{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T12:22:25Z","timestamp":1778761345203,"version":"3.51.4"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003345","name":"Chinese Academy of Meteorological Sciences","doi-asserted-by":"publisher","award":["2019-12M-5-032"],"award-info":[{"award-number":["2019-12M-5-032"]}],"id":[{"id":"10.13039\/501100003345","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012542","name":"Sichuan Province Science and Technology Support Program","doi-asserted-by":"publisher","award":["2022YFS0598"],"award-info":[{"award-number":["2022YFS0598"]}],"id":[{"id":"10.13039\/100012542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012542","name":"Sichuan Province Science and Technology Support Program","doi-asserted-by":"publisher","award":["2023NSFSC0036"],"award-info":[{"award-number":["2023NSFSC0036"]}],"id":[{"id":"10.13039\/100012542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People's Republic of China","doi-asserted-by":"publisher","award":["ZYGX2022J023"],"award-info":[{"award-number":["ZYGX2022J023"]}],"id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82000913"],"award-info":[{"award-number":["82000913"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82101153"],"award-info":[{"award-number":["82101153"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82121003"],"award-info":[{"award-number":["82121003"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82330030"],"award-info":[{"award-number":["82330030"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biological Macromolecules"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.ijbiomac.2023.128570","type":"journal-article","created":{"date-parts":[[2023,12,12]],"date-time":"2023-12-12T12:48:52Z","timestamp":1702385332000},"page":"128570","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"P1","title":["Frameshift variants in the C-terminal of CTNNB1 cause familial exudative vitreoretinopathy by AXIN1-mediated ubiquitin-proteasome degradation condensation"],"prefix":"10.1016","volume":"258","author":[{"given":"Yining","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunqi","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erkuan","family":"Dai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenglin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shujin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ijbiomac.2023.128570_bb0005","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/0002-9394(69)91237-9","article-title":"Familial exudative vitreoretinopathy","volume":"68","author":"Criswick","year":"1969","journal-title":"Am J. Ophthalmol."},{"issue":"1","key":"10.1016\/j.ijbiomac.2023.128570_bb0010","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1136\/bjophthalmol-2019-315598","article-title":"Clinical and genetical features of probands and affected family members with familial exudative vitreoretinopathy in a large Chinese cohort","volume":"105","author":"Wang","year":"2021","journal-title":"Br. J. Ophthalmol."},{"issue":"3","key":"10.1016\/j.ijbiomac.2023.128570_bb0015","doi-asserted-by":"crossref","first-page":"e415","DOI":"10.1111\/aos.14586","article-title":"Early detection of ocular abnormalities in a Chinese multicentre neonatal eye screening programme-1-year result","volume":"99","author":"Fei","year":"2021","journal-title":"Acta Ophthalmol."},{"issue":"4","key":"10.1016\/j.ijbiomac.2023.128570_bb0020","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1093\/hmg\/ddr509","article-title":"Next generation sequencing identifies mutations in atonal homolog 7 (ATOH7) in families with global eye developmental defects","volume":"21","author":"Khan","year":"2012","journal-title":"Hum. Mol. Genet."},{"issue":"3","key":"10.1016\/j.ijbiomac.2023.128570_bb0025","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1086\/318790","article-title":"A new locus for autosomal dominant familial exudative vitreoretinopathy maps to chromosome 11p12-13","volume":"68","author":"Downey","year":"2001","journal-title":"Am. J. Hum. Genet."},{"issue":"1","key":"10.1016\/j.ijbiomac.2023.128570_bb0030","doi-asserted-by":"crossref","first-page":"5243","DOI":"10.1038\/s41467-019-13220-3","article-title":"Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy","volume":"10","author":"Park","year":"2019","journal-title":"Nat. Commun."},{"issue":"5","key":"10.1016\/j.ijbiomac.2023.128570_bb0035","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1086\/425080","article-title":"Autosomal recessive familial exudative vitreoretinopathy is associated with mutations in LRP5","volume":"75","author":"Jiao","year":"2004","journal-title":"Am. J. Hum. Genet."},{"issue":"4","key":"10.1016\/j.ijbiomac.2023.128570_bb0040","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1086\/383202","article-title":"Mutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q","volume":"74","author":"Toomes","year":"2004","journal-title":"Am. J. Hum. Genet."