{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T02:20:18Z","timestamp":1773109218838,"version":"3.50.1"},"reference-count":80,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biological Macromolecules"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.ijbiomac.2018.05.009","type":"journal-article","created":{"date-parts":[[2018,5,4]],"date-time":"2018-05-04T21:28:31Z","timestamp":1525469311000},"page":"194-207","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Probing the potency of triazole tethered Schiff base complexes and the effect of substituents on their biological attributes"],"prefix":"10.1016","volume":"116","author":[{"given":"Ponnukalai Ponya","family":"Utthra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natarajan","family":"Raman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0005","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/nrc2167","article-title":"The resurgence of platinum-based cancer chemotherapy","volume":"7","author":"Kelland","year":"2007","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0010","series-title":"Cisplatin Chemistry and Biochemistry of a Leading Anticancer Compound","year":"1999"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0015","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.cbpa.2007.11.013","article-title":"New trends for metal complexes with anticancer activity","volume":"12","author":"Bruijnincx","year":"2008","journal-title":"Curr. Opin. Chem. Biol."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2017.08.023","article-title":"Acridone-pyrimidine hybrids- design, synthesis, cytotoxicity studies in resistant and sensitive cancer cells and molecular docking studies","author":"Murahari","year":"2017","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0025","doi-asserted-by":"crossref","first-page":"10210","DOI":"10.1039\/C4DT03879G","article-title":"Mixed ligand copper(II) dicarboxylate complexes: the role of co-ligand hydrophobicity in DNA binding, double-strand DNA cleavage, protein binding and cytotoxicity","volume":"44","author":"Loganathan","year":"2015","journal-title":"Dalton Trans."},{"key":"10.1016\/j.ijbiomac.2018.05.009_rf0030","doi-asserted-by":"crossref","first-page":"75","DOI":"10.2174\/187152007779314053","article-title":"Photoactivatable platinum complexes","volume":"7","author":"Bednarski","year":"2007","journal-title":"Anti Cancer Agents Med. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_rf0035","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1002\/med.20000","article-title":"DNA minor groove binders as potential antitumor and antimicrobial agents","volume":"24","author":"Baraldi","year":"2004","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.ijbiomac.2018.05.009_rf0040","doi-asserted-by":"crossref","first-page":"2805","DOI":"10.2174\/092986705774454698","article-title":"Advances in DNA-ligands with groove binding, intercalating and\/or alkylating activity: chemistry, DNA-binding and biology","volume":"12","author":"Pindur","year":"2005","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_rf0045","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1039\/B609495C","article-title":"Synthetic metallomolecules as agents for the control of DNA structure","volume":"36","author":"Richards","year":"2007","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0035","article-title":"A new azo-Schiff base: synthesis, characterization, biological activity and theoretical studies of its complexes","volume":"3895","author":"Al Zoubi","year":"2017","journal-title":"Appl. Organomet. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0040","article-title":"Structure activity relationship (SAR) study and design strategies of nitrogen-containing heterocyclic moieties for their anticancer activities","author":"Akhtar","year":"2016","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2017.04.152","article-title":"DNA interaction, antioxidant and in vitro cytotoxic activities of some mononuclear metal(II) complexes of a bishydrazone ligand","author":"Justin Dhanaraj","year":"2017","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0050","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1016\/j.ejmech.2011.03.039","article-title":"New quinolin-4-yl-1, 2, 3-triazoles carrying amides, sulphonamides and amidopiperazines as potential antitubercular agents","volume":"46","author":"Thomas","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0055","doi-asserted-by":"crossref","first-page":"4435","DOI":"10.1016\/j.ejmech.2010.07.002","article-title":"Synthesis and antifungal evaluation of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase","volume":"45","author":"Yu","year":"2010","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0060","doi-asserted-by":"crossref","first-page":"383","DOI":"10.2147\/DDDT.S58680","article-title":"Triazole derivatives with improved in vitro antifungal activity over azole drugs","volume":"8","author":"Yu","year":"2014","journal-title":"Drug Des. Dev. Ther."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0065","first-page":"1459","article-title":"Design, synthesis, and antifungal activities of novel triazole derivatives containing the benzyl group","volume":"9","author":"Xu","year":"2015","journal-title":"Drug Des. Dev. Ther."