{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T08:07:35Z","timestamp":1758960455316,"version":"3.44.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,4,14]],"date-time":"2016-04-14T00:00:00Z","timestamp":1460592000000},"content-version":"vor","delay-in-days":1079,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Integrated Tribal Development Project, India"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Indian Heart Journal"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1016\/j.ihj.2013.04.012","type":"journal-article","created":{"date-parts":[[2013,4,9]],"date-time":"2013-04-09T21:15:43Z","timestamp":1365542143000},"page":"295-299","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Elevated levels of leukotriene B4 and thromboxane B2 distinguish chest pain of cardiac and non cardiac origin"],"prefix":"10.1016","volume":"65","author":[{"given":"Febi","family":"John","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Kavitha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seema","family":"Panicker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiny","family":"Nair","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Indira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ihj.2013.04.012_bib1","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3164\/jcbn.2007007","article-title":"Serum cardiac markers in patients with acute myocardial infarction: oxidative stress, C-reactive protein and N-terminal probrain natriuretic peptide","volume":"41","author":"Kasap","year":"2011","journal-title":"J Clin Biochem Nutr"},{"key":"10.1016\/j.ihj.2013.04.012_bib2","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1152\/ajpregu.00170.2003","article-title":"C-reactive protein and atherothrombosis \u2013 beyond a biomarker: an actual partaker of lesion formation","volume":"285","author":"Verma","year":"2003","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.ihj.2013.04.012_bib3","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1161\/01.CIR.0000089190.95415.9F","article-title":"New markers of inflammation and endothelial cell activation","volume":"108","author":"Szmitko","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.ihj.2013.04.012_bib4","first-page":"4137","article-title":"C-reactive protein and other inflammatory risk markers in acute coronary syndromes","author":"Blake","year":"2003","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.ihj.2013.04.012_bib5","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1056\/NEJMoa025079","article-title":"Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis","volume":"350","author":"Dwyer","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ihj.2013.04.012_bib6","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1161\/01.ATV.0000252680.72734.10","article-title":"Association between a leukotriene C4 synthase gene promoter polymorphism and coronary artery calcium in young women: the Muscatine study","volume":"27","author":"Iovannisci","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.ihj.2013.04.012_bib7","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/ng1311","article-title":"The gene\u00a0encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke","volume":"36","author":"Helgadottir","year":"2004","journal-title":"Nat Genet"},{"key":"10.1016\/j.ihj.2013.04.012_bib8","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1161\/ATVBAHA.107.158873","article-title":"Promotor polymorphisms in leukotriene C4 synthase and risk of ischemic cerebrovascular disease","volume":"28","author":"Freiberg","year":"2008","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.ihj.2013.04.012_bib9","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.atherosclerosis.2009.06.018","article-title":"Associations of genetic polymorphisms of arachidonate 5-lipoxygenase-activating protein with risk of coronary artery disease in a European\u2013American population","volume":"207","author":"Tsai","year":"2009","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ihj.2013.04.012_bib10","first-page":"782","article-title":"Dietary arachidonic acid, 5-lipoxygenase and myocardial infarction","volume":"116","author":"Hannia","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.ihj.2013.04.012_bib11","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1093\/cvr\/cvn277","article-title":"Leukotriene B4 enhances the activity of nuclear factor-kappaB pathway through BLT1 and BLT2 receptors in atherosclerosis","volume":"81","author":"Sanchez Galan","year":"2009","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.ihj.2013.04.012_bib12","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/BF00223432","article-title":"Significance of myocardial eicosanoid production","volume":"88","author":"van Bilsen","year":"1989","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.ihj.2013.04.012_bib13","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1177\/000331979604700703","article-title":"Arachidonic acid metabolites in acute myocardial infarction","volume":"47","author":"Takase","year":"1996","journal-title":"Angiology"},{"key":"10.1016\/j.ihj.2013.04.012_bib14","first-page":"265","author":"Huch","year":"1996","journal-title":"Blood"},{"key":"10.1016\/j.ihj.2013.04.012_bib15","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/0076-6879(81)71055-3","volume":"71","author":"Axelrod","year":"1981","journal-title":"Meth Enzymol"},{"key":"10.1016\/j.ihj.2013.04.012_bib16","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0003-9861(81)90091-6","article-title":"Role of prostaglandin endoperoxides in the serum thiobarbituric acid reaction","volume":"206","author":"Shimazu","year":"1981","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.ihj.2013.04.012_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0021-9150(96)05851-0","article-title":"Lipids, risk factors and ischaemic heart disease","volume":"124","author":"Castelli","year":"1996","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ihj.2013.04.012_bib18","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1056\/NEJMoa021993","article-title":"Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events","volume":"347","author":"Ridker","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ihj.2013.04.012_bib19","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1073\/pnas.242716099","article-title":"Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis","volume":"100","author":"Spanbroek","year":"2003","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.ihj.2013.04.012_bib20","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1038\/nm1099","article-title":"The 5-lipoxygenase pathway arachidonic acid metabolites in acute myocardial infarction","volume":"10","author":"Zhao","year":"2004","journal-title":"Nat Med"},{"key":"10.1016\/j.ihj.2013.04.012_bib21","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.atherosclerosis.2008.07.025","article-title":"Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene and coronary heart disease risk in familial hypercholesterolemia","volume":"203","author":"van der Net","year":"2009","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ihj.2013.04.012_bib22","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1161\/01.CIR.98.2.100","article-title":"Induction of cyclooxygenase-2 and activation of nuclear factor-kappaB in myocardium of patients with congestive heart failure","volume":"98","author":"Wong","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.ihj.2013.04.012_bib23","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1160\/TH10-08-0550","article-title":"Residual cyclooxygenase-1 activity and epinephrine reduce the antiplatelet effect of aspirin in patients with acute myocardial infarction","volume":"105","author":"Moscardo","year":"2011","journal-title":"Thromb Haemost"}],"container-title":["Indian Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0019483213001016?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0019483213001016?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T03:46:21Z","timestamp":1758080781000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0019483213001016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["S0019483213001016"],"URL":"https:\/\/doi.org\/10.1016\/j.ihj.2013.04.012","relation":{},"ISSN":["0019-4832"],"issn-type":[{"type":"print","value":"0019-4832"}],"subject":[],"published":{"date-parts":[[2013,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Elevated levels of leukotriene B4 and thromboxane B2 distinguish chest pain of cardiac and non cardiac origin","name":"articletitle","label":"Article Title"},{"value":"Indian Heart Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ihj.2013.04.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Cardiological Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}