},{"issue":"2","key":"10.1016\/j.ijbiomac.2023.128570_bb0045","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.cell.2009.07.048","article-title":"TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4\/\u03b2-catenin signaling","volume":"139","author":"Junge","year":"2009","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.ijbiomac.2023.128570_bb0050","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1038\/ng1093-180","article-title":"A mutation in the Norrie disease gene (NDP) associated with X\u2013linked familial exudative vitreoretinopathy","volume":"5","author":"Chen","year":"1993","journal-title":"Nat. Genet."},{"issue":"24","key":"10.1016\/j.ijbiomac.2023.128570_bb0055","doi-asserted-by":"crossref","first-page":"9856","DOI":"10.1073\/pnas.1220864110","article-title":"ZNF408 is mutated in familial exudative vitreoretinopathy and is crucial for the development of zebrafish retinal vasculature","volume":"110","author":"Collin","year":"2013","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"12","key":"10.1016\/j.ijbiomac.2023.128570_bb0060","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1001\/jamaophthalmol.2014.2814","article-title":"Phenotypic overlap between familial exudative vitreoretinopathy and microcephaly, lymphedema, and horioretinal dysplasia caused by KIF11 mutations","volume":"132","author":"Robitaille","year":"2014","journal-title":"JAMA Ophthalmol."},{"issue":"6","key":"10.1016\/j.ijbiomac.2023.128570_bb0065","doi-asserted-by":"crossref","DOI":"10.1172\/JCI139869","article-title":"Catenin \u03b1 1 mutations cause familial exudative vitreoretinopathy by overactivating Norrin\/\u03b2-catenin signaling","volume":"131","author":"Zhu","year":"2021","journal-title":"J. Clin. Invest."},{"issue":"4","key":"10.1016\/j.ijbiomac.2023.128570_bb0070","doi-asserted-by":"crossref","first-page":"468","DOI":"10.3109\/13816810.2015.1120318","article-title":"CTNNB1 mutation associated with familial exudative vitreoretinopathy (FEVR) phenotype","volume":"37","author":"Dixon","year":"2016","journal-title":"Ophthalmic Genet."},{"issue":"1","key":"10.1016\/j.ijbiomac.2023.128570_bb0075","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/s41436-019-0571-5","article-title":"Exome sequencing revealed notch ligand JAG1 as a novel candidate gene for familial exudative vitreoretinopathy","volume":"22","author":"Zhang","year":"2020","journal-title":"Genet. Med."},{"issue":"5","key":"10.1016\/j.ijbiomac.2023.128570_bb0080","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1089\/gtmb.2021.0013","article-title":"Whole-exome sequencing identified DLG1 as a candidate gene for familial exudative vitreoretinopathy","volume":"25","author":"Zhang","year":"2021","journal-title":"Genet. Test. Mol. Biomark."},{"issue":"6","key":"10.1016\/j.ijbiomac.2023.128570_bb0085","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.jgg.2021.11.010","article-title":"Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy","volume":"49","author":"Li","year":"2022","journal-title":"J. Genet. Genom. Yi Chuan Xue Bao"},{"key":"10.1016\/j.ijbiomac.2023.128570_bb0090","doi-asserted-by":"crossref","unstructured":"Familial exudative vitreoretinopathy with TGFBR2 mutation without signs of Loeys-Dietz syndrome: Ophthalmic Genet.: Vol 42, No 5. Accessed April 26 2023. https:\/\/doi.org\/10.1080\/13816810.2021.1938137?journalCode=iopg20.","DOI":"10.1080\/13816810.2021.1938137"},{"issue":"14","key":"10.1016\/j.ijbiomac.2023.128570_bb0095","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.158428","article-title":"CTNND1 variants cause familial exudative vitreoretinopathy through the Wnt\/cadherin axis","volume":"7","author":"Yang","year":"2022","journal-title":"JCI Insight"},{"key":"10.1016\/j.ijbiomac.2023.128570_bb0100","article-title":"Defective EMC1 drives abnormal retinal angiogenesis via Wnt\/\u03b2-catenin signaling and may be associated with the pathogenesis of familial exudative vitreoretinopathy","volume":"11","author":"Li","year":"2022","journal-title":"Genes Dis."},{"issue":"2","key":"10.1016\/j.ijbiomac.2023.128570_bb0105","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.cell.2009.07.047","article-title":"Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization","volume":"139","author":"Ye","year":"2009","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.ijbiomac.2023.128570_bb0110","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/s41392-021-00762-6","article-title":"Wnt\/\u03b2-catenin signalling: function, biological mechanisms, and therapeutic opportunities","volume":"7","author":"Liu","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"issue":"1","key":"10.1016\/j.ijbiomac.2023.128570_bb0115","doi-asserted-by":"crossref","first-page":"a007898","DOI":"10.1101\/cshperspect.a007898","article-title":"The -catenin destruction complex","volume":"5","author":"Stamos","year":"2013","journal-title":"Cold Spring Harb. Perspect. Biol."