{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T10:35:17Z","timestamp":1778754917585,"version":"3.51.4"},"reference-count":161,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["ijaaonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Antimicrobial Agents"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1016\/j.ijantimicag.2014.04.008","type":"journal-article","created":{"date-parts":[[2014,5,17]],"date-time":"2014-05-17T15:46:52Z","timestamp":1400341612000},"page":"96-104","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"title":["Clinical utility of caspofungin eye drops in fungal keratitis"],"prefix":"10.1016","volume":"44","author":[{"given":"Chin Fen","family":"Neoh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9528-7005","authenticated-orcid":false,"given":"Mark","family":"Daniell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon C.-A.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kay","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David C.M.","family":"Kong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0005","first-page":"214","article-title":"Corneal blindness: a global perspective","volume":"79","author":"Whitcher","year":"2001","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0010","first-page":"844","article-title":"Global data on visual impairment in the year 2002","volume":"82","author":"Resnikoff","year":"2004","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0015","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1097\/00055735-200408000-00008","article-title":"Fungal keratitis","volume":"15","author":"Srinivasan","year":"2004","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0020","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/QCO.0b013e328017f878","article-title":"Infectious keratitis","volume":"20","author":"Thomas","year":"2007","journal-title":"Curr Opin Infect Dis"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0025","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD004241.pub2","article-title":"Medical interventions for fungal keratitis","volume":"1","author":"FlorCruz","year":"2008","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0030","first-page":"111","article-title":"Therapeutic keratoplasty for infectious keratitis: a review of the literature","volume":"28","author":"Sony","year":"2002","journal-title":"CLAO J"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0035","first-page":"235","article-title":"Fungal keratitis at the University of Minnesota: 1971\u20131981","volume":"80","author":"Doughman","year":"1982","journal-title":"Trans Am Ophthalmol Soc"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0040","series-title":"Infectious diseases of the eye","first-page":"184","article-title":"Keratomycosis in a New England referral center: spectrum of pathogenic organisms and predisposing factors","author":"Kelly","year":"1994"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0045","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/00003226-200305000-00004","article-title":"Advanced Fusarium keratitis progressing to endophthalmitis","volume":"22","author":"Dursun","year":"2003","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0050","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1136\/bjophthalmol-2011-301148","article-title":"The challenge of fungal keratitis","volume":"95","author":"Said","year":"2011","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0055","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1136\/bjo.2009.169607","article-title":"Geographic variations in microbial keratitis: an analysis of the peer-reviewed literature","volume":"95","author":"Shah","year":"2011","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0060","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1080\/09286580601001347","article-title":"Microbial keratitis in South India: influence of risk factors, climate, and geographical variation","volume":"14","author":"Bharathi","year":"2007","journal-title":"Ophthalmic Epidemiol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0065","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0035-9203(01)90180-4","article-title":"Microbial keratitis in Hong Kong: relationship to climate, environment and contact-lens disinfection","volume":"95","author":"Houang","year":"2001","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0070","doi-asserted-by":"crossref","first-page":"17","DOI":"10.4103\/0301-4738.15280","article-title":"Epidemiological and microbiological diagnosis of suppurative keratitis in Gangetic West Bengal, Eastern India","volume":"53","author":"Basak","year":"2005","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0075","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/j.1442-9071.2007.01417.x","article-title":"Demographic pattern, predisposing factors and management of ulcerative keratitis: evaluation of one thousand unilateral cases at a tertiary care centre","volume":"35","author":"Panda","year":"2007","journal-title":"Clin Experiment Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0080","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1136\/bjo.81.11.965","article-title":"Epidemiology and aetiological diagnosis of corneal ulceration in Madurai, South India","volume":"81","author":"Srinivasan","year":"1997","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0085","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1136\/bjo.86.11.1211","article-title":"Aetiology of suppurative corneal ulcers in Ghana and South India, and epidemiology of fungal keratitis","volume":"86","author":"Leck","year":"2002","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0090","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1136\/bjo.79.11.1024","article-title":"Causes of suppurative keratitis in Ghana","volume":"79","author":"Hagan","year":"1995","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0095","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1159\/000084273","article-title":"Laboratory