{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T14:36:46Z","timestamp":1793284606646,"version":"4.5.0"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001422","name":"India Ministry of Food Processing Industries","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001422","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001409","name":"Department of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001409","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biological Macromolecules"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.ijbiomac.2026.154273","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T05:55:28Z","timestamp":1788155728000},"page":"154273","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"P2","title":["Design, heterologous expression, and functional characterization of the Salmonella-specific bacteriocin SalE1a"],"prefix":"10.1016","volume":"381","author":[{"given":"Anagha","family":"Kalathil","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kammara","family":"Rajagopal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijbiomac.2026.154273_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.hazadv.2024.100407","article-title":"Salmonella in the environment: a review on ecology, antimicrobial resistance, seafood contaminations, and human health implications","volume":"13","author":"Billah","year":"2024","journal-title":"Journal of Hazardous Materials Advances"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0010","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1080\/21553769.2015.1051243","article-title":"Salmonella: a review on pathogenesis, epidemiology and antibiotic resistance","volume":"8","author":"Eng","year":"2015","journal-title":"Front. Life Sci."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0015","article-title":"Salmonellosis: an overview of epidemiology, pathogenesis, and innovative approaches to mitigate the antimicrobial resistant infections","volume":"13","author":"Lamichhane","year":"2024","journal-title":"Antibiotics (Basel, Switzerland)"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.soh.2025.100117","article-title":"Antimicrobial resistance in Salmonella: one health perspective on global food safety challenges","volume":"4","author":"Kumar","year":"2025","journal-title":"Science in One Health"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0025","series-title":"Morbidity and Mortality Weekly Report Surveillance for Foodborne Disease Outbreaks-Centers for Disease Control and Prevention MMWR Editorial and Production Staff (Serials) MMWR Editorial Board","author":"edfield","year":"2009"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0030","series-title":"Salmonella - Current Trends and Perspectives in Detection and Control","article-title":"Salmonella disease with a health management perspective","author":"Dindar Demiray","year":"2024"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0035","doi-asserted-by":"crossref","first-page":"409","DOI":"10.5851\/kosfa.2025.e4","article-title":"Antibiotic-resistant Salmonella in animal products jeopardize human health","volume":"45","author":"Oh","year":"2025","journal-title":"Food Sci. Anim. Resour."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0040","doi-asserted-by":"crossref","DOI":"10.3390\/antibiotics11081079","article-title":"Antibiotic resistance in bacteria\u2014a review","volume":"11","author":"Urban-Chmiel","year":"2022","journal-title":"Antibiotics"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0045","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1444781","article-title":"Mechanism of antibacterial resistance, strategies and next-generation antimicrobials to contain antimicrobial resistance: a review","volume":"15","author":"Belay","year":"2024","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0050","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2018.02663","article-title":"Linoleic acids overproducing lactobacillus casei limits growth, survival, and virulence of Salmonella typhimurium and enterohaemorrhagic Escherichia coli","volume":"9","author":"Peng","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0055","unstructured":"A. Parisi, J.A. Crump, K. Glass, D. Gray, B.P. Howden, L. Furuya-Kanamori, S. Vilkins, M. Kirk, Health Outcomes from Multi-Drug-Resistant Salmonella Infections in High-Income Countries: A Systematic Review and Meta-Analysis, n.d. http:\/\/www.who.int\/medicines\/publications\/WHO-PPL-."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0060","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/nrd.2017.23","article-title":"Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance","volume":"16","author":"Dickey","year":"2017","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0065","article-title":"CRISPR-Cas9 mediated phage therapy as an alternative to antibiotics","volume":"3","author":"Balcha","year":"2023","journal-title":"Anim. Dis."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0070","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.2147\/IJN.S453566","article-title":"Recent advances in understanding the molecular mechanisms of multidrug resistance and novel approaches of CRISPR\/Cas9-based genome-editing to combat this health emergency","volume":"19","author":"Allemailem","year":"2024","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0075","doi-asserted-by":"crossref","DOI":"10.3390\/antibiotics11020200","article-title":"Progress in alternative strategies to combat antimicrobial resistance: focus on antibiotics","volume":"11","author":"Murugaiyan","year":"2022","journal-title":"Antibiotics"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0080","doi-asserted-by":"crossref","first-page":"504","DOI":"10.14202\/vetworld.2019.504-521","article-title":"A review of Salmonella enterica with particular focus on the pathogenicity and virulence factors, host specificity and adaptation and antimicrobial resistance including multidrug