{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T21:18:44Z","timestamp":1788297524140,"version":"build-2803163510"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biological Macromolecules"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.ijbiomac.2020.07.274","type":"journal-article","created":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T21:32:49Z","timestamp":1596576769000},"page":"2197-2203","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"special_numbering":"C","title":["Overview of novel strategies for the delivery of anthracyclines to cancer cells by liposomal and polymeric nanoformulations"],"prefix":"10.1016","volume":"164","author":[{"given":"Mehran","family":"Alavi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajender S.","family":"Varma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biomaterials.2019.04.027","article-title":"Advances in drug delivery for post-surgical cancer treatment","volume":"219","author":"Bu","year":"2019","journal-title":"Biomaterials"},{"issue":"13","key":"10.1016\/j.ijbiomac.2020.07.274_bb0010","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1080\/14656566.2019.1621292","article-title":"Topoisomerase II inhibitors in AML: past, present, and future","volume":"20","author":"Economides","year":"2019","journal-title":"Expert. Opin. Pharmacother."},{"issue":"2","key":"10.1016\/j.ijbiomac.2020.07.274_bb0015","doi-asserted-by":"crossref","first-page":"122","DOI":"10.2174\/1568009616666160216125833","article-title":"Current development of ROS-modulating agents as novel antitumor therapy","volume":"17","author":"Wang","year":"2017","journal-title":"Curr. Cancer Drug Targets"},{"issue":"12","key":"10.1016\/j.ijbiomac.2020.07.274_bb0020","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1016\/j.bcp.2012.02.026","article-title":"Activation of DNA damage response pathways as a consequence of anthracycline-DNA adduct formation","volume":"83","author":"Forrest","year":"2012","journal-title":"Biochem. Pharmacol."},{"issue":"15","key":"10.1016\/j.ijbiomac.2020.07.274_bb0025","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.2174\/0929867323666161214120355","article-title":"Topoisomerases and anthracyclines: recent advances and perspectives in anticancer therapy and prevention of cardiotoxicity","volume":"24","author":"Mordente","year":"2017","journal-title":"Curr. Med. Chem."},{"issue":"4","key":"10.1016\/j.ijbiomac.2020.07.274_bb0030","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0928-0987(00)00114-7","article-title":"Multidrug resistance (MDR) in cancer: mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs","volume":"11","author":"Krishna","year":"2000","journal-title":"Eur. J. Pharm. Sci."},{"issue":"7","key":"10.1016\/j.ijbiomac.2020.07.274_bb0035","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.3390\/ijms18071396","article-title":"The impact of melatonin on colon cancer cells\u2019 resistance to doxorubicin in an in vitro study","volume":"18","author":"Fic","year":"2017","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.ijbiomac.2020.07.274_bb0040","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.canlet.2015.10.010","article-title":"Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: a review of the past decade","volume":"370","author":"Chen","year":"2016","journal-title":"Cancer Lett."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0045","series-title":"Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy","first-page":"1","article-title":"Efflux transporters in cancer resistance: molecular and functional characterization of P-glycoprotein","author":"Turner","year":"2020"},{"issue":"6","key":"10.1016\/j.ijbiomac.2020.07.274_bb0050","doi-asserted-by":"crossref","first-page":"721","DOI":"10.2174\/1871520615666150407155319","article-title":"The use of anthracyclines for therapy of CNS tumors","volume":"15","author":"Ros","year":"2015","journal-title":"Anti Cancer Agents Med. Chem."},{"issue":"19","key":"10.1016\/j.ijbiomac.2020.07.274_bb0055","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1002\/cphc.201900551","article-title":"Emerging two-dimensional nanomaterials for cancer therapy","volume":"20","author":"Guo","year":"2019","journal-title":"ChemPhysChem"},{"issue":"34","key":"10.1016\/j.ijbiomac.2020.07.274_bb0060","doi-asserted-by":"crossref","first-page":"4224","DOI":"10.2174\/0929867324666170830113755","article-title":"The clinical translation of organic nanomaterials for cancer therapy: a focus on polymeric nanoparticles, micelles, liposomes and exosomes","volume":"25","author":"Palazzolo","year":"2018","journal-title":"Curr. Med. Chem."