{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T19:28:12Z","timestamp":1790364492318,"version":"4.1.0"},"reference-count":18,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001734","name":"University of Copenhagen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001734","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012895","name":"Zoetis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012895","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Antimicrobial Agents"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.ijantimicag.2018.10.025","type":"journal-article","created":{"date-parts":[[2018,11,14]],"date-time":"2018-11-14T12:08:27Z","timestamp":1542197307000},"page":"868-872","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators"],"prefix":"10.1016","volume":"53","author":[{"given":"Kristin R.","family":"Baker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bimal","family":"Jana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1162-8592","authenticated-orcid":false,"given":"Anna Mette","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina Juul","family":"Vissing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanne M\u00f8rck","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2822-1927","authenticated-orcid":false,"given":"Henrik","family":"Franzyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Guardabassi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0001","series-title":"Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics","year":"2017"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0002","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmicb.2013.00103","article-title":"The intrinsic resistome of bacterial pathogens","volume":"4","author":"Olivares","year":"2013","journal-title":"Front Microbiol"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0003","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1021\/acsinfecdis.7b00071","article-title":"The challenge of overcoming antibiotic resistance: an adjuvant approach?","volume":"3","author":"Melander","year":"2017","journal-title":"ACS Infect Dis"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0004","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.mib.2016.05.005","article-title":"Treatment of Gram-negative bacterial infections by potentiation of antibiotics","volume":"33","author":"Zabawa","year":"2016","journal-title":"Curr Opin Microbiol"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0005","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1128\/mr.56.3.395-411.1992","article-title":"Agents that increase the permeability of the outer membrane","volume":"56","author":"Vaara","year":"1992","journal-title":"Microbiol Rev"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0006","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1111\/j.1469-0691.2010.03162.x","article-title":"Ciprofloxacin-resistant, CTX-M-15-producing Escherichia coli ST131 clone in extraintestinal infections in Italy","volume":"16","author":"Cerquetti","year":"2010","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0007","doi-asserted-by":"crossref","first-page":"42483","DOI":"10.1038\/srep42483","article-title":"The secondary resistome of multidrug-resistant Klebsiella pneumoniae","volume":"7","author":"Jana","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0008","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1021\/acs.bioconjchem.6b00013","article-title":"Antibacterial peptide nucleic acid\u2013antimicrobial peptide (PNA-AMP) conjugates: antisense targeting of fatty acid biosynthesis","volume":"27","author":"Hansen","year":"2016","journal-title":"Bioconjugate Chem"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0009","series-title":"Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals; approved standard\u2014fourth edition","year":"2013"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0010","series-title":"Performance standards for antimicrobial susceptibility testing","year":"2017"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0011","series-title":"Clinical microbiology procedures handbook","first-page":"140","article-title":"Synergism testing: broth microdilution checkerboard and broth macrodilution methods","year":"2010"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0012","doi-asserted-by":"crossref","first-page":"5995","DOI":"10.1128\/AAC.00537-16","article-title":"A high-throughput approach to identify compounds that impair envelope integrity in Escherichia coli","volume":"60","author":"Baker","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0013","doi-asserted-by":"crossref","first-page":"2864","DOI":"10.1021\/jm401335p","article-title":"Tailoring cytotoxicity of antimicrobial peptidomimetics with high activity against multidrug-resistant Escherichia coli","volume":"57","author":"Jahnsen","year":"2014","journal-title":"J Med Chem"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0014","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.ejpb.2015.01.013","article-title":"End group modification: efficient tool for improving activity of antimicrobial peptide analogues towards Gram-positive bacteria","volume":"95","author":"Jahnsen","year":"2015","journal-title":"Eur J Pharm Biopharm"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0015","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1021\/ja0666553","article-title":"Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of\u202f \u03b1\/\u03b2-peptides","volume":"129","author":"Schmitt","year":"2007","journal-title":"J Am Chem Soc"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0016","doi-asserted-by":"crossref","first-page":"2794","DOI":"10.1073\/pnas.0708254105","article-title":"Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides","volume":"105","author":"Chongsiriwatana","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0017","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/j.bbamem.2009.02.020","article-title":"Cell specificity, anti-inflammatory activity, and plausible bactericidal mechanism of designed Trp-rich model antimicrobial peptides","volume":"1788","author":"Hyon","year":"2009","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.ijantimicag.2018.10.025_bib0018","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1007\/s00726-010-0519-1","article-title":"Novel antimicrobial peptides from the venom of the eusocial bee Halictus sexcinctus (Hymenoptera: Halictidae) and their analogs","volume":"39","author":"Monincov\u00e1","year":"2009","journal-title":"Amino Acids"}],"container-title":["International Journal of Antimicrobial Agents"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0924857918303170?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0924857918303170?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T17:35:03Z","timestamp":1760376903000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0924857918303170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S0924857918303170"],"URL":"https:\/\/doi.org\/10.1016\/j.ijantimicag.2018.10.025","relation":{},"ISSN":["0924-8579"],"issn-type":[{"value":"0924-8579","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators","name":"articletitle","label":"Article Title"},{"value":"International Journal of Antimicrobial Agents","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijantimicag.2018.10.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}