diagnosis in ulcerative keratitis","volume":"37","author":"Khanal","year":"2005","journal-title":"Ophthalmic Res"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0100","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1136\/bjo.2006.094706","article-title":"Corneal ulceration in South East Asia. II. A strategy for the prevention of fungal keratitis at the village level in Burma","volume":"90","author":"Maung","year":"2006","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0105","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1136\/bjo.2007.123208","article-title":"Initial therapy for suppurative microbial keratitis in Iraq","volume":"91","author":"Al-Shakarchi","year":"2007","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0110","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1442-9071.1994.tb00775.x","article-title":"Suppurative corneal ulceration in Bangladesh. A study of 142 cases examining the microbiological diagnosis, clinical and epidemiological features of bacterial and fungal keratitis","volume":"22","author":"Dunlop","year":"1994","journal-title":"Aust N Z J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0115","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1007\/s00417-003-0808-4","article-title":"Epidemiological characteristics of microbiological results on patients with infectious corneal ulcers: a 13-year survey in Paraguay","volume":"242","author":"Laspina","year":"2004","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0120","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1097\/ICO.0b013e31815ca0bb","article-title":"Predisposing factors and etiologic diagnosis of ulcerative keratitis","volume":"27","author":"Sirikul","year":"2008","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0125","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s10792-007-9069-2","article-title":"Microbial keratitis in West Anatolia, Turkey: a retrospective review","volume":"27","author":"Yilmaz","year":"2007","journal-title":"Int Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0130","series-title":"IVth Congress of the European Society of Ophthalmology","first-page":"395","article-title":"Suppurative keratitis in London","author":"Coster","year":"1981"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0135","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1111\/j.1442-9071.2006.01405.x","article-title":"Fungal keratitis in Melbourne","volume":"35","author":"Bhartiya","year":"2007","journal-title":"Clin Experiment Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0140","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1097\/ICO.0b013e318156caf2","article-title":"Risk factors and causative organisms in microbial keratitis","volume":"27","author":"Green","year":"2008","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0145","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1001\/archopht.1982.01030030079005","article-title":"Ulcerative keratitis. Survey of 30 years\u2019 laboratory experience","volume":"100","author":"Asbell","year":"1982","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0150","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/S0002-9394(14)75075-5","article-title":"Spectrum of microbial keratitis in South Florida","volume":"90","author":"Liesegang","year":"1980","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0155","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1038\/sj.eye.6700557","article-title":"Fungal infections of the cornea","volume":"17","author":"Thomas","year":"2003","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0160","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1439-0507.1991.tb00653.x","article-title":"Mycotic keratitis in Paraguay","volume":"34","author":"Mino de Kaspar","year":"1991","journal-title":"Mycoses"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0165","first-page":"275","article-title":"Risk factors and clinical outcomes between fungal and bacterial keratitis: a comparative study","volume":"23","author":"Wong","year":"1997","journal-title":"CLAO J"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0170","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1097\/00003226-200208000-00004","article-title":"The epidemiological features and laboratory results of fungal keratitis: a 10-year review at a referral eye care center in South India","volume":"21","author":"Gopinathan","year":"2002","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0175","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S0002-9394(14)76903-X","article-title":"Epidemiologic characteristics, predisposing factors, and etiologic diagnosis of corneal ulceration in Nepal","volume":"111","author":"Upadhyay","year":"1991","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0180","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0161-6420(94)31225-5","article-title":"The changing spectrum of fungal keratitis in south Florida","volume":"101","author":"Rosa","year":"1994","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0185","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1016\/j.ophtha.2006.05.035","article-title":"Spectrum of fungal keratitis in North China","volume":"113","author":"Xie","year":"2006","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0190","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1111\/j.1442-9071.2008.01879.x","article-title":"Fungal keratitis in far North Queensland, Australia","volume":"36","author":"Thew","year":"2008","journal-title":"Clin Experiment Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0195","doi-asserted-by":"crossref","first-page":"e215","DOI":"10.1111\/j.1755-3768.2010.01946.x","article-title":"Fungal keratitis in France","volume":"89","author":"Gaujoux","year":"2011","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0200","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1097\/ICO.0b013e318191695b","article-title":"Fungal keratitis: changing pathogens and risk