{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,15]],"date-time":"2026-11-15T04:57:42Z","timestamp":1794718662731,"version":"4.9.1"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biological Macromolecules"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.ijbiomac.2025.149140","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T13:44:23Z","timestamp":1763646263000},"page":"149140","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"P2","title":["Myco\u2013macromolecular symbiosis: Chitosan\u2013folate ZnO nanoplatforms from Trametes versicolor for dual-functional oncological and antibacterial therapy"],"prefix":"10.1016","volume":"334","author":[{"given":"Mojtaba","family":"Ranjbar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masumeh","family":"Ahmadpour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud","family":"Kiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mostafa","family":"Govahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.ijbiomac.2025.149140_bb0005","doi-asserted-by":"crossref","first-page":"2274","DOI":"10.1007\/s11427-024-2657-y","article-title":"Understanding the global cancer statistics 2022: growing cancer burden","volume":"67","author":"Liu","year":"2024","journal-title":"Sci. China Life Sci."},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0010","doi-asserted-by":"crossref","DOI":"10.12659\/MSM.945583","article-title":"The global threats of increasing antimicrobial resistance require new approaches to drug development, including molecular antimicrobial adjuvants","volume":"30","author":"Parums","year":"2024","journal-title":"Medical Science Monitor: International Medical Journal of Experimental and Clinical Research"},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0015","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.trsl.2021.12.001","article-title":"Immune mechanisms in cancer patients that lead to poor outcomes of SARS-CoV-2 infection","volume":"241","author":"Latif","year":"2022","journal-title":"Transl. Res."},{"issue":"6","key":"10.1016\/j.ijbiomac.2025.149140_bb0020","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1016\/j.apt.2021.04.014","article-title":"Green synthesis of zinc oxide nanoparticles using Amygdalus scoparia Spach stem bark extract and their applications as an alternative antimicrobial, anticancer, and anti-diabetic agent","volume":"32","author":"Jobie","year":"2021","journal-title":"Adv. Powder Technol."},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.jddst.2020.102042","article-title":"Mentha mozaffarianii mediated biogenic zinc nanoparticles target selected cancer cell lines and microbial pathogens","volume":"60","author":"Ranjbar","year":"2020","journal-title":"Journal of Drug Delivery Science and Technology"},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0030","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.cis.2017.07.033","article-title":"Zinc oxide nanoparticles: synthesis, antiseptic activity and toxicity mechanism","volume":"249","author":"Kr\u00f3l","year":"2017","journal-title":"Adv. Colloid Interf. Sci."},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadva.2022.100051","article-title":"Application of zinc oxide nanoflowers in environmental and biomedical science","volume":"2","author":"Raj","year":"2022","journal-title":"BBA advances"},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.149140_bb0040","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.ipha.2024.08.004","article-title":"A critical review on zinc oxide nanoparticles: synthesis, properties and biomedical applications","volume":"3","author":"Dey","year":"2025","journal-title":"Intelligent Pharmacy"},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.149140_bb0045","doi-asserted-by":"crossref","first-page":"525","DOI":"10.2131\/jts.38.525","article-title":"Exposure to zinc oxide nanoparticles affects reproductive development and biodistribution in offspring rats","volume":"38","author":"Jo","year":"2013","journal-title":"J. Toxicol. Sci."},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtemb.2024.127411","article-title":"Exposure to zinc oxide nanoparticles induced reproductive toxicities in male Sprague Dawley rats","volume":"83","author":"Rehman","year":"2024","journal-title":"J. Trace Elem. Med. Biol."},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.149140_bb0055","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0734-9750(03)00002-8","article-title":"Polysaccharopeptides of Coriolus versicolor: physiological activity, uses, and production","volume":"21","author":"Cui","year":"2003","journal-title":"Biotechnol. Adv."