{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T08:35:42Z","timestamp":1784277342434,"version":"3.55.0"},"reference-count":101,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","internationaljournalofcardiology.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1016\/j.ijcard.2014.05.004","type":"journal-article","created":{"date-parts":[[2014,5,9]],"date-time":"2014-05-09T16:56:00Z","timestamp":1399654560000},"page":"21-29","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":53,"title":["Cognitive impairment and cardiovascular disease: So near, so far"],"prefix":"10.1016","volume":"175","author":[{"given":"Eugenio","family":"Picano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa Maria","family":"Bruno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Franco","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ubaldo","family":"Bonuccelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2014.05.004_bb0130","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1016\/S0140-6736(05)67889-0","article-title":"Global prevalence of dementia: a delphi consensus study","volume":"366","author":"Ferri","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0135","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1038\/475S2a","article-title":"Dementia: a problem for our age","volume":"475","author":"Abbott","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0140","doi-asserted-by":"crossref","first-page":"359","DOI":"10.3233\/JAD-2011-091402","article-title":"Epidemiological neuropathology: the MRC cognitive function and aging study experience","volume":"25","author":"Wharton","year":"2011","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0145","doi-asserted-by":"crossref","first-page":"367516","DOI":"10.1155\/2012\/367516","article-title":"Cardiovascular risk factors promote brain hypoperfusion leading to cognitive decline and dementia","volume":"2012","author":"de la Torre","year":"2012","journal-title":"Cardiovasc Psychiatry Neurol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0150","doi-asserted-by":"crossref","first-page":"450","DOI":"10.7326\/0003-4819-139-5_Part_2-200309021-00014","article-title":"Healthy aging and dementia: findings from the Nun study","volume":"139","author":"Snowdon","year":"2003","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0155","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.nic.2011.11.006","article-title":"Reserve, brain changes, and decline","volume":"22","author":"Staff","year":"2012","journal-title":"Neuroimaging Clin N Am"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0160","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1016\/j.neuropsychologia.2009.03.004","article-title":"Cognitive reserve","volume":"47","author":"Stern","year":"2009","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0165","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1001\/archneurol.2007.27","article-title":"Brain volume decline in aging: evidence for a relation between socioeconomic status, preclinical Alzheimer disease, and reserve","volume":"65","author":"Fotenos","year":"2008","journal-title":"Arch Neurol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0170","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/0021-9681(56)90146-1","article-title":"Human cerebral blood flow and oxygen consumption as related to aging","volume":"3","author":"Kety","year":"1956","journal-title":"J Chronic Dis"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0175","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1476-7120-10-20","article-title":"The impact of aging and atherosclerotic risk factors on transthoracic coronary flow reserve in subjects with normal coronary angiography","volume":"10","author":"Galderisi","year":"2012","journal-title":"Cardiovasc Ultrasound"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0180","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1161\/01.CIR.91.7.1981","article-title":"Aging and endothelial function in normotensive subjects and patients with essential hypertension","volume":"91","author":"Taddei","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0185","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s00401-010-0718-6","article-title":"The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia","volume":"120","author":"Iadecola","year":"2010","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0190","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1161\/STROKEAHA.112.653618","article-title":"Toward the neurovascular unit. A journey in clinical translation: 2012 Thomas Willis lecture","volume":"44","author":"Del Zoppo","year":"2013","journal-title":"Stroke"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0195","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/978-0-387-71764-7_23","article-title":"Normal cardiac output, oxygen delivery and oxygen extraction","volume":"599","author":"Wolff","year":"2007","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0200","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0079-6123(06)53007-9","article-title":"The selfish brain: competition for energy resources","volume":"153","author":"Fehm","year":"2006","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0205","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1161\/hc0202.102119","article-title":"Prognostic role of myocardial blood flow impairment in idiopathic left ventricular dysfunction","volume":"105","author":"Neglia","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0210","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1056\/NEJMra061889","article-title":"Coronary microvascular dysfunction","volume":"356","author":"Camici","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0215","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1161\/01.STR.0000014421.15948.67","article-title":"Alzheimer disease as a vascular disorder: nosological