{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T18:03:31Z","timestamp":1794333811151,"version":"4.9.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,12,26]],"date-time":"2013-12-26T00:00:00Z","timestamp":1388016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1016\/j.ijcard.2013.12.051","type":"journal-article","created":{"date-parts":[[2014,1,4]],"date-time":"2014-01-04T05:01:11Z","timestamp":1388811671000},"page":"96-102","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":38,"title":["Trajectories of the Framingham general cardiovascular risk profile in midlife and poor motor function later in life: The Whitehall II study"],"prefix":"10.1016","volume":"172","author":[{"given":"Alexis","family":"Elbaz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin J.","family":"Shipley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermann","family":"Nabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric J.","family":"Brunner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mika","family":"Kivimaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archana","family":"Singh-Manoux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl. 2","key":"10.1016\/j.ijcard.2013.12.051_bb0005","doi-asserted-by":"crossref","first-page":"S319","DOI":"10.1111\/j.1532-5415.2010.02983.x","article-title":"The aging mind: vascular health in normal cognitive aging","volume":"58","author":"Warsch","year":"2010","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0010","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1161\/STR.0b013e3182299496","article-title":"Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"42","author":"Gorelick","year":"2011","journal-title":"Stroke"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0015","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.maturitas.2011.04.008","article-title":"Physical performance characteristics related to disability in older persons: a systematic review","volume":"69","author":"den Ouden","year":"2011","journal-title":"Maturitas"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0020","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1001\/jama.2010.1923","article-title":"Gait speed and survival in older adults","volume":"305","author":"Studenski","year":"2011","journal-title":"JAMA"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0025","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1097\/HJH.0b013e328338bbec","article-title":"Hypertension and lower walking speed in the elderly: the Three-City study","volume":"28","author":"Dumurgier","year":"2009","journal-title":"J Hypertens"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0030","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.gaitpost.2011.07.014","article-title":"Gait pattern alterations in older adults associated with type 2 diabetes in the absence of peripheral neuropathy\u2014results from the Baltimore Longitudinal Study of Aging","volume":"34","author":"Ko","year":"2011","journal-title":"Gait Posture"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0035","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.1161\/01.STR.0000181752.16915.5c","article-title":"Common carotid artery intima\u2013media thickness, carotid plaques, and walking speed","volume":"36","author":"Elbaz","year":"2005","journal-title":"Stroke"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0040","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1136\/hrt.2009.183350","article-title":"Walking speed and subclinical atherosclerosis in healthy older adults: the Whitehall II study","volume":"96","author":"Hamer","year":"2010","journal-title":"Heart"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0045","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1161\/HYPERTENSIONAHA.110.168864","article-title":"Arterial stiffness, physical function, and functional limitation: the Whitehall II study","volume":"57","author":"Brunner","year":"2011","journal-title":"Hypertension"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0050","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1161\/CIRCULATIONAHA.109.849166","article-title":"Cardiovascular risk prediction: basic concepts, current status, and future directions","volume":"121","author":"Lloyd-Jones","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0055","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S1474-4422(06)70537-3","article-title":"Risk score for the prediction of dementia risk in 20years among middle aged people: a longitudinal, population-based study","volume":"5","author":"Kivipelto","year":"2006","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0060","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1161\/01.STR.0000103141.82869.77","article-title":"Framingham stroke risk profile and lowered cognitive performance","volume":"35","author":"Elias","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0065","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.1093\/eurheartj\/ehr133","article-title":"Predictive utility of the Framingham general cardiovascular disease risk profile for cognitive function: evidence from the Whitehall II study","volume":"32","author":"Kaffashian","year":"2011","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0070","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1161\/CIRCULATIONAHA.107.699579","article-title":"General cardiovascular risk profile for use in primary care: the Framingham Heart Study","volume":"117","author":"D'Agostino","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0075","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1016\/0140-6736(91)93068-K","article-title":"Health inequalities among British civil servants: the Whitehall II study","volume":"337","author":"Marmot","year":"1991","journal-title":"Lancet"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0080","first-page":"8","article-title":"Validity study of the Western psychological services finger-tapping test","volume":"2","author":"Dilks","year":"2006","journal-title":"Am J Psychol Res"},{"issue":"Suppl. 