{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T18:38:19Z","timestamp":1771007899045,"version":"3.50.1"},"reference-count":25,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Antimicrobial Agents"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1016\/j.ijantimicag.2008.07.017","type":"journal-article","created":{"date-parts":[[2008,10,2]],"date-time":"2008-10-02T09:14:09Z","timestamp":1222938849000},"page":"52-57","source":"Crossref","is-referenced-by-count":23,"title":["Susceptibility patterns of bacterial isolates from hospitalised patients with respiratory tract infections (MOXIAKTIV Study)"],"prefix":"10.1016","volume":"33","author":[{"given":"Enno","family":"Jacobs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Dalhoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gisela","family":"Korfmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijantimicag.2008.07.017_bib1","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1038\/146837a0","article-title":"An enzyme from bacteria able to destroy penicillin","volume":"146","author":"Abraham","year":"1940","journal-title":"Nature"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib2","series-title":"Beitr\u00e4ge zur Arzneimitteltherapie, Band 1","first-page":"1","article-title":"Chemotherapie bakterieller Infektionen","author":"Domagk","year":"1940"},{"issue":"Suppl. S1","key":"10.1016\/j.ijantimicag.2008.07.017_bib3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1093\/jac\/dkf811","article-title":"Antimicrobial resistance amongst isolates of Streptococcus pyogenes and Staphylococcus aureus in the PROTEKT antimicrobial surveillance programme during 1999\u20132000","volume":"50","author":"Cant\u00f3n","year":"2002","journal-title":"J Antimicrob Chemother"},{"issue":"Suppl. S1","key":"10.1016\/j.ijantimicag.2008.07.017_bib4","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1093\/jac\/dkf808","article-title":"Increasing prevalence of antimicrobial resistance among isolates of Streptococcus pneumoniae from the PROTEKT surveillance study, and comparative in vitro activity of the ketolide telithromycin","volume":"50","author":"Felmingham","year":"2002","journal-title":"J Antimicrob Chemother"},{"issue":"Suppl. S1","key":"10.1016\/j.ijantimicag.2008.07.017_bib5","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1093\/jac\/dkf806","article-title":"Molecular characterisation of macrolide resistance mechanisms among Streptococcus pneumoniae and Streptococcus pyogenes isolated from the PROTEKT 1999\u20132000 study","volume":"50","author":"Farrell","year":"2002","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib6","series-title":"41st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)","article-title":"Molecular characterisation of fluoroquinolone-resistant Streptococcus pneumoniae PROTEKT 2000 isolates from Hong Kong","author":"Morrissey","year":"2001"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib7","unstructured":"Deutsches Institut f\u00fcr Normug e.V. (DIN). Medizinische Mikrobiologie \u2013 Empfindlichkeitspr\u00fcfung von mikrobiellen Krankheitserregern gegen Chemotherapeutika \u2013 Teil 4: Bewertungsstufen f\u00fcr die minimale Hemmkonzentration \u2013 MHK-Grenzwerte von antibakteriellen Wirkstoffen. DIN 58940-4; August 2005. Berlin, Germany: Beuth Verlag GmbH. http:\/\/www.din.de\/cmd?level=tpl-home&contextid=din [accessed 3 July 2008]."},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib8","unstructured":"European Committee on Antimicrobial Susceptibility Testing (EUCAST). Clinical breakpoints. http:\/\/www.srga.org\/eucastwt\/MICTAB [accessed 3 July 2008]."},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib9","series-title":"Performance standards for antimicrobial susceptibility testing. Tenth informational supplement (aerobic dilution)","author":"National Committee for Clinical Laboratory Standards","year":"2000"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib10","doi-asserted-by":"crossref","first-page":"2864","DOI":"10.1128\/JCM.39.8.2864-2872.2001","article-title":"Characterization of clinical isolates of Klebsiella pneumoniae from 19 laboratories using the National Committee for Clinical Laboratory Standards extended-spectrum \u03b2-lactamase detection methods","volume":"39","author":"Steward","year":"2001","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib11","first-page":"97","volume":"14","author":"H\u00f6ffken","year":"2005","journal-title":"Chemother J"},{"issue":"Suppl. A","key":"10.1016\/j.ijantimicag.2008.07.017_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jac\/38.suppl_A.1","article-title":"A multicentre collaborative study of the antimicrobial susceptibility of community-acquired, lower respiratory tract pathogens 1992-1993: the Alexander Project","volume":"38","author":"Felmingham","year":"1996","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib13","unstructured":"White L, Reeves D.S., editors. PROTEKT: an innovative surveillance programme for RTI pathogens. J Antimicrob Chemother 2002;50(Suppl. S1):1\u201370."