{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:08:08Z","timestamp":1761059288293,"version":"3.44.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1016\/j.ijcard.2011.12.095","type":"journal-article","created":{"date-parts":[[2012,1,16]],"date-time":"2012-01-16T06:10:45Z","timestamp":1326694245000},"page":"362-368","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["The balance of serum matrix metalloproteinase-8 and its tissue inhibitor in acute coronary syndrome and its recurrence"],"prefix":"10.1016","volume":"167","author":[{"given":"Pirkko J.","family":"Pussinen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seppo","family":"Sarna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirja","family":"Puolakkainen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans","family":"\u00d6hlin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timo","family":"Sorsa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erkki","family":"Pesonen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2011.12.095_bb0005","doi-asserted-by":"crossref","first-page":"917","DOI":"10.2174\/0929867053507270","article-title":"Matrix metalloproteinases in coronary artery disease: clinical and therapeutic implications and pathological significance","volume":"12","author":"Tayebjee","year":"2005","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0010","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1161\/01.ATV.15.8.1145","article-title":"Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm","volume":"15","author":"Freestone","year":"1995","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0015","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1111\/j.1749-6632.1994.tb17348.x","article-title":"Enhanced expression of vascular matrix metalloproteinases induced in vitro by cytokines and in regions of human atherosclerotic lesions","volume":"748","author":"Galis","year":"1995","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0020","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1586\/14779072.5.2.265","article-title":"Matrix metalloproteinases: influence on smooth muscle cells and atherosclerotic plaque stability","volume":"5","author":"Johnson","year":"2007","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0025","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1161\/01.CIR.90.4.1669","article-title":"Accumulation of activated mast cells in the shoulder region of human coronary atheroma, the predilection site of atheromatous rupture","volume":"90","author":"Kaartinen","year":"1994","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0030","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1161\/hc4101.097419","article-title":"Expression of neutrophil collagenase (matrix metalloproteinase-8) in human atheroma: a novel collagenolytic pathway suggested by transcriptional profiling","volume":"104","author":"Herman","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0035","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0167-4838(99)00279-4","article-title":"Tissue inhibitors of metalloproteinases: evolution, structure and function","volume":"1477","author":"Brew","year":"2000","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0040","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1093\/eurheartj\/ehi582","article-title":"Prognostic value of tissue inhibitor of metalloproteinase-1 for cardiovascular death among patients with cardiovascular disease: results from the AtheroGene study","volume":"27","author":"Lubos","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0045","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1002\/bjs.4993","article-title":"Matrix metalloproteinase 8 (neutrophil collagenase) in the pathogenesis of abdominal aortic aneurysm","volume":"92","author":"Wilson","year":"2005","journal-title":"Br J Surg"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0050","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1161\/CIRCULATIONAHA.105.551572","article-title":"Matrix metalloproteinase-8 and -9 are increased at the site of abdominal aortic aneurysm rupture","volume":"113","author":"Wilson","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0055","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1161\/01.CIR.0000135588.65188.14","article-title":"Unstable carotid plaques exhibit raised matrix metalloproteinase-8 activity","volume":"110","author":"Molloy","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0060","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.carpath.2007.12.012","article-title":"Increased matrix metalloproteinase-8 and -9 activity in patients with infarct rupture after myocardial infarction","volume":"18","author":"van den Borne","year":"2009","journal-title":"Cardiovasc Pathol"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0065","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.atherosclerosis.2005.08.039","article-title":"Intraplaque MMP-8 levels are increased in asymptomatic patients with carotid plaque progression on ultrasound","volume":"187","author":"Turu","year":"2006","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0070","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.atherosclerosis.2006.05.018","article-title":"Dual role of infections as risk factors for coronary heart disease","volume":"192","author":"Pesonen","year":"2007","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0075","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1161\/01.CIR.97.18.1837","article-title":"Prediction of coronary heart disease using risk factor categories","volume":"97","author":"Wilson","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0080","doi-asserted-by":"crossref","first-page":"2722","DOI":"10.1161\/ATVBAHA.107.154831","article-title":"Serum matrix metalloproteinase-8 concentrations are associated with cardiovascular outcome in men","volume":"27","author":"Tuomainen","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0085","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/sim.2929","article-title":"Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond","volume":"27","author":"Pencina","year":"2008","journal-title":"Stat Med"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0090","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1161\/01.CIR.98.4.300","article-title":"Chlamydial heat shock