factors","volume":"28","author":"Jurkunas","year":"2009","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0205","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1097\/ICO.0b013e318142bff3","article-title":"Fungal keratitis in London: microbiological and clinical evaluation","volume":"26","author":"Galarreta","year":"2007","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0210","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1097\/00003226-200005000-00010","article-title":"Spectrum of fungal keratitis at Wills Eye Hospital, Philadelphia, Pennsylvania","volume":"19","author":"Tanure","year":"2000","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0215","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1038\/eye.2008.298","article-title":"Fungal keratitis in the United Kingdom 2003\u20132005","volume":"23","author":"Tuft","year":"2009","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0220","series-title":"Ocular infection: investigation and treatment in practice","first-page":"21","article-title":"Tropical ophthalmomycoses","author":"Thomas","year":"1998"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0225","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1001\/archopht.1990.01070090108050","article-title":"Ocular uptake of fluconazole following oral administration","volume":"108","author":"O\u2019Day","year":"1990","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0230","doi-asserted-by":"crossref","first-page":"6393","DOI":"10.1074\/jbc.M707821200","article-title":"Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane","volume":"283","author":"te Welscher","year":"2008","journal-title":"J Biol Chem"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0235","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1001\/archopht.1972.01000030149004","article-title":"Fusarium solani keratitis treated with natamycin (pimaricin): eighteen consecutive cases","volume":"88","author":"Jones","year":"1972","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0240","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1097\/00007611-197108000-00008","article-title":"Clinical experience with pimaricin therapy in fungal keratitis","volume":"64","author":"Newmark","year":"1971","journal-title":"South Med J"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0245","first-page":"249","article-title":"A comparative evaluation of nystatin, amphotericin B and miconazole in keratomycosis","volume":"30","author":"Reddy","year":"1982","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0250","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1089\/jop.2010.0069","article-title":"Successful treatment of Pseudallescheria boydii keratitis with topical natamycin as monotherapy","volume":"26","author":"Wong","year":"2010","journal-title":"J Ocul Pharmacol Ther"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0255","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.ajo.2008.04.019","article-title":"Antifungal susceptibility for common pathogens of fungal keratitis in Shandong Province, China","volume":"146","author":"Xie","year":"2008","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0260","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1097\/ICO.0b013e318199fa77","article-title":"Practice patterns in the management of fungal corneal ulcers","volume":"28","author":"Loh","year":"2009","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0265","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1136\/bjo.2007.136515","article-title":"Voriconazole in the treatment of fungal eye infections: a review of current literature","volume":"92","author":"Hariprasad","year":"2008","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0270","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0896-1549(05)70147-4","article-title":"Therapy of ocular fungal infections","volume":"12","author":"O\u2019Brien","year":"1999","journal-title":"Ophthalmol Clin North Am"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0275","doi-asserted-by":"crossref","first-page":"512","DOI":"10.4103\/0301-4738.86328","article-title":"Natamycin in the treatment of keratomycosis: correlation of treatment outcome and in vitro susceptibility of fungal isolates","volume":"59","author":"Pradhan","year":"2011","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0280","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1128\/AAC.34.2.183","article-title":"Amphotericin B: current understanding of mechanisms of action","volume":"34","author":"Brajtburg","year":"1990","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0285","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1001\/archopht.123.12.1721","article-title":"Intracorneal injection of amphothericin B for recurrent fungal keratitis and endophthalmitis","volume":"123","author":"Garcia-Valenzuela","year":"2005","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0290","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1097\/ICO.0b013e318030767e","article-title":"Efficacy of intracameral amphotericin B injection in the management of refractory keratomycosis and endophthalmitis","volume":"26","author":"Yilmaz","year":"2007","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0295","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1097\/ICO.0b013e31806c791e","article-title":"Therapeutic effect of intracameral amphotericin B injection in the treatment of fungal keratitis","volume":"26","author":"Yoon","year":"2007","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0300","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1097\/00003226-200110000-00009","article-title":"Intracameral amphotericin B: initial experience in severe keratomycosis","volume":"20","author":"Kaushik","year":"2001","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0305","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1097\/00003226-200210000-00004","article-title":"Intracameral amphotericin B injection in the management of deep