},{"issue":"11","key":"10.1016\/j.ijbiomac.2020.07.274_bb0065","doi-asserted-by":"crossref","first-page":"094","DOI":"10.7324\/JAPS.2016.601115","article-title":"Characterization of Ag nanoparticles biosynthesized by Bacillus sp. HAI4 in different conditions and their antibacterial effects","volume":"6","author":"Taran","year":"2016","journal-title":"Journal of Applied Pharmaceutical Science"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0070","first-page":"351","article-title":"Biological synthesis of copper nanoparticles by using Halomonas elongata IBRC-M 10214","volume":"67","author":"Taran","year":"2016","journal-title":"Industria Textila"},{"issue":"1","key":"10.1016\/j.ijbiomac.2020.07.274_bb0075","doi-asserted-by":"crossref","first-page":"25","DOI":"10.5101\/nbe.v10i1.p25-33","article-title":"Effect of incubation time, CuSO4 and glucose concentrations on biosynthesis of copper oxide (CuO) nanoparticles with rectangular shape and antibacterial activity: Taguchi method approach","volume":"10","author":"Rad","year":"2018","journal-title":"Nano Biomed Eng"},{"issue":"47","key":"10.1016\/j.ijbiomac.2020.07.274_bb0080","doi-asserted-by":"crossref","first-page":"10995","DOI":"10.1002\/chem.201901841","article-title":"Inherent chemotherapeutic anti-cancer effects of low-dimensional nanomaterials","volume":"25","author":"Fu","year":"2019","journal-title":"Chem Eur J"},{"issue":"6 Suppl 13","key":"10.1016\/j.ijbiomac.2020.07.274_bb0085","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1053\/j.seminoncol.2004.08.001","article-title":"Advantages of liposomal delivery systems for anthracyclines","volume":"31","author":"Allen","year":"2004","journal-title":"Semin. Oncol."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0090","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/978-3-030-01881-8_7","article-title":"Engineering Streptomyces peucetius for doxorubicin and daunorubicin biosynthesis","author":"Shrestha","year":"2019","journal-title":"Pharmaceuticals From Microbes"},{"issue":"1","key":"10.1016\/j.ijbiomac.2020.07.274_bb0095","doi-asserted-by":"crossref","first-page":"3","DOI":"10.15171\/apb.2017.002","article-title":"Application of various types of liposomes in drug delivery systems","volume":"7","author":"Alavi","year":"2017","journal-title":"Advanced Pharmaceutical Bulletin"},{"issue":"1","key":"10.1016\/j.ijbiomac.2020.07.274_bb0100","doi-asserted-by":"crossref","DOI":"10.1515\/dmpt-2018-0032","article-title":"Passive and active targeting in cancer therapy by liposomes and lipid nanoparticles","volume":"34","author":"Alavi","year":"2019","journal-title":"Drug Metabolism and Personalized Therapy"},{"issue":"2","key":"10.1016\/j.ijbiomac.2020.07.274_bb0105","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.bmcl.2018.11.014","article-title":"Synthesis and anti-neuroinflammatory activity of N-heterocyclic analogs based on natural biphenyl-neolignan honokiol","volume":"29","author":"Yuan","year":"2019","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0110","series-title":"Magnolia extract containing compositions","author":"Faller","year":"2017"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0115","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.phymed.2018.06.004","article-title":"Potent anti-inflammatory effects of honokiol in human fetal membranes and myometrium","volume":"49","author":"Wijesuriya","year":"2018","journal-title":"Phytomedicine"},{"issue":"2","key":"10.1016\/j.ijbiomac.2020.07.274_bb0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbcan.2020.188338","article-title":"The emerging role of paraptosis in tumor cell biology: perspectives for cancer prevention and therapy with natural compounds","volume":"1873","author":"Fontana","year":"2020","journal-title":"Biochimica et Biophysica Acta (BBA)-Reviews on Cancer"},{"issue":"1","key":"10.1016\/j.ijbiomac.2020.07.274_bb0125","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1021\/acsinfecdis.9b00190","article-title":"A bisphenolic honokiol analog outcompetes oral antimicrobial agent cetylpyridinium chloride via a membrane-associated mechanism","volume":"6","author":"Ochoa","year":"2019","journal-title":"ACS Infectious Diseases"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0130","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.biopha.2018.08.054","article-title":"Honokiol: an anticancer lignan","volume":"107","author":"Rauf","year":"2018","journal-title":"Biomed. Pharmacother."},{"issue":"4","key":"10.1016\/j.ijbiomac.2020.07.274_bb0135","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1111\/cbdd.12880","article-title":"Synthesis of honokiol analogues and evaluation of their modulating action on VEGF protein secretion and telomerase-related gene expressions","volume":"89","author":"S\u00e1nchez-Peris","year":"2017","journal-title":"Chem. Biol. Drug Des."