{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T17:44:53Z","timestamp":1769881493828,"version":"3.49.0"},"reference-count":13,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1016\/j.ijcard.2012.03.021","type":"journal-article","created":{"date-parts":[[2012,3,28]],"date-time":"2012-03-28T02:07:06Z","timestamp":1332900426000},"page":"e1-e3","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Efficacy of bosentan therapy for segmental pulmonary artery hypertension due to major aortopulmonary collateral arteries in children"],"prefix":"10.1016","volume":"161","author":[{"given":"Kenichiro","family":"Yamamura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hazumu","family":"Nagata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuyuki","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Ihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiro","family":"Hara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2012.03.021_bb0005","first-page":"375","article-title":"Report of the New England Regional Infant Cardiac Program","volume":"65","author":"Fyler","year":"1980","journal-title":"Pediatrics"},{"key":"10.1016\/j.ijcard.2012.03.021_bb0010","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1136\/heart.84.5.499","article-title":"Natural and unnatural history of pulmonary atresia","volume":"84","author":"Leonard","year":"2000","journal-title":"Heart"},{"key":"10.1016\/j.ijcard.2012.03.021_bb0015","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s11936-003-0047-3","article-title":"Management of pulmonary atresia with ventricular septal defect","volume":"5","author":"Mair","year":"2003","journal-title":"Curr Treat Options Cardiovasc Med"},{"key":"10.1016\/j.ijcard.2012.03.021_bb0020","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/0002-9149(91)90533-Q","article-title":"Pulmonary artery morphology and hemodynamics in pulmonic valve atresia with ventricular septal defect before and after repair","volume":"67","author":"Shimazaki","year":"1991","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ijcard.2012.03.021_bb0080","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.ejcts.2007.04.022","article-title":"Clinical results of staged repair with complete unifocalization for pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries","volume":"32","author":"Ishibashi","year":"2007","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.ijcard.2012.03.021_bb0030","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.ijcard.2007.08.016","article-title":"Sildenafil therapy in complex pulmonary atresia with pulmonary arterial hypertension","volume":"129","author":"Lim","year":"2008","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.ijcard.2012.03.021_bb0035","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1161\/CIRCULATIONAHA.106.630715","article-title":"Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study","volume":"114","author":"Galie","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2012.03.021_bb0040","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.ijcard.2007.04.078","article-title":"Longer-term bosentan therapy improves functional capacity in Eisenmenger syndrome: results of the BREATHE-5 open-label extension study","volume":"127","author":"Gatzoulis","year":"2008","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.ijcard.2012.03.021_bb0045","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.jacc.2005.01.066","article-title":"Effects of long-term bosentan in children with pulmonary arterial hypertension","volume":"46","author":"Rosenzweig","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2012.03.021_bb0085","article-title":"Treatment of segmental pulmonary artery hypertension in adults with congenital heart disease","author":"Schuuring","year":"2011","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.ijcard.2012.03.021_bb0055","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/S0009-9236(03)00005-5","article-title":"Pharmacokinetics, safety, and efficacy of bosentan in pediatric patients with pulmonary arterial hypertension","volume":"73","author":"Barst","year":"2003","journal-title":"Clin Pharmacol Ther"},{"key":"10.1016\/j.ijcard.2012.03.021_bb0060","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.ahj.2007.06.003","article-title":"Long-term effect of bosentan in adults versus children with pulmonary arterial hypertension associated with systemic-to-pulmonary shunt: does the beneficial effect persist?","volume":"154","author":"van Loon","year":"2007","journal-title":"Am Heart J"},{"key":"10.1016\/j.ijcard.2012.03.021_bb0065","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/j.amjcard.2010.06.064","article-title":"Long-term outcomes in children with pulmonary arterial hypertension treated with bosentan in real-world clinical settings","volume":"106","author":"Ivy","year":"2010","journal-title":"Am J Cardiol"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527312002264?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527312002264?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T20:31:36Z","timestamp":1759091496000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527312002264"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["S0167527312002264"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2012.03.021","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2012,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of bosentan therapy for segmental pulmonary artery hypertension due to major aortopulmonary collateral arteries in children","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2012.03.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}