{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T21:23:51Z","timestamp":1793741031184,"version":"4.6.1"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T00:00:00Z","timestamp":1751241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biological Macromolecules"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.ijbiomac.2025.145642","type":"journal-article","created":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T12:20:31Z","timestamp":1751372431000},"page":"145642","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"P3","title":["A new target for curcumin in the treatment of non-alcoholic fatty liver disease: the FTO protein"],"prefix":"10.1016","volume":"319","author":[{"given":"Ye","family":"Fan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jintong","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinmeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaohong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ijbiomac.2025.145642_bb0005","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1097\/HEP.0000000000000004","article-title":"The global epidemiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH): a systematic review","volume":"77","author":"Younossi","year":"2023","journal-title":"Hepatology"},{"issue":"5","key":"10.1016\/j.ijbiomac.2025.145642_bb0010","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.bpg.2010.08.005","article-title":"Nonalcoholic fatty liver disease","volume":"24","author":"Krawczyk","year":"2010","journal-title":"Best Pract. Res. Clin. Gastroenterol."},{"issue":"42","key":"10.1016\/j.ijbiomac.2025.145642_bb0015","doi-asserted-by":"crossref","first-page":"15532","DOI":"10.3748\/wjg.v20.i42.15532","article-title":"Liver transplantation and non-alcoholic fatty liver disease","volume":"20","author":"Zezos","year":"2014","journal-title":"World J. Gastroenterol."},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.145642_bb0020","first-page":"42","article-title":"Non-alcoholic fatty liver disease, an overview","volume":"18","author":"Nd","year":"2019","journal-title":"Integr. Med. (Encinitas)"},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.145642_bb0025","first-page":"115","article-title":"Research advances in diagnosis of non-alcoholic fatty liver disease","volume":"25","author":"Wang","year":"2017","journal-title":"Zhonghua Ganzangbing Zazhi"},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.145642_bb0030","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1002\/hep.27678","article-title":"Challenges and opportunities in drug and biomarker development for nonalcoholic steatohepatitis: findings and recommendations from an American Association for the Study of Liver Diseases-U.S. Food and Drug Administration joint workshop","volume":"61","author":"Sanyal","year":"2015","journal-title":"Hepatology"},{"issue":"5","key":"10.1016\/j.ijbiomac.2025.145642_bb0035","article-title":"The role of Thiazolidinediones in the amelioration of nonalcoholic fatty liver disease: a systematic review","volume":"14","author":"Ndakotsu","year":"2022","journal-title":"Cureus"},{"issue":"25","key":"10.1016\/j.ijbiomac.2025.145642_bb0040","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.3748\/wjg.v24.i25.2661","article-title":"Apoptosis and non-alcoholic fatty liver diseases","volume":"24","author":"Kanda","year":"2018","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.ijbiomac.2025.145642_bb0045","doi-asserted-by":"crossref","unstructured":"P. Halagali, A. Inamdar, J. Singh, A. Anand, P. Sadhu, R. Pathak, H. Sharma, D. Biswas, Phytochemicals, Herbal Extracts, and Dietary Supplements for Metabolic Disease Management, Endocr., Metab. Immune Disord.: Drug Targets. (2024).","DOI":"10.2174\/0118715303287911240409055710"},{"key":"10.1016\/j.ijbiomac.2025.145642_bb0050","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.smallrumres.2019.04.011","article-title":"The effect of adding fennel (Foeniculum vulgare) seed powder to the diet of fattening lambs on performance, carcass characteristics and liver enzymes","volume":"175","author":"Hajalizadeh","year":"2019","journal-title":"Small Rumin. Res."},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.145642_bb0055","first-page":"21","article-title":"Effect of fennel (Foeniculum Vulgare) seed powder consumption on insulin-like growth factor 1 gene expression in the liver tissue of growing lambs","volume":"21","author":"Shahsavari","year":"2022","journal-title":"Gene Expr."},{"key":"10.1016\/j.ijbiomac.2025.145642_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2021.173976","article-title":"Research progress in use of traditional Chinese medicine monomer for treatment of non-alcoholic fatty liver disease","volume":"898","author":"Zhou","year":"2021","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.145642_bb0065","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/hep.32221","article-title":"Breviscapine alleviates NASH by inhibiting TGF-\u03b2-activated kinase 1-dependent signaling","volume":"76","author":"Lan","year":"2022","journal-title":"Hepatology"},{"key":"10.1016\/j.ijbiomac.2025.145642_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216332","article-title":"Curcumin in cancer therapy: exploring molecular mechanisms and overcoming clinical challenges","volume":"570","author":"Wang","year":"2023","journal-title":"Cancer Lett."