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2020.119793","article-title":"AKT activation by SC79 to transiently re-open pathological blood brain barrier for improved functionalized nanoparticles therapy of glioblastoma","volume":"237","author":"Wen","year":"2020","journal-title":"Biomaterials"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0145","doi-asserted-by":"crossref","first-page":"946","DOI":"10.3389\/fphar.2019.00946","article-title":"Iron (II) polypyridyl complexes as anti-glioblastoma agents to overcome the blood-brain barrier and inhibit cell proliferation by regulating p53 and 4E-BP1 pathways","volume":"10","author":"Zhu","year":"2019","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0150","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ejps.2017.06.002","article-title":"Antitumor efficacy of Lf modified daunorubicin plus honokiol liposomes in treatment of brain glioma","volume":"106","author":"Liu","year":"2017","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0155","doi-asserted-by":"crossref","first-page":"3819","DOI":"10.2147\/IJN.S139450","article-title":"CPX-351: a nanoscale liposomal co-formulation of daunorubicin and cytarabine with unique biodistribution and tumor cell uptake properties","volume":"14","author":"Mayer","year":"2019","journal-title":"Int. J. Nanomedicine"},{"issue":"1","key":"10.1016\/j.ijbiomac.2020.07.274_bb0160","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s00280-017-3484-5","article-title":"Persistent cytarabine and daunorubicin exposure after administration of novel liposomal formulation CPX-351: population pharmacokinetic assessment","volume":"81","author":"Nikanjam","year":"2018","journal-title":"Cancer Chemother. Pharmacol."},{"issue":"sup1","key":"10.1016\/j.ijbiomac.2020.07.274_bb0165","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1080\/21691401.2018.1433187","article-title":"Octreotide-modified liposomes containing daunorubicin and dihydroartemisinin for treatment of invasive breast cancer","volume":"46","author":"Ju","year":"2018","journal-title":"Artificial Cells, Nanomedicine, and Biotechnology"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0170","doi-asserted-by":"crossref","first-page":"4071","DOI":"10.2147\/IJN.S194304","article-title":"Inhibition of tumor metastasis by targeted daunorubicin and dioscin codelivery liposomes modified with PFV for the treatment of non-small-cell lung cancer","volume":"14","author":"Wang","year":"2019","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0175","first-page":"1","article-title":"Topical delivery of growth factors and metal\/metal oxide nanoparticles to infected wounds by polymeric nanoparticles: an overview","author":"Alavi","year":"2020","journal-title":"Expert Rev. Anti-Infect. Ther."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0180","series-title":"Nanotechnology in Skin, Soft Tissue, and Bone Infections","first-page":"169","article-title":"Applications of chitosan and nanochitosan in formulation of novel antibacterial and wound healing agents","author":"Alavi","year":"2020"},{"issue":"2","key":"10.1016\/j.ijbiomac.2020.07.274_bb0185","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1002\/wnan.1364","article-title":"Polymeric nanoparticles: the future of nanomedicine","volume":"8","author":"Banik","year":"2016","journal-title":"WIREs Nanomedicine and Nanobiotechnology"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0190","first-page":"1","article-title":"PEGylated polylactide (PLA) and poly (lactic-co-glycolic acid)(PLGA) copolymers for the design of drug delivery systems","author":"Perinelli","year":"2019","journal-title":"Journal of Pharmaceutical Investigation"},{"issue":"1","key":"10.1016\/j.ijbiomac.2020.07.274_bb0195","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1515\/epoly-2019-0013","article-title":"Modifications of microcrystalline cellulose (MCC), nanofibrillated cellulose (NFC), and nanocrystalline cellulose (NCC) for antimicrobial and wound healing applications","volume":"19","author":"Alavi","year":"2019","journal-title":"e-Polymers"},{"issue":"21","key":"10.1016\/j.ijbiomac.2020.07.274_bb0200","doi-asserted-by":"crossref","first-page":"8669","DOI":"10.1007\/s00253-019-10126-4","article-title":"Recent progress in nanoformulations of silver nanoparticles with cellulose, chitosan, and alginic acid biopolymers for antibacterial applications","volume":"103","author":"Alavi","year":"2019","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0205","first-page":"1","article-title":"Antimicrobial and wound treatment aspects of micro-and nanoformulations of carboxymethyl, dialdehyde, and TEMPO-oxidized derivatives of cellulose: recent advances","author":"Alavi","year":"2020","journal-title":"Macromol. Biosci."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0210","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.ijbiomac.2019.01.142","article-title":"Daunorubicin oral bioavailability enhancement by surface coated natural biodegradable macromolecule chitosan based polymeric nanoparticles","volume":"128","author":"Ahmad","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.reactfunctpolym.2019.104332","article-title":"Daunorubicin-silsesquioxane conjugates (POSS-DAU) for theranostic drug delivery system: characterization, biocompatibility and drug release study","volume":"143","author":"Rozga-Wijas","year":"2019","journal-title":"React. Funct. Polym."