},{"issue":"5","key":"10.1016\/j.ijbiomac.2023.128570_bb0120","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.molcel.2019.08.016","article-title":"Mediator condensates localize signaling factors to key cell identity genes","volume":"76","author":"Zamudio","year":"2019","journal-title":"Mol. Cell"},{"issue":"12","key":"10.1016\/j.ijbiomac.2023.128570_bb0125","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.202205069","article-title":"Dishevelled phase separation promotes Wnt signalosome assembly and destruction complex disassembly","volume":"221","author":"Kang","year":"2022","journal-title":"J. Cell Biol."},{"issue":"7","key":"10.1016\/j.ijbiomac.2023.128570_bb0130","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1007\/s11427-020-1702-x","article-title":"Liquid-liquid phase separation in biology: mechanisms, physiological functions and human diseases","volume":"63","author":"Zhang","year":"2020","journal-title":"Sci. China Life Sci."},{"issue":"2","key":"10.1016\/j.ijbiomac.2023.128570_bb0135","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1007\/s11427-022-2205-x","article-title":"Activating translation by phase separation: a novel mechanism for driving spermiogenesis","volume":"66","author":"Zhang","year":"2023","journal-title":"Sci. China Life Sci."},{"issue":"3","key":"10.1016\/j.ijbiomac.2023.128570_bb0140","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.cell.2018.12.035","article-title":"Considerations and challenges in studying liquid-liquid phase separation and biomolecular condensates","volume":"176","author":"Alberti","year":"2019","journal-title":"Cell"},{"issue":"10","key":"10.1016\/j.ijbiomac.2023.128570_bb0145","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.jgg.2021.07.012","article-title":"Phase separation in RNA biology","volume":"48","author":"Lin","year":"2021","journal-title":"J. Genet. Genomics"},{"issue":"4","key":"10.1016\/j.ijbiomac.2023.128570_bb0150","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.202012112","article-title":"Phase separation of Axin organizes the \u03b2-catenin destruction complex","volume":"220","author":"Nong","year":"2021","journal-title":"J. Cell Biol."},{"issue":"10","key":"10.1016\/j.ijbiomac.2023.128570_bb0155","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1016\/j.ophtha.2011.06.020","article-title":"Clinical presentation of familial exudative vitreoretinopathy","volume":"118","author":"Ranchod","year":"2011","journal-title":"Ophthalmology"},{"issue":"11","key":"10.1016\/j.ijbiomac.2023.128570_bb0160","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0027385","article-title":"A computational tool for quantitative analysis of vascular networks","volume":"6","author":"Zudaire","year":"2011","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.ijbiomac.2023.128570_bb0165","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1186\/s12943-021-01468-7","article-title":"Characterization of novel CTNNB1 mutation in craniopharyngioma by whole-genome sequencing","volume":"20","author":"He","year":"2021","journal-title":"Mol. Cancer"},{"issue":"7873","key":"10.1016\/j.ijbiomac.2023.128570_bb0170","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/s41586-021-03819-2","article-title":"Highly accurate protein structure prediction with AlphaFold","volume":"596","author":"Jumper","year":"2021","journal-title":"Nature"},{"issue":"D1","key":"10.1016\/j.ijbiomac.2023.128570_bb0175","doi-asserted-by":"crossref","first-page":"D439","DOI":"10.1093\/nar\/gkab1061","article-title":"AlphaFold protein structure database: massively expanding the structural coverage of protein-sequence space with high-accuracy models","volume":"50","author":"Varadi","year":"2022","journal-title":"Nucleic Acids Res."},{"issue":"12","key":"10.1016\/j.ijbiomac.2023.128570_bb0180","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1002\/prot.26171","article-title":"High-accuracy protein structure prediction in CASP14","volume":"89","author":"Pereira","year":"2021","journal-title":"Proteins Struct. Funct. Bioinform."},{"issue":"1","key":"10.1016\/j.ijbiomac.2023.128570_bb0185","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1002\/pro.3943","article-title":"UCSF ChimeraX: structure visualization for researchers, educators, and developers","volume":"30","author":"Pettersen","year":"2021","journal-title":"Protein Sci. Publ. Protein Soc."},{"issue":"1","key":"10.1016\/j.ijbiomac.2023.128570_bb0190","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1002\/pro.3235","article-title":"UCSF ChimeraX: meeting modern challenges in visualization and analysis","volume":"27","author":"Goddard","year":"2018","journal-title":"Protein Sci. Publ. Protein Soc."