{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,12]],"date-time":"2026-11-12T15:21:05Z","timestamp":1794496865616,"version":"4.9.1"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biological Macromolecules"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.ijbiomac.2026.154208","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T23:36:08Z","timestamp":1788478568000},"page":"154208","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"P1","title":["Fucodain loaded on zinc oxide nanoparticles derived from Turbinaria ornata suppresses skin cancer proliferation and migration via modulation of EMT-related miRNAs"],"prefix":"10.1016","volume":"382","author":[{"given":"Mostafa M.","family":"El-Sheekh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eman","family":"Bases","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shimaa M.","family":"El Shafay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rania A.","family":"Elshenody","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdel Hady A.","family":"Abdel Wahab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wesam E.","family":"Yousuf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorya I.","family":"Essa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samar Sami","family":"Alkafaas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijbiomac.2026.154208_bb0005","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1186\/s12943-023-01854-3","article-title":"Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches","volume":"22","author":"Hasan","year":"2023","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0010","series-title":"Epidemiology of skin cancer\u202f: past, present and future","first-page":"19","author":"Federico","year":"2025"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0015","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26094364","article-title":"Molecular mechanisms regulating epithelial mesenchymal transition (EMT) to promote cancer progression","volume":"26","author":"Ghafoor","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0020","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1186\/s12967-025-06447-w","article-title":"Matrix metalloproteinase-driven epithelial-mesenchymal transition: implications in health and disease","volume":"23","author":"Khalili-Tanha","year":"2025","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0025","doi-asserted-by":"crossref","first-page":"9663","DOI":"10.1007\/s11033-023-08809-3","article-title":"Cancer treatment therapies: traditional to modern approaches to combat cancers","volume":"50","author":"Kaur","year":"2023","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0030","doi-asserted-by":"crossref","first-page":"7209","DOI":"10.1007\/s11033-020-05709-8","article-title":"Bioactive compounds from marine invertebrates as potent anticancer drugs: the possible pharmacophores modulating cell death pathways","volume":"47","author":"Patra","year":"2020","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0035","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics17070826","article-title":"Fucoidan-based gold nanoparticles: antioxidant and anticancer potential from Turbinaria decurrens and Sargassum cinereum","volume":"17","author":"Newehy","year":"2025","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.carres.2026.109893","article-title":"Fucoidan-based nanoparticles for colorectal cancer therapy: mechanisms and preclinical insights","volume":"564","author":"Pareek","year":"2026","journal-title":"Carbohydr. Res."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0045","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26189228","article-title":"Inhibitory effect of Fucoidan analogs on highly metastatic gastric cancer cells via Galectin-4 inhibition","volume":"26","author":"Ji","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0050","doi-asserted-by":"crossref","DOI":"10.1002\/cbdv.202401613","article-title":"Seaweed-derived bioactive compounds: potent modulators in breast cancer therapy","volume":"22","author":"Behera","year":"2025","journal-title":"Chem. Biodivers."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0055","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1658526","article-title":"Post-transcriptional regulation by HuR in colorectal cancer: impacts on tumor progression and therapeutic strategies","volume":"16","author":"Shi","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0060","doi-asserted-by":"crossref","DOI":"10.3390\/biology14010043","article-title":"Integrated analysis of microRNA targets reveals new insights into transcriptional\u2013post-transcriptional regulatory cross-talk","volume":"14","author":"Panni","year":"2025","journal-title":"Biology"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0065","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26178615","article-title":"Micro RNA in colorectal cancer\u2014potential diagnostic and prognostic markers\u2014an updated review","volume":"26","author":"Paj\u0105k","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0070","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1007\/s12032-025-03006-7","article-title":"miRNA-mediated resistance mechanisms in prostate cancer: implications for targeted therapy and metastatic progression","volume":"42","author":"Mostafa","year":"2025","journal-title":"Med. Oncol."