evidence","volume":"33","author":"de la Torre","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0220","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1212\/WNL.0b013e31828ab370","article-title":"Predicting cognitive decline: a dementia risk score vs. the Framingham vascular risk scores","volume":"80","author":"Kaffashian","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0225","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/0140-6736(90)93028-N","article-title":"Effect of central cholinergic stimulation on regional cerebral blood flow in Alzheimer disease","volume":"335","author":"Geaney","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0230","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.bbr.2009.12.047","article-title":"The cerebrovascular role of the cholinergic neural system in Alzheimer's disease","volume":"221","author":"Van Beek","year":"2011","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0235","doi-asserted-by":"crossref","first-page":"189","DOI":"10.2174\/157488711796575577","article-title":"Neuroinflammation and ageing: current theories and an overview of the data","volume":"6","author":"Pizza","year":"2011","journal-title":"Rev Recent Clin Trials"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0240","doi-asserted-by":"crossref","first-page":"R148","DOI":"10.1186\/gb-2008-9-10-r148","article-title":"Variations in the transcriptome of Alzheimer's disease reveal molecular networks involved in cardiovascular diseases","volume":"9","author":"Ray","year":"2008","journal-title":"Genome Biol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0245","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.18632\/aging.100413","article-title":"Molecular links between cellular senescence, longevity and age-related diseases \u2014 a systems biology perspective","volume":"3","author":"Tacutu","year":"2011","journal-title":"Aging"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0250","series-title":"The cerebral circulation","author":"Cipolla","year":"2009"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0255","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1007\/s11886-012-0304-8","article-title":"The dementia of cardiac disease","volume":"14","author":"Muqtadar","year":"2012","journal-title":"Curr Cardiol Rep"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0260","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/j.neurobiolaging.2012.10.010","article-title":"Baroreflex function is reduced in Alzheimer's disease: a candidate biomarker?","volume":"34","author":"den Abeelen AS","year":"2013","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0265","doi-asserted-by":"crossref","DOI":"10.3233\/JAD-132507","article-title":"Ultrasound subclinical markers in assessing vascular changes in cognitive decline and dementia","author":"Demarin","year":"2014","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0270","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.neurobiolaging.2012.09.011","article-title":"The capillary dysfunction hypothesis of Alzheimer's disease","volume":"34","author":"\u00d8stergaard","year":"2013","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0275","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1007\/s00234-008-0374-x","article-title":"The venous manifestations of pulse wave encephalopathy: Windkessel dysfunction in normal aging and senile dementia","volume":"50","author":"Bateman","year":"2008","journal-title":"Neuroradiology"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0280","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/nrn3114","article-title":"Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders","volume":"12","author":"Zlokovic","year":"2011","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0285","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.rmed.2012.03.013","article-title":"Cognitive dysfunction in patients with chronic obstructive pulmonary disease\u2014a systematic review","volume":"106","author":"Schou","year":"2012","journal-title":"Respir Med"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0290","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1080\/13803390490515450","article-title":"Compromised arterial oxygen saturation in elderly asthma sufferers results in selective cognitive impairment","volume":"27","author":"Moss","year":"2005","journal-title":"J Clin Exp Neuropsychol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0295","doi-asserted-by":"crossref","first-page":"549","DOI":"10.2174\/1567205011310050011","article-title":"Chronic obstructive pulmonary disease and asthma and the risk of mild cognitive impairment and dementia: a population based Caide study","volume":"10","author":"Rusanen","year":"2013","journal-title":"Curr Alzheimer Res"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0300","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1378\/chest.11-2214","article-title":"Neurocognitive impairment in obstructive sleep apnea","volume":"141","author":"Lal","year":"2012","journal-title":"Chest"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0305","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1161\/CIRCULATIONAHA.107.189420","volume":"118","author":"Somers","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0310","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.amjmed.2005.01.030","article-title":"Correlates of cognitive impairment among patients with heart failure: results of a multicenter survey","volume":"118","author":"Zuccala","year":"2005","journal-title":"Am J Med"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0315","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1046\/j.1445-5994.2001.00067.x","article-title":"The mind of a failing heart: a systematic review of the association between congestive heart failure and cognitive functioning","volume":"31","author":"Almeida","year":"2001","journal-title":"Intern