resistance","volume":"12","author":"Jajere","year":"2019","journal-title":"Vet. World"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0085","doi-asserted-by":"crossref","DOI":"10.3389\/fpls.2019.00437","article-title":"Colicins and Salmocins \u2013 new classes of plant-made non-antibiotic food antibacterials","volume":"10","author":"Hahn-L\u00f6bmann","year":"2019","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0090","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-22465-9","article-title":"Plant-made Salmonella bacteriocins salmocins for control of Salmonella pathovars","volume":"8","author":"Schneider","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0095","doi-asserted-by":"crossref","DOI":"10.1007\/s00203-021-02659-y","article-title":"Heterologous overexpression and preliminary antimicrobial activity test of salmocin M, a novel colicin M-like bacteriocin against Salmonella sp","volume":"204","author":"\u0141ojewska","year":"2022","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2020.104488","article-title":"Toxoplasma gondii ROP38 protein: bioinformatics analysis for vaccine design improvement against toxoplasmosis","volume":"149","author":"Nosrati","year":"2020","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0105","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-30427-z","article-title":"A novel designed membrane-active peptide for the control of foodborne Salmonella enterica serovar typhimurium","volume":"13","author":"Sengkhui","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0110","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2018.00323","article-title":"In silico approach for prediction of antifungal peptides","volume":"9","author":"Agrawal","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0115","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gks450","article-title":"AVPpred: collection and prediction of highly effective antiviral peptides","volume":"40","author":"Thakur","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0120","doi-asserted-by":"crossref","DOI":"10.1093\/bib\/bbaa153","article-title":"AntiCP 2.0: an updated model for predicting anticancer peptides","volume":"22","author":"Agrawal","year":"2021","journal-title":"Brief. Bioinform."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0125","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073957","article-title":"In silico approach for predicting toxicity of peptides and proteins","volume":"8","author":"Gupta","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0130","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0211740","article-title":"Expression, purification and characterization of the dimeric protruding domain of Macrobrachium rosenbergii nodavirus capsid protein expressed in Escherichia coli","volume":"14","author":"Chong","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.125960","article-title":"Gene expression and molecular characterization of recombinant subtilisin from Bacillus subtilis with antibacterial, antioxidant and anticancer properties","volume":"249","author":"Shettar","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0140","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.foodcont.2014.12.037","article-title":"Bacteriocin-producing Enterococcus faecalis KT2W2G isolated from mangrove forests in southern Thailand: purification, characterization and safety evaluation","volume":"54","author":"H-Kittikun","year":"2015","journal-title":"Food Control"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0145","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1111\/1751-7915.14096","article-title":"Antibacterial activity and cytotoxicity of a novel bacteriocin isolated from Pseudomonas sp. strain 166","volume":"15","author":"Wang","year":"2022","journal-title":"Microb. Biotechnol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0150","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1007\/s42770-020-00311-3","article-title":"Characterization, modes of action, and application of a novel broad-spectrum bacteriocin BM1300 produced by Lactobacillus crustorum MN047","volume":"51","author":"Lu","year":"2020","journal-title":"Braz. J. Microbiol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0155","article-title":"Antibacterial activity and action mechanism of Bacteriocin Paracin wx7 as a selective bio preservative against vancomycin-resistant Enterococcus faecalis in fresh-cut lettuce","volume":"13","author":"Zhao","year":"2024","journal-title":"Foods"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2024.107065","article-title":"Inhibitory effect of Bacillus velezensis 1273 strain cell-free supernatant against developing and preformed biofilms of Staphylococcus aureus and MRSA","volume":"197","author":"Perini","year":"2024","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.lwt.2023.115123","article-title":"Purification and antimicrobial mechanism of a novel bacteriocin produced by Lactiplantibacillus plantarum FB-2","volume":"185","author":"Li","year":"2023","journal-title":"LWT"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0170","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ejbt.2018.08.003","article-title":"Purification, characterization, mode of action, and enhanced production of Salivaricin mmaye1, a novel bacteriocin from Lactobacillus salivarius SPW1 of human gut origin","volume":"35","author":"Wayah","year":"2018","journal-title":"Electron. J. Biotechnol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcab.2023.102811","article-title":"Design, expression and characterization of lactiscin\u2014a novel broad-spectrum peptidic bacteriocin","volume":"52","author":"Rukying","year":"2023","journal-title":"Biocatal. Agric. Biotechnol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0180","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1134\/S0003683822050052","article-title":"Bacteriocins against foodborne pathogens (review)","volume":"58","author":"Banerji","year":"2022","journal-title":"Appl. Biochem. Microbiol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0185","first-page":"338","article-title":"The possibility of pore formation in lipid membranes by several molecules of amphipathic peptides","volume":"16","author":"Kondrashov","year":"2022","journal-title":"Biochem. (Mosc). Suppl. Ser. A Membr. Cell Biol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0190","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15414\/jmbfs.3733","article-title":"Classification and mechanism of bacteriocin induced cell death: a review","volume":"11","author":"Sharma","year":"2021","journal-title":"J. Microbiol. Biotechnol. Food Sci."