{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T22:08:43Z","timestamp":1789855723736,"version":"4.0.1"},"reference-count":42,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.ijcard.2012.06.010","type":"journal-article","created":{"date-parts":[[2012,6,22]],"date-time":"2012-06-22T22:36:49Z","timestamp":1340404609000},"page":"2250-2258","source":"Crossref","is-referenced-by-count":23,"title":["Cilostazol added to aspirin and clopidogrel reduces revascularization without increases in major adverse events in patients with drug-eluting stents: A meta-analysis of randomized controlled trials"],"prefix":"10.1016","volume":"167","author":[{"given":"Ryota","family":"Sakurai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bon-Kwon","family":"Koo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Kaneda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi N.","family":"Bonneau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryozo","family":"Nagai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2012.06.010_bb0005","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1056\/NEJMoa035071","article-title":"Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery","volume":"349","author":"Moses","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0010","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1056\/NEJMoa032441","article-title":"A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease","volume":"350","author":"Stone","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0015","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1161\/CIRCULATIONAHA.105.591206","article-title":"Randomized, double-blind, multicenter study of the Endeavor zotarolimus-eluting phosphorylcholine-encapsulated stent for treatment of native coronary artery lesions: clinical and angiographic results of the ENDEAVOR II trial","volume":"114","author":"Fajadet","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0020","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1001\/jama.294.7.819","article-title":"Sirolimus-eluting stents vs paclitaxel-eluting stents in patients with coronary artery disease: meta-analysis of randomized trials","volume":"294","author":"Kastrati","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0025","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1007\/s001250100593","article-title":"Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model","volume":"44","author":"Aoki","year":"2001","journal-title":"Diabetologia"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0030","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1097\/00004424-199509000-00004","article-title":"Pharmacologic treatment of intimal hyperplasia after metallic stent placement in the peripheral arteries. An experimental study","volume":"30","author":"Kubota","year":"1995","journal-title":"Invest Radiol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0035","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0735-1097(01)01742-9","article-title":"Coronary in-stent restenosis: current status and future strategies","volume":"39","author":"Lowe","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0040","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1161\/01.ATV.0000037100.44766.5B","article-title":"Inflammation and restenosis in the stent era","volume":"22","author":"Welt","year":"2002","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0045","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/S0741-5214(03)01029-2","article-title":"Managing PAD with multiple platelet inhibitors: the effect of combination therapy on bleeding time","volume":"38","author":"Wilhite","year":"2003","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0050","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1161\/CIRCULATIONAHA.107.188208","volume":"117","author":"King","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0055","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/j.1365-2125.2009.03402.x","article-title":"Triple antiplatelet therapy vs. dual antiplatelet therapy in patients undergoing percutaneous coronary intervention: an evidence-based approach to answering a clinical query","volume":"68","author":"Singh","year":"2009","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0060","doi-asserted-by":"crossref","first-page":"384","DOI":"10.4244\/V5I3A60","article-title":"Efficacy of cilostazol in reducing restenosis in patients undergoing contemporary stent based PCI: a meta-analysis of randomised controlled trials","volume":"5","author":"Tamhane","year":"2009","journal-title":"EuroIntervention"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0065","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1177\/0091270009338940","article-title":"Addition of cilostazol to aspirin and a thienopyridine for prevention of restenosis after coronary artery stenting: a meta-analysis","volume":"50","author":"Jennings","year":"2010","journal-title":"J Clin Pharmacol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0070","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.ijcard.2011.05.020","article-title":"A meta-analysis of randomized trials of triple versus dual antiplatelet therapy after stent-based percutaneous coronary intervention","volume":"150","author":"Takagi","year":"2011","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0075","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ijcard.2011.07.072","article-title":"Benefit, rather than safety, of cilostazol for long-term mortality in patients undergoing percutaneous coronary intervention: a meta-analysis of randomized trials","volume":"153","author":"Takagi","year":"2011","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0197-2456(95)00134-4","article-title":"Assessing the quality of reports of randomized clinical trials: is blinding necessary?","volume":"17","author":"Jadad","year":"1996","journal-title":"Control Clin Trials"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0085","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1002\/sim.1761","article-title":"What to add to nothing? Use and avoidance of continuity corrections in meta-analysis of sparse data","volume":"23","author":"Sweeting","year":"2004","journal-title":"Stat Med"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0090","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/sim.2528","article-title":"Much ado about nothing: a comparison of the performance of meta-analytical methods with rare events","volume":"26","author":"Bradburn","year":"2007","journal-title":"Stat Med"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0095","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat Med"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0100","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.2307\/2533446","article-title":"Operating