keratomycosis","volume":"21","author":"Kuriakose","year":"2002","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0310","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1097\/ICO.0b013e3181fb826d","article-title":"Treatment of severe fungal keratitis with subconjunctival amphotericin B","volume":"30","author":"Carrasco","year":"2011","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0315","first-page":"252","article-title":"The use of collagen shields impregnated with amphotericin B to treat Aspergillus keratomycosis","volume":"21","author":"Mendicute","year":"1995","journal-title":"CLAO J"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0320","doi-asserted-by":"crossref","first-page":"877","DOI":"10.3109\/02713688609029240","article-title":"Corneal penetration of topical amphotericin B and natamycin","volume":"5","author":"O\u2019Day","year":"1986","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0325","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1093\/jac\/33.2.203","article-title":"Administering amphotericin B \u2013 a practical approach","volume":"33","author":"Khoo","year":"1994","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0330","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/0002-9343(73)90207-6","article-title":"5-Fluorocytosine treatment of meningeal and pulmonary aspergillosis","volume":"55","author":"Atkinson","year":"1973","journal-title":"Am J Med"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0335","first-page":"566","article-title":"Chemotherapeutic activity of 5-flourocytosine","volume":"3","author":"Gruneberg","year":"1964","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0340","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1159\/000307726","article-title":"Treatment of external ocular Candida infections with 5-fluorocytosine","volume":"172","author":"Romano","year":"1976","journal-title":"Ophthalmologica"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0345","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1128\/CMR.12.4.501","article-title":"Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance","volume":"12","author":"Ghannoum","year":"1999","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0350","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/j.1439-0507.2012.02194.x","article-title":"Epidemiology of Aspergillus keratitis at a tertiary care eye hospital in South India and antifungal susceptibilities of the causative agents","volume":"56","author":"Manikandan","year":"2013","journal-title":"Mycoses"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0355","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1159\/000050885","article-title":"Use of topical clotrimazole in human keratomycosis","volume":"215","author":"Mselle","year":"2001","journal-title":"Ophthalmologica"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0360","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/0002-9394(86)90953-0","article-title":"Miconazole and ketoconazole as a satisfactory first-line treatment for keratomycosis","volume":"101","author":"Fitzsimons","year":"1986","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0365","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/0002-9394(81)90063-5","article-title":"Miconazole therapy for keratomycosis","volume":"91","author":"Foster","year":"1981","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0370","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/0002-9394(84)90126-0","article-title":"The effects of intravenous miconazole on fungal keratitis","volume":"98","author":"Ishibashi","year":"1984","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0375","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1111\/j.1755-3768.1991.tb04862.x","article-title":"Pseudallescheria boydii keratitis","volume":"69","author":"Ruben","year":"1991","journal-title":"Acta Ophthalmol (Copenh)"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0380","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1001\/archopht.1979.01020020271017","article-title":"Intraocular penetration of miconazole in rabbits","volume":"97","author":"Foster","year":"1979","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0385","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1097\/ICO.0b013e318142bff3","article-title":"Fungal keratitis in London: microbiological and clinical evaluation","volume":"26","author":"Galarreta","year":"2007","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0390","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1111\/myc.12062","article-title":"Fusarium keratitis in South India: causative agents, their antifungal susceptibilities and a rapid identification method for the Fusarium solani species complex","volume":"56","author":"Homa","year":"2013","journal-title":"Mycoses"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0395","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1136\/bjo.87.10.1235","article-title":"A randomised clinical trial comparing 2% econazole and 5% natamycin for the treatment of fungal keratitis","volume":"87","author":"Prajna","year":"2003","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0400","first-page":"149","article-title":"A comparative study of anti-fungal drugs in mycotic corneal ulcer","volume":"35","author":"Mahashabde","year":"1987","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0405","first-page":"1019","article-title":"Treatment of fungal corneal ulcers with econazole","volume":"31","author":"Arora","year":"1983","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0410","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/S0002-9394(14)78302-3","article-title":"Oral ketoconazole therapy for keratomycosis","volume":"95","author":"Ishibashi","year":"1983","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0415","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0002-9394(85)90795-0","article-title":"Topical ketoconazole for fungal keratitis","volume":"100","author":"Torres","year":"1985","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0420","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1097\/00003226-199207000-00011","article-title":"Intraocular