{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:58:59Z","timestamp":1762505939959},"reference-count":66,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1016\/j.ijcard.2012.05.115","type":"journal-article","created":{"date-parts":[[2012,6,18]],"date-time":"2012-06-18T05:42:04Z","timestamp":1339998124000},"page":"1-10","source":"Crossref","is-referenced-by-count":11,"title":["Mucopolysaccharidosis type VI: A cardiologist's guide to diagnosis and treatment"],"prefix":"10.1016","volume":"167","author":[{"given":"Adam","family":"Golda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnieszka","family":"Jurecka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Violetta","family":"Opoka-Winiarska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Tylki-Szyma\u0144ska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2012.05.115_bb0005","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/BF00288275","article-title":"Chromosomal localization of ARSB, the gene for human N-acetylgalactosamine-4-sulphatase","volume":"82","author":"Litjens","year":"1989","journal-title":"Hum Genet"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0010","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1750-1172-5-5","article-title":"Mucopolysaccharidosis VI","volume":"5","author":"Valayannopoulos","year":"2010","journal-title":"Orphanet J Rare Dis"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0015","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1007\/s10545-005-0112-z","article-title":"Cumulative incidence rates of the mucopolysaccharidoses in Germany","volume":"28","author":"Baehner","year":"2005","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0020","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1007\/s10545-005-0020-2","article-title":"Mucopolysaccharidosis type VI: identification of novel mutations on the arylsulphatase B gene in South American patients","volume":"28","author":"Petry","year":"2005","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0025","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1089\/109065703322783743","article-title":"Identification of a novel mutation in the ARSB gene that is frequent among Brazilian MPSVI patients","volume":"7","author":"Petry","year":"2003","journal-title":"Genet Test"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0030","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.ymgme.2011.11.003","article-title":"Molecular analysis of mucopolysaccharidosis type VI in Poland, Belarus, Lithuania and Estonia","volume":"105","author":"Jurecka","year":"2012","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0035","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1203\/01.PDR.0000156510.96253.5A","article-title":"Joint and bone disease in mucopolysaccharidoses VI and VII: identification of new therapeutic targets and biomarkers using animal models","volume":"57","author":"Simonaro","year":"2005","journal-title":"Pediatr Res"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0040","doi-asserted-by":"crossref","first-page":"112","DOI":"10.2353\/ajpath.2008.070564","article-title":"Mechanism of glycosaminoglycan-mediated bone and joint disease: implications for the mucopolysaccharidoses and other connective tissue diseases","volume":"172","author":"Simonaro","year":"2008","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0045","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1073\/pnas.0912937107","article-title":"Involvement of the Toll-like receptor 4 pathway and use of TNF-alpha antagonists for treatment of the mucopolysaccharidoses","volume":"107","author":"Simonaro","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0050","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1038\/labinvest.3780345","article-title":"Articular chondrocytes from animals with a dermatan sulfate storage disease undergo a high rate of apoptosis and release nitric oxide and inflammatory cytokines: a possible mechanism underlying degenerative joint disease in the mucopolysaccharidoses","volume":"81","author":"Simonaro","year":"2001","journal-title":"Lab Invest"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0055","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/S0002-9440(10)64961-9","article-title":"Impaired elastogenesis in Hurler disease: dermatan sulfate accumulation linked to deficiency in elastin-binding protein and elastic fiber assembly","volume":"156","author":"Hinek","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0060","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1007\/s10545-011-9359-8","article-title":"Cardiac disease in patients with mucopolysaccharidosis: presentation, diagnosis and management","volume":"34","author":"Braunlin","year":"2011","journal-title":"J Inherit Metab Dis"},{"issue":"1","key":"10.1016\/j.ijcard.2012.05.115_bb0065","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.ijcard.2011.06.097","article-title":"Cardiovascular manifestations of mucopolysaccharidosis type VI (Maroteaux\u2013Lamy syndrome)","volume":"158","author":"Golda","year":"2012","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0070","series-title":"The metabolic and molecular basis of inherited