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0075","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26083736","article-title":"The role of MicroRNAs in lung cancer: mechanisms, diagnostics and therapeutic potential","volume":"26","author":"Bartoszewska","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0080","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/B978-0-443-30225-1.00031-2","article-title":"Cervical cancer: new treatment approaches using microRNA","author":"Dbilen","year":"2026","journal-title":"Cancer Biomark. Oncoviruses"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0085","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s12041-021-01265-7","article-title":"A comprehensive review on oncogenic miRNAs in breast cancer","volume":"100","author":"Nurzadeh","year":"2021","journal-title":"J. Genet."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0090","doi-asserted-by":"crossref","DOI":"10.1002\/biof.2146","article-title":"Role of miRNAs in breast cancer development and progression: current research","volume":"51","author":"Kumar","year":"2025","journal-title":"Biofactors"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0095","article-title":"Exosomal miRNAs: key regulators of the tumor microenvironment and cancer stem cells","volume":"26","author":"Wang","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0100","first-page":"58012","article-title":"Fucoidan for lung cancer therapy: a review of classification, mechanisms, and preclinical studies","volume":"10","author":"Uyen","year":"2025","journal-title":"ACS Omega"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0105","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1186\/s12951-025-03473-0","article-title":"Fucoidan-decorated metal-zoledronic acid nanocomplexes suppress tumor metastasis by inducing ferroptotic cell death and enhancing cancer immunotherapy","volume":"23","author":"Tsai","year":"2025","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0110","doi-asserted-by":"crossref","DOI":"10.1002\/efd2.70085","article-title":"Fucoidan from brown algae as a functional food ingredient: a promising anticancer agent","volume":"6","author":"Khan","year":"2025","journal-title":"eFood"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0115","doi-asserted-by":"crossref","DOI":"10.3390\/md18030143","article-title":"Micro RNA expression after ingestion of fucoidan; a clinical study","volume":"18","author":"Gueven","year":"2020","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0120","article-title":"Seaweed-derived nanomaterials: a green nanotechnology approach toward one health\u2013oriented medical solutions","volume":"95","author":"Muthu-Pandian","year":"2026","journal-title":"Algal Res."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0125","doi-asserted-by":"crossref","DOI":"10.1002\/fsn3.71482","article-title":"Recent progressions in applications of bioactive polysaccharides in food and health sciences: a comprehensive review","volume":"14","author":"Chaitanya","year":"2026","journal-title":"Food Sci. Nutr."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0130","doi-asserted-by":"crossref","DOI":"10.3390\/ijms27031356","article-title":"Recent advancements in bioactive natural products and nanoparticle-mediated drug delivery in cancer therapy","volume":"27","author":"Bhajan","year":"2026","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0135","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.2174\/1871520620666200504071530","article-title":"Paclitaxel nanoparticles induce apoptosis and regulate txr1, cyp3a4 and cyp2c8 in breast cancer and hepatoma cells","volume":"20","author":"Diab","year":"2020","journal-title":"Anti Cancer Agents Med. Chem."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0140","doi-asserted-by":"crossref","DOI":"10.3390\/cancers13184570","article-title":"Recent advances in zinc oxide nanoparticles (ZnO NPs) for cancer diagnosis, target drug delivery, and treatment","volume":"13","author":"Anjum","year":"2021","journal-title":"Cancers"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0145","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1007\/s12672-025-02664-3","article-title":"Nanotechnology in oncology: advances in biosynthesis, drug delivery, and theranostics","volume":"16","author":"Ammar","year":"2025","journal-title":"Discov. Oncol."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0150","doi-asserted-by":"crossref","first-page":"3747","DOI":"10.1007\/s12010-022-03966-w","article-title":"Biotechnology, anti-dengue activity of ZnO nanoparticles of crude fucoidan from brown seaweed Sargassum marginatum","volume":"195","author":"Kothai","year":"2023","journal-title":"Appl. Biochem. Biotechnol."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2024.107776","article-title":"Targeting JNK kinase inhibitors via molecular docking: A promising strategy to address tumorigenesis and drug resistance","volume":"153","author":"Alkafaas","year":"2024","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0160","doi-asserted-by":"crossref","first-page":"5006","DOI":"10.1158\/0008-5472.CAN-15-2921","article-title":"Metabolic stress-induced phosphorylation of KAP1 Ser473 blocks mitochondrial fusion in breast cancer cells","volume":"76","author":"Cheng","year":"2016","journal-title":"Cancer Res."