{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T14:54:58Z","timestamp":1780930498933,"version":"3.54.1"},"reference-count":15,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","ijaaonline.com","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Antimicrobial Agents"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1016\/j.ijantimicag.2015.03.006","type":"journal-article","created":{"date-parts":[[2015,4,25]],"date-time":"2015-04-25T22:14:33Z","timestamp":1430000073000},"page":"342-345","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Prior in vitro exposure to voriconazole confers resistance to amphotericin B in Aspergillus fumigatus biofilms"],"prefix":"10.1016","volume":"46","author":[{"given":"Ranjith","family":"Rajendran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eilidh","family":"Mowat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon","family":"Ramage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0080","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.3201\/eid1710.110226","article-title":"Clinical implications of azole resistance in Aspergillus fumigatus, The Netherlands, 2007\u20132009","volume":"17","author":"van der Linden","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0085","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S1368-7646(98)80034-4","article-title":"Resistance to amphotericin B: emerging clinical and microbiological patterns","volume":"1","author":"Sterling","year":"1998","journal-title":"Drug Resist Update"},{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0090","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1128\/AAC.01189-10","article-title":"Azole resistance of Aspergillus fumigatus biofilms is partly associated with efflux pump activity","volume":"55","author":"Rajendran","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0095","doi-asserted-by":"crossref","first-page":"e1002257","DOI":"10.1371\/journal.ppat.1002257","article-title":"Hsp90 governs dispersion and drug resistance of fungal biofilms","volume":"7","author":"Robbins","year":"2011","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0100","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1128\/EC.00287-12","article-title":"Extracellular DNA release acts as an antifungal resistance mechanism in mature Aspergillus fumigatus biofilms","volume":"12","author":"Rajendran","year":"2013","journal-title":"Eukaryot Cell"},{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0105","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/S0014-5793(96)01360-9","article-title":"Resistance to fluconazole and cross-resistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol \u03945,6-desaturation","volume":"400","author":"Kelly","year":"1997","journal-title":"FEBS Lett"},{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0110","doi-asserted-by":"crossref","first-page":"2690","DOI":"10.1128\/JCM.36.9.2690-2695.1998","article-title":"Stable phenotypic resistance of Candida species to amphotericin B conferred by preexposure to subinhibitory levels of azoles","volume":"36","author":"Vazquez","year":"1998","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0115","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1093\/jac\/dkq279","article-title":"Azole antifungal resistance in Aspergillus fumigatus: 2008 and 2009","volume":"65","author":"Bueid","year":"2010","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0120","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1038\/nprot.2008.141","article-title":"A simple and reproducible 96-well plate-based method for the formation of fungal biofilms and its application to antifungal susceptibility testing","volume":"3","author":"Pierce","year":"2008","journal-title":"Nat Protoc"},{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0125","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1128\/AAC.01745-13","article-title":"In vitro study of sequential fluconazole and caspofungin treatment against Candida albicans biofilms","volume":"58","author":"Sarkar","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0130","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1128\/EC.4.4.633-638.2005","article-title":"Candida biofilms: an update","volume":"4","author":"Ramage","year":"2005","journal-title":"Eukaryot Cell"},{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0135","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1128\/AAC.01024-06","article-title":"Posaconazole enhances the activity of amphotericin B against Aspergillus hyphae in vitro","volume":"51","author":"Perkhofer","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0140","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1128\/AAC.50.4.1567-1569.2006","article-title":"Sequential or combination antifungal therapy with voriconazole and liposomal amphotericin B in a guinea pig model of invasive aspergillosis","volume":"50","author":"Kirkpatrick","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0145","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1111\/j.1469-0691.2004.00958.x","article-title":"Efficacy of voriconazole plus amphotericin B or micafungin in a guinea-pig model of invasive pulmonary aspergillosis","volume":"10","author":"Chandrasekar","year":"2004","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.ijantimicag.2015.03.006_bib0150","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/j.1439-0507.2011.02047.x","article-title":"Addition of DNase improves the in vitro activity of antifungal drugs against Candida albicans biofilms","volume":"55","author":"Martins","year":"2012","journal-title":"Mycoses"}],"container-title":["International Journal of Antimicrobial Agents"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0924857915001508?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0924857915001508?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T10:11:34Z","timestamp":1598955094000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0924857915001508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["S0924857915001508"],"URL":"https:\/\/doi.org\/10.1016\/j.ijantimicag.2015.03.006","relation":{},"ISSN":["0924-8579"],"issn-type":[{"value":"0924-8579","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prior in vitro exposure to voriconazole confers resistance to amphotericin B in Aspergillus fumigatus biofilms","name":"articletitle","label":"Article Title"},{"value":"International Journal of Antimicrobial Agents","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijantimicag.2015.03.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.","name":"copyright","label":"Copyright"}]}}