{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T17:05:49Z","timestamp":1774631149776,"version":"3.50.1"},"reference-count":104,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004602","name":"Program for New Century Excellent Talents in University","doi-asserted-by":"crossref","award":["NCET-13-0906"],"award-info":[{"award-number":["NCET-13-0906"]}],"id":[{"id":"10.13039\/501100004602","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81073065"],"award-info":[{"award-number":["81073065"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shanghai Municipal Commission of Health and Family Planning","award":["ZY3-CCCX-3-5001"],"award-info":[{"award-number":["ZY3-CCCX-3-5001"]}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["15DZ2292000"],"award-info":[{"award-number":["15DZ2292000"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biological Macromolecules"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.ijbiomac.2016.07.052","type":"journal-article","created":{"date-parts":[[2016,7,17]],"date-time":"2016-07-17T11:01:04Z","timestamp":1468753264000},"page":"431-440","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"special_numbering":"C","title":["The protective effect of herbal polysaccharides on ischemia-reperfusion injury"],"prefix":"10.1016","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6388-8743","authenticated-orcid":false,"given":"Qianqian","family":"Dong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0005","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.cytogfr.2014.10.013","article-title":"The angiopoietin\/TIE receptor system: focusing its role for ischemia-reperfusion injury","volume":"26","author":"Hilbert","year":"2015","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0010","doi-asserted-by":"crossref","first-page":"698","DOI":"10.2174\/1871527311312050015","article-title":"Oxidative stress and pathophysiology of ischemic stroke: novel therapeutic opportunities","volume":"12","author":"Rodrigo","year":"2013","journal-title":"CNS Neurol. Disord. Drug Targets"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0015","doi-asserted-by":"crossref","first-page":"638","DOI":"10.4330\/wjc.v6.i7.638","article-title":"Calpain system and its involvement in myocardial ischemia and reperfusion injury","volume":"6","author":"Neuhof","year":"2014","journal-title":"World J. Cardiol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0020","doi-asserted-by":"crossref","first-page":"113","DOI":"10.4103\/0971-9784.38791","article-title":"Inflammatory response to cardiac surgery and strategies to overcome it","volume":"7","author":"Kapoor","year":"2004","journal-title":"Ann. Card. Anaesth."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0025","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1602\/neurorx.1.1.17","article-title":"Neuronal death\/survival signaling pathways in celebral ischemia","volume":"1","author":"Suqawara","year":"2004","journal-title":"NeuroRX"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0030","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1097\/00001573-199511000-00005","article-title":"New strategies for intraoperative myocardical protection","volume":"10","author":"Flameng","year":"1995","journal-title":"Curr. Opin. Cardiol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0035","first-page":"12575","article-title":"protective effects of remote ischemic preconditioning in isolated rat hearts","volume":"8","author":"Teng","year":"2015","journal-title":"Int. J. Clin. Exp. Med."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0040","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1056\/NEJMoa1413534","article-title":"Remote ischemic preconditioning and outcomes of cardiac surgery","volume":"373","author":"Hausenloy","year":"2015","journal-title":"N. Eng. J. Med."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0045","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.carbpol.2015.02.029","article-title":"Synthesis characterization, antioxidant activity and neuroprotective effects of selenium polysaccharide from Radix hedysari","volume":"125","author":"Wei","year":"2015","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0050","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.carbpol.2014.09.071","article-title":"The anti-DHAV activities of Astragalus polysaccharide and its sulfate compared with those of BSRPS and its sulfate","volume":"117","author":"Chen","year":"2015","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0055","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.carbpol.2012.10.057","article-title":"Purification, characterization and anticoagulant activity of the polysaccharides from green tea","volume":"92","author":"Cai","year":"2013","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0060","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1016\/j.fitote.2012.09.029","article-title":"Structual characterization and radioprotection of bone marrow hematopoiesis of two novel polysaccharides from the root of Angelica sinensis (Oliv.) Diels","volume":"83","author":"Zhao","year":"2012","journal-title":"Fitoterapia"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0065","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.ijbiomac.2015.08.049","article-title":"Anti-diabetic properties of Momordica charantia L. polysaccharide in alloxaninduced diabetic mice","volume":"81","author":"Xu","year":"2015","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0070","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.ijbiomac.2014.04.004","article-title":"Hypolipidemic effect of the polysaccharides from Porphyra yezoensis","volume":"68","author":"Qian","year":"2014","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0075","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.carbpol.2015.06.046","article-title":"Antitumor