{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T12:01:24Z","timestamp":1785326484046,"version":"3.55.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.1016\/j.ijcard.2008.12.087","type":"journal-article","created":{"date-parts":[[2009,1,27]],"date-time":"2009-01-27T10:08:30Z","timestamp":1233050910000},"page":"159-165","source":"Crossref","is-referenced-by-count":42,"title":["Heart rate variability predicts outcome in children with pulmonary arterial hypertension"],"prefix":"10.1016","volume":"142","author":[{"given":"Astrid E.","family":"Lammers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Munnery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison A.","family":"Hislop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila G.","family":"Haworth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2008.12.087_bib1","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s00408-003-1034-x","article-title":"Ventricular arrhythmias and autonomic profile in patients with primary pulmonary hypertension","volume":"181","author":"Folino","year":"2003","journal-title":"Lung"},{"key":"10.1016\/j.ijcard.2008.12.087_bib2","first-page":"19","article-title":"Clinical implications and prognostic significance of the study on the circadian variation of heart rate variability in patients with severe pulmonary hypertension","volume":"142","author":"Rosas-Peralta","year":"2006","journal-title":"Gac Med Mex"},{"key":"10.1016\/j.ijcard.2008.12.087_bib3","doi-asserted-by":"crossref","first-page":"I69","DOI":"10.1161\/01.cir.0000032886.55215.15","article-title":"Global impairment of cardiac autonomic nervous activity late after repair of tetralogy of Fallot","volume":"106","author":"Davos","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2008.12.087_bib4","first-page":"II180","article-title":"Global impairment of cardiac autonomic nervous activity late after the Fontan operation","volume":"108 Suppl 1","author":"Davos","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2008.12.087_bib5","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.jtcvs.2006.03.057","article-title":"Impaired cardiac autonomic nervous activity predicts sudden cardiac death in patients with operated and unoperated congenital cardiac disease","volume":"132","author":"Lammers","year":"2006","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ijcard.2008.12.087_bib6","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/S0140-6736(97)11144-8","article-title":"Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) Investigators","volume":"351","author":"La Rovere","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.ijcard.2008.12.087_bib7","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/0002-9149(87)90601-1","article-title":"Heart rate variability as an index of sympathovagal interaction after acute myocardial infarction","volume":"60","author":"Lombardi","year":"1987","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ijcard.2008.12.087_bib8","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S0002-9149(01)02198-1","article-title":"Heart rate turbulence-based predictors of fatal and nonfatal cardiac arrest (The Autonomic Tone and Reflexes After Myocardial Infarction substudy)","volume":"89","author":"Ghuran","year":"2002","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ijcard.2008.12.087_bib9","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1161\/01.CIR.103.16.2072","article-title":"Baroreflex sensitivity and heart rate variability in the identification of patients at risk for life-threatening arrhythmias: implications for clinical trials","volume":"103","author":"La Rovere","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2008.12.087_bib10","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/0002-9149(87)90795-8","article-title":"Decreased heart rate variability and its association with increased mortality after acute myocardial infarction","volume":"59","author":"Kleiger","year":"1987","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ijcard.2008.12.087_bib11","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1046\/j.1365-2710.2002.00404.x","article-title":"Heart rate variability\u2014a therapeutic target","volume":"27","author":"Routledge","year":"2002","journal-title":"J Clin Pharm Ther"},{"key":"10.1016\/j.ijcard.2008.12.087_bib12","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1161\/01.CIR.0000020009.30736.3F","article-title":"Neurohormonal activation and the chronic heart failure syndrome in adults with congenital heart disease","volume":"106","author":"Bolger","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2008.12.087_bib13","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1161\/CIRCULATIONAHA.104.529800","article-title":"Exercise intolerance in adult congenital heart disease: comparative severity, correlates, and prognostic implication","volume":"112","author":"Diller","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2008.12.087_bib14","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/00019501-200502000-00003","article-title":"The right ventricle in pulmonary