{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T15:21:24Z","timestamp":1792596084869,"version":"4.5.0"},"reference-count":163,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biological Macromolecules"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.ijbiomac.2025.147264","type":"journal-article","created":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T15:03:39Z","timestamp":1756566219000},"page":"147264","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"P1","title":["Applications of chitosan-based hydrogels in diabetic wound healing: A review"],"prefix":"10.1016","volume":"324","author":[{"given":"Weiwei","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ijbiomac.2025.147264_bb0005","doi-asserted-by":"crossref","DOI":"10.1002\/hsr2.1170","article-title":"Prevalence of diabetes and its correlates among Iranian adults: results of the first phase of Shahedieh cohort study","volume":"6","author":"Dehghani","year":"2023","journal-title":"Health Sci. Rep."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2024.122984","article-title":"Gene-engineered polypeptide hydrogels with on-demand oxygenation and ECM-cell interaction mimicry for diabetic wound healing","volume":"316","author":"Xie","year":"2025","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0015","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s40200-024-01510-7","article-title":"Injectable hydrogels for treating skin injuries in diabetic animal models: a systematic review","volume":"24","author":"Amaral","year":"2024","journal-title":"J. Diabetes Metab. Disord."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0020","first-page":"65","article-title":"The role of the immune microenvironment in bone, cartilage, and soft tissue regeneration: from mechanism to therapeutic opportunity","volume":"9","author":"Xiong","year":"2022","journal-title":"Mil. Med. Res."},{"issue":"25","key":"10.1016\/j.ijbiomac.2025.147264_bb0025","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202300779","article-title":"Reactive oxygen species-scavenging nanosystems in the treatment of diabetic wounds","volume":"12","author":"Xiong","year":"2023","journal-title":"Adv. Healthc. Mater."},{"issue":"8","key":"10.1016\/j.ijbiomac.2025.147264_bb0030","article-title":"Multifunctional PtCuTe nanosheets with strong ROS scavenging and ROS-independent antibacterial properties promote diabetic wound healing","volume":"36","author":"Guo","year":"2024","journal-title":"Adv. Mater. (Deerfield Beach, Fla)"},{"issue":"11","key":"10.1016\/j.ijbiomac.2025.147264_bb0035","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.1094","article-title":"Anti-inflammatory hydrogel dressings and skin wound healing","volume":"12","author":"Huang","year":"2022","journal-title":"Clin. Transl. Med."},{"issue":"21","key":"10.1016\/j.ijbiomac.2025.147264_bb0040","doi-asserted-by":"crossref","first-page":"22015","DOI":"10.1021\/acsnano.3c08625","article-title":"Injectable Antiswelling and high-strength bioactive hydrogels with a wet adhesion and rapid gelling process to promote Sutureless wound closure and scar-free repair of infectious wounds","volume":"17","author":"Zhao","year":"2023","journal-title":"ACS Nano"},{"issue":"6","key":"10.1016\/j.ijbiomac.2025.147264_bb0045","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1089\/wound.2024.0024","article-title":"Natural polymer\u2013based hydrogel dressings for wound healing","volume":"14","author":"Cai","year":"2024","journal-title":"Adv. Wound Care."},{"issue":"8","key":"10.1016\/j.ijbiomac.2025.147264_bb0050","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.progpolymsci.2011.02.001","article-title":"Chitosan\u2014a versatile semi-synthetic polymer in biomedical applications","volume":"36","author":"Dash","year":"2011","journal-title":"Prog. Polym. Sci."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0055","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.addr.2009.07.019","article-title":"Chitosan-based hydrogels for controlled, localized drug delivery","volume":"62","author":"Bhattarai","year":"2010","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"13","key":"10.1016\/j.ijbiomac.2025.147264_bb0060","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202102749","article-title":"Supramolecular Thermo-contracting adhesive hydrogel with self-removability simultaneously enhancing noninvasive wound closure and MRSA-infected wound healing","volume":"11","author":"Yu","year":"2022","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0065","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1016\/j.carbpol.2013.10.056","article-title":"Solution blowing of chitosan\/PVA hydrogel nanofiber mats","volume":"101","author":"Liu","year":"2014","journal-title":"Carbohydr. Polym."},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.147264_bb0070","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1021\/bm010083r","article-title":"Preparation of chitosan gel beads by ionotropic molybdate gelation","volume":"2","author":"Dambies","year":"2001","journal-title":"Biomacromolecules"},{"issue":"3","key":"10.1016\/j.ijbiomac.2025.147264_bb0075","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1177\/0022034509359125","article-title":"Factors affecting wound healing","volume":"89","author":"Guo","year":"2010","journal-title":"J. Dent. Res."},{"issue":"6342","key":"10.1016\/j.ijbiomac.2025.147264_bb0080","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1126\/science.aam7928","article-title":"Inflammation and metabolism in tissue repair and regeneration","volume":"356","author":"Eming","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0085","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.addr.2018.12.014","article-title":"Advanced drug delivery systems and artificial skin grafts for skin wound healing","volume":"146","author":"Kim","year":"2019","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.147264_bb0090","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.suc.2020.05.007","article-title":"Bacteria and antibiotics in wound healing","volume":"100","author":"Caldwell","year":"2020","journal-title":"Surg. Clin. North Am."},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.147264_bb0095","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1111\/bjd.13954","article-title":"Cellular and molecular mechanisms of repair in acute and chronic wound healing","volume":"173","author":"Martin","year":"2015","journal-title":"Br. J. Dermatol."},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.147264_bb0100","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1385\/MB:28:2:147","article-title":"Wound-healing studies in transgenic and knockout mice","volume":"28","author":"Grose","year":"2004","journal-title":"Mol. Biotechnol."