and immunomodulatory activities of a water-soluble polysaccharide from Chaenomeles speciosa","volume":"132","author":"Xie","year":"2015","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0080","article-title":"Advances on bioactive polysaccharides from medicinal plants","volume":"13","author":"Xie","year":"2015","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0085","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s12012-002-0002-7","article-title":"Oxidative stress promotes blood cell-endothelial cell interactions in the microcirculation","volume":"2","author":"Cooper","year":"2002","journal-title":"Cardiovasc. Toxicol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0090","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1023\/A:1020718619155","article-title":"Nitric oxide and cardioprotection during ischemia- reperfusion","volume":"7","author":"Juqdutt","year":"2002","journal-title":"Heart Fail. Rev."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0095","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3389\/fphys.2015.00291","article-title":"Redox mechanisms of cardiomyocyte mitochondrial protection","volume":"6","author":"Bartz","year":"2015","journal-title":"Front. Physiol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0100","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0143-4160(03)00141-6","article-title":"Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity","volume":"34","author":"Arundine","year":"2003","journal-title":"Cell Calcium"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0105","doi-asserted-by":"crossref","first-page":"864946","DOI":"10.1155\/2015\/864946","article-title":"Molecular characterization of reactive oxygen species in myocardial ischemia-reperfusion injury","volume":"2015","author":"Zhou","year":"2015","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0110","doi-asserted-by":"crossref","first-page":"183469","DOI":"10.1155\/2015\/183469","article-title":"Mitochondrial dysfunction and autophagy in hepatic ischemia\/reperfusion injury","volume":"2015","author":"Go","year":"2015","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0115","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1126\/science.1195491","article-title":"Intravascular danger signals guide neutrophils to sites of sterile inflammation","volume":"330","author":"McDonald","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0120","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1161\/01.RES.71.6.1518","article-title":"Kinetics of C5a release in cardiac lymph of dogs experiencing coronary artery ischemia-reperfusion injury","volume":"71","author":"Dreyer","year":"1992","journal-title":"Circ. Res."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0125","doi-asserted-by":"crossref","first-page":"185","DOI":"10.2174\/157016109787455725","article-title":"Involvement of leukotriene pathway in the pathogenesis of ischemia-reperfusion injury and septic and non-septic shock","volume":"7","author":"Rossi","year":"2009","journal-title":"Curr. Vasc. Pharmacol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0130","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1111\/j.1939-1676.2001.tb01586.x","article-title":"Cell adhesion molecules, leukocyte trafficking, and strategies to reduce leukocyte infiltration","volume":"15","author":"Radi","year":"2001","journal-title":"J. Vet. Intern. Med."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0135","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1097\/00024382-199707000-00004","article-title":"Ischemia\/reperfusion-induced leukocyte\u2013endothelial interactions in postcapillary venules","volume":"8","author":"Eppihimer","year":"1997","journal-title":"Shock"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0140","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0008-6363(01)00434-5","article-title":"The inflammatory response in myocardial infarction","volume":"53","author":"Franqoqiannis","year":"2002","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0145","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.injury.2011.03.008","article-title":"The effect of ischemia reperfusion injury on skeletal muscle","volume":"43","author":"Gillani","year":"2012","journal-title":"Injury"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0150","doi-asserted-by":"crossref","first-page":"864946","DOI":"10.1155\/2015\/864946","article-title":"Molecular characterization of reactive oxygen species in myocardial ischemia-reperfusion injury","volume":"2015","author":"Zhou","year":"2015","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0155","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.ijbiomac.2015.05.024","article-title":"Optimization of extraction and antioxidant activity of polysaccharides from Salvia miltiorrhiza Bunge residue","volume":"79","author":"Jiang","year":"2015","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0160","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1016\/j.carbpol.2013.08.020","article-title":"Beneficial effects of a polysaccharide from Salvia miltiorrhiza on myocardial ischemia-reperfusion injury in rats","volume":"98","author":"Song","year":"2013","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0165","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.carbpol.2015.06.086","article-title":"Protective effect of a polysaccharide from Salvia miltiorrhiza on isoproterenol (ISO)-induced myocardial injury in rats","volume":"132","author":"Geng","year":"2015","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0170","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.carbpol.2014.12.038","article-title":"Cardiovascular effects in vitro of a polysaccharide from Salvia miltiorrhiza","volume":"121","author":"Geng","year":"2015","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0175","first-page":"1306","article-title":"Structural characterization of Astragalus polysaccharides using partial acid hydrolysis-hydrophilic interaction liquid chromatography\u2013mass spectrometry","volume":"32","author":"Liang","year":"2014","journal-title":"Se Pu"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0180","first-page":"7","article-title":"Effects of Astragalus saponin on hemodynamics and oxygen free radicals of rat cardiac muscle during ischemia reperfusion injury","volume":"7","author":"Zhang","year":"2000","journal-title":"Chin. J. Inf. Tradit. Chin. Med."