{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T08:51:37Z","timestamp":1760863897271},"reference-count":21,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2011,5]]},"DOI":"10.1016\/j.ijcard.2010.12.099","type":"journal-article","created":{"date-parts":[[2011,4,11]],"date-time":"2011-04-11T14:26:43Z","timestamp":1302532003000},"page":"109-113","source":"Crossref","is-referenced-by-count":6,"title":["Efficacy of pharmacological treatment and genetic characterization in early diagnosed patients affected by long QT syndrome with impaired AV conduction"],"prefix":"10.1016","volume":"149","author":[{"given":"B.","family":"Sarubbi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Frisso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Romeo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Evangelista","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Cordella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"D'Alto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Santarpia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.G.","family":"Russo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Salvatore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Calabr\u00f2","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2010.12.099_bb0005","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1016\/0002-8703(95)90222-8","article-title":"Infants with long-QT syndrome and 2:1 atrioventricular block","volume":"130","author":"Trippel","year":"1995","journal-title":"Am Heart J"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0010","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1111\/j.1540-8167.1998.tb00096.x","article-title":"The long QT syndrome with impaired atrioventricular conduction: a malignant variant in infants","volume":"9","author":"Gorgels","year":"1998","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0015","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1161\/01.CIR.87.6.1866","article-title":"The long QT syndrome in children. An international study of 287 patients","volume":"87","author":"Garson","year":"1993","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0020","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1093\/eurheartj\/12.7.838","article-title":"Prolonged QT, atrioventricular block, and sudden death in the newborn: an electrophysiologic evaluation","volume":"12","author":"Saoudi","year":"1991","journal-title":"Eu Heart J"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0025","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1111\/j.1540-8159.1990.tb02077.x","article-title":"Persistent functional atrioventricular block in two patients with prolonged QT intervals: elucidation of the mechanism of the block","volume":"13","author":"Van Hare","year":"1990","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0030","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/S0735-1097(85)80317-X","article-title":"The conduction system in patients with a prolonged QT interval","volume":"6","author":"Bharati","year":"1985","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0035","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1111\/j.1540-8167.2008.01113.x","article-title":"A rare case of 2:1 AV block: long QT syndrome","volume":"19","author":"Patel","year":"2008","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0040","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/j.hrthm.2010.02.035","article-title":"Congenital long QT syndrome and 2:1 atrioventricular block: an optimistic outcome in the current era. Heart Rhythm 2010","volume":"7","author":"Aziz","year":"2010","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0045","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1016\/j.jacc.2007.06.033","article-title":"Long QT syndrome in children: not one disease anymore","volume":"50","author":"Balaji","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0050","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/0735-1097(91)90560-V","article-title":"Pseudo 2:1 atrioventricular block and T wave alternans in the long QT syndromes","volume":"18","author":"Rosenbaum","year":"1991","journal-title":"J Am Coll Cardiol"},{"issue":"54","key":"10.1016\/j.ijcard.2010.12.099_bb0055","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.jacc.2009.05.029","article-title":"Clinical implications for patients with long QT syndrome who experience a cardiac event during infancy","volume":"25","author":"Spazzolini","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0060","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.2174\/1381612053764823","article-title":"Specific therapy based on the genotype and cellular mechanism in inherited cardiac arrhythmias. long QT syndrome and Brugada syndrome","volume":"11","author":"Shimlizul","year":"2005","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0065","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/j.jacc.2003.09.049","article-title":"Long QT syndrome in neonates. Conduction disorders associated with HERG mutations and sinus bradycardia with KCNQ1 mutations","volume":"43","author":"Lupoglazoff","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0070","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1016\/S0735-1097(00)00636-7","article-title":"Homozygosity for a HERG potassium channel mutation causes a severe form of long QT syndrome: identification of an apparent founder mutation in the Finns","volume":"35","author":"Piippo","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0075","doi-asserted-by":"crossref","first-page":"e16","DOI":"10.1161\/hh1401.095087","article-title":"Homozygous SCN5A mutation in long QT syndrome with functional two-to-one atrioventricular block","volume":"89","author":"Lupoglazoff","year":"2001","journal-title":"Circ Res"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0080","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.cardiores.2004.07.007","article-title":"A novel SCN5A mutation manifests as a malignant form of long Qt syndrome with perinatal onset of tachycardia\/bradycardia","volume":"64","author":"Chang","year":"2004","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0085","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1161\/CIRCULATIONAHA.106.659086","article-title":"SCN4B-Encoded sodium channel beta4 subunit in congenital long-QT syndrome","volume":"116","author":"Medeiros-Domingo","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0090","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.cell.2004.09.011","article-title":"Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism","volume":"119","author":"Splawski","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0095","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.hrthm.2007.01.029","article-title":"Human KCNQ1 S140G mutation is associated with atrioventricular blocks","volume":"4","author":"Yang","year":"2007","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0100","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1399-0004.2009.01190.x","article-title":"A child cohort study from southern Italy enlarges the genetic spectrum of hypertrophic cardiomyopathy","volume":"76","author":"Frisso","year":"2009","journal-title":"Clin Genet"},{"key":"10.1016\/j.ijcard.2010.12.099_bb0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijcard.2010.07.030","article-title":"Ethics in the authorship and publishing of scientific articles","volume":"144","author":"Shewan","year":"2010","journal-title":"Int J Cardiol"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527310011770?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527310011770?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,3]],"date-time":"2018-12-03T17:51:14Z","timestamp":1543859474000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527310011770"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["S0167527310011770"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2010.12.099","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2011,5]]}}}