},{"issue":"16","key":"10.1016\/j.ijbiomac.2025.149140_bb0060","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1080\/14786419.2018.1446011","article-title":"Anti-inflammatory activities of the chemical constituents isolated from Trametes versicolor","volume":"33","author":"Jin","year":"2019","journal-title":"Nat. Prod. Res."},{"issue":"3","key":"10.1016\/j.ijbiomac.2025.149140_bb0065","first-page":"93","article-title":"Effect of aqueous extract of Turkey tail (Trametes versicolor) on Staphylococcus aureus, Escherichia coli and fusarium thapsinum","volume":"24","author":"Ahmadpour Torki","year":"2022","journal-title":"Journal of Gorgan University of Medical Sciences"},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0070","article-title":"Starch-functionalized Berberis-ZnO nanoparticles: folic acid-gemcitabine delivery and ceftriaxone release for targeted cancer therapy and antibacterial applications","volume":"112","author":"Ranjbar","year":"2025","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.138619","article-title":"Green synthesis of silver nanoparticles (AgNPs) and chitosan-coated silver nanoparticles (CS-AgNPs) using Ferula gummosa Boiss. Gum extract: A green nano drug for potential applications in medicine","volume":"291","author":"Ghasemi","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"3","key":"10.1016\/j.ijbiomac.2025.149140_bb0080","doi-asserted-by":"crossref","first-page":"330","DOI":"10.3390\/molecules21030330","article-title":"Chitosan and its derivatives as highly efficient polymer ligands","volume":"21","author":"Pestov","year":"2016","journal-title":"Molecules"},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.149140_bb0085","doi-asserted-by":"crossref","first-page":"443","DOI":"10.31557\/APJCP.2025.26.2.443","article-title":"In vitro evaluation of zinc oxide-metformin folic acid nanocomposite as a targeted drug delivery system for cancer therapy","volume":"26","author":"Ezzat","year":"2025","journal-title":"Asian Pacific Journal of Cancer Prevention: APJCP"},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0090","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jconrel.2016.06.021","article-title":"Dual CD44 and folate receptor-targeted nanoparticles for cancer diagnosis and anticancer drug delivery","volume":"236","author":"Lee","year":"2016","journal-title":"J. Control. Release"},{"issue":"6","key":"10.1016\/j.ijbiomac.2025.149140_bb0095","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1586\/14737140.7.6.833","article-title":"Nanotechnology for targeted cancer therapy","volume":"7","author":"Wang","year":"2007","journal-title":"Expert. Rev. Anticancer. Ther."},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.149140_bb0100","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.ijpharm.2013.11.035","article-title":"Synthesis and characterization of a novel controlled release zinc oxide\/gentamicin\u2013chitosan composite with potential applications in wounds care","volume":"463","author":"Vasile","year":"2014","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0105","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.ijbiomac.2021.12.070","article-title":"Folate functionalized chitosan nanoparticles as targeted delivery systems for improved anticancer efficiency of cytarabine in MCF-7 human breast cancer cell lines","volume":"199","author":"Geethakumari","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"issue":"3","key":"10.1016\/j.ijbiomac.2025.149140_bb0110","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1177\/0960327119888270","article-title":"Green synthesis of ZnO nanoparticles with Veronica multifida and their antibiofilm activity","volume":"39","author":"Do\u011fan","year":"2020","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2021.111897","article-title":"Green synthesis, characterization and bioactivity of biogenic zinc oxide nanoparticles","volume":"204","author":"Gur","year":"2022","journal-title":"Environ. Res."},{"issue":"19","key":"10.1016\/j.ijbiomac.2025.149140_bb0120","doi-asserted-by":"crossref","first-page":"4521","DOI":"10.3390\/molecules25194521","article-title":"Green synthesis of zinc oxide nanoparticles from pomegranate (Punica granatum) extracts and characterization of their antibacterial activity","volume":"25","author":"Ifeanyichukwu","year":"2020","journal-title":"Molecules"},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.149140_bb0125","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s10876-024-02760-4","article-title":"Synthesis and characterization of chitosan\/zinc oxide nanocomposite for enhanced applications as antibacterial, antifungal and aflatoxin B1 adsorption","volume":"36","author":"Asghar","year":"2025","journal-title":"J. Clust. Sci."