},{"issue":"9","key":"10.1016\/j.ijbiomac.2025.147264_bb0105","doi-asserted-by":"crossref","first-page":"2891","DOI":"10.1016\/j.ymthe.2022.07.016","article-title":"Macrophages as a therapeutic target to promote diabetic wound healing","volume":"30","author":"Sharifiaghdam","year":"2022","journal-title":"Mol. Ther."},{"issue":"11","key":"10.1016\/j.ijbiomac.2025.147264_bb0110","doi-asserted-by":"crossref","DOI":"10.3390\/biom12111659","article-title":"Macrophages in skin wounds: functions and therapeutic potential","volume":"12","author":"Sim","year":"2022","journal-title":"Biomolecules"},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0115","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1046\/j.1087-0024.2000.00014.x","article-title":"Angiogenesis in wound healing","volume":"5","author":"Tonnesen","year":"2000","journal-title":"J. Invest. Derm. Symp. Proc."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0120","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.addr.2018.06.019","article-title":"Re-epithelialization of adult skin wounds: cellular mechanisms and therapeutic strategies","volume":"146","author":"Rousselle","year":"2019","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"11","key":"10.1016\/j.ijbiomac.2025.147264_bb0125","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22115474","article-title":"Mechanical and immunological regulation in wound healing and skin reconstruction","volume":"22","author":"Kimura","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"8","key":"10.1016\/j.ijbiomac.2025.147264_bb0130","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.stem.2022.07.006","article-title":"Wound healing, fibroblast heterogeneity, and fibrosis","volume":"29","author":"Talbott","year":"2022","journal-title":"Cell Stem Cell"},{"issue":"5","key":"10.1016\/j.ijbiomac.2025.147264_bb0135","doi-asserted-by":"crossref","first-page":"Xxi","DOI":"10.1046\/j.1523-1747.2003.12575.x","article-title":"Fibrin is a many splendored thing","volume":"121","author":"Clark","year":"2003","journal-title":"J. Invest. Dermatol."},{"issue":"7","key":"10.1016\/j.ijbiomac.2025.147264_bb0140","first-page":"643","article-title":"Skin wound healing modulation by macrophages","volume":"3","author":"Rodero","year":"2010","journal-title":"Int. J. Clin. Exp. Pathol."},{"issue":"21","key":"10.1016\/j.ijbiomac.2025.147264_bb0145","doi-asserted-by":"crossref","first-page":"4111","DOI":"10.1007\/s00018-015-1995-y","article-title":"Macrophage polarization in pathology","volume":"72","author":"Sica","year":"2015","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2022.114298","article-title":"Reprograming the immune niche for skin tissue regeneration - from cellular mechanisms to biomaterials applications","volume":"185","author":"Mu","year":"2022","journal-title":"Adv. Drug Deliver. Rev."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2024.122984","article-title":"Gene-engineered polypeptide hydrogels with on-demand oxygenation and ECM-cell interaction mimicry for diabetic wound healing","volume":"316","author":"Xie","year":"2025","journal-title":"Biomaterials"},{"issue":"3 Pt A","key":"10.1016\/j.ijbiomac.2025.147264_bb0160","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.jid.2021.08.428","article-title":"IL-10 dysregulation underlies chemokine insufficiency, delayed macrophage response, and impaired healing in diabetic wounds","volume":"142","author":"Roy","year":"2022","journal-title":"J. Invest. Dermatol."},{"issue":"5","key":"10.1016\/j.ijbiomac.2025.147264_bb0165","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1161\/ATVBAHA.118.310703","article-title":"Ly6C(hi) blood monocyte\/macrophage drive chronic inflammation and impair wound healing in diabetes mellitus","volume":"38","author":"Kimball","year":"2018","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"3","key":"10.1016\/j.ijbiomac.2025.147264_bb0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0091574","article-title":"Pro-inflammatory chemokine CCL2 (MCP-1) promotes healing in diabetic wounds by restoring the macrophage response","volume":"9","author":"Wood","year":"2014","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.147264_bb0175","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.cyto.2011.06.016","article-title":"Dysregulation of monocyte\/macrophage phenotype in wounds of diabetic mice","volume":"56","author":"Mirza","year":"2011","journal-title":"Cytokine"},{"issue":"12","key":"10.1016\/j.ijbiomac.2025.147264_bb0180","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0028469","article-title":"The metabolic reprogramming evoked by nitrosative stress triggers the anaerobic utilization of citrate in Pseudomonas fluorescens","volume":"6","author":"Auger","year":"2011","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.ijbiomac.2025.147264_bb0185","doi-asserted-by":"crossref","first-page":"415","DOI":"10.3390\/antiox10030415","article-title":"Generation of reactive oxygen species by mitochondria","volume":"10","author":"Hernansanz-Agust\u00edn","year":"2021","journal-title":"Antioxidants-Basel"},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0190","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.aquatox.2010.10.006","article-title":"Environmentally induced oxidative stress in aquatic animals","volume":"101","author":"Lushchak","year":"2011","journal-title":"Aquat. Toxicol."},{"issue":"R1","key":"10.1016\/j.ijbiomac.2025.147264_bb0195","doi-asserted-by":"crossref","first-page":"R12","DOI":"10.1093\/hmg\/ddae048","article-title":"Molecular and cellular consequences of mitochondrial DNA double-stranded breaks","volume":"33","author":"Yu","year":"2024","journal-title":"Hum. Mol. Genet."},{"issue":"12","key":"10.1016\/j.ijbiomac.2025.147264_bb0200","doi-asserted-by":"crossref","DOI":"10.3390\/genes8120398","article-title":"The mitochondrial basis of aging and age-related disorders","volume":"8","author":"Srivastava","year":"2017","journal-title":"Genes (Basel)"},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.147264_bb0205","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.gene.2013.03.062","article-title":"Receptor for advanced glycation end-product (RAGE) gene polymorphism 2245G\/a is associated with pro-inflammatory, oxidative-glycation markers and sRAGE in diabetic retinopathy","volume":"521","author":"Ng","year":"2013","journal-title":"Gene"},{"issue":"11","key":"10.1016\/j.ijbiomac.2025.147264_bb0210","doi-asserted-by":"crossref","first-page":"2878","DOI":"10.1007\/s00125-011-2271-9","article-title":"Global IRS-1 phosphorylation analysis in insulin resistance","volume":"54","author":"Langlais","year":"2011","journal-title":"Diabetologia"},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.147264_bb0215","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0014-5793(99)01255-7","article-title":"NO induces a cGMP-independent release of cytochrome from mitochondria which precedes caspase 3 activation in insulin producing RINm5F cells","volume":"459","author":"Tejedo","year":"1999","journal-title":"FEBS Lett."