{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:12:12Z","timestamp":1786990332678,"version":"build-2736575974"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFA0902000"],"award-info":[{"award-number":["2018YFA0902000"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012246","name":"Priority Academic Program Development of Jiangsu Higher Education Institutions","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012246","id-type":"DOI","asserted-by":"publisher"}]},{"name":"\u201cDouble First-Class\u201d University project","award":["CPU2018GF\/GY16"],"award-info":[{"award-number":["CPU2018GF\/GY16"]}]},{"DOI":"10.13039\/501100002338","name":"Ministry of Education of China","doi-asserted-by":"publisher","award":["111-2-07"],"award-info":[{"award-number":["111-2-07"]}],"id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biological Macromolecules"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.ijbiomac.2020.06.120","type":"journal-article","created":{"date-parts":[[2020,6,15]],"date-time":"2020-06-15T01:56:30Z","timestamp":1592186190000},"page":"31-42","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"special_numbering":"C","title":["Characterization of a polysaccharide from Eupolyphaga sinensis walker and its effective antitumor activity via lymphocyte activation"],"prefix":"10.1016","volume":"162","author":[{"given":"Xin","family":"Xie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiran","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingman","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duiyue","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jialu","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangyuan","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baiyong","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changlin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0005","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s40264-014-0250-z","article-title":"Safety surveillance of traditional Chinese medicine: current and future","volume":"38","author":"Liu","year":"2015","journal-title":"Drug Saf."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0010","article-title":"Traditional Chinese medicine-guided dietary intervention for male youth undergoing drug detoxification: a randomized controlled trial","volume":"2019","author":"Zhang","year":"2019","journal-title":"Evidence-Based Complementary and Alternative Medicine\u202f: eCAM"},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0015","first-page":"1275","article-title":"New isocoumarins and alkaloid from Chinese insect medicine","volume":"83","author":"Jiang","year":"2012","journal-title":"Eupolyphaga sinensis Walker, Fitoterapia"},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0020","article-title":"Eupolyphaga sinensis Walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling","volume":"4","author":"Zhang","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0025","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.jep.2012.02.016","article-title":"Antitumor effects and chemical compositions of Eupolyphaga sinensis Walker ethanol extract","volume":"141","author":"Ge","year":"2012","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0030","article-title":"A bi-functional anti-thrombosis protein containing both direct-acting fibrin(ogen)olytic and plasminogen-activating activities","volume":"6","author":"Yang","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0035","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.jep.2010.08.019","article-title":"Effects of dahuangzhechong pills on cytokines and mitogen activated protein kinase activation in rats with hepatic fibrosis","volume":"132","author":"Cai","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0040","doi-asserted-by":"crossref","first-page":"5518","DOI":"10.1038\/srep05518","article-title":"Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling","volume":"4","author":"Zhang","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0045","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.foodres.2012.11.006","article-title":"Polysaccharides from green and black teas and their protective effect against murine sepsis","volume":"53","author":"Scoparo","year":"2013","journal-title":"Food Res. Int."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0050","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.carbpol.2014.12.023","article-title":"Activation of RAW264.7 macrophages by the polysaccharide from the roots of Actinidia eriantha and its molecular mechanisms","volume":"121","author":"Sun","year":"2015","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0055","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.carbpol.2017.06.024","article-title":"Enhanced antitumor activity of gemcitabine by polysaccharide-induced NK cell activation and immune cytotoxicity reduction in vitro\/vivo","volume":"173","author":"Xie","year":"2017","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0060","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.carbpol.2017.04.034","article-title":"Post-screening characterisation and in vivo evaluation of an anti-inflammatory polysaccharide fraction from Eucommia ulmoides","volume":"169","author":"Li","year":"2017","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0065","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1016\/j.carbpol.2017.07.041","article-title":"Structural analysis and immunomodulatory effect of polysaccharide from Atractylodis macrocephalae Koidz. on bovine lymphocytes","volume":"174","author":"Xu","year":"2017","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0070","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.carbpol.2016.09.073","article-title":"The polysaccharide and low molecular weight components of Opuntia ficus indica cladodes: structure and skin repairing properties","volume":"157","author":"Di Lorenzo","year":"2017","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0075","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0192-0561(94)00102-T","article-title":"Nitric oxide production by chicken macrophages activated by Acemannan, a complex carbohydrate extracted from Aloe vera","volume":"17","author":"Karaca","year":"1995","journal-title":"Int. J. Immunopharmacol."