{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T02:18:03Z","timestamp":1792117083882,"version":"4.4.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Antimicrobial Agents"],"published-print":{"date-parts":[[2007,11]]},"DOI":"10.1016\/j.ijantimicag.2007.06.019","type":"journal-article","created":{"date-parts":[[2007,8,23]],"date-time":"2007-08-23T11:16:05Z","timestamp":1187867765000},"page":"385-389","source":"Crossref","is-referenced-by-count":113,"title":["The changing face of Klebsiella pneumoniae infections in the community"],"prefix":"10.1016","volume":"30","author":[{"given":"Yoav","family":"Keynan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ethan","family":"Rubinstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijantimicag.2007.06.019_bib1","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1086\/499968","article-title":"Genetic determinants of capsular serotype K1 of Kp causing primary pyogenic liver abscess","volume":"193","author":"Chuang","year":"2006","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib2","doi-asserted-by":"crossref","first-page":"160","DOI":"10.3201\/eid0802.010025","article-title":"Community-acquired Klebsiella pneumoniae bacteremia: global differences in clinical patterns","volume":"8","author":"Ko","year":"2002","journal-title":"Emerg Infect Dis"},{"issue":"39","key":"10.1016\/j.ijantimicag.2007.06.019_bib3","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1086\/425616","article-title":"Pyogenic liver abscess: recent trends in etiology and mortality","volume":"1","author":"Rahimian","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib4","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1128\/JCM.43.2.991-992.2005","article-title":"Liver abscess caused by magA+ Klebsiella pneumonia in North America","volume":"43","author":"Fang","year":"2005","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib5","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1017\/S0950268897007930","article-title":"Klebsiella meningitis in Taiwan: an overview","volume":"119","author":"Tang","year":"1997","journal-title":"Epidemiol Infect"},{"issue":"2","key":"10.1016\/j.ijantimicag.2007.06.019_bib6","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1093\/jac\/dkl483","article-title":"CTX-M: changing the face of ESBLs in Europe","volume":"59","author":"Livermore","year":"2007","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib7","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1001\/archinte.151.8.1557","article-title":"Septic metastatic lesions of pyogenic liver abscess. Their association with Klebsiella pneumonia bacteremia in diabetic patients","volume":"151","author":"Cheng","year":"1991","journal-title":"Arch Intern Med"},{"issue":"2","key":"10.1016\/j.ijantimicag.2007.06.019_bib8","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1111\/j.1572-0241.2005.40310.x","article-title":"Pyogenic liver abscess with a focus on Kp as a primary pathogen: an emerging disease with unique clinical characteristics","volume":"100","author":"Lederman","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib9","unstructured":"Keynan Y, Karlowsky JA, Walus T, Rubinstein E. Pyogenic liver abscess caused by hypermucoviscous Kp. Scand J Inf Dis, in press"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib10","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/j.micinf.2004.06.003","article-title":"High prevalence of phagocytic-resistant capsular serotypes of Kp in liver abscess","volume":"6","author":"Lin","year":"2004","journal-title":"Microbes Infect"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib11","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1136\/gut.50.3.420","article-title":"A global emerging disease of Kp liver abscess: is serotype K1 an important factor for complicated endophthalmitis?","volume":"50","author":"Fung","year":"2002","journal-title":"Gut"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib12","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1111\/j.1365-2796.2006.01641.x","article-title":"Clinical implications of hypermucoviscosity phenotype in Kp isolates: association with invasive syndrome in patients with community-acquired bacteraemia","volume":"259","author":"Lee","year":"2006","journal-title":"J Intern Med"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib13","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1084\/jem.20030857","article-title":"A novel virulence gene in Kp strains causing primary liver abscess and septic metastatic complications","volume":"199","author":"Fang","year":"2004","journal-title":"J Exp Med"},{"issue":"42","key":"10.1016\/j.ijantimicag.2007.06.019_bib14","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1086\/503420","article-title":"Association between rmpA and magA genes and clinical syndromes caused by Kp in Taiwan","volume":"15","author":"Yu","year":"2006","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib15","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1086\/430619","article-title":"Genomic heterogeneity in Kp