{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:17:42Z","timestamp":1790417862404,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100016305","name":"First Affiliated Hospital of Zhengzhou University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100016305","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002383","name":"King Saud University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002383","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100016305","name":"First Affiliated Hospital of Zhengzhou University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100016305","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biological Macromolecules"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.ijbiomac.2020.12.037","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T17:12:27Z","timestamp":1607620347000},"page":"198-207","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["In situ decorated Au NPs on chitosan-encapsulated Fe3O4-NH2 NPs as magnetic nanocomposite: Investigation of its anti-colon carcinoma, anti-gastric cancer and anti-pancreatic cancer"],"prefix":"10.1016","volume":"171","author":[{"given":"Xinjie","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hesham S.","family":"Almoallim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingli","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sulaiman Ali","family":"Alharbi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongli","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0005","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1038\/s41416-018-0178-7","volume":"119","author":"Juul","year":"2018","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0010","doi-asserted-by":"crossref","first-page":"231","DOI":"10.3399\/bjgp11X572427","article-title":"The diagnostic value of symptoms for colorectal cancer in primary care: a systematic review","volume":"61","author":"Astin","year":"2011","journal-title":"Br. J. Gen. Pract."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0015","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1016\/S0140-6736(10)60353-4","article-title":"Colorectal cancer","volume":"375","author":"Cunningham","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0020","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1056\/NEJMsr1606602","article-title":"Body fatness and cancer\u2014viewpoint of the IARC Working Group","volume":"375","author":"Lauby-Secretan","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0025","first-page":"308","article-title":"Markers of resistance to anti-EGFR therapy in colorectal cancer","volume":"4","author":"Shaib","year":"2013","journal-title":"J. Gastrointest. Oncol."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0030","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1007\/BF03353627","volume":"2","author":"Raut","year":"2010","journal-title":"Nano-Micro Letters"},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0035","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.coche.2011.12.002","volume":"1","author":"Varma","year":"2012","journal-title":"Cur. Opin. Chem. Eng."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0040","author":"Adhikari","year":"2018","journal-title":"Int. J. Biomaterials"},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0045","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/S0002-9343(00)00412-5","volume":"108","author":"McCord","year":"2000","journal-title":"Am. J. Med."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0050","first-page":"29","volume":"7","author":"Rao","year":"2006","journal-title":"Adv. Pharm. Toxic."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0055","doi-asserted-by":"crossref","first-page":"4127","DOI":"10.1016\/j.bmcl.2006.04.077","volume":"16","author":"Zheng","year":"2006","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0060","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1351\/PAC-CON-08-11-15","volume":"81","author":"Wang","year":"2009","journal-title":"Pure Appl. Chem."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0065","doi-asserted-by":"crossref","first-page":"66","DOI":"10.3998\/ark.5550190.0005.910","volume":"2004","author":"Yin","year":"2004","journal-title":"Arkivoc"},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.carbpol.2015.04.040","volume":"129","author":"Jiang","year":"2015","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.12.037_rf0075","doi-asserted-by":"crossref","first-page":"41551","DOI":"10.1039\/C6RA02123A","volume":"6","author":"Bagherzadeh","year":"2016","journal-title":"RSC Adv."},{"key":"10.1016\/j.ijbiomac.2020.12.037_rf0080","doi-asserted-by":"crossref","first-page":"4329","DOI":"10.1002\/anie.200605216","volume":"46","author":"Dalaigh","year":"2007","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.ijbiomac.2020.12.037_rf0085","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.jcat.2018.07.008","volume":"365","author":"Veisi","year":"2018","journal-title":"J. Catal."