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0080","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1038\/nprot.2012.081","article-title":"Determining the polysaccharide composition of plant cell walls","volume":"7","author":"Pettolino","year":"2012","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0085","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.carbpol.2016.04.097","article-title":"Toll-like receptor 4-related immunostimulatory polysaccharides: primary structure, activity relationships, and possible interaction models","volume":"149","author":"Zhang","year":"2016","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0090","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/nrd2852","article-title":"From carbohydrate leads to glycomimetic drugs","volume":"8","author":"Ernst","year":"2009","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0095","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/S2468-1253(19)30178-5","article-title":"Management of patients with hepatocellular carcinoma and portal vein tumour thrombosis: comparing east and west","volume":"4","author":"Lu","year":"2019","journal-title":"The lancet. Gastroenterology & hepatology"},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0100","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.cell.2019.10.003","article-title":"Landscape and dynamics of single immune cells in hepatocellular carcinoma","volume":"179","author":"Zhang","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0105","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/S2468-1253(17)30104-8","article-title":"The role (if any) of chemotherapy in hepatocellular carcinoma","volume":"2","author":"El Dika","year":"2017","journal-title":"The lancet. Gastroenterology & hepatology"},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0110","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S0140-6736(18)30010-2","article-title":"Hepatocellular carcinoma","volume":"391","author":"Forner","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0115","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.suronc.2016.03.002","article-title":"Hepatocellular carcinoma: From diagnosis to treatment","volume":"25","author":"Grandhi","year":"2016","journal-title":"Surg. Oncol."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0120","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/s12276-018-0159-1","article-title":"Sorafenib resistance in hepatocarcinoma: role of hypoxia-inducible factors","volume":"50","author":"Mendez-Blanco","year":"2018","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0125","doi-asserted-by":"crossref","first-page":"5053","DOI":"10.2147\/OTT.S206517","article-title":"Monoclonal antibody AC10364 inhibits cell proliferation in 5-fluorouracil resistant hepatocellular carcinoma via apoptotic pathways","volume":"12","author":"Wu","year":"2019","journal-title":"OncoTargets and therapy"},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0130","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s12032-019-1323-8","article-title":"Caffeine enhances the anti-tumor effect of 5-fluorouracil via increasing the production of reactive oxygen species in hepatocellular carcinoma","volume":"36","author":"Wang","year":"2019","journal-title":"Med. Oncol."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0135","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.3892\/ol.2017.5624","article-title":"A polysaccharide component from Strongylocentrotus nudus eggs inhibited hepatocellular carcinoma in mice by activating T lymphocytes","volume":"13","author":"Zhang","year":"2017","journal-title":"Oncol. Lett."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0140","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/j.carbpol.2012.09.079","article-title":"Structural characteristics and antioxidant activities of polysaccharides from longan seed","volume":"92","author":"Jiang","year":"2013","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0145","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.carres.2012.09.006","article-title":"Structural analysis of immunostimulating sulfated polysaccharides from Ulva pertusa","volume":"361","author":"Tabarsa","year":"2012","journal-title":"Carbohydr. Res."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0150","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.bcp.2014.02.024","article-title":"The anti-lung cancer activity of SEP is mediated by the activation and cytotoxicity of NK cells via TLR2\/4 in vivo","volume":"89","author":"Ke","year":"2014","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0155","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.carbpol.2019.04.057","article-title":"Studies on structural properties and immune-enhancing activities of glycomannans from Schizophyllum commune","volume":"218","author":"Yelithao","year":"2019","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0160","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.carbpol.2012.05.095","article-title":"Structural investigation of an extracellular polysaccharide produced by the cariogenic bacterium Streptococcus mutans strain UA159","volume":"90","author":"Li","year":"2012","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0165","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/j.etap.2014.04.010","article-title":"Eupolyphaga sinensis Walker inhibits human chronic myeloid leukemia cell K562 growth by inducing G2-M phase cell cycle arrest and targeting EGFR signaling pathway and in S180 tumor-bearing mice","volume":"37","author":"Dai","year":"2014","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0170","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.carbpol.2015.05.079","article-title":"Structure-function relationships of immunostimulatory polysaccharides: a review","volume":"132","author":"Ferreira","year":"2015","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0175","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.carbpol.2019.03.014","article-title":"Purification, characterization and immunomodulatory activity of fructans from Polygonatum odoratum and P. cyrtonema","volume":"214","author":"Zhao","year":"2019","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0180","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.carbpol.2019.05.006","article-title":"Bifidobacterium bifidum presents on the cell surface a complex mixture of glucans and galactans with different immunological properties","volume":"218","author":"Speciale","year":"2019","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0185","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1016\/j.carres.2010.04.004","article-title":"Isolation of phosphorylated polysaccharides from algae: the immunostimulatory principle of Chlorella pyrenoidosa","volume":"345","author":"Suarez","year":"2010","journal-title":"Carbohydr. Res."