Med J"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0320","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1001\/archinte.166.9.1003","article-title":"Heart failure and risk of dementia and Alzheimer disease: a population-based cohort study","volume":"166","author":"Qiu","year":"2006","journal-title":"Arch Int Med"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0325","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1093\/eurheartj\/ehs053","article-title":"Cognitive impairment and risk of cardiovascular events and mortality","volume":"33","author":"O'Donnell","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0330","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1093\/eurheartj\/ehr467","article-title":"Cognitive and brain changes associated with ischaemic heart disease and heart failure","volume":"33","author":"Almeida","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0335","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1007\/s00246-010-9730-9","article-title":"Central nervous system changes in pediatric heart failure: a volumetric study","volume":"31","author":"Menteer","year":"2010","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0340","first-page":"135","article-title":"Heart disease as a risk factor for dementia","volume":"5","author":"Justin","year":"2013","journal-title":"Clin Epidemiol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0345","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1111\/j.1532-5415.2011.03508.x","article-title":"Atrial fibrillation and risk of dementia: a prospective cohort study","volume":"59","author":"Dublin","year":"2011","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0350","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.jacc.2013.03.073","article-title":"Subtle post-procedural cognitive dysfunction after atrial fibrillation ablation","volume":"62","author":"Medi","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0355","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1161\/STR.0b013e3182299496","article-title":"Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association\/american stroke association","volume":"42","author":"Gorelick","year":"2011","journal-title":"Stroke"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0360","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1212\/01.wnl.0000172914.08967.dc","article-title":"Aggregation of vascular risk factors and risk of incident Alzheimer disease","volume":"65","author":"Luchsinger","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0365","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1152\/japplphysiol.90549.2008","article-title":"Effects of central arterial aging on the structure and function of the peripheral vasculature: implications for end-organ damage","volume":"105","author":"Mitchell","year":"2008","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0370","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1097\/HJH.0b013e32834c7bd9","article-title":"Pulse wave encephalopathy","volume":"30","author":"O'Rourke","year":"2012","journal-title":"J Hypertens"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0375","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1161\/01.STR.0000181771.82518.1c","article-title":"Relationship between arterial stiffness and cognitive function in elderly subjects with complaints of memory loss","volume":"36","author":"Hanon","year":"2005","journal-title":"Stroke"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0380","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1161\/HYPERTENSIONAHA.107.093674","article-title":"Pulse pressure and pulse wave velocity are related to cognitive decline in the Baltimore longitudinal study of aging","volume":"51","author":"Waldstein","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0385","doi-asserted-by":"crossref","first-page":"3398","DOI":"10.1093\/brain\/awr253","article-title":"Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene\/Environment Susceptibility\u2014Reykjavik study","volume":"134","author":"Mitchell","year":"2011","journal-title":"Brain"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0390","doi-asserted-by":"crossref","first-page":"621","DOI":"10.3233\/JAD-2009-1079","article-title":"Altered cerebral hemodynamics in early Alzheimer disease: a pilot study using transcranial doppler","volume":"17","author":"Claassen","year":"2009","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0395","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jns.2010.08.056","article-title":"Relationship between orthostatic hypotension and cognitive impairment in the elderly","volume":"299","author":"Mehrabian","year":"2010","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0400","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000255459","article-title":"Orthostatic hypotension and cognitive function: the atherosclerosis risk in communities study","volume":"34","author":"Rose","year":"2010","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0405","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.jalz.2010.08.228","article-title":"Intracranial atherosclerosis as a contributing factor to Alzheimer's disease dementia","volume":"7","author":"Roher","year":"2011","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0410","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0140-6736(96)09328-2","article-title":"Atherosclerosis, apolipoprotein e, and prevalence of dementia and Alzheimer's disease in the Rotterdam study","volume":"349","author":"Hofman","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0415","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1365-2990.2010.01139.x","article-title":"Review: cerebral microvascular pathology in ageing and neurodegeneration","volume":"37","author":"Brown","year":"2011","journal-title":"Neuropathol Appl