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0220","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s00105-024-05441-5","article-title":"Bakterielle kutane Infektionen bei Diabetes mellitus und Behandlung","volume":"76","author":"Makrantonaki","year":"2024","journal-title":"Die Dermatologie"},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.147264_bb0225","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0060057","article-title":"Skin and soft tissue infections and associated complications among commercially insured patients aged 0-64 years with and without diabetes in the US","volume":"8","author":"Suaya","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0230","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.actbio.2020.02.022","article-title":"Antibacterial biohybrid nanofibers for wound dressings","volume":"107","author":"Homaeigohar","year":"2020","journal-title":"Acta Biomater."},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.147264_bb0235","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.jaad.2015.08.068","article-title":"Wound healing and treating wounds: differential diagnosis and evaluation of chronic wounds","volume":"74","author":"Morton","year":"2016","journal-title":"J. Am. Acad. Dermatol."},{"issue":"Suppl. 3","key":"10.1016\/j.ijbiomac.2025.147264_bb0240","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/jdv.18854","article-title":"Wound healing and microbiome, an unexpected relationship","volume":"37","author":"Canchy","year":"2023","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2022.119161","article-title":"Recent advances in polysaccharide-based self-healing hydrogels for biomedical applications","volume":"283","author":"Yang","year":"2022","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.cis.2024.103267","article-title":"Chitosan-based self-healing hydrogel dressing for wound healing","volume":"332","author":"Zhang","year":"2024","journal-title":"Adv. Colloid Interface Sci."},{"issue":"16","key":"10.1016\/j.ijbiomac.2025.147264_bb0255","doi-asserted-by":"crossref","DOI":"10.3390\/molecules24163005","article-title":"Hydrogels based on Schiff Base linkages for biomedical applications","volume":"24","author":"Xu","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0260","article-title":"A review of self-healing hydrogels for bone repair and regeneration: materials, mechanisms, and applications","volume":"287","author":"Li","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.138784","article-title":"Injectable and self-healing carboxymethyl chitosan\/carboxymethyl cellulose\/marine snail peptide hydrogel for infected wound healing","volume":"288","author":"Ren","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0270","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.actbio.2024.12.020","article-title":"Corrole-based photothermal nanocomposite hydrogel with nitric oxide release for diabetic wound healing","volume":"192","author":"Yang","year":"2024","journal-title":"Acta Biomater."},{"issue":"26","key":"10.1016\/j.ijbiomac.2025.147264_bb0275","doi-asserted-by":"crossref","first-page":"14630","DOI":"10.1039\/D1TA02308J","article-title":"Recent progress in self-healing polymers and hydrogels based on reversible dynamic B-O bonds: boronic\/boronate esters, borax, and benzoxaborole","volume":"9","author":"Cho","year":"2021","journal-title":"J. Mater. Chem. A"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0280","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.jcis.2024.12.138","article-title":"An antibacterial and antioxidant rosmarinic acid hydrogel normalizes macrophage polarization to expedite diabetic wound healing","volume":"683","author":"Xiong","year":"2025","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.138509","article-title":"Catechol-grafted chitosan-based antioxidant hydrogel with rapid self-healing property for wound healing","volume":"288","author":"Zhong","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"37","key":"10.1016\/j.ijbiomac.2025.147264_bb0290","doi-asserted-by":"crossref","first-page":"41726","DOI":"10.1021\/acsami.2c10490","article-title":"Antibacterial conductive UV-blocking adhesion hydrogel dressing with mild on-demand removability accelerated drug-resistant Bacteria-infected wound healing","volume":"14","author":"Yang","year":"2022","journal-title":"Acs Appl. Mater. Interfaces"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0295","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2020.117286","article-title":"Hyaluronic acid thiol modified injectable hydrogel: synthesis, characterization, drug release, cellular drug uptake and anticancer activity","volume":"254","author":"Xu","year":"2021","journal-title":"Carbohyd. Polym."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0300","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2022.119334","article-title":"Thiolated hyaluronic acid\/silk fibroin dual-network hydrogel incorporated with bioglass nanoparticles for wound healing","volume":"288","author":"Yu","year":"2022","journal-title":"Carbohyd. Polym."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0305","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2025.123374","article-title":"Injectable self-crosslinking hyaluronic acid\/silk fibroin blend hydrogel based on disulfide bond","volume":"356","author":"Feng","year":"2025","journal-title":"Carbohyd. Polym."},{"issue":"6","key":"10.1016\/j.ijbiomac.2025.147264_bb0310","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1039\/C3CS60326A","article-title":"Disulfide exchange: exposing supramolecular reactivity through dynamic covalent chemistry","volume":"43","author":"Black","year":"2014","journal-title":"Chem. Soc. Rev."},{"issue":"19","key":"10.1016\/j.ijbiomac.2025.147264_bb0315","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202400242","article-title":"One stone three birds: silver sulfadiazine modulates the stability and dynamics of hydrogels for infected wound healing","volume":"13","author":"Huang","year":"2024","journal-title":"Adv. Healthc. Mater."