{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T13:14:03Z","timestamp":1788441243859,"version":"build-2803163510"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003489","name":"Henan University of Technology","doi-asserted-by":"publisher","award":["2017QNJH10"],"award-info":[{"award-number":["2017QNJH10"]}],"id":[{"id":"10.13039\/501100003489","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003489","name":"Henan University of Technology","doi-asserted-by":"publisher","award":["2017BS011"],"award-info":[{"award-number":["2017BS011"]}],"id":[{"id":"10.13039\/501100003489","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009101","name":"Henan provincial education department","doi-asserted-by":"publisher","award":["19A180015"],"award-info":[{"award-number":["19A180015"]}],"id":[{"id":"10.13039\/501100009101","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007957","name":"Chongqing Municipal Education Commission","doi-asserted-by":"publisher","award":["KJQN201800540"],"award-info":[{"award-number":["KJQN201800540"]}],"id":[{"id":"10.13039\/501100007957","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003787","name":"Natural Science Foundation of Hebei Province","doi-asserted-by":"publisher","award":["C2018402265"],"award-info":[{"award-number":["C2018402265"]}],"id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biological Macromolecules"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.ijbiomac.2019.06.186","type":"journal-article","created":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T12:38:03Z","timestamp":1561466283000},"page":"1106-1111","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Efficient biosynthesis of anticancer polysaccharide by a mutant Chaetomium globosum ALE20 via non-sterilized fermentation"],"prefix":"10.1016","volume":"136","author":[{"given":"Zichao","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuyang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhangtao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenwen","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Libo","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiru","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0005","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.biortech.2017.11.019","article-title":"Mixed bacterial culture mediated direct conversion of bio-glycerol to diols","volume":"250","author":"Parate","year":"2018","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0010","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.biortech.2017.10.102","article-title":"Effect of lipid-free microalgal biomass and waste glycerol on growth and lipid production of Scenedesmus obliquus: innovative waste recycling for extraordinary lipid production","volume":"249","author":"Abomohra","year":"2018","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0015","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.biortech.2018.02.024","article-title":"Investigations in sonication-induced intensification of crude glycerol fermentation to dihydroxyacetone by free and immobilized Gluconobacter oxydans","volume":"256","author":"Dikshit","year":"2018","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0020","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ymben.2016.11.008","article-title":"Increased production of L-serine in Escherichia coli through adaptive laboratory evolution","volume":"39","author":"Mundhada","year":"2017","journal-title":"Metab. Eng."},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0025","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.biortech.2015.03.011","article-title":"Improving high carbon dioxide tolerance and carbon dioxide fixation capability of Chlorella sp. by adaptive laboratory evolution","volume":"185","author":"Li","year":"2015","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0030","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.biortech.2016.01.022","article-title":"Strain improvement of Chlorella sp. for phenol biodegradation by adaptive laboratory evolution","volume":"205","author":"Wang","year":"2016","journal-title":"Bioresour. Technol."},{"issue":"1","key":"10.1016\/j.ijbiomac.2019.06.186_bb0035","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.procbio.2015.11.005","article-title":"Enhanced oxalic acid production from corncob by a methanol-resistant strain of Aspergillus niger using semi solid-sate fermentation","volume":"51","author":"Mai","year":"2016","journal-title":"Process Biochem."},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0040","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.biortech.2017.12.055","article-title":"Malic acid production by chemically induced Aspergillus niger MTCC 281 mutant from crude glycerol","volume":"251","author":"Iyyappan","year":"2018","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0045","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.biortech.2018.07.079","article-title":"Adaptive evolution of microalgae Schizochytrium sp. under high salinity stress to alleviate oxidative damage and improve lipid biosynthesis","volume":"267","author":"Sun","year":"2018","journal-title":"Bioresour. Technol."},{"issue":"4","key":"10.1016\/j.ijbiomac.2019.06.186_bb0050","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3390\/biom8040171","article-title":"Anticancer activity of polysaccharides produced from glycerol and crude glycerol by an endophytic fungus Chaetomium globosum CGMCC 6882 on human lung cancer A549 cells","volume":"8","author":"Wang","year":"2018","journal-title":"Biomolecules"},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0055","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.wasman.2016.10.034","article-title":"Enhanced recovery of valuable metals from spent lithium-ion batteries through optimization of organic acids produced by Aspergillus niger","volume":"60","author":"Bahaloo-Horeh","year":"2017","journal-title":"Waste Manag."