{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T16:11:34Z","timestamp":1792080694238,"version":"4.4.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infectious Diseases Now"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.idnow.2021.05.006","type":"journal-article","created":{"date-parts":[[2021,6,6]],"date-time":"2021-06-06T19:13:09Z","timestamp":1623006789000},"page":"82-86","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Epidemiology and clinical characteristics of Klebsiella spp. meningitis in France"],"prefix":"10.1016","volume":"52","author":[{"given":"B.","family":"Pilmis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7432-1657","authenticated-orcid":false,"given":"G.","family":"P\u00e9an de Ponfilly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Farfour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.-G.","family":"Ranc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Fihman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9172-0510","authenticated-orcid":false,"given":"E.","family":"Bille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Dortet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Degand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Morand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Potron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Mizrahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Laurent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Le Brun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Guillard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"H\u00e9ry-Arnaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Piau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2015-9206","authenticated-orcid":false,"given":"O.","family":"Barraud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Ruffier d\u2019Epenoux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.-R.","family":"Zahar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Le Monnier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.idnow.2021.05.006_bib0150","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1086\/432944","article-title":"Bacterial meningitis in children: a French prospective study","volume":"41","author":"Bingen","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.idnow.2021.05.006_bib0155","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1056\/NEJMoa040845","article-title":"Clinical features and prognostic factors in adults with bacterial meningitis","volume":"351","author":"van de Beek","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.idnow.2021.05.006_bib0160","doi-asserted-by":"crossref","first-page":"e105294","DOI":"10.1371\/journal.pone.0105294","article-title":"Neurological complications after neonatal bacteremia: the clinical characteristics, risk factors, and outcomes","volume":"9","author":"Chu","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.idnow.2021.05.006_bib0165","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.ncl.2018.06.007","article-title":"Acute community-acquired bacterial meningitis","volume":"36","author":"Figueiredo","year":"2018","journal-title":"Neurol Clin"},{"key":"10.1016\/j.idnow.2021.05.006_bib0170","first-page":"311","article-title":"Clinical spectrum and molecular characteristics of Klebsiella pneumoniae causing community-acquired extrahepatic abscess","volume":"41","author":"Ku","year":"2008","journal-title":"J Microbiol Immunol Infect Wei Mian Yu Gan Ran Za Zhi"},{"key":"10.1016\/j.idnow.2021.05.006_bib0175","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1007\/s15010-006-4144-6","article-title":"Bacterial meningitis in young adults in Southern Taiwan: clinical characteristics and therapeutic outcomes","volume":"34","author":"Tsai","year":"2006","journal-title":"Infection"},{"key":"10.1016\/j.idnow.2021.05.006_bib0180","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.arcped.2018.09.013","article-title":"Klebsiella pneumoniae and Klebsiella oxytoca meningitis in infants. Epidemiological and clinical features","volume":"26","author":"Carrie","year":"2019","journal-title":"Arch Pediatr Organe"},{"key":"10.1016\/j.idnow.2021.05.006_bib0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-017-06878-6","article-title":"Klebsiella pneumoniae isolates from meningitis: epidemiology, virulence and antibiotic resistance","volume":"7","author":"Ku","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.idnow.2021.05.006_bib0190","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.3201\/eid1609.100386","article-title":"Invasive Klebsiella pneumoniae infections, California, USA","volume":"16","author":"McCabe","year":"2010","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.idnow.2021.05.006_bib0195","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1099\/jmm.0.46964-0","article-title":"Genetically similar isolates of Klebsiella pneumoniae serotype K1 causing liver abscesses in three continents","volume":"56","author":"Turton","year":"2007","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.idnow.2021.05.006_bib0200","doi-asserted-by":"crossref","first-page":"3012","DOI":"10.1128\/JCM.00676-11","article-title":"Emerging severe and fatal infections due to Klebsiella pneumoniae in two university hospitals in