},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.147264_bb0320","doi-asserted-by":"crossref","first-page":"2597","DOI":"10.1021\/cr800346f","article-title":"What is the Covalency of hydrogen bonding?","volume":"111","author":"Grabowski","year":"2011","journal-title":"Chem. Rev."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0325","doi-asserted-by":"crossref","DOI":"10.1016\/j.cis.2024.103267","article-title":"Chitosan-based self-healing hydrogel dressing for wound healing","volume":"332","author":"Zhang","year":"2024","journal-title":"Adv. Colloid Interface"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0330","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.140219","article-title":"Lutein-loaded multifunctional hydrogel dressing based on carboxymethyl chitosan for chronic wound healing","volume":"300","author":"Zhang","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"30","key":"10.1016\/j.ijbiomac.2025.147264_bb0335","doi-asserted-by":"crossref","first-page":"34455","DOI":"10.1021\/acsami.2c08870","article-title":"Injectable self-healing adhesive chitosan hydrogel with Antioxidative, antibacterial, and hemostatic activities for rapid hemostasis and skin wound healing","volume":"14","author":"Guo","year":"2022","journal-title":"Acs Appl. Mater. Interfaces"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0340","article-title":"A multifunctional hydrogel system with synergistic effects against infections and inflammation in perioperative cataract surgery","volume":"33","author":"Zheng","year":"2025","journal-title":"Mater. Today Bio"},{"issue":"27","key":"10.1016\/j.ijbiomac.2025.147264_bb0345","doi-asserted-by":"crossref","DOI":"10.1002\/adma.201903762","article-title":"Self-healing polymers based on coordination bonds","volume":"32","author":"Li","year":"2020","journal-title":"Adv. Mater."},{"issue":"34","key":"10.1016\/j.ijbiomac.2025.147264_bb0350","doi-asserted-by":"crossref","first-page":"16803","DOI":"10.1021\/jp203799m","article-title":"Coordination bonding-based mesoporous silica for pH-responsive anticancer drug doxorubicin delivery","volume":"115","author":"Zheng","year":"2011","journal-title":"J. Phys. Chem. C"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0355","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.carbpol.2019.01.047","article-title":"Layer-by-layer immobilization of amphoteric carboxymethyl chitosan onto biocompatible silk fibroin nanofibrous mats","volume":"210","author":"Tu","year":"2019","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0360","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2020.124888","article-title":"Conductive adhesive self-healing nanocomposite hydrogel wound dressing for photothermal therapy of infected full-thickness skin wounds","volume":"394","author":"He","year":"2020","journal-title":"Chem. Eng. J."},{"issue":"20","key":"10.1016\/j.ijbiomac.2025.147264_bb0365","doi-asserted-by":"crossref","first-page":"24095","DOI":"10.1021\/acsami.1c02089","article-title":"Ultrafast fabrication of self-healing and injectable Carboxymethyl chitosan hydrogel dressing for wound healing","volume":"13","author":"Cao","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"22","key":"10.1016\/j.ijbiomac.2025.147264_bb0370","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232213939","article-title":"Treatment of periodontal inflammation in diabetic rats with IL-1ra thermosensitive hydrogel","volume":"23","author":"Liu","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0375","article-title":"Multifunctional dendrimer@nanoceria engineered GelMA hydrogel accelerates bone regeneration through orchestrated cellular responses","volume":"20","author":"Kurian","year":"2023","journal-title":"Mater. Today Bio"},{"issue":"6","key":"10.1016\/j.ijbiomac.2025.147264_bb0380","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1021\/acs.chemmater.2c03550","article-title":"Modular design and bonding mechanism of internal boron-nitrogen coordinated Boronic Ester hydrogels with alkaline pH responsiveness and tunable gelation pH","volume":"35","author":"Kang","year":"2023","journal-title":"Chem. Mater."},{"issue":"22","key":"10.1016\/j.ijbiomac.2025.147264_bb0385","doi-asserted-by":"crossref","first-page":"8147","DOI":"10.1021\/acs.iecr.1c01277","article-title":"Injectable temperature\/glucose dual-responsive hydrogels for controlled release of insulin","volume":"60","author":"Hu","year":"2021","journal-title":"Ind. Eng. Chem. Res."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0390","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2024.114112","article-title":"ROS responsive hydrogel for inhibition of MUC5AC against allergic rhinitis: a new delivery strategy for ipratropium bromide","volume":"242","author":"Zhao","year":"2024","journal-title":"Colloid Surface B"},{"issue":"6","key":"10.1016\/j.ijbiomac.2025.147264_bb0395","doi-asserted-by":"crossref","DOI":"10.3390\/gels8060360","article-title":"Poloxamer-based scaffolds for tissue engineering applications: a review","volume":"8","author":"Cui","year":"2022","journal-title":"Gels"},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0400","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0927-7757(94)03028-X","article-title":"Poly(ethylene oxide) poly(propylene oxide) poly(ethylene oxide) block copolymer surfactants in aqueous solutions and at interfaces: thermodynamics, structure, dynamics, and modeling","volume":"96","author":"Alexandridis","year":"1995","journal-title":"Colloids Surf. A Physicochem. Eng. Asp."},{"issue":"10","key":"10.1016\/j.ijbiomac.2025.147264_bb0405","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1002\/pi.6266","article-title":"Pre-clinical and clinical applications of thermoreversible hydrogels in biomedical engineering: a review","volume":"70","author":"Constantinou","year":"2021","journal-title":"Polym. Int."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0410","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0939-6411(03)00095-X","article-title":"A thermosensitive chitosan-based hydrogel for the local delivery of paclitaxel","volume":"57","author":"Ruel-Gariepy","year":"2004","journal-title":"Eur. J. Pharm. Biopharm.\u202f: Off. J. Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik eV"},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0415","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.bpc.2005.03.009","article-title":"Morphology and gelation of thermosensitive chitosan hydrogels","volume":"117","author":"Crompton","year":"2005","journal-title":"Biophys. Chem."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0420","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.carbpol.2014.09.094","article-title":"Glycerophosphate-based chitosan thermosensitive hydrogels and their biomedical applications","volume":"117","author":"Zhou","year":"2015","journal-title":"Carbohyd. Polym."