strains is associated with primary pyogenic liver abscess and metastatic infection","volume":"192","author":"Ma","year":"2005","journal-title":"J Infect Dis"},{"issue":"Pt 6","key":"10.1016\/j.ijantimicag.2007.06.019_bib16","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1099\/jmm.0.46368-0","article-title":"magA is not a specific virulence gene for Kp strains causing liver abscess but is part of the capsular polysaccharide gene cluster of K. pneumoniae serotype K1","volume":"55","author":"Yeh","year":"2006","journal-title":"J Med Microbiol"},{"issue":"Pt 11","key":"10.1016\/j.ijantimicag.2007.06.019_bib17","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1099\/jmm.0.46165-0","article-title":"Investigation of the putative virulence gene magA in a worldwide collection of 495 Klebsiella isolates: magA is restricted to the gene cluster of Kp capsule serotype K1","volume":"54","author":"Struve","year":"2005","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib18","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0732-8893(02)00470-4","article-title":"Urinary tract infection trends in Latin American hospitals: report from the SENTRY antimicrobial surveillance program (1997\u20132000)","volume":"44","author":"Gales","year":"2002","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib19","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1007\/s00134-002-1521-1","article-title":"Extended-spectrum beta-lactamase-producing Escherichia coli and Kp bloodstream infection: risk factors and clinical outcome","volume":"28","author":"Du","year":"2002","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib20","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1086\/319757","article-title":"Extended-spectrum \u03b2-lactamase-producing Escherichia coli and Kp: risk factors for infection and impact of resistance on outcomes","volume":"32","author":"Lautenbach","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib21","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1128\/AAC.46.2.602-604.2002","article-title":"Early dissemination of CTX-M-derived enzymes in South America","volume":"46","author":"Radice","year":"2002","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib22","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.ijantimicag.2003.07.004","article-title":"Dissemination of CTX-M type \u03b2-lactamases in Enterobacteriaceae isolates in the People's Republic of China","volume":"23","author":"Munday","year":"2004","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib23","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1093\/jac\/dkf240","article-title":"Biochemical analysis of the ceftazidime-hydrolysing extended-spectrum \u03b2-lactamase CTX-M-15 and of its structurally related \u03b2-lactamase CTX-M-3","volume":"50","author":"Poirel","year":"2002","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib24","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1093\/jac\/dkg051","article-title":"An outbreak of a CTX-M-type \u03b2-lactamase-producing Kp: the importance of using cefpodoxime to detect extended-spectrum \u03b2-lactamases","volume":"51","author":"Brenwald","year":"2003","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib25","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1128\/AAC.50.1.374-378.2006","article-title":"Multicenter antimicrobial susceptibility survey of gram-negative bacteria isolated from patients with community-acquired infections in the People's Republic of China","volume":"50","author":"Ling","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib26","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1093\/jac\/dki245","article-title":"Emergence of plasmid-mediated resistance to quinolones in Enterobacteriaceae","volume":"56","author":"Nordmann","year":"2005","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib27","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1378\/chest.115.2.462","article-title":"Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients","volume":"115","author":"Kollef","year":"1999","journal-title":"Chest"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib28","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1086\/420816","article-title":"Antibiotic therapy for Kp bacteremia: implications of production of extended-spectrum beta-lactamases","volume":"39","author":"Paterson","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib29","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S1201-9712(00)90061-4","article-title":"Ceftazidime-resistant Kp bloodstream infection in children with febrile neutropenia","volume":"4","author":"Ariffin","year":"2000","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib30","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s10096-003-1084-2","article-title":"Risk factors for the development of extended-spectrum beta-lactamase-producing bacteria in nonhospitalized patients","volume":"23","author":"Colodner","year":"2004","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib31","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1093\/jac\/dki166","article-title":"Emergence