penetration of ketoconazole in rabbits","volume":"11","author":"Hemady","year":"1992","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0425","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1001\/archopht.1981.03930011081019","article-title":"Ocular toxicity of topical antifungal agents","volume":"99","author":"Foster","year":"1981","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0430","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1097\/00003226-199711000-00019","article-title":"Fluconazole in filamentous fungal keratitis","volume":"16","author":"Rao","year":"1997","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0435","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1097\/00003226-199701000-00012","article-title":"Ocular penetration and pharmacokinetics of topical fluconazole","volume":"16","author":"Yee","year":"1997","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0440","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1006\/exer.2000.0936","article-title":"Penetration of topical fluconazole into human aqueous humor","volume":"72","author":"Abbasoglu","year":"2001","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0445","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1097\/ICO.0b013e318221cf12","article-title":"A new long-acting liposomal topical antifungal formula: human clinical study","volume":"31","author":"Abdel-Rhaman","year":"2012","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0450","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.ajo.2005.12.025","article-title":"Severe fungal keratitis treated with subconjunctival fluconazole","volume":"141","author":"Dev","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0455","first-page":"309","article-title":"Efficacy of fluconazole subconjunctival injection as adjunctive therapy for severe recalcitrant fungal corneal ulcer","volume":"91","author":"Isipradit","year":"2008","journal-title":"J Med Assoc Thai"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0460","doi-asserted-by":"crossref","first-page":"193","DOI":"10.3109\/15569521003801454","article-title":"Assessment safety and efficacy of a combination therapy of topical amphotericin B and subconjunctival fluconazole for the treatment of fungal keratitis","volume":"29","author":"Mahdy","year":"2010","journal-title":"Cutan Ocul Toxicol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0465","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1128\/AAC.31.1.6","article-title":"Penetration of new azole compounds into the eye and efficacy in experimental Candida endophthalmitis","volume":"31","author":"Savani","year":"1987","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0470","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1097\/01.ico.0000151539.92865.3e","article-title":"Comparison of topical itraconazole 1% with topical natamycin 5% for the treatment of filamentous fungal keratitis","volume":"24","author":"Kalavathy","year":"2005","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0475","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1439-0507.1988.tb03986.x","article-title":"Oral itraconazole therapy for mycotic keratitis","volume":"31","author":"Thomas","year":"1988","journal-title":"Mycoses"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0480","first-page":"157","article-title":"Itraconazole therapy for fungal keratitis","volume":"35","author":"Rajasekaran","year":"1987","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0485","series-title":"Aspergillus and aspergillosis","first-page":"267","article-title":"Treatment of Aspergillus keratitis with imidazoles and related compounds","author":"Thomas","year":"1988"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0490","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.ajo.2003.11.078","article-title":"In vitro investigation of voriconazole susceptibility for keratitis and endophthalmitis fungal pathogens","volume":"137","author":"Marangon","year":"2004","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0495","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ajo.2008.02.023","article-title":"Evaluation of intrastromal injection of voriconazole as a therapeutic adjunctive for the management of deep recalcitrant fungal keratitis","volume":"146","author":"Prakash","year":"2008","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0500","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1097\/ICO.0b013e3182100993","article-title":"The effects of intrastromal voriconazole injection and topical voriconazole in the treatment of recalcitrant Fusarium keratitis","volume":"30","author":"Siatiri","year":"2011","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0505","doi-asserted-by":"crossref","first-page":"265","DOI":"10.4103\/0974-9233.95271","article-title":"Combination of intracameral and intrastromal voriconazole in the treatment of recalcitrant Acremonium fungal keratitis","volume":"19","author":"Haddad","year":"2012","journal-title":"Middle East Afr J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0510","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1128\/AAC.00762-06","article-title":"Voriconazole concentration in human aqueous humor and plasma during topical or combined topical and systemic administration for fungal keratitis","volume":"51","author":"Thiel","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0515","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1001\/archophthalmol.2007.8","article-title":"Aqueous and vitreous concentrations following topical administration of 1% voriconazole in humans","volume":"126","author":"Vemulakonda","year":"2008","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0520","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1001\/archophthalmol.2007.71","article-title":"Penetration of voriconazole, 1%, eyedrops into human aqueous humor: a prospective open-label