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0425","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.143136","article-title":"A thermosensitive chitosan hydrogel loaded with Thonningianin a nanoparticles promotes diabetic wound healing by modulating oxidative stress and angiogenesis","volume":"310","author":"Yun","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"9","key":"10.1016\/j.ijbiomac.2025.147264_bb0430","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s00403-006-0713-x","article-title":"Influence of pH on wound-healing: a new perspective for wound-therapy?","volume":"298","author":"Schneider","year":"2007","journal-title":"Arch. Dermatol. Res."},{"issue":"11","key":"10.1016\/j.ijbiomac.2025.147264_bb0435","doi-asserted-by":"crossref","first-page":"719","DOI":"10.4155\/tde-2019-0066","article-title":"Challenges and opportunities of pH in chronic wounds","volume":"10","author":"Wallace","year":"2019","journal-title":"Ther. Deliv."},{"issue":"10","key":"10.1016\/j.ijbiomac.2025.147264_bb0440","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S1359-6446(02)02255-9","article-title":"Hydrogels: from controlled release to pH-responsive drug delivery","volume":"7","author":"Gupta","year":"2002","journal-title":"Drug Discov. Today"},{"issue":"17-18","key":"10.1016\/j.ijbiomac.2025.147264_bb0445","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1177\/00405175241305543","article-title":"Recent developments and applications of pH-responsive polymers","volume":"95","author":"Yang","year":"2025","journal-title":"Text. Res. J."},{"issue":"23","key":"10.1016\/j.ijbiomac.2025.147264_bb0450","doi-asserted-by":"crossref","first-page":"6439","DOI":"10.1039\/D3MA00430A","article-title":"Stimuli-responsive chitosan-based injectable hydrogel for \u201con-demand\u201d drug release","volume":"4","author":"Wang","year":"2023","journal-title":"Mater. Adv."},{"issue":"Pt 3","key":"10.1016\/j.ijbiomac.2025.147264_bb0455","article-title":"Recent advances on chitosan\/hyaluronic acid-based stimuli-responsive hydrogels and composites for cancer treatment: a comprehensive review","volume":"280","author":"Alsaikhan","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"issue":"Pt 1","key":"10.1016\/j.ijbiomac.2025.147264_bb0460","article-title":"Reactive oxygen species-responsive hydrophobic crosslinked chitosan films based on triple-function crosslinkers","volume":"257","author":"Liu","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0465","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2025.159537","article-title":"Wound microenvironment sensing and self-adjusting hydrogel with glucose, ROS, and MMP-9 responsiveness for improving microcirculation of diabetes foot ulcers","volume":"505","author":"Yuan","year":"2025","journal-title":"Chem. Eng. J."},{"issue":"43","key":"10.1016\/j.ijbiomac.2025.147264_bb0470","doi-asserted-by":"crossref","first-page":"37563","DOI":"10.1021\/acsami.7b09395","article-title":"pH and glucose dual-responsive injectable hydrogels with insulin and fibroblasts as bioactive dressings for diabetic wound healing","volume":"9","author":"Zhao","year":"2017","journal-title":"Acs Appl. Mater. Interfaces"},{"issue":"40","key":"10.1016\/j.ijbiomac.2025.147264_bb0475","doi-asserted-by":"crossref","DOI":"10.1039\/D4TB00670D","article-title":"Modelling methacrylated chitosan hydrogel properties through an experimental design approach: from composition to material properties","volume":"12","author":"Bucciarelli","year":"2024","journal-title":"J. Mater. Chem. B"},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.147264_bb0480","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1002\/macp.200900385","article-title":"Exploring the factors affecting the solubility of chitosan in water","volume":"211","author":"Sogias","year":"2010","journal-title":"Macromol. Chem. Phys."},{"issue":"3","key":"10.1016\/j.ijbiomac.2025.147264_bb0485","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.carbpol.2005.09.023","article-title":"Water-solubility of chitosan and its antimicrobial activity","volume":"63","author":"Qin","year":"2006","journal-title":"Carbohyd. Polym."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0490","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2021.117768","article-title":"Chitosan hydrogels in 3D printing for biomedical applications","volume":"260","author":"Rajabi","year":"2021","journal-title":"Carbohydr. Polym."},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.147264_bb0495","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.eurpolymj.2012.12.009","article-title":"Chitosan-based biomaterials for tissue engineering","volume":"49","author":"Croisier","year":"2013","journal-title":"Eur. Polym. J."},{"issue":"7","key":"10.1016\/j.ijbiomac.2025.147264_bb0500","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.progpolymsci.2006.06.001","article-title":"Chitin and chitosan: properties and applications","volume":"31","author":"Rinaudo","year":"2006","journal-title":"Prog. Polym. Sci."},{"issue":"41","key":"10.1016\/j.ijbiomac.2025.147264_bb0505","doi-asserted-by":"crossref","first-page":"8245","DOI":"10.1039\/C4SM01336K","article-title":"Thermal gelation of chitosan in an aqueous alkali\u2013urea solution","volume":"10","author":"Li","year":"2014","journal-title":"Soft Matter"},{"issue":"26","key":"10.1016\/j.ijbiomac.2025.147264_bb0510","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.201701100","article-title":"Extremely strong and transparent chitin films: a high-efficiency, energy-saving, and \u201cgreen\u201d route using an aqueous KOH\/urea solution","volume":"27","author":"Huang","year":"2017","journal-title":"Adv. Funct. Mater."},{"issue":"18","key":"10.1016\/j.ijbiomac.2025.147264_bb0515","doi-asserted-by":"crossref","first-page":"5020","DOI":"10.1039\/D0BM00896F","article-title":"3D printing of high-strength chitosan hydrogel scaffolds without any organic solvents","volume":"8","author":"Zhou","year":"2020","journal-title":"Biomater. Sci.-Uk"},{"issue":"10","key":"10.1016\/j.ijbiomac.2025.147264_bb0520","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1021\/acsbiomaterials.6b00149","article-title":"New visible-light Photoinitiating system for improved print Fidelity in gelatin-based bioinks","volume":"2","author":"Lim","year":"2016","journal-title":"ACS Biomater Sci. Eng."