{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T20:29:44Z","timestamp":1787084984933,"version":"build-2736575974"},"reference-count":22,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007338","name":"All-India Institute of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007338","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Indian Heart Journal"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.ihj.2026.03.002","type":"journal-article","created":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T08:13:04Z","timestamp":1772784784000},"page":"187-191","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Primary aldosteronism in premature coronary artery disease: A cross-sectional study from a tertiary center in India"],"prefix":"10.1016","volume":"78","author":[{"given":"Manish","family":"Thakur","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manasvini","family":"Bhatt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alpesh","family":"Goyal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambuj","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Alam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8193-2779","authenticated-orcid":false,"given":"Rajesh","family":"Khadgawat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ihj.2026.03.002_bib1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.3803\/EnM.2018.33.4.429","article-title":"Primary aldosteronism and cerebrovascular diseases","volume":"33","author":"Chen","year":"2018","journal-title":"Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.ihj.2026.03.002_bib2","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1007\/s11906-010-0134-2","article-title":"Prevalence and diagnosis of primary aldosteronism","volume":"12","author":"Rossi","year":"2010","journal-title":"Curr Hypertens Rep"},{"issue":"9","key":"10.1016\/j.ihj.2026.03.002_bib3","doi-asserted-by":"crossref","first-page":"4803","DOI":"10.3390\/ijms23094803","article-title":"Primary aldosteronism and resistant hypertension: a pathophysiological insight","volume":"23","author":"Bioletto","year":"2022","journal-title":"Int J Mol Sci"},{"issue":"8","key":"10.1016\/j.ihj.2026.03.002_bib4","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s11886-021-01538-8","article-title":"Primary aldosteronism: a continuum from normotension to hypertension","volume":"23","author":"Wannachalee","year":"2021","journal-title":"Curr Cardiol Rep"},{"key":"10.1016\/j.ihj.2026.03.002_bib5","doi-asserted-by":"crossref","DOI":"10.3390\/ijms17070797","article-title":"Role of the renin-angiotensin-aldosterone system beyond blood pressure regulation: molecular and cellular mechanisms involved in end-organ damage during arterial hypertension","author":"Mu\u00f1oz-Durango","year":"2016","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.ihj.2026.03.002_bib6","article-title":"Aldosterone stimulates proliferation of cardiac fibroblasts by activating Ki-RasA and MAPK1\/2 signaling","author":"Stock","year":"2003","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.ihj.2026.03.002_bib7","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1161\/HYPERTENSIONAHA.114.04488","article-title":"Mineralocorticoid receptor activation and mineralocorticoid receptor antagonist treatment in cardiac and renal diseases","volume":"65","author":"Bauersachs","year":"2015","journal-title":"Hypertension"},{"issue":"2","key":"10.1016\/j.ihj.2026.03.002_bib8","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.ijcard.2008.04.020","article-title":"Premature coronary artery disease in young subjects: interactions of lipid profile, thrombophilic and haemostatic markers","volume":"136","author":"Pineda","year":"2009","journal-title":"Int J Cardiol"},{"issue":"3","key":"10.1016\/j.ihj.2026.03.002_bib9","first-page":"217","article-title":"Premature coronary artery disease in Indians and its associated risk factors","volume":"1","author":"Sharma","year":"2005","journal-title":"Vasc Health Risk Manag"},{"key":"10.1016\/j.ihj.2026.03.002_bib10","article-title":"A retrospective case- control study of modifiable risk factors and cutaneous markers in Indian patients with young coronary artery disease","author":"Aggarwal","year":"2012","journal-title":"JRSM Cardiovasc Dis"},{"issue":"8","key":"10.1016\/j.ihj.2026.03.002_bib11","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.jacc.2005.01.015","article-title":"Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism","volume":"45","author":"Milliez","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ihj.2026.03.002_bib12","first-page":"41","article-title":"Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and metaanalysis","volume":"6","author":"Monticone","year":"2018","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.ihj.2026.03.002_bib13","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1136\/jnnp-2013-306203","article-title":"Trends in the incidence of ischaemic stroke in young adults between 1985 and 2011: the Dijon Stroke Registry","volume":"85","author":"B\u00e9jot","year":"2014","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.ihj.2026.03.002_bib14","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1038\/s41371-020-0336-2","article-title":"Primary aldosteronism is a public health issue: challenges and opportunities","volume":"34","author":"Libianto","year":"2020","journal-title":"J Hum Hypertens"},{"key":"10.1016\/j.ihj.2026.03.002_bib15","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1001\/archinternmed.2007.33","article-title":"Cardiovascular outcomes in patients with primary aldosteronism after treatment","volume":"168","author":"Catena","year":"2008","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.ihj.2026.03.002_bib16","article-title":"Cardiovascular risk in primary aldosteronism: a systematic review and meta-analysis","volume":"98","author":"Wu","year":"2019","journal-title":"Medicine"},{"issue":"1","key":"10.1016\/j.ihj.2026.03.002_bib17","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S2213-8587(17)30367-4","article-title":"Cardiometabolic outcomes and mortality in medically treated primary aldosteronism: a retrospective cohort study","volume":"6","author":"Hundemer","year":"2018","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"12","key":"10.1016\/j.ihj.2026.03.002_bib18","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1097\/HJH.0000000000003480","volume":"41","author":"Mancia","year":"2023","journal-title":"J Hypertens"},{"issue":"5","key":"10.1016\/j.ihj.2026.03.002_bib19","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1210\/jc.2015-4061","article-title":"The management of primary aldosteronism : case detection, detection diagnosis and treatment: an endocrine society clinical practice guideline","volume":"101","author":"Funder","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"issue":"9","key":"10.1016\/j.ihj.2026.03.002_bib20","doi-asserted-by":"crossref","first-page":"2453","DOI":"10.1210\/clinem\/dgaf284","article-title":"Primary aldosteronism: an endocrine society clinical practice guideline","volume":"110","author":"Adler","year":"2025","journal-title":"J Clin Endocrinol Metabol"},{"issue":"1","key":"10.1016\/j.ihj.2026.03.002_bib21","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1210\/clinem\/dgac568","article-title":"Aldosterone, renin, and aldosterone-to-renin ratio variability in screening for primary aldosteronism","volume":"108","author":"Ng","year":"2022","journal-title":"J Clin Endocrinol Metab"},{"issue":"3","key":"10.1016\/j.ihj.2026.03.002_bib22","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1161\/HYPERTENSIONAHA.120.16429","article-title":"Intraindividual variability of aldosterone concentrations in primary aldosteronism: implications for case detection","volume":"77","author":"Yozamp","year":"2021","journal-title":"Hypertension"}],"container-title":["Indian Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0019483226000337?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0019483226000337?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T20:03:54Z","timestamp":1787083434000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0019483226000337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S0019483226000337"],"URL":"https:\/\/doi.org\/10.1016\/j.ihj.2026.03.002","relation":{},"ISSN":["0019-4832"],"issn-type":[{"value":"0019-4832","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Primary aldosteronism in premature coronary artery disease: A cross-sectional study from a tertiary center in India","name":"articletitle","label":"Article Title"},{"value":"Indian Heart Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ihj.2026.03.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier, a division of RELX India, Pvt. Ltd on behalf of Cardiological Society of India.","name":"copyright","label":"Copyright"}]}}