protein 60 localizes in human atheroma and regulates macrophage tumor necrosis factor-alpha and matrix metalloproteinase expression","volume":"98","author":"Kol","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0095","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.bbrc.2004.09.063","article-title":"TIMP-1 stimulates proliferation of human aortic smooth muscle cells and Ras effector pathways","volume":"324","author":"Akahane","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0100","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1002\/1529-0131(200106)44:6<1444::AID-ART240>3.0.CO;2-Q","article-title":"Paradoxical effects of tissue inhibitor of metalloproteinases 1 gene transfer in collagen-induced arthritis","volume":"44","author":"Apparailly","year":"2001","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0105","doi-asserted-by":"crossref","first-page":"3777","DOI":"10.1136\/hrt.69.5.377","article-title":"Risk of thrombosis in human atherosclerotic plaques: role of extracellular lipid, macrophage, and smooth muscle cell content","volume":"69","author":"Davies","year":"1993","journal-title":"Br Heart J"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0110","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1056\/NEJM199201233260406","article-title":"The pathogenesis of coronary artery disease and the acute coronary syndromes","volume":"326","author":"Fuster","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0115","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1016\/j.amjcard.2005.06.096","article-title":"Comparison of levels of matrix metalloproteinase-2 and -3 in patients with ischemic cardiomyopathy versus nonischemic cardiomyopathy","volume":"96","author":"Tziakas","year":"2005","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0120","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.atherosclerosis.2009.07.037","article-title":"High plasma levels of matrix metalloproteinase-8 in patients with unstable angina","volume":"209","author":"Momiyama","year":"2010","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0125","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1253\/circj.69.1035","article-title":"Plasma matrix metalloproteinase-8 concentrations are associated with the presence and severity of coronary artery disease","volume":"69","author":"Kato","year":"2005","journal-title":"Circ J"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0130","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1054\/jcaf.2002.129659","article-title":"Plasma matrix metalloproteinase and inhibitor profiles in patients with heart failure","volume":"8","author":"Wilson","year":"2002","journal-title":"J Card Fail"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0135","doi-asserted-by":"crossref","first-page":"e37","DOI":"10.1161\/01.STR.0000075563.45920.24","article-title":"Dysregulation of the levels of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in the early phase of cerebral ischemia","volume":"34","author":"Lorenzl","year":"2003","journal-title":"Stroke"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0140","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1067\/mhj.2001.112238","article-title":"Plasma levels of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 are increased in the coronary circulation in patients with acute coronary syndrome","volume":"141","author":"Inokubo","year":"2001","journal-title":"Am Heart J"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0145","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.4049\/jimmunol.175.4.2589","article-title":"Matrix metalloproteinase-8 deficiency promotes granulocytic allergen-induced airway inflammation","volume":"175","author":"Gueders","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0150","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1128\/IAI.00873-08","article-title":"Local and systemic responses in matrix metalloproteinase 8-deficient mice during Porphyromonas gingivalis-induced periodontitis","volume":"77","author":"Kuula","year":"2009","journal-title":"Infect Immun"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0155","first-page":"e1","article-title":"Tissue inhibitor of metalloproteinase-1 (TIMP-1) is an independent predictor of all-cause mortality, cardiac mortality, and myocardial infarction","volume":"151:1101","author":"Cavusoglu","year":"2006","journal-title":"Am Heart J"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0160","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.cca.2006.12.006","article-title":"Correlates of serum matrix metalloproteinase-8 (MMP-8) concentrations in nondiabetic subjects without cardiovascular disease","volume":"379","author":"Aquilante","year":"2007","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0165","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.ijcard.2003.05.013","article-title":"Serum profiles of matrix metalloproteinases and their tissue inhibitor in patients with acute coronary syndromes. The effects of short-term atorvastatin administration","volume":"94","author":"Tziakas","year":"2004","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.ijcard.2011.12.095_bb0170","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1161\/ATVBAHA.107.159277","article-title":"Matrix metalloproteinase-8 and tissue inhibitor of metalloproteinase-1 in serum do not reflect the analytes circulating in blood","volume":"28","author":"Tuomainen","year":"2008","journal-title":"Arterioscler Thromb Vasc Biol"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527311022765?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527311022765?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T20:33:23Z","timestamp":1759091603000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527311022765"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["S0167527311022765"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2011.12.095","relation":{},"ISSN":["0167-5273"],"issn-type":[{"type":"print","value":"0167-5273"}],"subject":[],"published":{"date-parts":[[2013,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The balance of serum matrix metalloproteinase-8 and its tissue inhibitor in acute coronary syndrome and its recurrence","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2011.12.095","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}