},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.147264_bb0525","doi-asserted-by":"crossref","DOI":"10.1002\/bip.23080","article-title":"Differentiation potential of human adipose stem cells bioprinted with hyaluronic acid\/gelatin-based bioink through microextrusion and visible light-initiated crosslinking","volume":"109","author":"Sakai","year":"2018","journal-title":"Biopolymers"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0530","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.actbio.2020.12.051","article-title":"An injectable, self-healing phenol-functionalized chitosan hydrogel with fast gelling property and visible light-crosslinking capability for 3D printing","volume":"122","author":"Liu","year":"2021","journal-title":"Acta Biomater."},{"issue":"6","key":"10.1016\/j.ijbiomac.2025.147264_bb0535","doi-asserted-by":"crossref","DOI":"10.1016\/j.cclet.2023.108889","article-title":"Drug-loading ZIF-8 for modification of microporous bone scaffold to promote vascularized bone regeneration","volume":"35","author":"Zhang","year":"2024","journal-title":"Chinese Chem. Lett."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0540","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.2147\/IJN.S505918","article-title":"Injectable nanocomposite hydrogel for accelerating diabetic wound healing through inflammatory microenvironment regulation","volume":"20","author":"Chen","year":"2025","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0545","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.jconrel.2023.06.002","article-title":"Zeolitic imidazolate frameworks: from bactericidal properties to tissue regeneration","volume":"359","author":"Kermanian","year":"2023","journal-title":"J. Control. Release"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0550","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/j.jcis.2024.07.087","article-title":"Zeolitic imidazolate framework-8@polydopamine decorated carboxylated chitosan hydrogel with photocatalytic and photothermal antibacterial activity for infected wound healing","volume":"675","author":"Wang","year":"2024","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0555","doi-asserted-by":"crossref","DOI":"10.1016\/j.apsusc.2021.152120","article-title":"Polydopamine-stabilized ZIF-8: improved water stability and lubrication performance","volume":"578","author":"Tian","year":"2022","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0560","article-title":"Surface modification strategies and the functional mechanisms of gold nanozyme in biosensing and bioassay","volume":"20","author":"Garehbaghi","year":"2023","journal-title":"Mater. Today Bio"},{"issue":"5","key":"10.1016\/j.ijbiomac.2025.147264_bb0565","article-title":"Injectable light-responsive hydrogel dressing promotes diabetic wound healing by enhancing wound angiogenesis and inhibiting inflammation","volume":"17","author":"Ma","year":"2025","journal-title":"Polymers-Basel"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0570","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2024.124761","article-title":"Curcumin-loaded gold nanoparticles with enhanced antibacterial efficacy and wound healing properties in diabetic rats","volume":"666","author":"Salama","year":"2024","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0575","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.137746","article-title":"Construction of multifunctional hydrogel containing pH-responsive gold nanozyme for bacteria-infected wound healing","volume":"283","author":"Peng","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0580","doi-asserted-by":"crossref","DOI":"10.3390\/md20010056","article-title":"Green synthesis of silver nanoparticles by the Cyanobacteria sp.: characterization, antimicrobial and diabetic wound-healing actions","volume":"20","author":"Younis","year":"2022","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0585","article-title":"Hydrogel dressing composed of nanoAg@QAC promotes the healing of bacterial infected diabetic wounds","volume":"169","author":"Zhou","year":"2025","journal-title":"Biomater. Adv."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0590","article-title":"Microfibrillated cellulose-enhanced carboxymethyl chitosan\/oxidized starch sponge for chronic diabetic wound repair","volume":"135","author":"Long","year":"2022","journal-title":"Biomater. Adv."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0595","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2025.123316","article-title":"Multifunctional dynamic chitosan-guar gum nanocomposite hydrogels in infection and diabetic wound healing","volume":"354","author":"He","year":"2025","journal-title":"Carbohyd. Polym."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0600","doi-asserted-by":"crossref","DOI":"10.1007\/s12668-024-01606-7","article-title":"Fabrication and characterization of ZnO nanoparticle-loaded nanofibers for diabetic wound healing applications: an in vivo study","volume":"15","author":"Rastegar","year":"2025","journal-title":"Bionanoscience"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0605","doi-asserted-by":"crossref","first-page":"6843","DOI":"10.2147\/IJN.S388264","article-title":"Ecm mimicking biodegradable nanofibrous scaffold enriched with curcumin\/ZnO to accelerate diabetic wound healing via multifunctional bioactivity","volume":"17","author":"Yadav","year":"2022","journal-title":"Int. J. Nanomed."},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.147264_bb0610","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1021\/acsbiomaterials.3c01770","article-title":"Multifunctional MXene-based platforms for soft and bone tissue regeneration and engineering","volume":"10","author":"Iravani","year":"2024","journal-title":"ACS Biomater Sci. Eng."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0615","doi-asserted-by":"crossref","DOI":"10.1186\/s12951-024-02621-2","article-title":"NIR-responsive electrospun nanofiber dressing promotes diabetic-infected wound healing with programmed combined temperature-coordinated photothermal therapy","volume":"22","author":"Fu","year":"2024","journal-title":"J. Nanobiotechnol."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0620","doi-asserted-by":"crossref","DOI":"10.1186\/s12951-024-02799-5","article-title":"Endogenous electric field coupling Mxene sponge for diabetic wound management: haemostatic, antibacterial, and healing","volume":"22","author":"Zhou","year":"2024","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0625","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2022.865059","article-title":"Multifunctional Arabinoxylan-functionalized-graphene oxide based composite hydrogel for skin tissue engineering","volume":"10","author":"Khan","year":"2022","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"43","key":"10.1016\/j.ijbiomac.2025.147264_bb0630","doi-asserted-by":"crossref","first-page":"40024","DOI":"10.1021\/acsomega.2c06825","article-title":"Graphene oxide-functionalized bacterial cellulose-gelatin hydrogel with curcumin release and kinetics: in vitro biological evaluation","volume":"8","author":"Khan","year":"2023","journal-title":"ACS Omega"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0635","doi-asserted-by":"crossref","DOI":"10.1016\/j.compositesb.2023.110985","article-title":"Photothermal antibacterial antioxidant conductive self-healing hydrogel with nitric oxide release accelerates diabetic wound healing","volume":"266","author":"He","year":"2023","journal-title":"Compos. Part B-Eng."