study","volume":"126","author":"Lau","year":"2008","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0525","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1111\/j.1442-9071.2008.01911.x","article-title":"Penetration of 1% voriconazole eye drops into human vitreous humour: a prospective, open-label study","volume":"37","author":"Lau","year":"2009","journal-title":"Clin Experiment Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0530","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1001\/archopht.122.1.42","article-title":"Determination of vitreous, aqueous, and plasma concentration of orally administered voriconazole in humans","volume":"122","author":"Hariprasad","year":"2004","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0535","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1136\/bjo.86.7.829-a","article-title":"Ocular and systemic posaconazole (SCH-56592) treatment of invasive Fusarium solani keratitis and endophthalmitis","volume":"86","author":"Sponsel","year":"2002","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0540","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.ajo.2006.10.048","article-title":"Successful treatment of resistant ocular fusariosis with posaconazole (SCH-56592)","volume":"143","author":"Tu","year":"2007","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0545","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1097\/ICO.0b013e31815e9298","article-title":"Atypical fungal sclerokeratitis","volume":"27","author":"Amiel","year":"2008","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0550","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1097\/ICO.0b013e3180de4953","article-title":"Recalcitrant Beauveria bassiana keratitis: confocal microscopy findings and treatment with posaconazole (Noxafil)","volume":"26","author":"Tu","year":"2007","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0555","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1177\/106002809703100412","article-title":"Oral terbinafine: a new antifungal agent","volume":"31","author":"Abdel-Rahman","year":"1997","journal-title":"Ann Pharmacother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0560","doi-asserted-by":"crossref","first-page":"2723","DOI":"10.1517\/14656560903307462","article-title":"Terbinafine: a pharmacological and clinical review","volume":"10","author":"Krishnan-Natesan","year":"2009","journal-title":"Expert Opin Pharmacother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0565","doi-asserted-by":"crossref","first-page":"196","DOI":"10.4103\/0301-4738.116463","article-title":"Bacterial and fungal keratitis in Upper Egypt: in vitro screening of enzymes, toxins and antifungal activity","volume":"62","author":"Gharamah","year":"2014","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0570","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.ajo.2008.06.008","article-title":"In vitro evaluation of combination antifungal activity against Fusarium species isolated from ocular tissues of keratomycosis patients","volume":"146","author":"Li","year":"2008","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0575","first-page":"1884","article-title":"Effect of topical application of terbinafine on fungal keratitis","volume":"122","author":"Liang","year":"2009","journal-title":"Chin Med J (Engl)"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0580","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1463-5224.2010.00841.x","article-title":"Aqueous humor and plasma concentrations of a compounded 0.2% solution of terbinafine following topical ocular administration to normal equine eyes","volume":"14","author":"Clode","year":"2011","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0585","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1517\/14656566.5.4.865","article-title":"Antifungal therapy for keratomycoses","volume":"5","author":"Ganegoda","year":"2004","journal-title":"Expert Opin Pharmacother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0590","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1128\/CMR.16.4.730-797.2003","article-title":"Current perspectives on ophthalmic mycoses","volume":"16","author":"Thomas","year":"2003","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0595","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1080\/02681219780000961","article-title":"Lipopeptide inhibitors of fungal glucan synthase","volume":"35","author":"Kurtz","year":"1997","journal-title":"J Med Vet Mycol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0600","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1136\/bjo.2010.191734","article-title":"The comparison of solitary topical micafungin or fluconazole application in the treatment of Candida fungal keratitis","volume":"95","author":"Matsumoto","year":"2011","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0605","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1097\/01.ico.0000154390.28254.54","article-title":"Successful topical application of a new antifungal agent, micafungin, in the treatment of refractory fungal corneal ulcers: report of three cases and literature review","volume":"24","author":"Matsumoto","year":"2005","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0610","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1097\/ICO.0b013e31802cd8a8","article-title":"Comparison of micafungin and fluconazole for experimental Candida keratitis in rabbits","volume":"26","author":"Hiraoka","year":"2007","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0615","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1001\/archopht.125.6.789","article-title":"Antimicrobial susceptibility of Fusarium, Aspergillus, and other filamentous fungi isolated from keratitis","volume":"125","author":"Lalitha","year":"2007","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0620","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.diagmicrobio.2008.07.003","article-title":"Determination of in vitro susceptibility of ocular Fusarium spp. isolates from keratitis cases and