},{"issue":"12","key":"10.1016\/j.ijbiomac.2025.145642_bb0075","doi-asserted-by":"crossref","first-page":"4440","DOI":"10.3390\/nu13124440","article-title":"Curcumin in metabolic health and disease","volume":"13","author":"Jabczyk","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.ijbiomac.2025.145642_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.biotechadv.2019.01.010","article-title":"Curcumin, the golden spice in treating cardiovascular diseases","volume":"38","author":"Li","year":"2020","journal-title":"Biotechnol. Adv."},{"issue":"8","key":"10.1016\/j.ijbiomac.2025.145642_bb0085","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1517\/13543784.2012.693479","article-title":"Curcumin and neurodegenerative diseases: a perspective","volume":"21","author":"Darvesh","year":"2012","journal-title":"Expert Opin. Investig. Drugs"},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.145642_bb0090","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/ptr.8051","article-title":"Effects of curcumin\/turmeric supplementation on the liver enzymes, lipid profiles, glycemic index, and anthropometric indices in non-alcoholic fatty liver patients: an umbrella meta-analysis","volume":"38","author":"Molani-Gol","year":"2024","journal-title":"Phytother. Res."},{"issue":"11","key":"10.1016\/j.ijbiomac.2025.145642_bb0095","doi-asserted-by":"crossref","first-page":"2702","DOI":"10.3390\/nu11112702","article-title":"Curcumin ameliorates nonalcoholic fatty liver disease through inhibition of O-GlcNAcylation","volume":"11","author":"Lee","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.ijbiomac.2025.145642_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.155241","article-title":"Effects of curcumin on non-alcoholic fatty liver disease: a scientific metrogy study","volume":"123","author":"Li","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.ijbiomac.2025.145642_bb0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnutbio.2022.109103","article-title":"Hepatoprotective effect of curcumin against bisphenol A-induced hepatic steatosis via modulating gut microbiota dysbiosis and related gut-liver axis activation in CD-1 mice","volume":"109","author":"Hong","year":"2022","journal-title":"J. Nutr. Biochem."},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.145642_bb0110","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1039\/D1FO03752H","article-title":"Curcumin alleviates hepatic steatosis by improving mitochondrial function in postnatal overfed rats and fatty L02 cells through the SIRT3 pathway","volume":"13","author":"Du","year":"2022","journal-title":"Food Funct."},{"issue":"1\u20132","key":"10.1016\/j.ijbiomac.2025.145642_bb0115","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.mce.2010.05.019","article-title":"Peroxisome proliferator activated receptor alpha (PPARalpha) and PPAR gamma coactivator (PGC-1alpha) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements","volume":"325","author":"Song","year":"2010","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.ijbiomac.2025.145642_bb0120","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.63538","article-title":"Curcumin promotes AApoAII amyloidosis and peroxisome proliferation in mice by activating the PPAR\u03b1 signaling pathway","volume":"10","author":"Dai","year":"2021","journal-title":"Elife"},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.145642_bb0125","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.ymthe.2024.12.003","article-title":"Exploring the methyl-verse: dynamic interplay of epigenome and m6A epitranscriptome","volume":"33","author":"Pilala","year":"2025","journal-title":"Mol. Ther."},{"issue":"5","key":"10.1016\/j.ijbiomac.2025.145642_bb0130","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1038\/s41437-020-0301-4","article-title":"Integration of single nucleotide variants and whole-genome DNA methylation profiles for classification of rheumatoid arthritis cases from controls","volume":"124","author":"Amiri Roudbar","year":"2020","journal-title":"Heredity (Edinb)"},{"issue":"11","key":"10.1016\/j.ijbiomac.2025.145642_bb0135","first-page":"2016","article-title":"Genome-wide analysis of CpG islands in some livestock genomes and their relationship with genomic features","volume":"61","author":"Barazandeh","year":"2016","journal-title":"Czeh J. Anim. Sci."},{"issue":"3","key":"10.1016\/j.ijbiomac.2025.145642_bb0140","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.bbagrm.2018.12.001","article-title":"The role of RNA adenosine demethylases in the control of gene expression","volume":"1862","author":"Rajecka","year":"2019","journal-title":"Biochim. Biophys. Acta, Gene Regul. Mech."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.145642_bb0145","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.gendis.2021.01.005","article-title":"Critical roles of FTO-mediated mRNA m6A demethylation in regulating adipogenesis and lipid metabolism: implications in lipid metabolic disorders","volume":"9","author":"Yang","year":"2022","journal-title":"Genes Dis."