of Enterobacteriaceae producing extended-spectrum beta-lactamases (ESBLs) in the community","volume":"56","author":"Pitout","year":"2005","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib32","doi-asserted-by":"crossref","first-page":"4030","DOI":"10.1128\/JCM.40.11.4030-4036.2002","article-title":"Identification and broad dissemination of the CTX-M-14 \u03b2-lactamase in different Escherichia coli strains in the northwest area of Spain","volume":"40","author":"Bou","year":"2002","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib33","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1128\/JCM.44.5.1659-1664.2006","article-title":"Trends in production of extended-spectrum beta-lactamases among enterobacteria of medical interest: report of the second Italian nationwide survey","volume":"44","author":"Luzzaro","year":"2006","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib34","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1093\/jac\/dki429","article-title":"CTX-M-15 extended-spectrum (beta)-lactamase from Nigerian Kp","volume":"57","author":"Soge","year":"2006","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib35","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1128\/AAC.41.3.563","article-title":"Imipenem resistance in Kp is associated with the combination of ACT-1, a plasmid-mediated AmpC \u03b2-lactamase, and the loss of an outer membrane protein","volume":"41","author":"Bradford","year":"1997","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib36","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.ijantimicag.2004.06.001","article-title":"Susceptibility pattern of ESBL-producing bacteria isolated from inpatients to five antimicrobial drugs in a community hospital in northern Israel","volume":"24","author":"Colodner","year":"2004","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib37","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1093\/jac\/46.6.895","article-title":"Emergence of imipenem resistance in Kp owing to combination of plasmid-mediated CMY-4 and permeability alteration","volume":"46","author":"Cao","year":"2000","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib38","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1086\/421495","article-title":"Emergence of carbapenem-resistant Klebsiella species possessing the class A carbapenem-hydrolyzing KPC-2 and inhibitor-resistant TEM-30 \u03b2-lactamases in New York city","volume":"39","author":"Bradford","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib39","doi-asserted-by":"crossref","first-page":"3018","DOI":"10.1128\/AAC.49.7.3018-3020.2005","article-title":"Emergence of KPC-possessing Kp in Brooklyn, New York: epidemiology and recommendations for detection","volume":"49","author":"Bratu","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib40","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1128\/AAC.45.4.1151-1161.2001","article-title":"Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Kp","volume":"45","author":"Yigit","year":"2001","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib41","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1093\/jac\/40.3.365","article-title":"Permeability to carbapenems of Proteus mirabilis mutants selected for resistance to imipenem or other \u03b2-lactams","volume":"40","author":"Villar","year":"1997","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib42","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1093\/jac\/dkg124","article-title":"Plasmid-mediated, carbapenem-hydrolysing beta-lactamase, KPC-2, in Kp isolates","volume":"51","author":"Smith Moland","year":"2003","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib43","doi-asserted-by":"crossref","first-page":"4793","DOI":"10.1128\/AAC.48.12.4793-4799.2004","article-title":"Outbreak of Kp producing a new carbapenem-hydrolyzing class A beta-lactamase, KPC-3, in a New York Medical Center","volume":"48","author":"Woodford","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2007.06.019_bib44","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1093\/jac\/dki175","article-title":"Carbapenemase-producing Kp in Brooklyn, NY: molecular epidemiology and in vitro activity of polymyxin B and other agents","volume":"56","author":"Bratu","year":"2005","journal-title":"J Antimicrob Chemother"}],"container-title":["International Journal of Antimicrobial Agents"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0924857907002919?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0924857907002919?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T13:29:59Z","timestamp":1556803799000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0924857907002919"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":44,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["S0924857907002919"],"URL":"https:\/\/doi.org\/10.1016\/j.ijantimicag.2007.06.019","relation":{},"ISSN":["0924-8579"],"issn-type":[{"value":"0924-8579","type":"print"}],"subject":[],"published":{"date-parts":[[2007,11]]}}}