disease","first-page":"3421","article-title":"The mucopolysaccharidoses","author":"Neufeld","year":"2001"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0075","first-page":"223","article-title":"Mucopolysaccharidoses and spinal cord compression: case report and review of the literature with implications of bone marrow transplantation","volume":"47","author":"Kachur","year":"2000","journal-title":"Neurosurgery"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0080","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.ymgme.2011.07.019","article-title":"Spinal cord compression in young children with type VI mucopolysaccharidosis","volume":"104","author":"Horovitz","year":"2011","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0085","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1542\/peds.2006-2184","article-title":"Management guidelines for mucopolysaccharidosis VI","volume":"120","author":"Giugliani","year":"2007","journal-title":"Pediatrics"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0090","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/0002-9149(81)90550-6","article-title":"Coronary artery disease in the Hurler syndrome. Qualitative and quantitative analysis of the extent of coronary narrowing at necropsy in six children","volume":"47","author":"Brosius","year":"1981","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0095","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1007\/s10545-007-0613-z","article-title":"Successful treatment of severe heart failure in an infant with Hurler syndrome","volume":"30","author":"Hirth","year":"2007","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0100","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1007\/s10545-007-0586-y","article-title":"Cardiac abnormalities in adults with the attenuated form of mucopolysaccharidosis type I","volume":"30","author":"Soliman","year":"2007","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0105","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.ymgme.2011.08.024","article-title":"Mucopolysaccharidosis Type VI (Maroteaux\u2013Lamy syndrome) with a predominantly cardiac phenotype","volume":"104","author":"Jurecka","year":"2011","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0110","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1136\/pgmj.68.798.287","article-title":"Mitral stenosis in the Maroteaux\u2013Lamy syndrome: a treatable cause of dyspnoea","volume":"68","author":"Marwick","year":"1992","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0115","doi-asserted-by":"crossref","first-page":"51","DOI":"10.2143\/AC.60.1.2005049","article-title":"Cardiovascular changes in mucopolysaccharidoses in Taiwan","volume":"60","author":"Chen","year":"2005","journal-title":"Acta Cardiol"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0120","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/clc.4960100612","article-title":"Endocardial fibroelastosis in mucopolysaccharidosis type VI","volume":"10","author":"Fong","year":"1987","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0125","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1136\/jmg.27.2.94","article-title":"Cardiovascular studies in the mucopolysaccharidoses","volume":"27","author":"Nelson","year":"1990","journal-title":"J Med Genet"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0130","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1046\/j.1460-9592.2002.01784.x","article-title":"Permanent transfemoral pacemaker implantation in a child with Maroteaux Lamy syndrome","volume":"25","author":"Dilber","year":"2002","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0135","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1161\/01.CIR.52.4.700","article-title":"Cardiac manifestations of the mucopolysaccharidoses","volume":"52","author":"Schieken","year":"1975","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0140","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1515\/CCLM.2007.061","article-title":"Fine characterization of mitral valve glycosaminoglycans and their modification with degenerative disease","volume":"45","author":"Dainese","year":"2007","journal-title":"Clin Chem Lab Med"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0145","doi-asserted-by":"crossref","first-page":"i3","DOI":"10.1093\/ejechocard\/jeq153","article-title":"Anatomy of the mitral valve: understanding the mitral valve complex in mitral regurgitation","volume":"11","author":"McCarthy","year":"2010","journal-title":"Eur J Echocardiogr"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0150","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1016\/S0140-6736(09)60994-6","article-title":"Mitral stenosis","volume":"374","author":"Chandrashekhar","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0155","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1016\/S0140-6736(09)60692-9","article-title":"Mitral regurgitation","volume":"373","author":"Enriquez-Sarano","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0160","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1136\/hrt.2007.135335","article-title":"Ischaemic mitral regurgitation: mechanisms and