Neurobiol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0420","first-page":"1267","article-title":"Dementia resulting from dural arteriovenous fistulas: the pathologic findings of venous hypertensive encephalopathy","volume":"19","author":"Hurst","year":"1998","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0425","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1002\/ana.22276","article-title":"More severe white matter changes in the elderly with jugular venous reflux","volume":"69","author":"Chung","year":"2011","journal-title":"Ann Neurol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0430","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1186\/1741-7015-11-167","article-title":"Chronic cerebrospinal venous insufficiency is not associated with cognitive impairment in multiple sclerosis","volume":"11","author":"Benedict","year":"2013","journal-title":"BMC Med"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0435","doi-asserted-by":"crossref","first-page":"341","DOI":"10.2500\/aap.2011.32.3459","article-title":"Improved activity and mental function related to proper antiasthmatic treatment in elderly patients with Alzheimer's disease","volume":"32","author":"Bozek","year":"2011","journal-title":"Allergy Asthma Proc"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0440","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1111\/j.1532-5415.2012.04171.x","article-title":"Effect of coexisting chronic obstructive pulmonary disease and cognitive impairment on health outcomes in older adults","volume":"60","author":"Chang","year":"2012","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0445","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.4081\/ni.2011.e15","article-title":"Obstructive sleep apnea","volume":"3","author":"Ho","year":"2011","journal-title":"Neurol Int"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0450","doi-asserted-by":"crossref","first-page":"305","DOI":"10.5664\/jcsm.27538","article-title":"Sustained use of CPAP slows deterioration of cognition, sleep, and mood in patients with Alzheimer's disease and obstructive sleep apnea: a preliminary study","volume":"5","author":"Cooke","year":"2009","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0455","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1093\/eurjhf\/hfs033","volume":"14","author":"McMurray","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0460","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1111\/j.1600-0404.1995.tb07001.x","article-title":"Neuropsychological function in patients with end-stage heart failure before and after cardiac transplantation","volume":"91","author":"Bornstein","year":"1995","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0465","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jns.2004.11.003","article-title":"Coronary artery bypass grafting (CABG) and cognitive decline: a review","volume":"229\u2013230","author":"Royter","year":"2005","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0470","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1097\/HJH.0b013e3283603f53","article-title":"Antihypertensive classes, cognitive decline and incidence of dementia: a network meta-analysis","volume":"31","author":"Levi Marpillat","year":"2013","journal-title":"J Hypertens"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0475","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1001\/archinternmed.2011.1391","article-title":"Effect of antihypertensive therapy on cognitive function in early executive cognitive impairment: a double-blind randomized clinical trial","volume":"172","author":"Hajjar","year":"2012","journal-title":"Arch Int Med"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0480","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1001\/jamaneurol.2013.217","article-title":"Blood pressure and progression of brain atrophy: the SMART-MR Study","volume":"70","author":"Jochemsen","year":"2013","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0485","first-page":"CD003804","article-title":"Effect of the treatment of Type II diabetes mellitus on the development of cognitive impairment and dementia","author":"Areosa","year":"2002","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0490","first-page":"CD003160","article-title":"Statins for the prevention of dementia","author":"McGuinness","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0495","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1111\/j.1468-1331.2006.01512.x","article-title":"EFNS guidelines on the diagnosis and management of orthostatic hypotension","volume":"13","author":"Lahrmann","year":"2006","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0500","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.surg.2011.06.031","article-title":"Carotid endarterectomy protects elderly patients from cognitive decline: a prospective study","volume":"151","author":"Baracchini","year":"2012","journal-title":"Surgery"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0505","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.arr.2011.12.009","article-title":"Cerebrovascular hemodynamics in Alzheimer's disease and vascular dementia: a meta-analysis of transcranial Doppler studies","volume":"11","author":"Sabayan","year":"2012","journal-title":"Ageing Res Rev"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0005","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1192\/bjp.bp.105.016188","article-title":"Cerebral emboli and depressive symptoms in dementia","volume":"189","author":"Purandare","year":"2006","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0010","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1259\/bjr\/90498392","article-title":"Paradoxical embolisation and cerebral white matter lesions in dementia","volume":"81","author":"Purandare","year":"2008","journal-title":"Br J