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0185","first-page":"33","article-title":"Effect of astragalus membranaceus polysaccharide on myocardial ischemia-reperfusion injury in rats","volume":"14","author":"Zhang","year":"2007","journal-title":"Chin. J. Inf. Tradit. Chin. Med."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0190","doi-asserted-by":"crossref","first-page":"280493","DOI":"10.1155\/2013\/280493","article-title":"Astragalus polysaccharide suppresses the expression of adhesion molecules through the regulation of the p38 MAPK signaling pathway in human cardiac microvascular endothelial cells after ischemia-reperfusion injury","volume":"2013","author":"Hai-Yan","year":"2013","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0195","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.carbpol.2015.09.087","article-title":"Structural characterization and effect on anti-angiogenic activity of a fucoidan from Sargassum fusiforme","volume":"136","author":"Cong","year":"2016","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0200","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1016\/j.fct.2011.05.022","article-title":"Fucoidan a sulfated polysaccharide from brown algae, against myocardial ischemia-reperfusion injury in rats via regulating the inflammation response","volume":"49","author":"Li","year":"2011","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0205","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1097\/FJC.0b013e3182308c64","article-title":"Therapeutic potential of fucoidan in myocardial ischemia","volume":"58","author":"Manzo-Silberman","year":"2011","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0210","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.jacc.2004.09.068","article-title":"Antagonism of selectin function attenuates microvascular platelet deposition and platelet-mediated myocardial injury after transient ischemia","volume":"45","author":"Barrab\u00e9s","year":"2005","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0215","doi-asserted-by":"crossref","first-page":"4851","DOI":"10.3390\/md12094851","article-title":"Purification of a low molecular weight fucoidan for SPECT molecular imaging of myocardial infarction","volume":"12","author":"Saboural","year":"2014","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0220","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.2967\/jnumed.110.085852","article-title":"Radiolabeled fucoidan as a p-selectin targeting agent for in vivo imaging of platelet-rich thrombus and endothelial activation","volume":"52","author":"Rouzet","year":"2011","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0225","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.carbpol.2012.04.049","article-title":"Isolation, structure and bioactivities of the polysaccharides from Angelica sinensis (Oliv.) Diels: a review","volume":"89","author":"Jin","year":"2012","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0230","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1248\/bpb.30.1884","article-title":"Component and antioxidant properties of polysaccharide fractions isolated from Angelica sinensis (OLIV.) DIELS","volume":"30","author":"Yang","year":"2007","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0235","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.ijbiomac.2010.07.012","article-title":"Extraction, chemical analysis of Angelica sinensis polysaccharides and antioxidant activity of the polysaccharides in ischemia-reperfusion rats","volume":"47","author":"Zhang","year":"2010","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0240","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.ejpb.2010.07.003","article-title":"Poly(ethylene glycol)-radix Ophiopogonis polysaccharide conjugates: preparation, characterization, pharmacokinetics and in vitro bioactivity","volume":"76","author":"Lin","year":"2010","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0245","first-page":"832","article-title":"Active components of Polysaccharide of Ophiopogon Japonicus on acute myocardial ischemia","volume":"26","author":"Xu","year":"2004","journal-title":"Chin. Tradit. Pat. Med."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0250","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.ejps.2013.05.020","article-title":"Mono-PEGylated radix ophiopogonis polysaccharide for the treatment of myocardial ischemia","volume":"49","author":"Sun","year":"2013","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0255","first-page":"5555","article-title":"Injectable long-acting systems for Radix Ophiopogonis polysaccharide based on mono-PEGylation and in situ formation of a PLGA depot","volume":"9","author":"Shi","year":"2014","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0260","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.carbpol.2012.12.048","article-title":"Cardioprotective and antioxidant activities of a polysaccharide from the root bark of Aralia elata (Miq.) Seem","volume":"93","author":"Zhang","year":"2013","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0265","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.ijbiomac.2013.04.060","article-title":"Cardioprotective effect of Aralia elata polysaccharide on myocardial ischemic reperfusion (IR) injury in rats","volume":"59","author":"Zhang","year":"2013","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0270","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.ijbiomac.2013.04.047","article-title":"Protective role of Aralia elata polysaccharide on mercury(II)-induced cardiovascular oxidative injury in rats","volume":"59","author":"Zhang","year":"2013","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0275","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s12010-008-8187-2","article-title":"Production and characterization of the exopolysaccharides produced by Agaricus brasiliensis in submerged fermentation","volume":"151","author":"Lima","year":"2008","journal-title":"Appl. Biochem. Biotechnol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0280","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.ijbiomac.2010.01.008","article-title":"Characterization of chemical composition of Agaricus brasiliensis polysaccharides and its effect on myocardial SOD activity, MDA and caspase-3 level in ischemia-reperfusion rats","volume":"46","author":"Zhang","year":"2010","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0285","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.carbpol.2015.06.076","article-title":"A polysaccharide (PNPA) from Pleurotus nebrodensis offers cardiac protection against ischemia-reperfusion injury in rats","volume":"133","author":"Yan","year":"2015","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0290","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.gene.2014.11.027","article-title":"Evaluation of cardio-protective effect of soybean oligosaccharides","volume":"555","author":"Zhang","year":"2015","journal-title":"Gene"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0295","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.apjtb.2015.07.015","article-title":"Review on herbal medicine on brain ischemia and reperfusion","volume":"5","author":"Jivad","year":"2015","journal-title":"Asian Pac. J. Trop. Biomed."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0300","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/j.carres.2005.02.016","article-title":"Chemical characterization of the immunomodulating polysaccharide of Aloe vera L","volume":"340","author":"Tai-Nin Chow","year":"2005","journal-title":"Carbohydr. Res."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0305","first-page":"1217","article-title":"Acemannan, an extracted polysaccharide from Aloe vera: a literature review","volume":"9","author":"Sierra-Garc\u00eda","year":"2014","journal-title":"Nat. Prod. Commum."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0310","first-page":"655","article-title":"Effect of aloe polysaccharides pretreatment on the cerebral inflammatory response and lipid peroxidation in severe hemorrhagic shock rats first entering high altitude","volume":"50","author":"Lu","year":"2012","journal-title":"Zhonghau Wai Ke Za Zhi"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0315","doi-asserted-by":"crossref","first-page":"371","DOI":"10.3892\/mmr.2012.927","article-title":"Effect of aloe polysaccharide on caspase-3 expression following cerebral ischemia and reperfusion injury in rats","volume":"6","author":"Lu","year":"2012","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0320","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.carbpol.2013.04.057","article-title":"Characterization and hypoglycemic effect of a polysaccharide extracted from the fruit of Lycium barbarum L","volume":"98","author":"Zhu","year":"2013","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0325","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/s10735-012-9420-4","article-title":"Protective effects of Lycium barbarum polysaccharide on neonatal rat primary cultured hippocampal neurons injured by oxygen-glucose deprivation and reperfusion","volume":"43","author":"Chen","year":"2012","journal-title":"J. Mol. Histol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0330","first-page":"2760","article-title":"Neuroprotective effects of LBP on brain ischemic reperfusion neurodegeneration","volume":"17","author":"Wang","year":"2013","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0335","doi-asserted-by":"crossref","first-page":"e90780","DOI":"10.1371\/journal.pone.0090780","article-title":"Lycium barbarum polysaccharide prevents focal cerebral ischemic injury by inhibiting neuronal apoptosis in mice","volume":"9","author":"Wang","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0340","first-page":"726","article-title":"Structural characterization of a glucan isolated from Gastrodia elata","volume":"33","author":"Hong","year":"2010","journal-title":"Zhong Yao Cai"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0345","first-page":"40","article-title":"Effects of electroacupuncture intervention combined with polysaccharide of Gastrodia elata Blume on expression of nestin and cytokines of neural stem cells in the dentate gyrus of cerebral ischemia rats","volume":"39","author":"Miao","year":"2014","journal-title":"Zhen Ci Yan Jiu"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0350","first-page":"108","article-title":"Effect of electroacupuncture intervention combined with polysaccharide of Gastrodia elata Blume on expression of nestin and stem cell factor around the ischemic locus of frontal lobe cortex in local cerebral ischemia rats","volume":"40","author":"Zhao","year":"2015","journal-title":"Zhen Ci Yan Jiu"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0355","first-page":"474","article-title":"Effects of electroacupuncture