diagnosis","volume":"95","author":"Marwick","year":"2009","journal-title":"Heart"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0165","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1007\/s12016-008-8113-y","article-title":"Revisiting Libman\u2013Sacks endocarditis: a historical review and update","volume":"36","author":"Lee","year":"2009","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0170","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/ajmg.a.30579","article-title":"Threshold effect of urinary glycosaminoglycans and the walk test as indicators of disease progression in a survey of subjects with Mucopolysaccharidosis VI (Maroteaux\u2013Lamy syndrome)","volume":"134A","author":"Swiedler","year":"2005","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0175","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1017\/S1047951109003576","article-title":"The natural course and the impact of therapies of cardiac involvement in the mucopolysaccharidoses","volume":"19","author":"Fesslova","year":"2009","journal-title":"Cardiol Young"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0180","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.carpath.2006.11.009","article-title":"Left ventricular aneurysm in a patient with mucopolysaccharidosis type VI (Maroteaux\u2013Lamy syndrome): clinical and pathological correlation","volume":"16","author":"Oudit","year":"2007","journal-title":"Cardiovasc Pathol"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0185","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1111\/j.1399-0004.2004.00277.x","article-title":"Clinical and biochemical study of 28 patients with mucopolysaccharidosis type VI","volume":"66","author":"Azevedo","year":"2004","journal-title":"Clin Genet"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0190","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1017\/S104795110999062X","article-title":"Echocardiographic study of paediatric patients with mucopolysaccharidosis","volume":"20","author":"Leal","year":"2010","journal-title":"Cardiol Young"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0195","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1136\/adc.65.7.746","article-title":"Echocardiographic abnormalities in type IV mucopolysaccharidosis","volume":"65","author":"John","year":"1990","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0200","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1007\/BF00796996","article-title":"Severe mitral insufficiency in mucopolysaccharidosis type III-B (Sanfilippo syndrome)","volume":"14","author":"Muenzer","year":"1993","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0205","first-page":"859","article-title":"Sly disease: mucopolysaccharidosis type VII","volume":"45","author":"Nampoothiri","year":"2008","journal-title":"Indian Pediatr"},{"issue":"2","key":"10.1016\/j.ijcard.2012.05.115_bb0210","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s10545-011-9444-z","article-title":"Mucopolysaccharidosis: cardiologic features and effects of enzyme-replacement therapy in 24 children with MPS I, II and VI","volume":"36","author":"Brands","year":"2013","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0215","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.ejcts.2011.06.013","article-title":"Valve surgery in a mucopolysaccharidosis type I patient: early prosthetic valve endocarditis","volume":"41","author":"Rocha","year":"2012","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0220","doi-asserted-by":"crossref","first-page":"496","DOI":"10.7326\/0003-4819-92-4-496","article-title":"Aortic stenosis and mucopolysaccharidosis","volume":"92","author":"Wilson","year":"1980","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0225","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1161\/01.CIR.85.1.188","article-title":"Valvular heart disease in four patients with Maroteaux\u2013Lamy syndrome","volume":"85","author":"Tan","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0230","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1093\/eurheartj\/ehp285","volume":"30","author":"Habib","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0235","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0022-3476(05)80441-X","article-title":"Acute infantile cardiomyopathy as a presenting feature of mucopolysaccharidosis VI","volume":"120","author":"Hayflick","year":"1992","journal-title":"J Pediatr"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0240","first-page":"61","article-title":"Mucopolysaccharidosis type VI presenting in infancy with endocardial fibroelastosis and heart failure","volume":"4","author":"Miller","year":"1983","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0245","first-page":"317","article-title":"Mucopolysaccharidosis 6-A (Maroteaux\u2013Lamy disease): comparison of clinical and pathologico-anatomic findings in a 27-year-old patient","volume":"42","author":"Keller","year":"1987","journal-title":"Helv Paediatr Acta"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0250","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/j.ejheart.2008.08.005","volume":"10","author":"Dickstein","year":"2008","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0255","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.nmd.2008.04.010","article-title":"Lysosomal