France","volume":"49","author":"Decr\u00e9","year":"2011","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.idnow.2021.05.006_bib0205","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1099\/jmm.0.000788","article-title":"Hypervirulent Klebsiella pneumoniae, a 5-year study in a French ICU","volume":"67","author":"Rafat","year":"2018","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.idnow.2021.05.006_bib0210","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1054\/jocn.2001.1032","article-title":"Klebsiella meningitis in adults: clinical features, prognostic factors and therapeutic outcomes","volume":"9","author":"Lu","year":"2002","journal-title":"J Clin Neurosci"},{"key":"10.1016\/j.idnow.2021.05.006_bib0215","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1017\/S0950268897007930","article-title":"Klebsiella meningitis in Taiwan: an overview","volume":"119","author":"Tang","year":"1997","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.idnow.2021.05.006_bib0230","series-title":"Standard operating procedures for enhanced meningitis surveillance in Africa","author":"World Health Organization","year":"2009"},{"key":"10.1016\/j.idnow.2021.05.006_bib0235","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1097\/00000441-194706000-00005","article-title":"Streptomycin in the treatment of certain gram-negative bacillus infections of the central nervous system","volume":"213","author":"Paine","year":"1947","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.idnow.2021.05.006_bib0240","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/S0140-6736(48)91031-9","article-title":"Streptomycin treatment of meningitis due to gram-negative saprophytes","volume":"2","author":"Lewin","year":"1948","journal-title":"Lancet Lond Engl"},{"key":"10.1016\/j.idnow.2021.05.006_bib0245","doi-asserted-by":"crossref","first-page":"253","DOI":"10.7326\/0003-4819-93-2-253","article-title":"Meningitis caused by gram-negative bacilli","volume":"93","author":"Berk","year":"1980","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.idnow.2021.05.006_bib0250","doi-asserted-by":"crossref","first-page":"468","DOI":"10.7326\/0003-4819-96-4-468","article-title":"Host defense and antimicrobial therapy in adult gram-negative bacillary meningitis","volume":"96","author":"Rahal","year":"1982","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.idnow.2021.05.006_bib0255","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1056\/NEJM199301073280104","article-title":"Acute bacterial meningitis in adults. A review of 493 episodes","volume":"328","author":"Durand","year":"1993","journal-title":"N Engl J Med"},{"issue":"Suppl. 2","key":"10.1016\/j.idnow.2021.05.006_bib0260","first-page":"532","article-title":"Risk factors for adult nosocomial meningitis after craniotomy: role of antibiotic prophylaxis","volume":"62","author":"Korinek","year":"2008","journal-title":"Neurosurgery"},{"key":"10.1016\/j.idnow.2021.05.006_bib0265","doi-asserted-by":"crossref","first-page":"e34","DOI":"10.1093\/cid\/ciw861","article-title":"2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis","volume":"64","author":"Tunkel","year":"2017","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.idnow.2021.05.006_bib0270","doi-asserted-by":"crossref","first-page":"R142","DOI":"10.1186\/cc7119","article-title":"Determinants and impact of multidrug antibiotic resistance in pathogens causing ventilator-associated-pneumonia","volume":"12","author":"Depuydt","year":"2008","journal-title":"Crit Care"},{"key":"10.1016\/j.idnow.2021.05.006_bib0275","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1093\/cid\/ciw504","article-title":"Executive summary: management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society","volume":"63","author":"Kalil","year":"2016","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.idnow.2021.05.006_bib0280","doi-asserted-by":"crossref","first-page":"4512","DOI":"10.1128\/AAC.00238-13","article-title":"Relative fecal abundance of extended-spectrum-\u03b2-lactamase-producing Escherichia coli strains and their occurrence in urinary tract infections in women","volume":"57","author":"Rupp\u00e9","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.idnow.2021.05.006_bib0285","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s13613-017-0283-4","article-title":"Frequency, associated factors and outcome of multidrug-resistant intensive care unit-acquired pneumonia among patients colonized with extended-spectrum \u03b2-lactamase-producing Enterobacteriaceae","volume":"7","author":"Razazi","year":"2017","journal-title":"Ann Intensive Care"}],"container-title":["Infectious Diseases Now"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666991921001159?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666991921001159?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T07:30:40Z","timestamp":1763019040000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666991921001159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["S2666991921001159"],"URL":"https:\/\/doi.org\/10.1016\/j.idnow.2021.05.006","relation":{},"ISSN":["2666-9919"],"issn-type":[{"value":"2666-9919","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Epidemiology and clinical characteristics of Klebsiella spp. meningitis in France","name":"articletitle","label":"Article Title"},{"value":"Infectious Diseases Now","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.idnow.2021.05.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}