hypertension","volume":"16","author":"Chin","year":"2005","journal-title":"Coron Artery Dis"},{"key":"10.1016\/j.ijcard.2008.12.087_bib15","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1093\/eurheartj\/ehl477","article-title":"Prognostic value of right ventricular mass, volume, and function in idiopathic pulmonary arterial hypertension","volume":"28","author":"van Wolferen","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ijcard.2008.12.087_bib16","doi-asserted-by":"crossref","first-page":"2559","DOI":"10.1161\/01.CIR.0000146803.14063.F7","article-title":"Cellular basis for therapeutic choices in heart failure","volume":"110","author":"Opie","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2008.12.087_bib17","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1253\/jcj.55.1077","article-title":"Biventricular down-regulation of beta-adrenergic receptors in right ventricular hypertrophy induced by monocrotaline","volume":"55","author":"Ishikawa","year":"1991","journal-title":"Jpn Circ J"},{"key":"10.1016\/j.ijcard.2008.12.087_bib18","first-page":"1127","article-title":"Correlation between severity of pulmonary arterial hypertension and 123I-metaiodobenzylguanidine left ventricular imaging","volume":"41","author":"Sakamaki","year":"2000","journal-title":"J Nucl Med"},{"key":"10.1016\/j.ijcard.2008.12.087_bib19","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.ancard.2006.01.005","article-title":"Heart rate variability in rats with chronic hypoxic pulmonary hypertension","volume":"55","author":"Fauchier","year":"2006","journal-title":"Ann Cardiol Angeiol (Paris)"},{"key":"10.1016\/j.ijcard.2008.12.087_bib20","doi-asserted-by":"crossref","first-page":"48S","DOI":"10.1016\/j.jacc.2004.02.010","article-title":"End points and clinical trial designs in pulmonary arterial hypertension: clinical and regulatory perspectives","volume":"43","author":"Hoeper","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2008.12.087_bib21","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1164\/ajrccm.161.2.9906015","article-title":"Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension. Comparison with cardiopulmonary exercise testing","volume":"161","author":"Miyamoto","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ijcard.2008.12.087_bib22","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1183\/09031936.00134506","article-title":"Prognostic value of blood gas analyses in patients with idiopathic pulmonary arterial hypertension","volume":"29","author":"Hoeper","year":"2007","journal-title":"Eur Respir J"},{"key":"10.1016\/j.ijcard.2008.12.087_bib23","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1056\/NEJMoa020204","article-title":"Inhaled iloprost for severe pulmonary hypertension","volume":"347","author":"Olschewski","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijcard.2008.12.087_bib24","doi-asserted-by":"crossref","first-page":"343","DOI":"10.7326\/0003-4819-115-5-343","article-title":"Survival in patients with primary pulmonary hypertension. Results from a national prospective registry","volume":"115","author":"D'Alonzo","year":"1991","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ijcard.2008.12.087_bib25","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1161\/01.CIR.89.4.1733","article-title":"Survival in primary pulmonary hypertension. Validation of a prognostic equation","volume":"89","author":"Sandoval","year":"1994","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2008.12.087_bib26","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/S0735-1097(02)02012-0","article-title":"Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival","volume":"40","author":"Sitbon","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2008.12.087_bib27","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1161\/01.CIR.0000029100.82385.58","article-title":"Survival in primary pulmonary hypertension: the impact of epoprostenol therapy","volume":"106","author":"McLaughlin","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2008.12.087_bib28","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1016\/S0735-1097(03)00121-9","article-title":"Effects of the oral endothelin-receptor antagonist bosentan on echocardiographic and doppler measures in patients with pulmonary arterial hypertension","volume":"41","author":"Galie","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2008.12.087_bib29","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.ijcard.2008.11.048","article-title":"Ethical authorship and publishing","volume":"131","author":"Coats","year":"2009","journal-title":"Int J Cardiol"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527308015040?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527308015040?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T19:38:27Z","timestamp":1684870707000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527308015040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["S0167527308015040"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2008.12.087","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2010,7]]}}}