myopathies: an excessive build-up in autophagosomes is too much to handle","volume":"18","author":"Malicdan","year":"2008","journal-title":"Neuromuscul Disord"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0260","doi-asserted-by":"crossref","first-page":"2250","DOI":"10.1161\/CIRCULATIONAHA.109.192230","volume":"119","author":"McLaughlin","year":"2009","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.ijcard.2012.05.115_bb0265","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.carpath.2011.10.004","article-title":"The first cardiac transplant experience in a patient with mucopolysaccharidosis","volume":"21","author":"Grinberg","year":"2012","journal-title":"Cardiovasc Pathol"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0270","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0165-5876(01)00417-7","article-title":"Disordered breathing during sleep in patients with mucopolysaccharidoses","volume":"58","author":"Leighton","year":"2001","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0275","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/S0140-6736(08)61622-0","article-title":"Obstructive sleep apnoea and its cardiovascular consequences","volume":"373","author":"Bradley","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0280","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1097\/HJH.0b013e3282f0580f","article-title":"2007 ESH-ESC practice guidelines for the management of arterial hypertension: ESH-ESC Task Force on the Management of Arterial Hypertension","volume":"25","author":"Mancia","year":"2007","journal-title":"J Hypertens"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0285","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.ymgme.2011.09.004","article-title":"Carotid intima-media thickness is increased in patients with mucopolysaccharidoses","volume":"104","author":"Wang","year":"2011","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0290","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1093\/eurheartj\/ehl001","article-title":"Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology","volume":"27","author":"Fox","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0295","doi-asserted-by":"crossref","first-page":"2999","DOI":"10.1093\/eurheartj\/ehr236","volume":"32","author":"Hamm","year":"2011","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0300","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.1093\/eurheartj\/ehn416","article-title":"Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: the Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology","volume":"29","author":"Van de Werf","year":"2008","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0305","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1046\/j.1460-9592.1997.d01-102.x","article-title":"A fibreoptic intubation technique for children with mucopolysaccharidoses using the laryngeal mask airway","volume":"7","author":"Walker","year":"1997","journal-title":"Paediatr Anaesth"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0310","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1586\/14779072.1.4.523","article-title":"Etiology of valvular heart disease","volume":"1","author":"Boudoulas","year":"2003","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0315","doi-asserted-by":"crossref","first-page":"3584","DOI":"10.1161\/CIRCULATIONAHA.105.539775","article-title":"Rheumatic and nonrheumatic valvular heart disease: epidemiology, management, and prevention in Africa","volume":"112","author":"Essop","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0320","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.amjcard.2006.02.047","article-title":"Cardiac findings after enzyme replacement therapy for mucopolysaccharidosis type I","volume":"98","author":"Braunlin","year":"2006","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0325","doi-asserted-by":"crossref","first-page":"e37","DOI":"10.1542\/peds.2006-2156","article-title":"Enzyme replacement therapy in patients who have mucopolysaccharidosis I and are younger than 5years: results of a multinational study of recombinant human alpha-L-iduronidase (laronidase)","volume":"120","author":"Wraith","year":"2007","journal-title":"Pediatrics"},{"key":"10.1016\/j.ijcard.2012.05.115_bb0330","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.ymgme.2009.08.006","article-title":"Japan Elaprase Treatment (JET) study: idursulfase enzyme replacement therapy in adult patients with attenuated Hunter syndrome (Mucopolysaccharidosis II, MPS II)","volume":"99","author":"Okuyama","year":"2010","journal-title":"Mol Genet Metab"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527312007620?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527312007620?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T18:53:12Z","timestamp":1542912792000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527312007620"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":66,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["S0167527312007620"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2012.05.115","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]}}}