combined with polysaccharide of gastrodia elate blume on expression of nestin and stem cell factor in thalamic ventroposterolateral nucleus in rats with focal cerebral ischemia","volume":"35","author":"Li","year":"2015","journal-title":"Zhongguo Zhen Jiu"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0360","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.carbpol.2014.04.013","article-title":"Characterization and biological effects of two polysaccharides isolated from Acanthopanax sciadophylloides","volume":"116","author":"Lee","year":"2015","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0365","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.etap.2013.01.004","article-title":"Acanthopanax senticosus exerts neuroprotective effects through HO-1 signaling in hippocampal and microglial cells","volume":"35","author":"Jin","year":"2013","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0370","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1016\/j.ijbiomac.2014.09.055","article-title":"Protective effects of Acanthopanax polysaccharides on cerebral ischemia-reperfusion injury and its mechanisms","volume":"72","author":"Xie","year":"2015","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0375","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/j.phytochem.2005.03.016","article-title":"Characterization of cell wall polysaccharides from the medicinal plant Panax notoginseng","volume":"66","author":"Zhu","year":"2005","journal-title":"Phytochemistry"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0380","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1142\/S0192415X09007582","article-title":"The effects and mechanism of saponins of Panax notoginseng on glucose metabolism in 3T3-L1 cells","volume":"37","author":"Kin","year":"2009","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0385","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.ijbiomac.2013.10.034","article-title":"Neuroprotective effect of Panax notoginseng plysaccharides against focal cerebral ischemia reperfusion injury in rats","volume":"63","author":"Jia","year":"2014","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0390","first-page":"996","article-title":"Notoginseng polysaccharide on rat ischemia-reperfusion injury of protection","volume":"32","author":"Li","year":"2015","journal-title":"J. Apoplexy Nerv. Dis."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0395","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.ijbiomac.2015.10.016","article-title":"Extraction, characterization and antioxidant activity of polysaccharides of spent mushroom compost of Ganoderma lucidum","volume":"82","author":"Zhang","year":"2016","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0400","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.jep.2010.06.023","article-title":"Neuroprotective effects of water-soluble Ganoderma lucidum polysaccharides on cerebral ischemic injury in rats","volume":"131","author":"Zhou","year":"2010","journal-title":"J. Ethnopharmcol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0405","first-page":"1950","article-title":"The purification and characterization of polysaccharides isolated from Ginkgo biloba and their in vitro antioxidant activities","volume":"34","author":"Hu","year":"2011","journal-title":"Zhong Yao Cai"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0410","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.ijbiomac.2010.02.002","article-title":"Structure characterization and antioxidant activity of a novel polysaccharide isolated from Ginkgo biloba","volume":"46","author":"Yuan","year":"2010","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0415","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1016\/j.carbpol.2013.07.045","article-title":"Therapeutic effect of Ginkgo biloba polysaccharide in rats with focal cerebral ischemia\/reperfusion (IR) injury","volume":"98","author":"Yang","year":"2013","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0420","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.carres.2014.10.015","article-title":"Pectic polysaccharide from the green fruits of Momordica charantia (Karela): structural characterization and study of immunoenhancing and antioxidant properties","volume":"401","author":"Panda","year":"2015","journal-title":"Carbohydr. Res."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0425","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1002\/bip.22312","article-title":"Catalytic synthesis and antioxidant activity of sulfated polysaccharide from Momordica charantia L","volume":"101","author":"Liu","year":"2014","journal-title":"Biopolymers"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0430","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.neuropharm.2014.11.020","article-title":"Momordica charantia polysaccharides could protect against cerebral ischemia\/reperfusion injury through inhibiting oxidative stress mediated c-Jun N-terminal kinase 3 signaling pathway","volume":"91","author":"Gong","year":"2015","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0435","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.carbpol.2012.03.078","article-title":"Characterization of antioxidant polysaccharides from Auricularia auricular using microwave-assisted extraction","volume":"89","author":"Zeng","year":"2012","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0440","first-page":"423","article-title":"Study of the effects of Auricularia auricular polysaccharide on local ischemia\/reperfusion injury in rat","volume":"26","author":"Ye","year":"2010","journal-title":"Zhongguo Ying Yong Sheng Li Xue Za Zhi"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0445","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/nrgastro.2012.225","article-title":"Ischemia-reperfusion