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.149140_bb0130","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s10008-021-05026-5","article-title":"UV\/Vis absorption spectroelectrochemistry of folic acid","volume":"26","author":"Olmo","year":"2022","journal-title":"J. Solid State Electrochem."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.149140_bb0135","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s10967-010-0661-y","article-title":"Preparation and biological evaluation of radiolabeled-folate embedded superparamagnetic nanoparticles in wild-type rats","volume":"287","author":"Jalilian","year":"2011","journal-title":"J. Radioanal. Nucl. Chem."},{"issue":"23","key":"10.1016\/j.ijbiomac.2025.149140_bb0140","doi-asserted-by":"crossref","first-page":"5237","DOI":"10.1021\/cm202278z","article-title":"Surface functionalization of zinc oxide nanoparticles: an investigation in the aerosol state","volume":"23","author":"Chiang","year":"2011","journal-title":"Chem. Mater."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.149140_bb0145","doi-asserted-by":"crossref","DOI":"10.3390\/nano11010095","article-title":"Green synthesis of zinc oxide nanoparticles (ZnO-NPs) using Arthrospira platensis (class: Cyanophyceae) and evaluation of their biomedical activities","volume":"11","author":"El-Belely","year":"2021","journal-title":"Nanomaterials"},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0150","first-page":"638","article-title":"Restriction of particle size and lattice strain through X-ray diffraction peak broadening analysis of ZnO nanoparticles","volume":"49","author":"Ihsan","year":"2015","journal-title":"Adv. Phys. Theor. Appl."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.149140_bb0155","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1021\/acsanm.9b01921","article-title":"Transferrin-conjugated polymer-coated mesoporous silica nanoparticles loaded with gemcitabine for killing pancreatic cancer cells","volume":"3","author":"Saini","year":"2019","journal-title":"ACS Applied Nano Materials"},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.eurpolymj.2020.109984","article-title":"Antibacterial activity of chitosan and its derivatives and their interaction mechanism with bacteria: current state and perspectives","volume":"138","author":"Li","year":"2020","journal-title":"Eur. Polym. J."},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.149140_bb0165","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1148\/radiol.10090050","article-title":"Breast cancers: MR imaging of folate-receptor expression with the folate-specific nanoparticle P1133","volume":"255","author":"Meier","year":"2010","journal-title":"Radiology"},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0170","series-title":"Enhanced Permeability And Retention Effect-Focused Tumor-Targeted Nanomedicines: Latest Trends, Obstacles And Future Perspective","first-page":"1213","volume":"17","author":"Shekhar","year":"2022"},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0175","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.carres.2014.01.024","article-title":"The synthesis of gemcitabine","volume":"387","author":"Brown","year":"2014","journal-title":"Carbohydr. Res."},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.149140_bb0180","doi-asserted-by":"crossref","first-page":"678","DOI":"10.3390\/nano10040678","article-title":"A multi-method approach for quantification of surface coatings on commercial zinc oxide nanomaterials","volume":"10","author":"Kunc","year":"2020","journal-title":"Nanomaterials"},{"issue":"12","key":"10.1016\/j.ijbiomac.2025.149140_bb0185","doi-asserted-by":"crossref","DOI":"10.3390\/molecules26123731","article-title":"The concept of folic acid in health and disease","volume":"26","author":"Shulpekova","year":"2021","journal-title":"Molecules"},{"issue":"12","key":"10.1016\/j.ijbiomac.2025.149140_bb0190","doi-asserted-by":"crossref","first-page":"2786","DOI":"10.1021\/acsearthspacechem.9b00253","article-title":"Overlooked role of carbonyls of natural organic matter on the dissolution of zinc oxide nanoparticles","volume":"3","author":"Zhang","year":"2019","journal-title":"ACS Earth and Space Chemistry"},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0195","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11051-012-0920-7","article-title":"Colloidal stability of polymeric nanoparticles in biological fluids","volume":"14","author":"Lazzari","year":"2012","journal-title":"J. Nanopart. Res."