},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0060","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.biortech.2016.03.096","article-title":"Activation of glycerol metabolism in Xanthomonas campestris by adaptive evolution to produce a high-transparency and low-viscosity xanthan gum from glycerol","volume":"211","author":"Wang","year":"2016","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0065","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.ijbiomac.2018.12.231","article-title":"Anti-diabetic activity evaluation of a polysaccharide extracted from Gynostemma pentaphyllum","volume":"126","author":"Wang","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0070","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.ijbiomac.2018.11.248","article-title":"Antibacterial activity of a polysaccharide produced from Chaetomium globosum CGMCC 6882","volume":"125","author":"Wang","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"issue":"7","key":"10.1016\/j.ijbiomac.2019.06.186_bb0075","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1016\/j.enconman.2010.12.004","article-title":"Overview on the current trends in biodiesel production","volume":"52","author":"Yusuf","year":"2011","journal-title":"Energ. Convers. Manage."},{"issue":"1","key":"10.1016\/j.ijbiomac.2019.06.186_bb0080","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.ejpe.2015.06.007","article-title":"The effects of alcohol to oil molar ratios and the type of alcohol on biodiesel production using transesterification process","volume":"25","author":"Musa","year":"2016","journal-title":"Egypt. J. Petrol."},{"issue":"11","key":"10.1016\/j.ijbiomac.2019.06.186_bb0085","doi-asserted-by":"crossref","first-page":"3933","DOI":"10.1021\/jf800602s","article-title":"Producing docosahexaenoic acid (DHA)-rich algae from biodiesel-derived crude glycerol: effects of impurities on DHA production and algal biomass composition","volume":"56","author":"Pyle","year":"2008","journal-title":"J. Agri. Food Chem."},{"issue":"2","key":"10.1016\/j.ijbiomac.2019.06.186_bb0090","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jbiotec.2006.09.015","article-title":"A simple method to monitor and control methanol feeding of Pichia pastoris fermentations using mid-IR spectroscopy","volume":"128","author":"Schenk","year":"2007","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0095","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.biortech.2018.01.008","article-title":"Utilization of methanol in crude glycerol to assist lipid production in non-sterilized fermentation from Trichosporon oleaginosus","volume":"253","author":"Chen","year":"2018","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.fuel.2017.07.070","article-title":"Lipid production from fed-batch fermentation of crude glycerol directed by the kinetic study of batch fermentations","volume":"209","author":"Chen","year":"2017","journal-title":"Fuel"},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0105","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.biortech.2013.10.031","article-title":"A novel osmotic pressure control fed-batch fermentation strategy for improvement of erythritol production by Yarrowia lipolytica from glycerol","volume":"151","author":"Yang","year":"2014","journal-title":"Bioresour. Technol."},{"issue":"2","key":"10.1016\/j.ijbiomac.2019.06.186_bb0110","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1139\/m89-047","article-title":"Effects of methanol on the growth of gastrointestinal anaerobes","volume":"35","author":"Caldwell","year":"1989","journal-title":"Can. J. Microbiol."},{"issue":"4","key":"10.1016\/j.ijbiomac.2019.06.186_bb0115","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1016\/j.biortech.2009.09.025","article-title":"Enhancement of cell viability and alkaline polygalacturonate lyase production by sorbitol co-feeding with methanol in Pichia pastoris fermentation","volume":"101","author":"Wang","year":"2010","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0120","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.carbpol.2015.12.065","article-title":"Efficient biosynthesis of polysaccharides chondroitin and heparosan by metabolically engineered Bacillus subtilis","volume":"140","author":"Jin","year":"2016","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2019.06.186_bb0125","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.carbpol.2017.12.009","article-title":"Biological activities and pharmaceutical applications of polysaccharide from natural resources: a review","volume":"183","author":"Yu","year":"2018","journal-title":"Carbohydr. Polym."},{"issue":"2","key":"10.1016\/j.ijbiomac.2019.06.186_bb0130","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.carbpol.2013.04.019","article-title":"Production, fractionation, characterization of extracellular polysaccharide from a newly isolated Trametes gibbosa and its hypoglycemic activity","volume":"96","author":"Ma","year":"2013","journal-title":"Carbohydr. Polym."},{"issue":"2","key":"10.1016\/j.ijbiomac.2019.06.186_bb0135","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.carbpol.2010.08.024","article-title":"Catalytic synthesis and antitumor activities of sulfated polysaccharide from Gynostemma pentaphyllum Makino","volume":"83","author":"Chen","year":"2011","journal-title":"Carbohydr. Polym."}],"container-title":["International Journal of Biological Macromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813019338863?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813019338863?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T16:42:50Z","timestamp":1568911370000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0141813019338863"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":27,"alternative-id":["S0141813019338863"],"URL":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2019.06.186","relation":{},"ISSN":["0141-8130"],"issn-type":[{"value":"0141-8130","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficient biosynthesis of anticancer polysaccharide by a mutant Chaetomium globosum ALE20 via non-sterilized fermentation","name":"articletitle","label":"Article Title"},{"value":"International Journal of Biological Macromolecules","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2019.06.186","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}