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2020.105295","article-title":"Repurposing of antipsychotic trifluoperazine for treating brain metastasis, lung metastasis and bone metastasis of melanoma by disrupting autophagy flux","volume":"163","author":"Xia","year":"2021","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0170","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1007\/s13204-021-01760-4","article-title":"The influence of fucoidan on stability, adsorption and electrokinetic properties of ZnO and TiO2 suspensions","volume":"12","author":"Matusiak","year":"2022","journal-title":"Appl. Nanosci."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0175","first-page":"811","article-title":"Synthesis, anticandidal potentiality of biosynthesized and decorated nanometals with fucoidan, green process","volume":"10","author":"Alghuthaymi","year":"2021","journal-title":"Synth"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0180","doi-asserted-by":"crossref","DOI":"10.1088\/2399-6528\/ac8049","article-title":"Characterization of low-temperature-grown ZnO nanoparticles: the effect of temperature on growth","volume":"6","author":"Dejene","year":"2022","journal-title":"J. Phys. Commun."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0185","doi-asserted-by":"crossref","DOI":"10.3390\/molecules23061429","article-title":"Preparation, characterization and biological applications of biosynthesized silver nanoparticles with chitosan-fucoidan coating","volume":"23","author":"Venkatesan","year":"2018","journal-title":"Molecules"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0190","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1080\/10408398.2022.2106182","article-title":"Fucoidan-based nanomaterial and its multifunctional role for pharmaceutical and biomedical applications","volume":"64","author":"Iqbal","year":"2024","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0195","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.jconrel.2016.06.017","article-title":"DLS and zeta potential\u2013what they are and what they are not?","volume":"235","author":"Bhattacharjee","year":"2016","journal-title":"J. Control. Release"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0200","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1080\/10408398.2021.1965537","article-title":"Nutrition, seaweed bioactive compounds: promising and safe inputs for the green synthesis of metal nanoparticles in the food industry","volume":"63","author":"Cassani","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0205","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1039\/D1NA00880C","article-title":"ZnO nanostructured materials and their potential applications: progress, challenges and perspectives","volume":"4","author":"Raha","year":"2022","journal-title":"Nanoscale Adv."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0210","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1039\/D5SU00014A","article-title":"Phyco-synthesized inorganic nanoparticles and their biomedical applications","volume":"3","author":"Ramaraj","year":"2025","journal-title":"RSC Sustain."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0215","doi-asserted-by":"crossref","first-page":"10809","DOI":"10.1021\/acsanm.2c02129","article-title":"Suppressing the agglomeration of ZnO nanoparticles in air by doping with lower electronegativity metallic ions: implications for Ag\/ZnO electrical contact composites","volume":"5","author":"Chen","year":"2022","journal-title":"ACS Appl. Nano Mater."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0220","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.colsurfb.2019.02.013","article-title":"Increased antibacterial activity of ZnO nanoparticles: influence of size and surface modification","volume":"177","author":"da Silva","year":"2019","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0225","first-page":"11","article-title":"ZnO nanoparticles: a promising anticancer agent","volume":"9","author":"Bisht","year":"2016","journal-title":"Nanotechnol. Sci. Appl."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e14247","article-title":"An emerging era in manufacturing of drug delivery systems: nanofabrication techniques","volume":"9","author":"Pingale","year":"2023","journal-title":"Heliyon"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0235","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1089\/adt.2025.031","article-title":"Recent trends in drug delivery systems","volume":"24","author":"Sarhan","year":"2026","journal-title":"Assay Drug Dev. Technol."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0240","doi-asserted-by":"crossref","DOI":"10.3390\/cryst12081089","article-title":"Mitochondrial dysfunction induced by zinc oxide nanoparticles","volume":"12","author":"Patr\u00f3n-Romero","year":"2022","journal-title":"Crystals"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0245","doi-asserted-by":"crossref","first-page":"25767","DOI":"10.18632\/aging.104187","article-title":"Zinc oxide nanoparticles (ZnO NPs) combined with cisplatin and gemcitabine inhibits tumor activity of NSCLC cells","volume":"12","author":"Hu","year":"2020","journal-title":"Aging"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0250","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2023.1225694","article-title":"Photodynamic therapy induced cell cycle arrest and cancer cell synchronization: review","volume":"13","author":"Moloudi","year":"2023","journal-title":"Front. Oncol."