0020-7519(00)00127-2","article-title":"Giardiasis as a re-emerging infectious disease and its zoonotic potential","volume":"30","author":"Thompson","year":"2000","journal-title":"Int J Parasitol"},{"issue":"11","key":"10.1016\/j.idnow.2021.03.006_bib0065","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.pt.2017.08.001","article-title":"The intersection of immune responses, microbiota, and pathogenesis in Giardiasis","volume":"33","author":"Fink","year":"2017","journal-title":"Trends Parasitol"},{"issue":"8","key":"10.1016\/j.idnow.2021.03.006_bib0070","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.cmi.2015.04.019","article-title":"Increased incidence of nitroimidazole-refractory giardiasis at the hospital for tropical diseases, London: 2008\u20132013","volume":"21","author":"Nabarro","year":"2015","journal-title":"Clin Microbiol Infect"},{"issue":"2","key":"10.1016\/j.idnow.2021.03.006_bib0075","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.tmaid.2012.10.004","article-title":"Refractory giardiasis in Spanish travellers","volume":"11","author":"Mu\u00f1oz Guti\u00e9rrez","year":"2013","journal-title":"Travel Med Infect Dis"},{"issue":"4","key":"10.1016\/j.idnow.2021.03.006_bib0080","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.jinf.2008.01.013","article-title":"Treatment-ladder and genetic characterisation of parasites in refractory giardiasis after an outbreak in Norway","volume":"56","author":"M\u00f8rch","year":"2008","journal-title":"Journal of Infection. 1 avr"},{"key":"10.1016\/j.idnow.2021.03.006_bib0085","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.2147\/IDR.S141468","article-title":"Treatment-refractory giardiasis: challenges and solutions","volume":"11","author":"Lalle","year":"2018","journal-title":"IDR"},{"issue":"1","key":"10.1016\/j.idnow.2021.03.006_bib0090","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1128\/CMR.14.1.114-128.2001","article-title":"Treatment of Giardiasis","volume":"14","author":"Gardner","year":"2001","journal-title":"Clin Microbiol Rev"},{"issue":"1","key":"10.1016\/j.idnow.2021.03.006_bib0095","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.cmi.2017.05.028","article-title":"Nitroimidazole-refractory giardiasis: a growing problem requiring rational solutions","volume":"24","author":"Carter","year":"2018","journal-title":"Clin Microbiol Infect"},{"issue":"6","key":"10.1016\/j.idnow.2021.03.006_bib0100","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1093\/infdis\/jix066","article-title":"The use of quinacrine in Nitroimidazole-resistant Giardia duodenalis: an old drug for an emerging problem","volume":"215","author":"Requena-M\u00e9ndez","year":"2017","journal-title":"J Infect Dis"}],"container-title":["Infectious Diseases Now"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666991921000683?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666991921000683?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T07:31:40Z","timestamp":1763019100000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666991921000683"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S2666991921000683"],"URL":"https:\/\/doi.org\/10.1016\/j.idnow.2021.03.006","relation":{},"ISSN":["2666-9919"],"issn-type":[{"type":"print","value":"2666-9919"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Access and use of quinacrine (mepacrine) in the treatment of resistant giardiasis","name":"articletitle","label":"Article Title"},{"value":"Infectious Diseases Now","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.idnow.2021.03.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}