1","key":"10.1016\/j.ijcard.2013.12.051_bb0185","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.2337\/diacare.26.2007.S5","article-title":"Report of the expert committee on the diagnosis and classification of diabetes mellitus","volume":"26","author":"Expert committee on the diagnosis and classification of diabetes mellitus","year":"2003","journal-title":"Diabetes Care"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0090","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1161\/01.CIR.90.1.583","article-title":"Myocardial infarction and coronary deaths in the World Health Organization MONICA Project. Registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four continents","volume":"90","author":"Tunstall-Pedoe","year":"1994","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0095","series-title":"AH 4 group test of general intelligence","author":"Heim","year":"1970"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0100","doi-asserted-by":"crossref","first-page":"e27899","DOI":"10.1371\/journal.pone.0027899","article-title":"Age and gender differences in physical capability levels from mid-life onwards: the harmonisation and meta-analysis of data from eight UK cohort studies","volume":"6","author":"Cooper","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0105","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1093\/gerona\/glp078","article-title":"Social inequality in walking speed in early old age in the Whitehall II study","volume":"64","author":"Brunner","year":"2009","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0110","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1093\/gerona\/glp077","article-title":"A cross-sectional and longitudinal study of the relation between walking speed and cognitive function in community-dwelling elderly people","volume":"64","author":"Soumar\u00e9","year":"2009","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0115","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1159\/000081043","article-title":"Association between physical and cognitive function in healthy elderly: the health, aging and body composition study","volume":"24","author":"Rosano","year":"2005","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0120","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1111\/j.1532-5415.2010.03282.x","article-title":"High blood pressure accelerates gait slowing in well-functioning older adults over 18-years of follow-up","volume":"59","author":"Rosano","year":"2011","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0125","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0002-9343(02)01269-X","article-title":"Homocysteine levels and decline in physical function: MacArthur Studies of Successful Aging","volume":"113","author":"Kado","year":"2002","journal-title":"Am J Med"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0130","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1212\/01.wnl.0000237325.16502.08","article-title":"Homocysteine and motor function in the elderly","volume":"67","author":"Soumar\u00e9","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0135","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1093\/gerona\/62.4.434","article-title":"Relationship of homocysteine levels to quadriceps strength, gait speed, and late-life disability in older adults","volume":"62","author":"Kuo","year":"2007","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0140","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1111\/j.1532-5415.2007.01608.x","article-title":"High-density lipoprotein cholesterol and objective measures of lower extremity performance in older nondisabled persons: the InChianti study","volume":"56","author":"Volpato","year":"2008","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0145","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1111\/j.1532-5415.2008.01719.x","article-title":"Incident physical disability in people with lower extremity peripheral arterial disease: the role of cardiovascular disease","volume":"56","author":"Brach","year":"2008","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0150","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/j.1532-5415.2005.00584.x","article-title":"Risk and predictors of motor-performance decline in a normally functioning population-based sample of elderly subjects: the Italian Longitudinal Study on Aging","volume":"54","author":"Inzitari","year":"2006","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0155","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1002\/ana.21674","article-title":"White matter lesions volume and motor performances in the elderly","volume":"65","author":"Soumar\u00e9","year":"2009","journal-title":"Ann Neurol"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0160","doi-asserted-by":"crossref","first-page":"2086","DOI":"10.1161\/STROKEAHA.110.610360","article-title":"Impact of white matter lesions on physical functioning and fall risk in older people: a systematic review","volume":"42","author":"Zheng","year":"2011","journal-title":"Stroke"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0165","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1056\/NEJMoa032782","article-title":"Vascular risk factors and diabetic neuropathy","volume":"352","author":"Tesfaye","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0170","doi-asserted-by":"crossref","first-page":"b4460","DOI":"10.1136\/bmj.b4460","article-title":"Slow walking speed and cardiovascular death in well functioning older adults: prospective cohort study","volume":"339","author":"Dumurgier","year":"2009","journal-title":"BMJ"},{"issue":"3","key":"10.1016\/j.ijcard.2013.12.051_bb0190","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1007\/s11357-012-9387-9","article-title":"Association of walking speed in late midlife with overall and cause-specific mortality: results from the Whitehall II cohort study","volume":"35","author":"Elbaz","year":"2012","journal-title":"Age"},{"key":"10.1016\/j.ijcard.2013.12.051_bb0180","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1093\/ije\/dyp153","article-title":"Non-response to baseline, non-response to follow-up and mortality in the Whitehall II cohort","volume":"38","author":"Ferrie","year":"2009","journal-title":"Int J Epidemiol"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527313022614?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527313022614?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T13:51:52Z","timestamp":1647870712000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527313022614"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["S0167527313022614"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2013.12.051","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2014,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Trajectories of the Framingham general cardiovascular risk profile in midlife and poor motor function later in life: The Whitehall II study","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2013.12.051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ireland Ltd.","name":"copyright","label":"Copyright"}]}}