},{"issue":"8","key":"10.1016\/j.ijbiomac.2020.07.274_bb0220","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1166\/jbn.2016.2278","article-title":"A pH-sensitive nanosystem based on carboxymethyl chitosan for tumor-targeted delivery of daunorubicin","volume":"12","author":"Zhang","year":"2016","journal-title":"J. Biomed. Nanotechnol."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0225","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.jconrel.2018.12.042","article-title":"Near infrared light-triggered nanoparticles using singlet oxygen photocleavage for drug delivery systems","volume":"294","author":"Dariva","year":"2019","journal-title":"J. Control. Release"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0230","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.biomaterials.2015.10.027","article-title":"Doxorubicin encapsulated in stealth liposomes conferred with light-triggered drug release","volume":"75","author":"Luo","year":"2016","journal-title":"Biomaterials"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0235","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jconrel.2015.11.021","article-title":"An integrated assessment of morphology, size, and complement activation of the PEGylated liposomal doxorubicin products Doxil\u00ae, Caelyx\u00ae, DOXOrubicin, and SinaDoxosome","volume":"221","author":"Wibroe","year":"2016","journal-title":"J. Control. Release"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0240","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ejphar.2019.01.028","article-title":"Galbanic acid potentiates TRAIL induced apoptosis in resistant non-small cell lung cancer cells via inhibition of MDR1 and activation of caspases and DR5","volume":"847","author":"Kim","year":"2019","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.ijbiomac.2020.07.274_bb0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-019-45974-7","article-title":"Liposomal formulation of galbanic acid improved therapeutic efficacy of pegylated liposomal doxorubicin in mouse colon carcinoma","volume":"9","author":"Nik","year":"2019","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.ijbiomac.2020.07.274_bb0250","doi-asserted-by":"crossref","first-page":"547","DOI":"10.3390\/nano9040547","article-title":"Biodegradable redox-sensitive star polymer nanomicelles for enhancing doxorubicin delivery","volume":"9","author":"Li","year":"2019","journal-title":"Nanomaterials"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0255","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.biomaterials.2017.07.004","article-title":"Localised delivery of doxorubicin to prostate cancer cells through a PSMA-targeted hyperbranched polymer theranostic","volume":"141","author":"Pearce","year":"2017","journal-title":"Biomaterials"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0260","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.actbio.2018.11.050","article-title":"Stimuli-responsive polymer-doxorubicin conjugate: antitumor mechanism and potential as nano-prodrug","volume":"84","author":"Chen","year":"2019","journal-title":"Acta Biomater."},{"issue":"1","key":"10.1016\/j.ijbiomac.2020.07.274_bb0265","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s40005-016-0293-5","article-title":"Polymer-surfactant nanoparticles for improving oral bioavailability of doxorubicin","volume":"47","author":"Kirtane","year":"2017","journal-title":"Journal of Pharmaceutical Investigation"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0270","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jddst.2018.03.008","article-title":"Influence of supramolecular layer-crosslinked structure on stability of dual pH-responsive polymer nanoparticles for doxorubicin delivery","volume":"45","author":"Feng","year":"2018","journal-title":"Journal of Drug Delivery Science and Technology"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0275","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.actbio.2018.12.020","article-title":"DOX loaded aggregation-induced emission active polymeric nanoparticles as a fluorescence resonance energy transfer traceable drug delivery system for self-indicating cancer therapy","volume":"85","author":"Wang","year":"2019","journal-title":"Acta Biomater."},{"issue":"1","key":"10.1016\/j.ijbiomac.2020.07.274_bb0280","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.ijpharm.2017.03.034","article-title":"Targeted delivery of epirubicin to tumor-associated macrophages by sialic acid-cholesterol conjugate modified liposomes with improved antitumor activity","volume":"523","author":"Zhou","year":"2017","journal-title":"Int. J. Pharm."