comparison of Clinical and Laboratory Standards Institute M38-A2 and E test methods","volume":"62","author":"Iqbal","year":"2008","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0625","doi-asserted-by":"crossref","first-page":"130","DOI":"10.3109\/13693786.2011.584328","article-title":"Antifungal susceptibility of ocular fungal pathogens recovered from around the world against itraconazole, voriconazole, amphotericin B, and caspofungin","volume":"50","author":"Ozdemir","year":"2012","journal-title":"Med Mycol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0630","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1097\/ICO.0b013e31818225f8","article-title":"Alternaria keratitis: clinical presentation and resolution with topical fluconazole or intrastromal voriconazole and topical caspofungin","volume":"28","author":"Tu","year":"2009","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0635","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1159\/000187627","article-title":"Aqueous humor concentrations of topically administered caspofungin in rabbits","volume":"41","author":"Vorwerk","year":"2009","journal-title":"Ophthalmic Res"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0640","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1097\/00003226-198706040-00002","article-title":"Selection of appropriate antifungal therapy","volume":"6","author":"O\u2019Day","year":"1987","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0645","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1136\/bjo.2010.192815","article-title":"Evaluation of intrastromal voriconazole injection in recalcitrant deep fungal keratitis: case series","volume":"95","author":"Sharma","year":"2011","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0650","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1097\/ICO.0b013e318233f0a8","article-title":"Intracameral and topical voriconazole for fungal corneal endoexudates","volume":"31","author":"Mittal","year":"2012","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0655","doi-asserted-by":"crossref","first-page":"3153","DOI":"10.1128\/AAC.01700-08","article-title":"Prospective open-label study of the administration of two-percent voriconazole eye drops","volume":"53","author":"Al-Badriyeh","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0660","doi-asserted-by":"crossref","first-page":"e110","DOI":"10.1086\/430062","article-title":"Successful treatment of Fusarium keratitis with cornea transplantation and topical and systemic voriconazole","volume":"40","author":"Klont","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0665","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/1469-0691.12126","article-title":"Mycotic keratitis: epidemiology, diagnosis and management","volume":"19","author":"Thomas","year":"2013","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0670","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.ajo.2004.08.077","article-title":"Management of endogenous fungal endophthalmitis with voriconazole and caspofungin","volume":"139","author":"Breit","year":"2005","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0675","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/1471-2334-7-87","article-title":"Treatment of two postoperative endophthalmitis cases due to Aspergillus flavus and Scopulariopsis spp. with local and systemic antifungal therapy","volume":"7","author":"Aydin","year":"2007","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0680","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.ajo.2005.03.030","article-title":"Successful treatment of Fusarium endophthalmitis with voriconazole and Aspergillus endophthalmitis with voriconazole plus caspofungin","volume":"140","author":"Durand","year":"2005","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0685","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.1086\/431761","article-title":"Subtherapeutic ocular penetration of caspofungin and associated treatment failure in Candida albicans endophthalmitis","volume":"41","author":"Gauthier","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0690","doi-asserted-by":"crossref","first-page":"e46","DOI":"10.1086\/427753","article-title":"Candida glabrata endophthalmitis treated successfully with caspofungin","volume":"40","author":"Sarria","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0695","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1080\/13693780600717161","article-title":"Fungal endophthalmitis caused by Aspergillus ustus in a patient following cataract surgery","volume":"44","author":"Yildiran","year":"2006","journal-title":"Med Mycol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0700","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1093\/jac\/dkp306","article-title":"Intraocular penetration of voriconazole and caspofungin in a patient with fungal endophthalmitis","volume":"64","author":"Spriet","year":"2009","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0705","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1007\/s00417-006-0460-x","article-title":"Ocular penetration of caspofungin in a rabbit uveitis model","volume":"245","author":"Goldblum","year":"2007","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0710","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1080\/13693780500271772","article-title":"Aspergillus flavus scleritis: successful treatment with voriconazole and caspofungin","volume":"43","author":"Howell","year":"2005","journal-title":"Med Mycol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0715","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1080\/00365540600617041","article-title":"Severe Candida albicans panophthalmitis treated with all available and potentially effective antifungal drugs: fluconazole, liposomal amphotericin B, caspofungin, and voriconazole","volume":"38","author":"Manfredi","year":"2006","journal-title":"Scand J Infect Dis"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0720","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/S0140-6736(03)14472-8","article-title":"Echinocandin