},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.145642_bb0150","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1007\/s10620-012-2516-6","article-title":"Fat mass and obesity-associated gene enhances oxidative stress and lipogenesis in nonalcoholic fatty liver disease","volume":"58","author":"Guo","year":"2013","journal-title":"Dig. Dis. Sci."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.145642_bb0155","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s12944-022-01640-y","article-title":"Fat mass and obesity-associated protein promotes liver steatosis by targeting PPAR\u03b1","volume":"21","author":"Wei","year":"2022","journal-title":"Lipids Health Dis."},{"issue":"6","key":"10.1016\/j.ijbiomac.2025.145642_bb0160","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.jhep.2019.08.005","article-title":"Microbiota-driven gut vascular barrier disruption is a prerequisite for non-alcoholic steatohepatitis development","volume":"71","author":"Mouries","year":"2019","journal-title":"J. Hepatol."},{"issue":"11","key":"10.1016\/j.ijbiomac.2025.145642_bb0165","doi-asserted-by":"crossref","first-page":"6280","DOI":"10.3390\/ijms25116280","article-title":"Cilostazol attenuates hepatic steatosis and intestinal disorders in nonalcoholic fatty liver disease","volume":"25","author":"Min","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ijbiomac.2025.145642_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.116343","article-title":"Curcumin alleviates zearalenone-induced liver injury in mice by scavenging reactive oxygen species and inhibiting mitochondrial apoptosis pathway","volume":"277","author":"Yang","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"8","key":"10.1016\/j.ijbiomac.2025.145642_bb0175","first-page":"1015","article-title":"Curcumin and saroglitazar attenuate diet-induced nonalcoholic steatohepatitis by activating the Nrf2 pathway and suppressing ERK1\/2 signaling, Iran","volume":"27","author":"Afarin","year":"2024","journal-title":"J. Basic Med. Sci."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.145642_bb0180","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.atherosclerosis.2013.10.016","article-title":"Curcumin modulation of high fat diet-induced atherosclerosis and steatohepatosis in LDL receptor deficient mice","volume":"232","author":"Hasan","year":"2014","journal-title":"Atherosclerosis"},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.145642_bb0185","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3892\/mmr.2023.13141","article-title":"Overexpression of salusin-\u03b2 downregulates adipoR1 expression to prevent fatty acid oxidation in HepG2 cells","volume":"29","author":"Xu","year":"2024","journal-title":"Mol. Med. Rep."},{"issue":"D1","key":"10.1016\/j.ijbiomac.2025.145642_bb0190","doi-asserted-by":"crossref","first-page":"D833","DOI":"10.1093\/nar\/gkw943","article-title":"DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants","volume":"45","author":"Pi\u00f1ero","year":"2017","journal-title":"Nucleic Acids Res."},{"issue":"W1","key":"10.1016\/j.ijbiomac.2025.145642_bb0195","doi-asserted-by":"crossref","first-page":"W216","DOI":"10.1093\/nar\/gkac194","article-title":"DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)","volume":"50","author":"Sherman","year":"2022","journal-title":"Nucleic Acids Res."},{"issue":"11","key":"10.1016\/j.ijbiomac.2025.145642_bb0200","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0294236","article-title":"SRplot: a free online platform for data visualization and graphing","volume":"18","author":"Tang","year":"2023","journal-title":"PLoS One"},{"issue":"D1","key":"10.1016\/j.ijbiomac.2025.145642_bb0205","doi-asserted-by":"crossref","first-page":"D437","DOI":"10.1093\/nar\/gkaa1038","article-title":"RCSB protein data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences","volume":"49","author":"Burley","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ijbiomac.2025.145642_bb0210","first-page":"13","article-title":"TCMSP: a database of systems pharmacology for drug discovery from herbal medicines","volume":"6","author":"Ru","year":"2014","journal-title":"J. Chem."},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.145642_bb0215","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/jcc.21334","article-title":"AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading","volume":"31","author":"Trott","year":"2010","journal-title":"J. Comput. Chem."},{"issue":"W1","key":"10.1016\/j.ijbiomac.2025.145642_bb0220","doi-asserted-by":"crossref","first-page":"W530","DOI":"10.1093\/nar\/gkab294","article-title":"PLIP 2021: expanding the scope of the protein-ligand interaction profiler to DNA and RNA","volume":"49","author":"Adasme","year":"2021","journal-title":"Nucleic Acids Res."