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0070","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1007\/s12272-012-1105-8","article-title":"Design, synthesis, and biological evaluation of novel 1, 2, 4-triazole derivatives as antifungal agent","volume":"35","author":"Chai","year":"2012","journal-title":"Arch. Pharm. Res."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0075","doi-asserted-by":"crossref","first-page":"11333","DOI":"10.3390\/molecules190811333","article-title":"Synthesis and antifungal activity of novel triazole compounds containing piperazine moiety","volume":"19","author":"Wang","year":"2014","journal-title":"Mol. (Basel Switzerland)"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0080","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1007\/s12272-013-0063-0","article-title":"Synthesis and antifungal activity of the novel triazole derivatives containing 1,2,3-triazole fragment","volume":"36","author":"Yu","year":"2013","journal-title":"Arch. Pharm. Res."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0085","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1016\/j.bmcl.2017.03.062","article-title":"Design, synthesis, and in vitro evaluation of novel antifungal triazoles","volume":"27","author":"Xie","year":"2017","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0090","doi-asserted-by":"crossref","first-page":"3320","DOI":"10.1016\/j.ejmech.2010.04.015","article-title":"Synthesis of 2-substituted-N-[4-(1-methyl-4,5-diphenyl-1H-imidazole-2-yl)phenyl]acetamide derivatives and evaluation of their anticancer activity","volume":"45","author":"Ozkay","year":"2010","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0095","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1081\/SIM-120021648","article-title":"Synthesis and characterization of N-(o-vanillinidene)-p-anisidine and N,N\u2032-bis (o-vanillinidene) ethylenediamine and their metal complexes","volume":"33","author":"Maurya","year":"2003","journal-title":"Synth. React. Inorg. Met. Org. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0100","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.jphotobiol.2016.02.033","article-title":"Scrutinizing the DNA damaging and antimicrobial abilities of triazole appended metal complexes","volume":"158","author":"Utthra","year":"2016","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0105","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0010-8545(00)80009-0","article-title":"The use of conductivity measurements in organic solvents for the characterisation of coordination compounds","volume":"7","author":"Geary","year":"1971","journal-title":"Coord. Chem. Rev."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0110","series-title":"Text Book of Quantitative Chemical Analysis","author":"Vogel","year":"1989"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0115","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1016\/j.jorganchem.2005.09.052","article-title":"Synthesis, characterisation and X-ray structures of diorganotin(IV) and iron(III) complexes of dianionic terdentate Schiff base ligands","volume":"691","author":"Labisbal","year":"2006","journal-title":"J. Organomet. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_rf0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.saa.2013.07.074","article-title":"Mn(II) and Cu(II) complexes of a bidentate Schiff's base ligand: spectral, thermal, molecular modelling and mycological studies","volume":"117","author":"Tyagi","year":"2014","journal-title":"Spectrochim. Acta A"},{"key":"10.1016\/j.ijbiomac.2018.05.009_rf0140","article-title":"Synthesis, characterization of 1,2,4-triazole Schiff base derived 3d-metal complexes: induces cytotoxicity in HepG2, MCF-7 cell line, BSA binding, fluorescence and DFT study","author":"Tyagi","year":"2016","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0125","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/BF02708270","article-title":"Copper(II), cobalt(II), nickel(II) and zinc(II) complexes of Schiff base derived from benzil-2,4-dinitrophenylhydrazone with aniline","volume":"116","author":"Raman","year":"2004","journal-title":"J. Chem. Sci."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0130","series-title":"Inorganic Electronic Spectroscopy","author":"Lever","year":"1984"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0135","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1081\/SIM-200026581","article-title":"Template synthesis and characterization of 12 and 14-membered pendant armed tetraazamacrocyclic transition metal complexes: a photoelectron spectroscopic study","volume":"34","author":"Srivastava","year":"2004","journal-title":"Synth. React. Inorg. Metal Org. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0140","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.molstruc.2016.06.034","article-title":"Effective DNA binding and cleaving tendencies of malonic acid coupled transition metal complexes","volume":"1123","author":"Pravin","year":"2016","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0145","series-title":"Coordination Chemistry","author":"Banerjea","year":"1993"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0150","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/BFb0111454","article-title":"A new look at the stereochemistry and electronic properties of complexes of the copper (II) ion","volume":"57","author":"Hathaway","year":"1984","journal-title":"Struct. Bond."