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0195","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1134\/S0006297922110165","article-title":"Structural features, mechanisms of action, and prospects for practical application of class II bacteriocins","volume":"87","author":"Antoshina","year":"2022","journal-title":"Biochem. Mosc."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0200","doi-asserted-by":"crossref","DOI":"10.1128\/mbio.03396-21","article-title":"Bacterial competition systems share a domain required for inner membrane transport of the Bacteriocin Pyocin G from Pseudomonas aeruginosa","volume":"13","author":"Atanaskovic","year":"2022","journal-title":"MBio"},{"issue":"3","key":"10.1016\/j.ijbiomac.2026.154273_bb0205","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1093\/nar\/15.3.1281","article-title":"The codon adaptation index-a measure of directional synonymous codon usage bias, and its potential applications","volume":"15","author":"Sharp","year":"1987","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0210","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1038\/nrg2899","article-title":"Synonymous but not the same: the causes and consequences of codon bias","volume":"12","author":"Plotkin","year":"2011","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0215","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms8050639","article-title":"Bacteriocins, antimicrobial peptides from bacterial origin: overview of their biology and their impact against multidrug-resistant bacteria","volume":"8","author":"Simons","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0220","doi-asserted-by":"crossref","first-page":"2132","DOI":"10.1128\/JB.183.6.2132-2136.2001","article-title":"Identification of specific residues in colicin E1 involved in immunity protein recognition","volume":"183","author":"Lindeberg","year":"2001","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0225","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1007\/s12551-017-0314-2","article-title":"Going deep into protein secondary structure with synchrotron radiation circular dichroism spectroscopy","volume":"9","author":"Kumagai","year":"2017","journal-title":"Biophys. Rev."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0230","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21020576","article-title":"The impact of IPTG induction on plasmid stability and heterologous protein expression by Escherichia coli biofilms","volume":"21","author":"Gomes","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.biotechadv.2024.108401","article-title":"Relieving metabolic burden to improve robustness and bioproduction by industrial microorganisms","volume":"74","author":"Mao","year":"2024","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0240","doi-asserted-by":"crossref","DOI":"10.1186\/s12934-021-01680-6","article-title":"Regulating the T7 RNA polymerase expression in E. coli BL21 (DE3) to provide more host options for recombinant protein production","volume":"20","author":"Du","year":"2021","journal-title":"Microb. Cell Factories"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0245","doi-asserted-by":"crossref","DOI":"10.1186\/s12934-020-01462-6","article-title":"Protein over-expression in Escherichia coli triggers adaptation analogous to antimicrobial resistance","volume":"20","author":"James","year":"2021","journal-title":"Microb. Cell Factories"},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0250","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.tim.2011.04.004","article-title":"Structure and genetics of circular bacteriocins","volume":"19","author":"Van Belkum","year":"2011","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.135716","article-title":"Synthesis, antimicrobial activity, and mechanistic studies of enterocin DD14, a leaderless two-peptide bacteriocin","volume":"280","author":"Belguesmia","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0260","doi-asserted-by":"crossref","first-page":"2975","DOI":"10.1128\/AEM.69.5.2975-2984.2003","article-title":"Enterolysin a, a cell wall-degrading bacteriocin from Enterococcus faecalis LMG 2333","volume":"69","author":"Nilsen","year":"2003","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.ijbiomac.2026.154273_bb0265","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics14112273","article-title":"A nanocomposite with extracellular vesicles from Lactobacillus paracasei as a bioinspired nanoantibiotic targeting Staphylococcus aureus","volume":"14","author":"Naskar","year":"2022","journal-title":"Pharmaceutics"}],"container-title":["International Journal of Biological Macromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813026042194?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141813026042194?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T14:12:04Z","timestamp":1793283124000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0141813026042194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":53,"alternative-id":["S0141813026042194"],"URL":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2026.154273","relation":{},"ISSN":["0141-8130"],"issn-type":[{"value":"0141-8130","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Design, heterologous expression, and functional characterization of the Salmonella-specific bacteriocin SalE1a","name":"articletitle","label":"Article Title"},{"value":"International Journal of Biological Macromolecules","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijbiomac.2026.154273","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"154273"}}