},{"issue":"6","key":"10.1016\/j.ijbiomac.2023.128570_bb0195","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/s41592-022-01488-1","article-title":"ColabFold: making protein folding accessible to all","volume":"19","author":"Mirdita","year":"2022","journal-title":"Nat. Methods"},{"issue":"41","key":"10.1016\/j.ijbiomac.2023.128570_bb0200","doi-asserted-by":"crossref","first-page":"28222","DOI":"10.1074\/jbc.M109.045039","article-title":"The terminal region of \u03b2-catenin promotes stability by shielding the armadillo repeats from the Axin-scaffold destruction complex","volume":"284","author":"Mo","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijbiomac.2023.128570_bb0205","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.66440","article-title":"Quantitative live-cell imaging and computational modeling shed new light on endogenous WNT\/CTNNB1 signaling dynamics","volume":"10","author":"De Man","year":"2021","journal-title":"eLife"},{"issue":"22","key":"10.1016\/j.ijbiomac.2023.128570_bb0210","doi-asserted-by":"crossref","first-page":"2753","DOI":"10.1101\/gad.1142603","article-title":"Crystal structure of a beta-catenin\/axin complex suggests a mechanism for the beta-catenin destruction complex","volume":"17","author":"Xing","year":"2003","journal-title":"Genes Dev."},{"key":"10.1016\/j.ijbiomac.2023.128570_bb0215","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/1471-2105-13-111","article-title":"MetaDisorder: a meta-server for the prediction of intrinsic disorder in proteins","volume":"13","author":"Kozlowski","year":"2012","journal-title":"BMC Bioinform."},{"issue":"W1","key":"10.1016\/j.ijbiomac.2023.128570_bb0220","doi-asserted-by":"crossref","first-page":"W402","DOI":"10.1093\/nar\/gkz297","article-title":"The PSIPRED protein analysis workbench: 20 years on","volume":"47","author":"Buchan","year":"2019","journal-title":"Nucleic Acids Res."},{"issue":"6","key":"10.1016\/j.ijbiomac.2023.128570_bb0225","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/j.molcel.2018.05.019","article-title":"Functional domains of NEAT1 architectural lncRNA induce paraspeckle assembly through phase separation","volume":"70","author":"Yamazaki","year":"2018","journal-title":"Mol. Cell"},{"issue":"1","key":"10.1016\/j.ijbiomac.2023.128570_bb0230","doi-asserted-by":"crossref","first-page":"18440","DOI":"10.1038\/s41598-019-54890-9","article-title":"\u03b2-Catenin activation down-regulates cell-cell junction-related genes and induces epithelial-to-mesenchymal transition in colorectal cancers","volume":"9","author":"Kim","year":"2019","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.ijbiomac.2023.128570_bb0235","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1152\/physrev.00035.2003","article-title":"Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis","volume":"84","author":"Bazzoni","year":"2004","journal-title":"Physiol. Rev."},{"issue":"11","key":"10.1016\/j.ijbiomac.2023.128570_bb0240","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1007\/s11427-021-1941-7","article-title":"The ER membrane protein complex subunit Emc3 controls angiogenesis via the FZD4\/WNT signaling axis","volume":"64","author":"Yang","year":"2021","journal-title":"Sci. China Life Sci."},{"key":"10.1016\/j.ijbiomac.2023.128570_bb0245","doi-asserted-by":"crossref","unstructured":"CTNNB1-related neurodevelopmental disorder in a Chinese population: a case series. doi:https:\/\/doi.org\/10.1002\/ajmg.a.62504.","DOI":"10.1002\/ajmg.a.62504"},{"issue":"12","key":"10.1016\/j.ijbiomac.2023.128570_bb0250","doi-asserted-by":"crossref","first-page":"2714","DOI":"10.1038\/emboj.2012.150","article-title":"The many faces and functions of \u03b2-catenin: \u03b2-catenin: a life by, beyond, and against the Wnt canon","volume":"31","author":"Valenta","year":"2012","journal-title":"EMBO J."},{"issue":"10","key":"10.1016\/j.ijbiomac.2023.128570_bb0255","doi-asserted-by":"crossref","DOI":"10.1002\/bies.202100138","article-title":"Liquid-liquid phase separation drives the \u03b2-catenin destruction complex formation","volume":"43","author":"Shi","year":"2021","journal-title":"BioEssays News Rev. Mol. Cell Dev. Biol."},{"issue":"4","key":"10.1016\/j.ijbiomac.2023.128570_bb0260","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1007339","article-title":"Supramolecular assembly of the beta-catenin destruction complex and the effect of Wnt signaling on its localization, molecular size, and activity in vivo","volume":"14","author":"Schaefer","year":"2018","journal-title":"PLoS Genet."}],"container-title":["International Journal of Biological Macromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813023054697?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813023054697?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T09:54:35Z","timestamp":1765792475000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0141813023054697"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":52,"alternative-id":["S0141813023054697"],"URL":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2023.128570","relation":{},"ISSN":["0141-8130"],"issn-type":[{"value":"0141-8130","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Frameshift variants in the C-terminal of CTNNB1 cause familial exudative vitreoretinopathy by AXIN1-mediated ubiquitin-proteasome degradation condensation","name":"articletitle","label":"Article Title"},{"value":"International Journal of Biological Macromolecules","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2023.128570","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"128570"}}