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0255","doi-asserted-by":"crossref","DOI":"10.3390\/genes8100281","article-title":"Eco-friendly formulated zinc oxide nanoparticles: induction of cell cycle arrest and apoptosis in the MCF-7 cancer cell line","volume":"8","author":"Boroumand Moghaddam","year":"2017","journal-title":"Genes"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0260","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-63258-7","article-title":"Green synthesis of zinc oxide nanoparticles using Rhus coriaria extract and their anticancer activity against triple-negative breast cancer cells","volume":"14","author":"Mongy","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0265","doi-asserted-by":"crossref","DOI":"10.3390\/molecules28020906","article-title":"Hydroponic ginseng root mediated with CMC polymer-coated zinc oxide nanoparticles for cellular apoptosis via downregulation of BCL-2 gene expression in A549 lung cancer cell line","volume":"28","author":"Jin","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0270","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.semcancer.2023.10.001","article-title":"Transcriptional regulation of EMT transcription factors in cancer","volume":"96","author":"Saitoh","year":"2023","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0275","doi-asserted-by":"crossref","DOI":"10.1016\/j.jgeb.2025.100556","article-title":"Exploring the therapeutic potential of micrornas: targeted gene regulation strategies for enhanced cancer therapy","volume":"23","author":"Pandey","year":"2025","journal-title":"J. Genet. Eng. Biotechnol."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.116165","article-title":"The regulatory mechanisms of oncomiRs in cancer","volume":"171","author":"Otmani","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0285","doi-asserted-by":"crossref","first-page":"20","DOI":"10.3892\/ijo.2021.5200","article-title":"Emerging roles and mechanisms of microRNA-222-3p in human cancer","volume":"58","author":"Wang","year":"2021","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0290","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2023.1189635","article-title":"Identification and comprehensive analysis of epithelial\u2013mesenchymal transition related target genes of miR-222-3p in breast cancer","volume":"13","author":"Fang","year":"2023","journal-title":"Front. Oncol."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0295","article-title":"KLF5-mediated transcriptional activation of miR-203a inhibits EMT and increases cisplatin sensitivity by targeting SNAI2 in tongue cancer","volume":"754","author":"Behera","year":"2026","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0305","doi-asserted-by":"crossref","DOI":"10.3892\/ijo.2021.5200","article-title":"Emerging roles and mechanisms of microRNA-222-3p in human cancer (review)","volume":"58","author":"Wang","year":"2021","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0310","doi-asserted-by":"crossref","first-page":"148","DOI":"10.14715\/cmb\/2024.70.1.20","article-title":"MiR-27a-3p exacerbates cell migration and invasion in right-sided\/left-sided colorectal cancer by targeting TGFBR2\/TCF7L2","volume":"70","author":"Bi","year":"2024","journal-title":"Cell. Mol. Biol."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0320","doi-asserted-by":"crossref","DOI":"10.3390\/md17010032","article-title":"Fucoidan structure and activity in relation to anti-cancer mechanisms","volume":"17","author":"van Weelden","year":"2019","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0340","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202305140","article-title":"Nanoparticle-based photothermal therapy for breast cancer noninvasive treatment","volume":"37","author":"Xiong","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0345","series-title":"Polysaccharide Biomaterials in Cancer Research and Therapy: From Lab to Life","first-page":"87","article-title":"Chitosan: biomedical applications and cancer therapeutic potential","author":"Aftab","year":"2026"},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0350","doi-asserted-by":"crossref","first-page":"18","DOI":"10.2174\/2666145417666230918115854","article-title":"A mini review: zinc oxide NPs as a promising cancer treatment strategy: insights into synthesis methodology and mechanisms","volume":"18","author":"Lim","year":"2025","journal-title":"Curr. Mater. Sci."},{"key":"10.1016\/j.ijbiomac.2026.154208_bb0355","first-page":"57","article-title":"Zinc oxide nanoparticles for liver cancer: advances in synthesis, mechanisms, delivery, and translational challenges","volume":"2","author":"Manzoor","year":"2026","journal-title":"J. Life Soc. Sci."}],"container-title":["International Journal of Biological Macromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813026041541?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813026041541?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,12]],"date-time":"2026-11-12T14:24:41Z","timestamp":1794493481000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0141813026041541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":66,"alternative-id":["S0141813026041541"],"URL":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2026.154208","relation":{},"ISSN":["0141-8130"],"issn-type":[{"value":"0141-8130","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fucodain loaded on zinc oxide nanoparticles derived from Turbinaria ornata suppresses skin cancer proliferation and migration via modulation of EMT-related miRNAs","name":"articletitle","label":"Article Title"},{"value":"International Journal of Biological Macromolecules","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2026.154208","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"154208"}}