},{"issue":"10","key":"10.1016\/j.ijbiomac.2025.145642_bb0225","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkw104","article-title":"SRAMP: prediction of mammalian N6-methyladenosine (m6A) sites based on sequence-derived features","volume":"44","author":"Zhou","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ijbiomac.2025.145642_bb0230","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s12986-019-0331-1","article-title":"Nano-curcumin improves glucose indices, lipids, inflammation, and Nesfatin in overweight and obese patients with non-alcoholic fatty liver disease (NAFLD): a double-blind randomized placebo-controlled clinical trial","volume":"16","author":"Jazayeri-Tehrani","year":"2019","journal-title":"Nutr. Metab. (Lond.)"},{"key":"10.1016\/j.ijbiomac.2025.145642_bb0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.ctim.2022.102843","article-title":"Curcumin as adjuvant treatment in patients with non-alcoholic fatty liver (NAFLD) disease: a systematic review and meta-analysis","volume":"68","author":"Ngu","year":"2022","journal-title":"Complement. Ther. Med."},{"issue":"12","key":"10.1016\/j.ijbiomac.2025.145642_bb0240","doi-asserted-by":"crossref","first-page":"4440","DOI":"10.3390\/nu13124440","article-title":"Curcumin in metabolic health and disease","volume":"13","author":"Jabczyk","year":"2021","journal-title":"Nutrients"},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.145642_bb0245","doi-asserted-by":"crossref","first-page":"3323","DOI":"10.3390\/ijms24043323","article-title":"Therapeutic effect of curcumin on metabolic diseases: evidence from clinical studies","volume":"24","author":"Zeng","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ijbiomac.2025.145642_bb0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.155234","article-title":"Curcumin and analogues in mitigating liver injury and disease consequences: from molecular mechanisms to clinical perspectives","volume":"123","author":"Jiang","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.ijbiomac.2025.145642_bb0255","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.biopha.2018.05.135","article-title":"Curcumin regulates endogenous and exogenous metabolism via Nrf2-FXR-LXR pathway in NAFLD mice","volume":"105","author":"Yan","year":"2018","journal-title":"Biomed. Pharmacother."},{"issue":"3","key":"10.1016\/j.ijbiomac.2025.145642_bb0260","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.jhep.2014.10.039","article-title":"Molecular mechanism of PPAR\u03b1 action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease","volume":"62","author":"Pawlak","year":"2015","journal-title":"J. Hepatol."},{"issue":"7","key":"10.1016\/j.ijbiomac.2025.145642_bb0265","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/1751-2980.12610","article-title":"Fatty liver mediated by peroxisome proliferator-activated receptor-\u03b1 DNA methylation can be reversed by a methylation inhibitor and curcumin","volume":"19","author":"Li","year":"2018","journal-title":"J. Dig. Dis."},{"issue":"11","key":"10.1016\/j.ijbiomac.2025.145642_bb0270","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1038\/nrm4074","article-title":"Transcriptional regulation of hepatic lipogenesis","volume":"16","author":"Wang","year":"2015","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"6","key":"10.1016\/j.ijbiomac.2025.145642_bb0275","doi-asserted-by":"crossref","first-page":"2342","DOI":"10.1016\/j.ymthe.2022.02.021","article-title":"Dysregulated m6A modification promotes lipogenesis and development of non-alcoholic fatty liver disease and hepatocellular carcinoma","volume":"30","author":"Yang","year":"2022","journal-title":"Mol. Ther."},{"issue":"9","key":"10.1016\/j.ijbiomac.2025.145642_bb0280","doi-asserted-by":"crossref","DOI":"10.1093\/jmcb\/mjac061","article-title":"Aberrant elevation of FTO levels promotes liver steatosis by decreasing the m6A methylation and increasing the stability of SREBF1 and ChREBP mRNAs","volume":"14","author":"Tang","year":"2023","journal-title":"J. Mol. Cell Biol."},{"issue":"3","key":"10.1016\/j.ijbiomac.2025.145642_bb0285","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.jhep.2020.04.009","article-title":"Epitranscriptomics in liver disease: basic concepts and therapeutic potential","volume":"73","author":"Zhao","year":"2020","journal-title":"J. Hepatol."}],"container-title":["International Journal of Biological Macromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813025061975?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813025061975?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T02:12:23Z","timestamp":1770775943000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0141813025061975"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":57,"alternative-id":["S0141813025061975"],"URL":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2025.145642","relation":{},"ISSN":["0141-8130"],"issn-type":[{"value":"0141-8130","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A new target for curcumin in the treatment of non-alcoholic fatty liver disease: the FTO protein","name":"articletitle","label":"Article Title"},{"value":"International Journal of Biological Macromolecules","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2025.145642","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"145642"}}