},{"issue":"3","key":"10.1016\/j.ijbiomac.2020.07.274_bb0285","doi-asserted-by":"crossref","first-page":"339","DOI":"10.15171\/apb.2017.041","article-title":"The different mechanisms of cancer drug resistance: a brief review","volume":"7","author":"Mansoori","year":"2017","journal-title":"Advanced Pharmaceutical Bulletin"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0290","doi-asserted-by":"crossref","first-page":"4163","DOI":"10.2147\/IJN.S133194","article-title":"The use of functional epirubicin liposomes to induce programmed death in refractory breast cancer","volume":"12","author":"Liu","year":"2017","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0295","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2019.118806","article-title":"Co-delivery of epirubicin and paclitaxel using an estrone-targeted PEGylated liposomal nanoparticle for breast cancer","volume":"573","author":"Tang","year":"2020","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0300","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.jconrel.2017.04.033","article-title":"cRGD peptide-installed epirubicin-loaded polymeric micelles for effective targeted therapy against brain tumors","volume":"258","author":"Quader","year":"2017","journal-title":"J. Control. Release"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0305","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.jconrel.2018.10.035","article-title":"Epirubicin-loaded polymeric micelles effectively treat axillary lymph nodes metastasis of breast cancer through selective accumulation and pH-triggered drug release","volume":"292","author":"Chida","year":"2018","journal-title":"J. Control. Release"},{"issue":"546","key":"10.1016\/j.ijbiomac.2020.07.274_bb0310","article-title":"Function of epirubicin-conjugated polymeric micelles in sonodynamic therapy","volume":"10","author":"Takemae","year":"2019","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0315","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.jconrel.2015.10.056","article-title":"Formulation and optimization of idarubicin thermosensitive liposomes provides ultrafast triggered release at mild hyperthermia and improves tumor response","volume":"220","author":"Lu","year":"2015","journal-title":"J. Control. Release"},{"issue":"1","key":"10.1016\/j.ijbiomac.2020.07.274_bb0320","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.ijpharm.2016.04.031","article-title":"Aptamer targeting of the elongation factor 1A impairs hepatocarcinoma cells viability and potentiates bortezomib and idarubicin effects","volume":"506","author":"Scaggiante","year":"2016","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0325","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jddst.2018.07.017","article-title":"Specific delivery of idarubicin to HER2-positive breast cancerous cell line by trastuzumab-conjugated liposomes","volume":"47","author":"Amin","year":"2018","journal-title":"Journal of Drug Delivery Science and Technology"},{"issue":"1","key":"10.1016\/j.ijbiomac.2020.07.274_bb0330","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ijpharm.2014.07.048","article-title":"Polyester-idarubicin nanoparticles and a polymer-photosensitizer complex as potential drug formulations for cell-mediated drug delivery","volume":"474","author":"Blaudszun","year":"2014","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0335","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.colsurfb.2015.03.014","article-title":"Cyclodextrin-based star polymers as a versatile platform for nanochemotherapeutics: enhanced entrapment and uptake of idarubicin","volume":"129","author":"Nafee","year":"2015","journal-title":"Colloids Surf. B: Biointerfaces"},{"key":"10.1016\/j.ijbiomac.2020.07.274_bb0340","doi-asserted-by":"crossref","first-page":"543","DOI":"10.2147\/IJN.S190027","article-title":"Idarubicin-loaded methoxy poly(ethylene glycol)-b-poly(l-lactide-co-glycolide) nanoparticles for enhancing cellular uptake and promoting antileukemia activity","volume":"14","author":"Liang","year":"2019","journal-title":"Int. J. Nanomedicine"}],"container-title":["International Journal of Biological Macromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813020340381?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813020340381?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T21:00:32Z","timestamp":1788296432000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0141813020340381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":68,"alternative-id":["S0141813020340381"],"URL":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2020.07.274","relation":{},"ISSN":["0141-8130"],"issn-type":[{"value":"0141-8130","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Overview of novel strategies for the delivery of anthracyclines to cancer cells by liposomal and polymeric nanoformulations","name":"articletitle","label":"Article Title"},{"value":"International Journal of Biological Macromolecules","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2020.07.274","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}