},{"key":"10.1016\/j.ijbiomac.2020.12.037_rf0090","doi-asserted-by":"crossref","first-page":"110465","DOI":"10.1016\/j.colsurfb.2019.110465","volume":"184","author":"El-Sayed","year":"2019","journal-title":"Colloids Surf. B: Biointerfaces"},{"key":"10.1016\/j.ijbiomac.2020.12.037_rf0095","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ijbiomac.2014.05.047","volume":"69","author":"Youssef","year":"2014","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2020.12.037_rf0100","doi-asserted-by":"crossref","first-page":"116234","DOI":"10.1016\/j.carbpol.2020.116234","volume":"239","author":"El-Sayed","year":"2020","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.12.037_rf0105","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.carbpol.2018.05.065","volume":"196","author":"Youssef","year":"2018","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0085","doi-asserted-by":"crossref","first-page":"3428","DOI":"10.1002\/anie.200905684","volume":"49","author":"Shylesh","year":"2010","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0090","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1039\/C7NJ02513K","volume":"42","author":"Mirfakhraei","year":"2018","journal-title":"New J. Chem."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0095","first-page":"365","volume":"2","author":"Zhu","year":"2010","journal-title":"Chem. Cat. Chem."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0100","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.nantod.2010.08.008","volume":"5","author":"Lim","year":"2010","journal-title":"Nano Today"},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0105","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1002\/(SICI)1096-9918(199807)26:8<549::AID-SIA396>3.0.CO;2-Q","volume":"26","author":"McCafferty","year":"1998","journal-title":"Surf. Interface Anal."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0110","doi-asserted-by":"crossref","first-page":"7350","DOI":"10.1039\/c1jm10535c","volume":"21","author":"Riente","year":"2011","journal-title":"J. Mater. Chem."},{"key":"10.1016\/j.ijbiomac.2020.12.037_rf0140","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.molcata.2011.10.022","volume":"352","author":"Senapati","year":"2012","journal-title":"J. Mol. Catal. A Chem."},{"key":"10.1016\/j.ijbiomac.2020.12.037_rf0145","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1002\/elan.201800158","volume":"30","author":"Baghayeri","year":"2018","journal-title":"Electroanalysis"},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0120","doi-asserted-by":"crossref","first-page":"e5136","DOI":"10.1002\/aoc.5136","volume":"34","author":"Mohammadi","year":"2020","journal-title":"Appl. Organomet. Chem."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0125","doi-asserted-by":"crossref","first-page":"118965","DOI":"10.1016\/j.ica.2019.118965","volume":"495","author":"Gholinejad","year":"2019","journal-title":"Inorg. Chim. Acta"},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0130","doi-asserted-by":"crossref","first-page":"e4961","DOI":"10.1002\/aoc.4961","volume":"33","author":"Zangeneh","year":"2019","journal-title":"Appl. Organomet. Chem."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0135","first-page":"325","article-title":"Herbal treatment for the ovarian cancer","volume":"3","author":"Shaneza","year":"2018","journal-title":"SGVU J. Pharmac. Res. Edu."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0140","doi-asserted-by":"crossref","first-page":"e5015","DOI":"10.1002\/aoc.5015","volume":"33","author":"Zhaleh","year":"2019","journal-title":"Appl. Organomet. Chem."},{"key":"10.1016\/j.ijbiomac.2020.12.037_bb0145","doi-asserted-by":"crossref","first-page":"e5216","DOI":"10.1002\/aoc.5216","volume":"33","author":"Zangeneh","year":"2019","journal-title":"Appl. Organomet. Chem."}],"container-title":["International Journal of Biological Macromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014181302035193X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014181302035193X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T08:30:41Z","timestamp":1758875441000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S014181302035193X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":35,"alternative-id":["S014181302035193X"],"URL":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2020.12.037","relation":{},"ISSN":["0141-8130"],"issn-type":[{"value":"0141-8130","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In situ decorated Au NPs on chitosan-encapsulated Fe3O4-NH2 NPs as magnetic nanocomposite: Investigation of its anti-colon carcinoma, anti-gastric cancer and anti-pancreatic cancer","name":"articletitle","label":"Article Title"},{"value":"International Journal of Biological Macromolecules","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2020.12.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}