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0155","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0010-8545(00)80135-6","article-title":"The electronic properties and stereochemistry of mono-nuclear complexes of the copper (II) ion","volume":"5","author":"Hathaway","year":"1970","journal-title":"Coord. Chem. Rev."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0160","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.ejmech.2005.06.006","article-title":"Synthesis, characterization and biological studies of Co (II), Ni (II), Cu (II) and Zn (II) complexes with bidentate Schiff bases derived by heterocyclic ketone","volume":"41","author":"Singh","year":"2006","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0165","article-title":"Synthesis, structure and in vitro antiproliferative activities of oxamido-bridged dicopper(II) complexes: a comparative study of experimental evidence and molecular docking of DNA\/protein binding","author":"Wang","year":"2017","journal-title":"Appl. Organomet. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0170","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/s007750000177","article-title":"Preparation, characterization and crystal structures of manganese(II), iron(III) and copper(II) complexes of the bis [di-1, 1-(2-pyridyl) ethyl] amine (BDPEA) ligand; evaluation of their DNA cleavage activities","volume":"6","author":"Hemmert","year":"2001","journal-title":"J. Biol. Inorg. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0175","doi-asserted-by":"crossref","first-page":"2572","DOI":"10.1021\/ja00060a004","article-title":"Antiparallel side-by-side heterodimer for sequence-specific recognition in the minor groove of DNA by a distamycin\/1-methylimidazole-2-carboxamide-netropsin pair","volume":"115","author":"Mrksich","year":"1993","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0180","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1016\/j.jinorgbio.2005.08.002","article-title":"Synthesis and DNA binding of \u03bc-[2, 9-bis (2-imidazo [4, 5-f][1, 10] phenanthroline)-1, 10-phenanthroline] bis [1, 10-phenanthrolinecopper (II)]","volume":"99","author":"Wu","year":"2005","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinorgbio.2017.07.008","article-title":"Aryl-1H-imidazole[4,5f][1,10]phenanthroline Cu(II) complexes: electrochemical and DNA interaction studies","author":"Rajebhosale","year":"2017","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0190","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1089\/dna.2007.0669","article-title":"DNA interaction with novel antitumor estradiol\u2013platinum (II) hybrid molecule: a comparative study with cisplatin drug","volume":"27","author":"N'soupkpo\u00e9-Kossi","year":"2008","journal-title":"DNA Cell Biol."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0195","series-title":"Bioinorganic Chemistry","author":"Bertini","year":"1994"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0200","article-title":"Ruthenium(II)\u2013arene complexes of diimines: effect of diimine intercalation and hydrophobicity on DNA and protein binding and cytotoxicity","author":"Ganeshpandian","year":"2017","journal-title":"Appl. Organomet. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinorgbio.2017.07.015","article-title":"New copper(II) thiohydantoin complexes: synthesis, characterization, and assessment of their interaction with bovine serum albumin and DNA","author":"Tishchenko","year":"2017","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_rf0230","article-title":"Heteroleptic Schiff base complexes containing terpyridine as chemical nucleases and their biological potential: a study of DNA binding and cleaving, antimicrobial and cytotoxic tendencies","author":"Utthra","year":"2016","journal-title":"Appl. Organomet. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_rf0235","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.molstruc.2017.09.002","article-title":"Screening the efficient biological prospects of triazole allied mixed ligand metal complexes","volume":"1150","author":"Utthra","year":"2017","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtusci.2014.01.005","article-title":"Synthesis, structure and antibacterial activity of some triorganotin(IV) complexes with a benzamidoalanine ligand","author":"Yousif","year":"2014","journal-title":"J. Taibah Univ. Sci."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0220","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1080\/17415990600904697","article-title":"Synthesis and antimicrobial evaluation of some pyrazolo-thiazolyl alkoxy-1H-isoindole-1, 3(2H)-dione derivatives","volume":"27","author":"Jat","year":"2006","journal-title":"J. Sulfur. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0225","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.jinorgbio.2003.09.003","article-title":"DNA binding and cleavage properties of certain tetrammine ruthenium (II) complexes of modified 1, 10-phenanthrolines\u2013effect of hydrogen-bonding on DNA-binding affinity","volume":"98","author":"Maheswari","year":"2004","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0230","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/406161","article-title":"DNA binding and cleavage activities of Na [B (Glu)(OH)2]\u00b72H2O, Na [B (Cit)(OH)2]\u00b72H2O, Li [B (Sal)(OH)2], and Mg[B(Sal)(OH)2]\u00b72H2O complexes","volume":"2013","author":"Arslantas","year":"2013","journal-title":"J. