{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T18:32:16Z","timestamp":1771871536199,"version":"3.50.1"},"reference-count":15,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Antimicrobial Agents"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1016\/j.ijantimicag.2011.07.011","type":"journal-article","created":{"date-parts":[[2011,9,15]],"date-time":"2011-09-15T22:40:28Z","timestamp":1316126428000},"page":"530-533","source":"Crossref","is-referenced-by-count":7,"title":["Bioactivity of WLBU2 peptide antibiotic in combination with bioerodible polymer"],"prefix":"10.1016","volume":"38","author":[{"given":"J.R.","family":"McClanahan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Peyyala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Mahajan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.C.","family":"Montelaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.F.","family":"Novak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.A.","family":"Puleo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0005","first-page":"555","article-title":"The short-term effect of apically repositioned flap surgery on the composition of the subgingival microbiota","volume":"19","author":"Levy","year":"1999","journal-title":"Int J Periodontics Restorative Dent"},{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0010","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1034\/j.1600-0757.2002.280106.x","article-title":"Systemic antibiotics in the treatment of periodontal disease","volume":"28","author":"Slots","year":"2002","journal-title":"Periodontol 2000"},{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0015","doi-asserted-by":"crossref","first-page":"8856","DOI":"10.1073\/pnas.97.16.8856","article-title":"The role of antimicrobial peptides in animal defenses","volume":"97","author":"Hancock","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0020","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1128\/AAC.49.1.316-322.2005","article-title":"De novo generation of cationic antimicrobial peptides: influence of length and tryptophan substitution on antimicrobial activity","volume":"49","author":"Deslouches","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0025","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1128\/AAC.00924-06","article-title":"Efficacy of the de novo-derived antimicrobial peptide WLBU2 against oral bacteria","volume":"51","author":"Novak","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0030","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1109\/MEMB.2003.1256270","article-title":"Association polymers for modulated release of bioactive proteins","volume":"22","author":"Raiche","year":"2003","journal-title":"IEEE Eng Med Biol Mag"},{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0035","doi-asserted-by":"crossref","first-page":"3591","DOI":"10.1016\/j.biomaterials.2008.05.011","article-title":"Alternating release of different bioactive molecules from a complexation polymer system","volume":"29","author":"Jeon","year":"2008","journal-title":"Biomaterials"},{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0040","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1093\/jac\/45.5.713","article-title":"In vitro activity of a cellulose acetate phthalate topical cream against organisms associated with bacterial vaginosis","volume":"45","author":"Neurath","year":"2000","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0045","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1471-2334-1-17","article-title":"Cellulose acetate phthalate, a common pharmaceutical excipient, inactivates HIV-1 and blocks the coreceptor binding site on the virus envelope glycoprotein gp120","volume":"1","author":"Neurath","year":"2001","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0050","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1111\/j.1600-0463.2010.02667.x","article-title":"Modulation of exogenous antibiotic activity by host cathelicidin LL-37","volume":"118","author":"Leszczynska","year":"2010","journal-title":"APMIS"},{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0055","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1023\/A:1016213405081","article-title":"Mucoadhesive polymers in peroral peptide drug delivery. II. Carbomer and polycarbophil are potent inhibitors of the intestinal proteolytic enzyme trypsin","volume":"12","author":"Luessen","year":"1995","journal-title":"Pharm Res"},{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0060","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.colsurfb.2009.08.026","article-title":"Binding, inactivation, and adhesion forces between antimicrobial peptide cecropin P1 and pathogenic E. coli","volume":"75","author":"Strauss","year":"2010","journal-title":"Colloids Surf B Biointerfaces"},{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0065","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1128\/AAC.01254-08","article-title":"Immobilization reduces the activity of surface-bound cationic antimicrobial peptides with no influence upon the activity spectrum","volume":"53","author":"Bagheri","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0070","first-page":"307","article-title":"The development of stable protein formulations: a close look at protein aggregation, deamidation, and oxidation","volume":"10","author":"Cleland","year":"1993","journal-title":"Crit Rev Ther Drug Carrier Syst"},{"key":"10.1016\/j.ijantimicag.2011.07.011_bib0075","doi-asserted-by":"crossref","first-page":"361","DOI":"10.2174\/1389201023378229","article-title":"The stability factor: importance in formulation development","volume":"3","author":"Krishnamurthy","year":"2002","journal-title":"Curr Pharm Biotechnol"}],"container-title":["International Journal of Antimicrobial Agents"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0924857911003207?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0924857911003207?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T02:58:53Z","timestamp":1543546733000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0924857911003207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["S0924857911003207"],"URL":"https:\/\/doi.org\/10.1016\/j.ijantimicag.2011.07.011","relation":{},"ISSN":["0924-8579"],"issn-type":[{"value":"0924-8579","type":"print"}],"subject":[],"published":{"date-parts":[[2011,12]]}}}