characteristics of a rank correlation test for publication bias","volume":"50","author":"Begg","year":"1994","journal-title":"Biometrics"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0105","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0110","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/S0895-4356(00)00242-0","article-title":"Publication and related bias in meta-analysis: power of statistical tests and prevalence in the literature","volume":"53","author":"Sterne","year":"2000","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0115","doi-asserted-by":"crossref","first-page":"W65","DOI":"10.7326\/0003-4819-151-4-200908180-00136","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration","volume":"151","author":"Liberati","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0120","doi-asserted-by":"crossref","first-page":"2826","DOI":"10.1161\/CIRCULATIONAHA.104.530097","article-title":"Coronary stent restenosis in patients treated with cilostazol","volume":"112","author":"Douglas","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0125","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.ahj.2009.01.006","article-title":"Cilostazol in addition to aspirin and clopidogrel improves long-term outcomes after percutaneous coronary intervention in patients with acute coronary syndromes: a randomized, controlled study","volume":"157","author":"Han","year":"2009","journal-title":"Am Heart J"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0130","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1253\/circj.71.1685","article-title":"Effect of cilostazol on in-stent neointimal hyperplasia after coronary artery stenting: a quantitative coronary angiography and volumetric intravascular ultrasound study","volume":"71","author":"Min","year":"2007","journal-title":"Circ J"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0135","author":"Long-DES-II Study investigators"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0140","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1253\/circj.71.1867","article-title":"Cilostazol could ameliorate platelet responsiveness to clopidogrel in patients undergoing primary percutaneous coronary intervention","volume":"71","author":"Kim","year":"2007","journal-title":"Circ J"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0145","first-page":"368","article-title":"Effects of long-term triple anti-platelet therapy with low-dose cilostazol after drug-eluting stent implantation","volume":"74","author":"Kim","year":"2008","journal-title":"Korean J Med"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0150","doi-asserted-by":"crossref","first-page":"21","DOI":"10.4070\/kcj.2009.39.1.21","article-title":"Clinical effects of additional cilostazol administration after drug-eluting stent insertion","volume":"39","author":"Kum","year":"2009","journal-title":"Korean Circ J"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0155","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.amjcard.2009.08.667","article-title":"Comparison of triple antiplatelet therapy and dual antiplatelet therapy in patients at high risk of restenosis after drug-eluting stent implantation (from the DECLARE-DIABETES and -LONG Trials)","volume":"105","author":"Lee","year":"2010","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0160","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jacc.2010.08.631","volume":"57","author":"Suh","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0165","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1016\/j.jacc.2010.10.035","volume":"57","author":"Lee","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0170","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1007\/s00380-010-0093-1","article-title":"Cilostazol reduces the progression of carotid intima-media thickness without increasing the risk of bleeding in patients with acute coronary syndrome during a 2-year follow-up","volume":"26","author":"Ahn","year":"2011","journal-title":"Heart Vessels"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0175","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.amjcard.2007.05.032","article-title":"Comparison of triple versus dual antiplatelet therapy after drug-eluting stent implantation (from the DECLARE-Long trial)","volume":"100","author":"Lee","year":"2007","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0180","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.jacc.2007.11.049","volume":"51","author":"Lee","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0185","doi-asserted-by":"crossref","first-page":"C1715","DOI":"10.1152\/ajpcell.00143.2002","article-title":"Modulation of the erythropoietin-induced proliferative pathway by cAMP in vascular smooth muscle cells","volume":"283","author":"Ito","year":"2002","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0190","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1161\/01.HYP.35.1.237","article-title":"Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21","volume":"35","author":"Hayashi","year":"2000","journal-title":"Hypertension"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0195","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1016\/j.jacc.2004.06.066","article-title":"Cilostazol inhibits leukocyte integrin Mac-1, leading to a potential reduction in restenosis after coronary stent implantation","volume":"44","author":"Inoue","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0200","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1001\/jama.282.11.1054","article-title":"The hazards of scoring the quality of clinical trials for meta-analysis","volume":"282","author":"Juni","year":"1999","journal-title":"JAMA"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0210","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1161\/CIRCULATIONAHA.106.666396","article-title":"Sirolimus-eluting stent versus paclitaxel-eluting stent for patients with long coronary artery disease","volume":"114","author":"Kim","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2012.06.010_bb0215","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/1745-6215-11-87","volume":"11","author":"Lee","year":"2010","journal-title":"Trials"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527312007851?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527312007851?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T16:21:56Z","timestamp":1542903716000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527312007851"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":42,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["S0167527312007851"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2012.06.010","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]}}}