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0235","doi-asserted-by":"crossref","first-page":"3072","DOI":"10.1021\/ic061753a","article-title":"DNA binding studies of novel copper (II) complexes containing l-tryptophan as chiral auxiliary: in vitro antitumor activity of Cu\u2212Sn2 complex in human neuroblastoma cells","volume":"46","author":"Chauhan","year":"2007","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0240","doi-asserted-by":"crossref","first-page":"4237","DOI":"10.1021\/bi00067a011","article-title":"GC Base sequence recognition by oligo(imidazolecarboxamide) and C-terminus-modified analogues of distamycin deduced from circular dichroism, proton nuclear magnetic resonance, and methidiumpropylethylenediaminetetraacetate-iron(II) footprinting studies","volume":"32","author":"Lee","year":"1993","journal-title":"Biochemistry"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0245","doi-asserted-by":"crossref","first-page":"2528","DOI":"10.1021\/ja00294a054","article-title":"Design, synthesis, and DNA binding properties of bifunctional intercalators. Comparison of polymethylene and diphenyl ether chains connecting phenanthridine","volume":"107","author":"Cory","year":"1985","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0250","series-title":"Electrochemical Methods: Fundamentals and Applications","author":"Bard","year":"1980"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0255","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.jinorgbio.2004.11.018","article-title":"Mixed ligand copper(II) complexes of phenanthroline\/bipyridyl and curcumin diketimines as DNA intercalators and their electrochemical behavior under Nafion\u00ae and clay modified electrodes","volume":"99","author":"Annaraj","year":"2005","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0260","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0162-0134(00)00132-X","article-title":"DNA-binding and photocleavage studies of cobalt(III) polypyridyl complexes","volume":"83","author":"Zhang","year":"2001","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0265","article-title":"Interaction of amino acid Schiff base metal complexes with DNA\/BSA protein and antibacterial activity: Spectral studies, DFT calculations and molecular docking simulations","author":"Neelakantan","year":"2017","journal-title":"Appl. Organomet. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0270","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1002\/bip.360210904","article-title":"Structure of methylene blue\u2013DNA complexes studied by linear and circular dichroism spectroscopy","volume":"21","author":"Norden","year":"1982","journal-title":"Biopolymers"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0275","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0162-0134(96)00194-8","article-title":"Study of the interaction between novel ruthenium (II)-polypyridyl complexes and calf thymus DNA","volume":"66","author":"Yang","year":"1997","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0280","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0022-2836(61)80004-1","article-title":"Structural considerations in the interaction of DNA and acridines","volume":"3","author":"Lerman","year":"1961","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0285","doi-asserted-by":"crossref","first-page":"4423","DOI":"10.1021\/ja00064a001","article-title":"Binding and kinetics studies of oxidation of DNA by oxoruthenium (IV)","volume":"115","author":"Neyhart","year":"1993","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0290","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0005-2787(73)90004-X","article-title":"DNA stiffening and elongation caused by the binding of ethidium bromide","volume":"319","author":"Reinert","year":"1973","journal-title":"Biochim. Biophys. Acta"},{"issue":"33","key":"10.1016\/j.ijbiomac.2018.05.009_bb0295","doi-asserted-by":"crossref","first-page":"5036","DOI":"10.1002\/ejic.200900763","article-title":"Synthesis, X-ray crystal structures, DNA binding and nuclease activities of two novel 1, 2, 4-triazole-based Cu(II) complexes","author":"Li","year":"2009","journal-title":"Eur. J. Inorg. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0300","first-page":"1794","article-title":"In-silico identification and molecular docking studies of quinolone resistance determining region (QRDR) of E. coli DNA Gyrase-A with ofloxacin Schiff Bases","volume":"5","author":"Kumar","year":"2013","journal-title":"Int. J. Pharm. Tech. Res."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0305","article-title":"DNA interaction, antioxidant and in vitro cytotoxic activities of some mononuclear metal(II) complexes of a bishydrazone ligand","author":"Dhanaraj","year":"2017","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0310","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.poly.2006.08.026","article-title":"Synthesis, characterization, DNA interaction and cleavage activity of new mixed ligand copper(II) complexes with heterocyclic bases","volume":"26","author":"Babu","year":"2007","journal-title":"Polyhedron"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0315","doi-asserted-by":"crossref","first-page":"6587","DOI":"10.1039\/C6RA24770A","article-title":"Synthesis of chiral R\/S-pseudopeptide-based Cu(II) & Zn(II) complexes for use in targeted delivery for antitumor therapy: Enantiomeric discrimination with CT-DNA and pBR322 DNA hydrolytic cleavage mechanism","volume":"7","author":"Parveen","year":"2017","journal-title":"RSC Adv."