},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0200","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1007\/s11274-004-6559-5","article-title":"Cs interactions with metal ions and dyes: dissolved\u2013state vs. solid\u2013state application","volume":"21","author":"Guibal","year":"2005","journal-title":"World J. Microbiol. Biotechnol."},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.reactfunctpolym.2019.104459","article-title":"Cs as a coating material for nanoparticles intended for biomedical applications","volume":"147","author":"Frank","year":"2020","journal-title":"React. Funct. Polym."},{"issue":"5","key":"10.1016\/j.ijbiomac.2025.149140_bb0210","first-page":"911","article-title":"Folate receptor and its application in the selective receptor-mediated targeting therapy of tumor cells--review","volume":"13","author":"Gao","year":"2005","journal-title":"Zhongguo Shi Yan Xue Ye Xue Za Zhi."},{"issue":"7","key":"10.1016\/j.ijbiomac.2025.149140_bb0215","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1517\/17425247.2010.485983","article-title":"Cationic nanoparticles for cancer therapy","volume":"7","author":"Bilensoy","year":"2010","journal-title":"Expert Opin. Drug Deliv."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.149140_bb0220","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/s44259-023-00016-1","article-title":"Tackling the outer membrane: facilitating compound entry into gram-negative bacterial pathogens","volume":"1","author":"Saxena","year":"2023","journal-title":"npj Antimicrobials and Resistance"},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijfoodmicro.2020.108838","article-title":"Antimicrobial activity of chitosan coating containing ZnO nanoparticles against E. Coli O157: H7 on the surface of white brined cheese","volume":"334","author":"Al-Nabulsi","year":"2020","journal-title":"Int. J. Food Microbiol."},{"issue":"8","key":"10.1016\/j.ijbiomac.2025.149140_bb0230","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/j.carres.2010.03.019","article-title":"Synthesis and characterization of chitosan\/ZnO nanoparticle composite membranes","volume":"345","author":"Li","year":"2010","journal-title":"Carbohydr. Res."},{"issue":"14","key":"10.1016\/j.ijbiomac.2025.149140_bb0235","doi-asserted-by":"crossref","first-page":"1968","DOI":"10.1039\/c3tb00555k","article-title":"Chitosan and chitosan\u2013ZnO-based complex nanoparticles: formation, characterization, and antibacterial activity","volume":"1","author":"Perelshtein","year":"2013","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0240","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/j.ijbiomac.2018.11.228","article-title":"Synthesis of ZnO nanoparticles with chitosan as stabilizing agent and their antibacterial properties against gram-positive and gram-negative bacteria","volume":"124","author":"Yusof","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"issue":"10","key":"10.1016\/j.ijbiomac.2025.149140_bb0245","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1093\/annonc\/mdv250","article-title":"Targeting the folate receptor: diagnostic and therapeutic approaches to personalize cancer treatments","volume":"26","author":"Ledermann","year":"2015","journal-title":"Ann. Oncol."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.149140_bb0250","doi-asserted-by":"crossref","first-page":"17513","DOI":"10.1038\/s41598-024-64610-7","article-title":"Targeting vascular disrupting agent-treated tumor microenvironment with tissue-penetrating nanotherapy","volume":"14","author":"Sidorenko","year":"2024","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.149140_bb0255","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.jsps.2017.12.010","article-title":"Chitosan-based zinc oxide nanoparticle for enhanced anticancer effect in cervical cancer: A physicochemical and biological perspective","volume":"26","author":"Wu","year":"2018","journal-title":"Saudi Pharmaceutical Journal"},{"issue":"12","key":"10.1016\/j.ijbiomac.2025.149140_bb0260","doi-asserted-by":"crossref","DOI":"10.3390\/biom11121850","article-title":"CD44: a multifunctional mediator of cancer progression","volume":"11","author":"Hassn Mesrati","year":"2021","journal-title":"Biomolecules"},{"issue":"4","key":"10.1016\/j.ijbiomac.2025.149140_bb0265","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1242\/jcs.092734","article-title":"\u0392-Catenin\u2013SOX2 signaling regulates the fate of developing airway epithelium","volume":"125","author":"Hashimoto","year":"2012","journal-title":"J. Cell Sci."