},{"issue":"Suppl. 2","key":"10.1016\/j.ijantimicag.2008.07.017_bib14","doi-asserted-by":"crossref","first-page":"S81","DOI":"10.1086\/320181","article-title":"Worldwide prevalence of antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis in the SENTRY Antimicrobial Surveillance Program, 1997\u20131999","volume":"32","author":"Hoban","year":"2001","journal-title":"Clin Infect Dis"},{"issue":"Suppl. S2","key":"10.1016\/j.ijantimicag.2008.07.017_bib15","doi-asserted-by":"crossref","first-page":"ii3","DOI":"10.1093\/jac\/dki297","article-title":"The Alexander Project: the benefits from a decade of surveillance","volume":"56","author":"Felmingham","year":"2005","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib16","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1128\/JCM.39.3.1187-1189.2001","article-title":"Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients with respiratory tract infections in Germany from 1998 to 1999: results of a national surveillance study","volume":"39","author":"Reinert","year":"2001","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib17","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1128\/AAC.50.4.1561-1563.2006","article-title":"Active Bacterial Core Surveillance Team, Prevalence of first-step mutants among levofloxacin-susceptible invasive isolates of Streptococcus pneumoniae in the United States","volume":"50","author":"Pletz","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib18","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0732-8893(00)00128-0","article-title":"Benchmarking the in vitro activity of moxifloxacin against recent isolates of Streptococcus pneumoniae, Moraxella catarrhalis, and Haemophilus influenzae. A European multi-centre study","volume":"37","author":"Jones","year":"2000","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib19","doi-asserted-by":"crossref","first-page":"2903","DOI":"10.1128\/AAC.49.7.2903-2913.2005","article-title":"Antimicrobial susceptibility of Streptococcus pneumoniae in eight European countries from 2001 to 2003","volume":"49","author":"Reinert","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib20","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1378\/chest.113.6.1542","article-title":"Infective exacerbations of chronic bronchitis: relation between bacteriologic etiology and lung function","volume":"113","author":"Eller","year":"1998","journal-title":"Chest"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib21","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1093\/jac\/48.3.375","article-title":"Selection of high-level oxacillin resistance in heteroresistant Staphylococcus aureus by fluoroquinolone exposure","volume":"48","author":"Venezia","year":"2001","journal-title":"J Antimicrob Chemother"},{"issue":"Suppl. 1","key":"10.1016\/j.ijantimicag.2008.07.017_bib22","doi-asserted-by":"crossref","first-page":"S16","DOI":"10.1086\/319371","article-title":"Comparative in vitro and in vivo activity of the C-8 methoxy quinolone moxifloxacin and the C-8 chlorine quinolone BAY y3118","volume":"32","author":"Dalhoff","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib23","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1093\/jac\/dkh424","article-title":"Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum \u03b2-lactamases in the UK","volume":"54","author":"Woodford","year":"2004","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib24","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1093\/jac\/dki166","article-title":"Emergence of Enterobacteriaceae producing extended-spectrum \u03b2-lactamases (ESBLs) in the community","volume":"56","author":"Pitout","year":"2005","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2008.07.017_bib25","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1093\/jac\/dki239","article-title":"CTX-M: changing the face of ESBLs in the UK","volume":"56","author":"Livermore","year":"2005","journal-title":"J Antimicrob Chemother"}],"container-title":["International Journal of Antimicrobial Agents"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0924857908003269?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0924857908003269?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,25]],"date-time":"2018-12-25T09:55:22Z","timestamp":1545731722000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0924857908003269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S0924857908003269"],"URL":"https:\/\/doi.org\/10.1016\/j.ijantimicag.2008.07.017","relation":{},"ISSN":["0924-8579"],"issn-type":[{"value":"0924-8579","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}