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0320","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.ijbiomac.2015.06.001","article-title":"Targeting protein kinase and DNA molecules by diimine\u2013phthalate complexes in antiproliferative activity","volume":"79","author":"Pravin","year":"2015","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0325","first-page":"910","article-title":"Plant extracts with metal ions as potential antimicrobial agents","volume":"55","author":"Tweedy","year":"1964","journal-title":"Phytopathalogy"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0330","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.saa.2012.12.011","article-title":"Synthesis, antimicrobial, DNA-binding and photonuclease studies of cobalt(III) and nickel(II) Schiff base complexes","volume":"105","author":"Sangeetha Gowda","year":"2013","journal-title":"Spectrochim. Acta A"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0335","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.saa.2013.06.096","article-title":"Potential bioactive Schiff base compounds: synthesis, characterization, X-ray structures, biological screenings and interaction with Salmon sperm DNA","volume":"116","author":"Sirajuddin","year":"2013","journal-title":"Spectrochim. Acta A"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0340","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.saa.2013.04.055","article-title":"Synthesis, spectral characterization and biological activity of metal(II) complexes with 4-aminoantipyrine derivatives","volume":"113","author":"Leelavathy","year":"2013","journal-title":"Spectrochim. Acta A"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0345","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.saa.2006.06.031","article-title":"Synthesis, characterization and biological activity of some platinum(II) complexes with Schiff bases derived from salicylaldehyde, 2-furaldehyde and phenylenediamine","volume":"67","author":"Akmal","year":"2007","journal-title":"Spectrochim. Acta A"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0350","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.saa.2012.08.034","article-title":"Synthesis, characterization, biological activity and equilibrium studies of metal (II) ion complexes with tridentate hydrazone ligand derived from hydralazine","volume":"98","author":"El-Sherif","year":"2012","journal-title":"Spectrochim. Acta A"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0355","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1016\/0022-1902(74)80739-6","article-title":"Some aspects of the reactivity of amino acids coordinated to metal ions","volume":"36","author":"Pasini","year":"1974","journal-title":"J. Inorg. Nucl. Chem."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0360","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1128\/AAC.01781-12","article-title":"Copper-boosting compounds: a novel concept for antimycobacterial drug discovery","volume":"57","author":"Speer","year":"2013","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0365","doi-asserted-by":"crossref","first-page":"3727","DOI":"10.1128\/AAC.02316-13","article-title":"Copper complexation screen reveals compounds with potent antibiotic properties against methicillin-resistant Staphylococcus aureus","volume":"58","author":"Haeili","year":"2014","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0370","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1039\/C3MT00348E","article-title":"Antimicrobial effects of copper(II) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action","volume":"6","author":"Djoko","year":"2014","journal-title":"Metallomics"},{"key":"10.1016\/j.ijbiomac.2018.05.009_bb0375","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/j.chembiol.2014.06.009","article-title":"Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection","volume":"21","author":"Festa","year":"2014","journal-title":"Chem. Biol."}],"container-title":["International Journal of Biological Macromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813018311322?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813018311322?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T07:03:06Z","timestamp":1758870186000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0141813018311322"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":80,"alternative-id":["S0141813018311322"],"URL":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2018.05.009","relation":{},"ISSN":["0141-8130"],"issn-type":[{"value":"0141-8130","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Probing the potency of triazole tethered Schiff base complexes and the effect of substituents on their biological attributes","name":"articletitle","label":"Article Title"},{"value":"International Journal of Biological Macromolecules","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2018.05.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}