{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T21:31:21Z","timestamp":1788384681753,"version":"build-2803163510"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,6,12]],"date-time":"2014-06-12T00:00:00Z","timestamp":1402531200000},"content-version":"vor","delay-in-days":284,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004612","name":"Funda\u00e7\u00e3o Arauc\u00e1ria","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004612","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biological Macromolecules"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.ijbiomac.2013.05.015","type":"journal-article","created":{"date-parts":[[2013,5,23]],"date-time":"2013-05-23T11:06:05Z","timestamp":1369307165000},"page":"93-99","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":51,"special_numbering":"C","title":["Sulfated polysaccharide of Caesalpinia ferrea inhibits herpes simplex virus and poliovirus"],"prefix":"10.1016","volume":"60","author":[{"given":"Nayara","family":"Lopes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00edgia Carla","family":"Faccin-Galhardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha Fernandes","family":"Espada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arcelina Cunha","family":"Pacheco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u00e1gila Maria Pontes Silva","family":"Ricardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa Elisa Carvalho","family":"Linhares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Nozawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0005","series-title":"Fields Virology, vol. 2","first-page":"2502","author":"Roizman","year":"2007"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0010","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1128\/CMR.16.1.79-95.2003","volume":"16","author":"Jones","year":"2003","journal-title":"Clinical Microbiology Reviews"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0015","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.det.2004.09.001","volume":"23","author":"Wu","year":"2005","journal-title":"Dermatologic Clinics"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0020","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1086\/521262","volume":"45","author":"Hjalmarrson","year":"2007","journal-title":"Clinical Infectious Diseases"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0025","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S0140-6736(84)92623-0","volume":"2","author":"Skoldenberg","year":"1984","journal-title":"Lancet"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0030","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.antiviral.2006.04.002","volume":"71","author":"Whitley","year":"2006","journal-title":"Antiviral Research"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0035","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.jinf.2006.11.013","volume":"54","author":"Mendoza","year":"2007","journal-title":"Journal of Infection"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0040","series-title":"Introdu\u00e7\u00e3o \u00e0 Virologia Humana","author":"Santos","year":"2008"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.ppat.1000791","volume":"6","author":"Lancaster","year":"2010","journal-title":"PLoS Pathogens"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0050","series-title":"Annual Report 2010","author":"Global Polio Eradication Initiative","year":"2011"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0055","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0166-3542(01)00206-6","volume":"53","author":"Rotbart","year":"2002","journal-title":"Antiviral Research"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0060","series-title":"Ethnomedicine: A Source of Complementary Therapeutics","first-page":"117","author":"Chattopadhyay","year":"2010"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0065","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/0378-8741(91)90112-Q","volume":"32","author":"Vlietinck","year":"1991","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0070","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0165-022X(01)00186-5","volume":"50","author":"Huheihel","year":"2002","journal-title":"Journal of Biochemical and Biophysical Methods"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0075","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/j.ijbiomac.2010.08.011","volume":"47","author":"Saha","year":"2010","journal-title":"International Journal of Biological Macromolecules"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0080","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jep.2009.04.034","volume":"124","author":"Sampaio","year":"2009","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0085","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/S0367-326X(01)00292-1","volume":"72","author":"Saeed","year":"2001","journal-title":"Fitoterapia"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0090","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.fitote.2006.02.011","volume":"77","author":"Sudhakar","year":"2006","journal-title":"Fitoterapia"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0095","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.carbpol.2008.07.036","volume":"75","author":"Cerqueira","year":"2009","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0100","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.ijbiomac.2009.06.007","volume":"45","author":"Singh","year":"2009","journal-title":"International Journal of Biological Macromolecules"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0105","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1139\/v55-127","volume":"33","author":"O\u2019Neill","year":"1995","journal-title":"Canadian Journal of Chemistry"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0110","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.micres.2006.03.011","volume":"163","author":"Melo","year":"2008","journal-title":"Microbiological Research"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0115","first-page":"106","volume":"14","author":"Yamamoto","year":"2009","journal-title":"Virus Review and Research"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0120","first-page":"39","volume":"50","author":"Nishimura","year":"1977","journal-title":"The Kitasato Archives of Experimental Medicine"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0125","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.jep.2012.04.018","volume":"142","author":"Faccin-Galhardi","year":"2012","journal-title":"Journal of Ethnophamacology"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0130","doi-asserted-by":"crossref","first-page":"219","DOI":"10.4149\/av_2011_03_255","volume":"55","author":"Minari","year":"2011","journal-title":"Acta