{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:10:50Z","timestamp":1786990250782,"version":"build-2736575974"},"reference-count":25,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,4,10]],"date-time":"2020-04-10T00:00:00Z","timestamp":1586476800000},"content-version":"vor","delay-in-days":40,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Indian Heart Journal"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.ihj.2020.04.002","type":"journal-article","created":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T11:02:02Z","timestamp":1586948522000},"page":"101-106","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Implication of d-dimer in rheumatic severe mitral stenosis \u2013 A tertiary centre study"],"prefix":"10.1016","volume":"72","author":[{"given":"Kiron","family":"Sukulal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishna Kumar","family":"Mohanan Nair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bijulal","family":"Sasidharan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajitkumar","family":"Valaparambil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Ganapathi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sivasankaran","family":"Sivasubramanian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harikrishnan","family":"Sivadasanpillai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.ihj.2020.04.002_bib1","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1378\/chest.106.2.396","article-title":"Noninvasive predictors of systemic embolism in mitral stenosis: an echocardiographic and clinical study of 500 patients","volume":"106","author":"Chiang","year":"1994","journal-title":"Chest"},{"issue":"2","key":"10.1016\/j.ihj.2020.04.002_bib2","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/0735-1097(93)90688-W","article-title":"Hematologic correlates of left atrial spontaneous echo contrast and thromboembolism in nonvalvular atrial fibrillation","volume":"21","author":"Black","year":"1993","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"11","key":"10.1016\/j.ihj.2020.04.002_bib3","doi-asserted-by":"crossref","first-page":"817","DOI":"10.7326\/0003-4819-123-11-199512010-00001","article-title":"Accuracy of transesophageal echocardiography for identifying left atrial thrombi: a prospective, intraoperative study","volume":"123","author":"Manning","year":"1995","journal-title":"Ann Intern Med"},{"issue":"3","key":"10.1016\/j.ihj.2020.04.002_bib4","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1055\/s-0038-1650288","article-title":"Evaluation of a new rapid quantitative D-dimer assay in patients with clinically suspected deep vein thrombosis","volume":"75","author":"D'Angelo","year":"1996","journal-title":"Thromb Haemostasis"},{"issue":"8","key":"10.1016\/j.ihj.2020.04.002_bib5","doi-asserted-by":"crossref","first-page":"589","DOI":"10.7326\/0003-4819-140-8-200404200-00005","article-title":"D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism: a systematic review","volume":"140","author":"Stein","year":"2004","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ihj.2020.04.002_bib6","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0002-9149(03)00476-4","article-title":"D-dimer determination as a screening tool to exclude atrial thrombi in atrial fibrillation","volume":"92","author":"Somloi","year":"2003","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ihj.2020.04.002_bib7","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1093\/eurheartj\/ehm356","article-title":"Prediction of left atrial appendage thrombi in nonvalvular atrial fibrillation","volume":"28","author":"Habara","year":"2007","journal-title":"Eur Heart J"},{"issue":"1","key":"10.1016\/j.ihj.2020.04.002_bib8","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1046\/j.1365-2141.2003.04723.x","volume":"124","author":"Keeling","year":"2004","journal-title":"Br J Haematol"},{"issue":"1","key":"10.1016\/j.ihj.2020.04.002_bib9","first-page":"1","article-title":"Plasma measurement of D-dimer as diagnostic aid in suspected venous thromboembolism: an overview","volume":"72","author":"Bounameaux","year":"1994","journal-title":"Thromb Haemostasis"},{"issue":"2","key":"10.1016\/j.ihj.2020.04.002_bib10","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0005-2736(91)90047-C","article-title":"Erythrocyte aggregation: bridging by macromolecules and electrostatic repulsion by sialic acid","volume":"1067","author":"Izumida","year":"1991","journal-title":"Biochim Biophys Acta Biomembr"},{"issue":"5","key":"10.1016\/j.ihj.2020.04.002_bib11","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1182\/blood.V70.5.1572.1572","article-title":"Mechanism of erythrocyte aggregation and sedimentation","volume":"70","author":"Fabry","year":"1987","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.ihj.2020.04.002_bib12","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1161\/01.CIR.66.4.755","article-title":"Regional stasis of blood in the dysfunctional left ventricle: echocardiographic detection and differentiation from early thrombosis","volume":"66","author":"Mikell","year":"1982","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.ihj.2020.04.002_bib13","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1111\/j.1540-8175.2000.tb01153.x","article-title":"Spontaneous