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0190","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00262-019-02451-4","article-title":"B7H4 expression in tumor cells impairs CD8 T cell responses and tumor immunity","volume":"69","author":"Zhou","year":"2019","journal-title":"Cancer Immunol. Immunother.\u202f: CII"},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0195","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.carbpol.2018.08.096","article-title":"A heteropolysaccharide from Saccharina japonica with immunomodulatory effect on RAW 264.7 cells","volume":"201","author":"Geng","year":"2018","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2019.115314","article-title":"Structural characterisation and immunomodulatory activity of polysaccharides from white asparagus skin","volume":"227","author":"Wang","year":"2020","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0205","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S1567-5769(03)00118-8","article-title":"Toll-like receptor-mediated activation of B cells and macrophages by polysaccharide isolated from cell culture of Acanthopanax senticosus","volume":"3","author":"Han","year":"2003","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0210","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1248\/bpb.30.1384","article-title":"Blocking effect of anti-Dectin-1 antibodies on the anti-tumor activity of 1,3-beta-glucan and the binding of Dectin-1 to 1,3-beta-glucan","volume":"30","author":"Ikeda","year":"2007","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0215","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1016\/j.intimp.2006.07.028","article-title":"Mechanism of macrophage activation by (1,4)-alpha-D-glucan isolated from Tinospora cordifolia","volume":"6","author":"Nair","year":"2006","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2019.112011","article-title":"Binding of the polysaccharide from Acanthopanax giraldii harms to toll-like receptor 4 activates macrophages","volume":"241","author":"Li","year":"2019","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0225","doi-asserted-by":"crossref","first-page":"5815","DOI":"10.1016\/j.vaccine.2015.09.021","article-title":"Molecular shape and immunogenicity of meningococcal polysaccharide group a conjugate vaccine","volume":"33","author":"Xu","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0230","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.phrs.2003.12.002","article-title":"In vivo antitumor and immunomodulation activities of different molecular weight lambda-carrageenans from Chondrus ocellatus","volume":"50","author":"Zhou","year":"2004","journal-title":"Pharmacol. Res."},{"issue":"2","key":"10.1016\/j.ijbiomac.2020.06.120_bb0235","first-page":"1","article-title":"Exhaustion and senescence: two crucial dysfunctional states of T cells in the tumor microenvironment","volume":"17","author":"Zhao","year":"2019","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0240","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/BF02986610","article-title":"Importance of CD4+ helper T-cells in antitumor immunity","volume":"77","author":"Shiku","year":"2003","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0245","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1038\/s41423-019-0224-2","article-title":"Targeting natural killer cells in solid tumors","volume":"16","author":"Habif","year":"2019","journal-title":"Cell Mol Immunol"},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0250","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1159\/000325465","article-title":"Natural killer cells and solid tumors","volume":"3","author":"Stojanovic","year":"2011","journal-title":"J Innate Immun"},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0255","doi-asserted-by":"crossref","first-page":"3324","DOI":"10.1002\/eji.201546000","article-title":"IL-2 and IL-15 regulate CD8+ memory T-cell differentiation but are dispensable for protective recall responses","volume":"45","author":"Mathieu","year":"2015","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.ijbiomac.2020.06.120_bb0260","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0065-2776(07)96002-2","article-title":"Regulation of interferon-gamma during innate and adaptive immune responses","volume":"96","author":"Schoenborn","year":"2007","journal-title":"Adv. Immunol."}],"container-title":["International Journal of Biological Macromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813020335443?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813020335443?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T08:07:20Z","timestamp":1758874040000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0141813020335443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":52,"alternative-id":["S0141813020335443"],"URL":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2020.06.120","relation":{},"ISSN":["0141-8130"],"issn-type":[{"value":"0141-8130","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of a polysaccharide from Eupolyphaga sinensis walker and its effective antitumor activity via lymphocyte activation","name":"articletitle","label":"Article Title"},{"value":"International Journal of Biological Macromolecules","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2020.06.120","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}