injury in liver transplantation\u2014from bench to bedside","volume":"10","author":"Zhai","year":"2013","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0450","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1111\/nep.12614","article-title":"Remote ischemia pre-conditioning for the prevention of acute kidney injury","volume":"21","author":"Ho","year":"2016","journal-title":"Nephrology (Carlton)"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0455","doi-asserted-by":"crossref","first-page":"926381","DOI":"10.1155\/2014\/926381","article-title":"The metabolism of polysaccharide from atractylodes macrocephala koidz and its effect on intestinal microflora","volume":"2014","author":"Wang","year":"2014","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0460","first-page":"1193","article-title":"Effect of atractylodes macrocephalaon polysaccharides for reducing liver ischemia\/reperfusion injury in rats after orthotopic liver autotransplantation","volume":"30","author":"Zhang","year":"2010","journal-title":"CJITWM"},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0465","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1142\/S0192415X11008981","article-title":"Protective effects of Atractylodes macrocephala polysaccharide on liver ischemia-reperfusion injury and its possible mechanism in rats","volume":"39","author":"Jin","year":"2011","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0470","first-page":"62","article-title":"The protective effect of atractylodes macrocephalaon polysaccharide on hepatic ischemia reperfusion injury in rats","volume":"20","author":"Zhang","year":"2011","journal-title":"Chin. J. Gen. Surg."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0475","first-page":"4","article-title":"Effect of atractylodes macrocephalaon polysaccharide pre-disposal treatment after ischemia reperfusion injury of liver on the chondriosome structure of hepatic cell in rats","volume":"23","author":"Zhang","year":"2011","journal-title":"J. Hepatopancreatobiliary Surg."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0480","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.ijbiomac.2012.06.031","article-title":"Purification, characterization and anticancer activity of a polysaccharide from Panax ginseng","volume":"51","author":"Li","year":"2012","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0485","first-page":"370","article-title":"Effects of ginseng polysaccharide on the function of platelet aggregation in hepatic ischemia reperfusion of rabbits","volume":"21","author":"Shi","year":"2009","journal-title":"J. Hepatopancreatobiliary Surg."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0490","first-page":"24","article-title":"Effects of Ginseng Polysauharides on NO, ET and ALT in hepatic ischemia reperfusion of rabbits","volume":"21","author":"Liang","year":"2009","journal-title":"J. Hepatopancreatobiliary Surg."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0495","first-page":"109","article-title":"Ginseng polysauharides interfering changes of lipid peroxidation during hepatic ischemia-Reperfusion in rabbits","volume":"17","author":"Zheng","year":"2009","journal-title":"Chin. J. Arterioscler."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0500","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.ijbiomac.2015.08.022","article-title":"Antioxidant activity and optimization of extraction of polysaccharide from the roots of Dipsacus asperoides","volume":"81","author":"Tan","year":"2015","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0505","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.ijbiomac.2012.12.024","article-title":"Attenuation of renal ischemia\/reperfusion injury by a polysaccharide from the roots of Dipsacus asperoides","volume":"56","author":"Cong","year":"2013","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0510","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1016\/j.carbpol.2012.07.062","article-title":"Protective effect of a polysaccharide from stem of Codonopsis pilosula against renal ischemia\/reperfusion injury in rats","volume":"90","author":"Li","year":"2012","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0515","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.ijbiomac.2012.09.009","article-title":"Evaluation of in vivo antioxidant activity of Hericium erinaceus polysaccharides","volume":"52","author":"Han","year":"2013","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2016.07.052_bib0520","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.ijbiomac.2010.12.005","article-title":"Chemical characterization and Ameliorating effect of polysaccharide from Chinese jujube on intestine oxidative injury by ischemia and reperfusion","volume":"48","author":"Wang","year":"2011","journal-title":"Int. J. Biol. Macromol."}],"container-title":["International Journal of Biological Macromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813016308753?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813016308753?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T08:07:44Z","timestamp":1718698064000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0141813016308753"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":104,"alternative-id":["S0141813016308753"],"URL":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2016.07.052","relation":{},"ISSN":["0141-8130"],"issn-type":[{"value":"0141-8130","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The protective effect of herbal polysaccharides on ischemia-reperfusion injury","name":"articletitle","label":"Article Title"},{"value":"International Journal of Biological Macromolecules","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2016.07.052","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}