},{"issue":"13","key":"10.1016\/j.ijbiomac.2025.147264_bb0640","first-page":"1759","article-title":"Bioinspired reduced graphene oxide based Nanohybrids for Photocatalysis and antibacterial applications","volume":"22","author":"Umekar","year":"2021","journal-title":"Curr. Pharm. Biotechnol."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0645","article-title":"Polydopamine reduced graphene oxide\/ chitosan-based hydrogel for the therapy of diabetic wound","volume":"39","author":"Li","year":"2024","journal-title":"Mater. Today Commun."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0650","doi-asserted-by":"crossref","DOI":"10.1186\/s12967-022-03479-4","article-title":"Transdermal deferoxamine administration improves excisional wound healing in chronically irradiated murine skin","volume":"20","author":"Lintel","year":"2022","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0655","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.127213","article-title":"A temperature and pH dual-responsive injectable self-healing hydrogel prepared by chitosan oligosaccharide and aldehyde hyaluronic acid for promoting diabetic foot ulcer healing","volume":"253","author":"Tang","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"issue":"15","key":"10.1016\/j.ijbiomac.2025.147264_bb0660","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202500810","article-title":"pH and glucose dual-responsive hydrogels promoted diabetic wound healing by remodeling the wound microenvironment","volume":"14","author":"Zhou","year":"2025","journal-title":"Adv. Healthc. Mater."},{"issue":"11","key":"10.1016\/j.ijbiomac.2025.147264_bb0665","first-page":"14678","article-title":"Gastrointestinal pH-sensitive Pickering emulsions stabilized by Zein nanoparticles coated with bioactive Glycyrrhizic acid for improving Oral bioaccessibility of curcumin","volume":"15","author":"Li","year":"2023","journal-title":"Acs Appl. Mater. Interfaces"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0670","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2020.126273","article-title":"Hierarchical micro\/nanofibrous scaffolds incorporated with curcumin and zinc ion eutectic metal organic frameworks for enhanced diabetic wound healing via anti-oxidant and anti-inflammatory activities","volume":"402","author":"Wang","year":"2020","journal-title":"Chem. Eng. J."},{"issue":"8","key":"10.1016\/j.ijbiomac.2025.147264_bb0675","doi-asserted-by":"crossref","first-page":"9749","DOI":"10.1021\/acsami.3c16837","article-title":"A multifunctional, tough, stretchable, and transparent curcumin hydrogel with potent antimicrobial, Antioxidative, anti-inflammatory, and angiogenesis capabilities for diabetic wound healing","volume":"16","author":"Fan","year":"2024","journal-title":"Acs Appl. Mater. Interfaces"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0680","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/j.ijbiomac.2022.11.307","article-title":"Chitosan and carboxymethyl cellulose-based 3D multifunctional bioactive hydrogels loaded with nano-curcumin for synergistic diabetic wound repair","volume":"227","author":"Shah","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"issue":"3","key":"10.1016\/j.ijbiomac.2025.147264_bb0685","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/j.1600-079X.2006.00416.x","article-title":"Chronic melatonin treatment reduces the age-dependent inflammatory process in senescence-accelerated mice","volume":"42","author":"Rodr\u00edguez","year":"2007","journal-title":"J. Pineal Res."},{"issue":"3","key":"10.1016\/j.ijbiomac.2025.147264_bb0690","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/j.1600-079X.2011.00941.x","article-title":"Pain in neonatal intensive care: role of melatonin as an analgesic antioxidant","volume":"52","author":"Gitto","year":"2012","journal-title":"J. Pineal Res."},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.147264_bb0695","doi-asserted-by":"crossref","DOI":"10.1111\/jpi.12547","article-title":"Melatonin in macrophage biology: current understanding and future perspectives","volume":"66","author":"Xia","year":"2019","journal-title":"J. Pineal Res."},{"issue":"36","key":"10.1016\/j.ijbiomac.2025.147264_bb0700","article-title":"Nanomelatonin triggers superior anticancer functionality in a human malignant glioblastoma cell line","volume":"28","author":"Yadav","year":"2017","journal-title":"Nanotechnology"},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0705","doi-asserted-by":"crossref","DOI":"10.1186\/s13568-025-01854-0","article-title":"Treatment of -infected diabetic wounds by melatonin loaded nanocarriers","volume":"15","author":"Farid","year":"2025","journal-title":"AMB Express"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0710","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.actbio.2025.02.013","article-title":"Multifunctional nanodrug for simultaneously combating chemoresistance and immunosuppression in -associated colorectal cancer","volume":"195","author":"Li","year":"2025","journal-title":"Acta Biomater."},{"issue":"25","key":"10.1016\/j.ijbiomac.2025.147264_bb0715","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202316145","article-title":"Metformin-mediated immunosuppressive microenvironment remodeling in combination with chemotherapy via a spatial-specific multi-responsive carrier-free self-assembled nanoparticle","volume":"34","author":"Song","year":"2024","journal-title":"Adv. Funct. Mater."},{"issue":"10","key":"10.1016\/j.ijbiomac.2025.147264_bb0720","doi-asserted-by":"crossref","first-page":"6668","DOI":"10.1021\/acsomega.7b01067","article-title":"Tannic acid-based multifunctional hydrogels with facile adjustable adhesion and cohesion contributed by polyphenol supramolecular chemistry","volume":"2","author":"Fan","year":"2017","journal-title":"ACS Omega"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0725","article-title":"Hydrogel inspired by \u201cadobe\u201d with antibacterial and antioxidant properties for diabetic wound healing","volume":"31","author":"Li","year":"2025","journal-title":"Mater. Today Bio."