Virologica"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0135","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1093\/jac\/dkh136","volume":"53","author":"Cheng","year":"2004","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1743-422X-9-37","volume":"9","author":"Rinc\u00e3o","year":"2012","journal-title":"Virology Journal"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0145","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/j.1472-765X.2007.02153.x","volume":"45","author":"Faccin","year":"2007","journal-title":"Letters in Applied Microbiology"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0150","doi-asserted-by":"crossref","first-page":"5268","DOI":"10.1128\/jvi.71.7.5268-5276.1997","volume":"71","author":"Tal-Singer","year":"1997","journal-title":"Journal of Virology"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0155","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.mcp.2009.11.003","volume":"24","author":"Pliaka","year":"2010","journal-title":"Molecular and Cellular Probes"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0160","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.antiviral.2010.02.318","volume":"86","author":"Ekblad","year":"2010","journal-title":"Antiviral Research"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0165","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.antiviral.2004.05.006","volume":"64","author":"Gong","year":"2004","journal-title":"Antiviral Research"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0170","doi-asserted-by":"crossref","first-page":"7994","DOI":"10.1158\/1078-0432.CCR-04-1087","volume":"10","author":"Zhao","year":"2004","journal-title":"Clinical Cancer Research"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0175","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1016\/j.carbpol.2010.10.017","volume":"83","author":"Peyman","year":"2011","journal-title":"Carbohydrate Polymers"},{"issue":"1","key":"10.1016\/j.ijbiomac.2013.05.015_bib0180","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.carbpol.2010.07.036","volume":"83","author":"Cerqueira","year":"2011","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0185","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0008-6215(96)00254-6","volume":"297","author":"Kalavelil","year":"1997","journal-title":"Carbohydrate Research"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0190","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.foodhyd.2011.10.005","volume":"27","author":"Souza","year":"2012","journal-title":"Food Hydrocolloids"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0195","series-title":"Infrared Absorption Spectroscopy","author":"Nakanishi","year":"1977"},{"issue":"3","key":"10.1016\/j.ijbiomac.2013.05.015_bib0200","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.carbpol.2008.07.036","volume":"75","author":"Cerqueira","year":"2009","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0205","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0008-6215(97)00241-3","article-title":"Cassia spestabilis DC seed galactomannan: structural, crystallographical and rheological studies","volume":"306","author":"Kapoor","year":"1998","journal-title":"Carbohydrate Research"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0210","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.carbpol.2010.05.031","article-title":"Caesalpinia ferrea var. ferrea seeds as a new source of partially substituted galactomannan","volume":"82","author":"Souza","year":"2010","journal-title":"Carbohydrate Polymers"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0215","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.ijbiomac.2009.09.003","volume":"45","author":"Chrestani","year":"2009","journal-title":"International Biological Macromolecules"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0220","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1055\/s-2006-958056","article-title":"Antiulcer action and toxicity of Styrax camporum and Caesalpinia ferrea","volume":"61","author":"Bacchi","year":"1995","journal-title":"Planta Medica"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0225","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1081\/IPH-100107337","volume":"23","author":"Queiroz","year":"2001","journal-title":"Immunopharmacology and Immunotoxicology"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0230","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0304-3835(01)00708-X","volume":"177","author":"Nakamura","year":"2002","journal-title":"Cancer Letters"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0235","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.jep.2011.12.012","volume":"139","author":"Pereira","year":"2012","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0240","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1093\/glycob\/cwn092","volume":"19","author":"Ghosh","year":"2009","journal-title":"Glycobiology"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0245","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0306-3623(96)00563-0","volume":"29","author":"Witvrouw","year":"1997","journal-title":"General Pharmacology"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0250","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.ijantimicag.2004.02.022","volume":"24","author":"Zhu","year":"2004","journal-title":"International Journal of Antimicrobial Agents"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0255","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.antiviral.2011.07.009","volume":"92","author":"Cardozo","year":"2011","journal-title":"Antiviral Research"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0260","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/BF00189609","volume":"179","author":"Biesert","year":"1990","journal-title":"Medical Microbiology and Immunology"},{"key":"10.1016\/j.ijbiomac.2013.05.015_bib0265","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1128\/AAC.31.9.1388","volume":"31","author":"Gonzalez","year":"1987","journal-title":"Antimicrobial Agents Chemotherapy"}],"container-title":["International Journal of Biological Macromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014181301300278X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014181301300278X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T06:51:43Z","timestamp":1758869503000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S014181301300278X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":53,"alternative-id":["S014181301300278X"],"URL":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2013.05.015","relation":{},"ISSN":["0141-8130"],"issn-type":[{"value":"0141-8130","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sulfated polysaccharide of Caesalpinia ferrea inhibits herpes simplex virus and poliovirus","name":"articletitle","label":"Article Title"},{"value":"International Journal of Biological Macromolecules","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2013.05.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V.","name":"copyright","label":"Copyright"}]}}