echo contrast: where there's smoke there's fire","volume":"17","author":"Black","year":"2000","journal-title":"Echocardiography"},{"issue":"7","key":"10.1016\/j.ihj.2020.04.002_bib14","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1016\/S0735-1097(00)00643-4","article-title":"Clinical and echocardiographic characteristics of left atrial spontaneous echo contrast in sinus rhythm","volume":"35","author":"Sadanandan","year":"2000","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.ihj.2020.04.002_bib15","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1055\/s-0038-1648831","article-title":"D-dimer levels in patients with long-term antecedents of deep venous thrombosis","volume":"72","author":"Sie","year":"1994","journal-title":"Thromb Haemostasis"},{"issue":"2","key":"10.1016\/j.ihj.2020.04.002_bib16","first-page":"316","article-title":"Predictive value of D-dimer levels and tissue Doppler mitral annular systolic velocity for detection of left atrial appendage thrombus in patients with mitral stenosis in sinus rhythm","volume":"5","author":"Abd El Salam","year":"2011","journal-title":"Heart Mirror J"},{"issue":"suppl_A","key":"10.1016\/j.ihj.2020.04.002_bib17","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/eurheartj\/16.suppl_A.47","article-title":"Therapeutic interventions to lower plasma fibrinogen concentration","volume":"16","author":"Ernst","year":"1995","journal-title":"Eur Heart J"},{"issue":"1","key":"10.1016\/j.ihj.2020.04.002_bib18","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0002-8703(95)90044-6","article-title":"Resolution of left atrial spontaneous echocardiographic contrast after percutaneous mitral valvuloplasty: implications for thromboembolic risk","volume":"129","author":"Leung","year":"1995","journal-title":"Am Heart J"},{"issue":"1","key":"10.1016\/j.ihj.2020.04.002_bib19","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1136\/hrt.32.1.26","article-title":"Systemic embolism in mitral valve disease","volume":"32","author":"Coulshed","year":"1970","journal-title":"Br Heart J"},{"issue":"10","key":"10.1016\/j.ihj.2020.04.002_bib20","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1002\/clc.4960171007","article-title":"Spontaneous echo contrast on transthoracic echocardiography and left atrial thrombus in rheumatic mitral valve disease patients: a clinicopathologic study","volume":"17","author":"Wanishsawad","year":"1994","journal-title":"Clin Cardiol"},{"issue":"4","key":"10.1016\/j.ihj.2020.04.002_bib21","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/S0735-1097(85)80476-9","article-title":"Smoke-like echo in the left atrial cavity in mitral valve disease: its features and significance","volume":"6","author":"Beppu","year":"1985","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"3","key":"10.1016\/j.ihj.2020.04.002_bib22","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1136\/hrt.74.3.296","article-title":"A\u00a0study of spontaneous echo contrast in patients with rheumatic mitral stenosis and normal sinus rhythm: an Indian perspective","volume":"74","author":"Kasliwal","year":"1995","journal-title":"Heart"},{"issue":"6","key":"10.1016\/j.ihj.2020.04.002_bib23","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/0735-1097(88)90283-5","article-title":"Left atrial spontaneous echo contrast in mitral valve disease: an indicator for an increased thromboembolic risk","volume":"11","author":"Daniel","year":"1988","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.ihj.2020.04.002_bib24","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.ijcard.2005.05.049","article-title":"D-dimer level influences thromboembolic events in patients with atrial fibrillation","volume":"109","author":"Nozawa","year":"2006","journal-title":"Int J Cardiol"},{"issue":"20","key":"10.1016\/j.ihj.2020.04.002_bib25","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1016\/j.jacc.2009.12.049","article-title":"Evidence that D-dimer levels predict subsequent thromboembolic and cardiovascular events in patients with atrial fibrillation during oral anticoagulant therapy","volume":"55","author":"Sadanaga","year":"2010","journal-title":"J\u00a0Am Coll Cardiol"}],"container-title":["Indian Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0019483220300596?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0019483220300596?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T03:52:38Z","timestamp":1758081158000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0019483220300596"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["S0019483220300596"],"URL":"https:\/\/doi.org\/10.1016\/j.ihj.2020.04.002","relation":{},"ISSN":["0019-4832"],"issn-type":[{"value":"0019-4832","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Implication of d-dimer in rheumatic severe mitral stenosis \u2013 A tertiary centre study","name":"articletitle","label":"Article Title"},{"value":"Indian Heart Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ihj.2020.04.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Cardiological Society of India. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}