},{"issue":"18","key":"10.1016\/j.ijbiomac.2025.147264_bb0730","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202304536","article-title":"Hybrid hydrogels for Immunoregulation and Proangiogenesis through mild heat stimulation to accelerate whole-process diabetic wound healing","volume":"13","author":"Guo","year":"2024","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0735","article-title":"A fabric-reinforced polysaccharide-based hydrogel with conductive, adhesive, antibacterial and anti-inflammatory for monitoring and treatment of diabetic wounds","volume":"44","author":"Shen","year":"2025","journal-title":"Appl. Mater. Today"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0740","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2025.159537","article-title":"Wound microenvironment sensing and self-adjusting hydrogel with glucose, ROS, and MMP-9 responsiveness for improving microcirculation of diabetes foot ulcers","volume":"505","author":"Yuan","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0745","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.jconrel.2023.05.047","article-title":"A glucose-responsive nitric oxide release hydrogel for infected diabetic wounds treatment","volume":"359","author":"Zhou","year":"2023","journal-title":"J. Control. Release"},{"issue":"7","key":"10.1016\/j.ijbiomac.2025.147264_bb0750","article-title":"Exos-loaded Gox-modified smart-response self-healing hydrogel improves the microenvironment and promotes wound healing in diabetic wounds","volume":"14","author":"Yang","year":"2025","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0755","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.913408","article-title":"Chitosan\/sodium alginate\/velvet antler blood peptides hydrogel promoted wound healing by regulating PI3K\/AKT\/mTOR and SIRT1\/NF-\u03baB pathways","volume":"13","author":"Hao","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0760","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.116076","article-title":"Multifunctional biomaterial hydrogel loaded with antler blood peptide effectively promotes wound repair","volume":"170","author":"Ma","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0765","doi-asserted-by":"crossref","first-page":"4921","DOI":"10.2147\/JIR.S376692","article-title":"Chitosan\/sodium alginate\/velvet antler blood peptides hydrogel promotes diabetic wound healing via regulating angiogenesis, inflammatory response and skin flora","volume":"15","author":"Hao","year":"2022","journal-title":"J. Inflamm. Res."},{"issue":"5","key":"10.1016\/j.ijbiomac.2025.147264_bb0770","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1080\/09205063.2021.2002235","article-title":"VEGF loaded porcine decellularized adipose tissue derived hydrogel could enhance angiogenesis in vitro and in vivo","volume":"33","author":"Liu","year":"2022","journal-title":"J. Biomat. Sci.-Polym. E"},{"issue":"3","key":"10.1016\/j.ijbiomac.2025.147264_bb0775","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1152\/physrev.2003.83.3.835","article-title":"Regulation of wound healing by growth factors and cytokines","volume":"83","author":"Werner","year":"2003","journal-title":"Physiol. Rev."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0780","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/nrd2399","article-title":"Protein therapeutics: a summary and pharmacological classification","volume":"7","author":"Leader","year":"2008","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0785","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.actbio.2024.09.045","article-title":"A biphasic drug-releasing microneedle with ROS scavenging and angiogenesis for the treatment of diabetic ulcers","volume":"189","author":"He","year":"2024","journal-title":"Acta Biomater."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0790","doi-asserted-by":"crossref","DOI":"10.1186\/s13287-016-0418-9","article-title":"Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta","volume":"7","author":"Du","year":"2016","journal-title":"Stem Cell Res. Ther."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0795","doi-asserted-by":"crossref","DOI":"10.1186\/s13287-021-02657-3","article-title":"Recent strategies for enhancing the therapeutic efficacy of stem cells in wound healing","volume":"12","author":"Zhao","year":"2021","journal-title":"Stem Cell Res. Ther."},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.147264_bb0800","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1159\/000381877","article-title":"Stem cells in wound healing: the future of regenerative medicine? A mini-review","volume":"62","author":"Duscher","year":"2016","journal-title":"Gerontology"},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0805","doi-asserted-by":"crossref","DOI":"10.1186\/scrt324","article-title":"Mesenchymal stem cells modified with angiopoietin-1 gene promote wound healing","volume":"4","author":"Li","year":"2013","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.ijbiomac.2025.147264_bb0810","article-title":"Hydrogel patch with pretreated stem cells accelerates wound closure in diabetic rats","volume":"142","author":"Andleeb","year":"2022","journal-title":"Biomater Adv."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.147264_bb0815","doi-asserted-by":"crossref","first-page":"605","DOI":"10.3390\/ijms15010605","article-title":"Hypoxic conditioned medium from human amniotic fluid-derived mesenchymal stem cells accelerates skin wound healing through TGF-\u03b2\/SMAD2 and PI3K\/Akt pathways","volume":"15","author":"Jun","year":"2014","journal-title":"Int. J. Mol. Sci."}],"container-title":["International Journal of Biological Macromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813025078213?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813025078213?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T23:53:18Z","timestamp":1757289198000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0141813025078213"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":163,"alternative-id":["S0141813025078213"],"URL":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2025.147264","relation":{},"ISSN":["0141-8130"],"issn-type":[{"value":"0141-8130","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Applications of chitosan-based hydrogels in diabetic wound healing: A review","name":"articletitle","label":"Article Title"},{"value":"International Journal of Biological Macromolecules","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2025.147264","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"147264"}}