antifungal drugs","volume":"362","author":"Denning","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0725","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1517\/17425247.3.2.275","article-title":"Ocular drug delivery","volume":"3","author":"Ghate","year":"2006","journal-title":"Expert Opin Drug Deliv"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0730","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1081\/DDC-120003445","article-title":"Ocular preparations: the formulation approach","volume":"28","author":"Kaur","year":"2002","journal-title":"Drug Dev Ind Pharm"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0735","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/j.addr.2006.07.027","article-title":"Challenges and obstacles of ocular pharmacokinetics and drug delivery","volume":"58","author":"Urtti","year":"2006","journal-title":"Adv Drug Deliv Rev"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0740","series-title":"CANCIDAS\u00ae (caspofungin acetate) package insert","author":"Merck & Co. Inc.","year":"2009"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0745","series-title":"CANCIDAS (formerly caspofungin MSD)","author":"Electronic Medicines Compendium","year":"2014"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0750","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1001\/archophthalmol.2010.110","article-title":"Successful topical application of caspofungin in the treatment of fungal keratitis refractory to voriconazole","volume":"128","author":"Hurtado-Sarri\u00f3","year":"2010","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0755","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.1128\/AAC.00060-12","article-title":"Stability of extemporaneously prepared 0.5-percent caspofungin eye drops: a potential cost-savings exercise","volume":"56","author":"Neoh","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0760","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1128\/AAC.01175-10","article-title":"Penetration of topically administered 0.5-percent caspofungin eye drops into human aqueous humor","volume":"55","author":"Neoh","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0765","doi-asserted-by":"crossref","first-page":"4467","DOI":"10.1128\/AAC.00509-10","article-title":"Rapid and sensitive liquid chromatography\/mass spectrometry assay for caspofungin in human aqueous humor","volume":"54","author":"Neoh","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0770","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1128\/AAC.49.4.1359-1363.2005","article-title":"Topical caspofungin for treatment of keratitis caused by Candida albicans in a rabbit model","volume":"49","author":"Goldblum","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0775","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1097\/ICO.0b013e3180553b9d","article-title":"Efficacy of topical caspofungin in experimental Fusarium keratitis","volume":"26","author":"Ozturk","year":"2007","journal-title":"Cornea"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0780","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1001\/archophthalmol.2010.264","article-title":"Recurrent fungal keratitis following penetrating keratoplasty: an unusual source of infection","volume":"128","author":"Gregory","year":"2010","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0785","doi-asserted-by":"crossref","first-page":"e24","DOI":"10.1345\/aph.1P586","article-title":"Treatment of Alternaria keratitis with intrastromal and topical caspofungin in combination with intrastromal, topical, and oral voriconazole","volume":"45","author":"Neoh","year":"2011","journal-title":"Ann Pharmacother"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0790","doi-asserted-by":"crossref","first-page":"e110","DOI":"10.1111\/j.1439-0507.2009.01853.x","article-title":"Intraocular caspofungin: in vitro safety profile for human ocular cells","volume":"54","author":"Kernt","year":"2011","journal-title":"Mycoses"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0795","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1080\/02713680601107157","article-title":"The effects of caspofungin and voriconazole in experimental Candida endophthalmitis","volume":"32","author":"Kusbeci","year":"2007","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0800","doi-asserted-by":"crossref","first-page":"5796","DOI":"10.1167\/iovs.10-5541","article-title":"Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye","volume":"51","author":"Mojumder","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ijantimicag.2014.04.008_bib0805","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1046\/j.1365-2710.1998.00136.x","article-title":"Stability of cefazolin sodium eye drops","volume":"23","author":"How","year":"1998","journal-title":"J Clin Pharm Ther"}],"container-title":["International Journal of Antimicrobial Agents"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0924857914001320?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0924857914001320?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,26]],"date-time":"2024-05-26T19:06:15Z","timestamp":1716750375000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0924857914001320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":161,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["S0924857914001320"],"URL":"https:\/\/doi.org\/10.1016\/j.ijantimicag.2014.04.008","relation":{},"ISSN":["0924-8579"],"issn-type":[{"value":"0924-8579","type":"print"}],"subject":[],"published":{"date-parts":[[2014,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical utility of caspofungin eye drops in fungal keratitis","name":"articletitle","label":"Article Title"},{"value":"International Journal of Antimicrobial Agents","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijantimicag.2014.04.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.","name":"copyright","label":"Copyright"}]}}