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.149140_bb0270","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/dvdy.22046","article-title":"Interactions between SOX factors and Wnt\/\u03b2-catenin signaling in development and disease","volume":"239","author":"Kormish","year":"2010","journal-title":"Developmental dynamics: an official publication of the American Association of Anatomists"},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0275","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2021.642719","article-title":"Could we address the interplay between CD133, Wnt\/\u03b2-catenin, and TERT signaling pathways as a potential target for glioblastoma therapy?","volume":"11","author":"Behrooz","year":"2021","journal-title":"Front. Oncol."},{"issue":"2","key":"10.1016\/j.ijbiomac.2025.149140_bb0280","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/sj.cdd.4400476","article-title":"Emerging roles of caspase-3 in apoptosis","volume":"6","author":"Porter","year":"1999","journal-title":"Cell Death Differ."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.149140_bb0285","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/cbdd.13860","article-title":"Caspase-3: A primary target for natural and synthetic compounds for cancer therapy","volume":"98","author":"Yadav","year":"2021","journal-title":"Chem. Biol. Drug Des."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.149140_bb0290","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.canlet.2005.06.004","article-title":"Roles and regulation of Wnt signaling and \u03b2-catenin in prostate cancer","volume":"237","author":"Verras","year":"2006","journal-title":"Cancer Lett."},{"issue":"1","key":"10.1016\/j.ijbiomac.2025.149140_bb0295","doi-asserted-by":"crossref","first-page":"e311","DOI":"10.1097\/CAD.0000000000001207","article-title":"Anticancer properties of novel zinc oxide quantum dot nanoparticles against breast cancer stem-like cells","volume":"33","author":"Fakhroueian","year":"2022","journal-title":"Anti-Cancer Drugs"},{"issue":"46","key":"10.1016\/j.ijbiomac.2025.149140_bb0300","doi-asserted-by":"crossref","first-page":"39971","DOI":"10.1021\/acsami.7b11219","article-title":"Exploration of zinc oxide nanoparticles as a multitarget and multifunctional anticancer nanomedicine","volume":"9","author":"Wang","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0305","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ijbiomac.2020.02.106","article-title":"Folate receptor alpha targeted delivery of artemether to breast cancer cells with folate-decorated human serum albumin nanoparticles","volume":"152","author":"Akbarian","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2025.149140_bb0310","doi-asserted-by":"crossref","DOI":"10.1016\/j.jphotobiol.2020.111918","article-title":"Evaluating internalization and recycling of folate receptors in breast cancer cells using quantum dots","volume":"209","author":"Monteiro","year":"2020","journal-title":"J. Photochem. Photobiol. B Biol."}],"container-title":["International Journal of Biological Macromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813025096977?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813025096977?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T08:45:39Z","timestamp":1781167539000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0141813025096977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":62,"alternative-id":["S0141813025096977"],"URL":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2025.149140","relation":{},"ISSN":["0141-8130"],"issn-type":[{"value":"0141-8130","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Myco\u2013macromolecular symbiosis: Chitosan\u2013folate ZnO nanoplatforms from Trametes versicolor for dual-functional oncological and antibacterial therapy","name":"articletitle","label":"Article Title"},{"value":"International Journal of Biological Macromolecules","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2025.149140","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"149140"}}