Radiol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0015","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1161\/CIRCOUTCOMES.109.884171","article-title":"Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE) Investigators. Cognitive function and anticoagulation control in patients with atrial fibrillation","volume":"3","author":"Flaker","year":"2010","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0020","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1111\/j.1468-1331.2006.01318.x","article-title":"MRI and SPECT studies of dural arteriovenous fistulas presenting as pure progressive dementia with leukoencephalopathy: a cause of treatable dementia","volume":"13","author":"Waragai","year":"2006","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0025","doi-asserted-by":"crossref","first-page":"229","DOI":"10.2176\/nmc.51.229","article-title":"Treatment of dural arteriovenous fistula presenting as typical symptoms of hydrocephalus caused by venous congestion: case report","volume":"51","author":"Nakahara","year":"2011","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0030","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1161\/CIR.0b013e3181dbece1","volume":"121","author":"Brook","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0035","series-title":"Environmental threats to healthy aging","author":"Stein","year":"2008"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0040","doi-asserted-by":"crossref","first-page":"f2360","DOI":"10.1136\/bmj.f2360","article-title":"Cancer risk in 680000 people exposed to computed tomography scans in childhood or adolescence: data linkage study of 11 million Australians","volume":"346","author":"Mathews","year":"2013","journal-title":"BMJ"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0045","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1289\/ehp.1204982","article-title":"Systematic review and meta-analysis of circulatory disease from exposure to low-level ionizing radiation and estimates of potential population mortality risks","volume":"120","author":"Little","year":"2012","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0050","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1186\/1471-2407-12-157","article-title":"Cancer and non-cancer brain and eye effects of chronic low-dose ionizing radiation exposure","volume":"12","author":"Picano","year":"2012","journal-title":"BMC Cancer"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0055","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1152\/physrev.00036.2012","article-title":"Environment and brain plasticity: towards an endogenous pharmacotherapy","volume":"94","author":"Sale","year":"2014","journal-title":"Physiol Rev"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0060","doi-asserted-by":"crossref","first-page":"S16","DOI":"10.1038\/475S16a","article-title":"Prevention: activity is the best medicine","volume":"475","author":"Deweerdt","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0065","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/j.neuro.2007.01.012","article-title":"Can endocrine disruptors influence neuroplasticity in the aging brain?","volume":"28","author":"Weiss","year":"2007","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0070","doi-asserted-by":"crossref","first-page":"e44","DOI":"10.1016\/j.jacc.2012.07.013","volume":"60","author":"Fihn","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0075","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1001\/jamainternmed.2013.1215","article-title":"Exercise in Alzheimer disease: comment on \u201cEffects of the Finnish Alzheimer Disease Exercise Trial (FINALEX): a randomized controlled trial\u201d","volume":"173","author":"Clarfield","year":"2013","journal-title":"JAMA Int Med"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0080","first-page":"CD006489","article-title":"Exercise programs for people with dementia","volume":"12","author":"Forbes","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0085","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.arr.2012.07.003","article-title":"Cognitive interventions in healthy older adults and people with mild cognitive impairment: a systematic review","volume":"12","author":"Reijnders","year":"2013","journal-title":"Ageing Res Rev"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0090","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1017\/S1041610209990196","article-title":"Research on treating neuropsychiatric symptoms of advanced dementia with non-pharmacological strategies, 1998\u20132008: a systematic literature review","volume":"21","author":"Kverno","year":"2009","journal-title":"Int Psychogeriatr"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0095","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1001\/jamainternmed.2013.359","article-title":"Effects of the Finnish Alzheimer Disease Exercise Trial (FINALEX): a randomized controlled trial","volume":"173","author":"Pitk\u00e4l\u00e4","year":"2013","journal-title":"JAMA Int Med"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0100","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1749-6632.2012.06482.x","article-title":"The links between complex coronary disease, cerebrovascular disease, and degenerative brain disease","volume":"1254","author":"Kovacic","year":"2012","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0105","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1161\/CIRCULATIONAHA.110.970301","article-title":"Cardiac index as a correlate of brain volume: separating the wheat of normal aging from the chaff of vascular cognitive disorders","volume":"122","author":"Wright","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0110","first-page":"27","article-title":"Cardiogenic dementia","volume":"1","author":"Anonymous","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0115","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1093\/eurheartj\/ehs128","article-title":"Cognition matters in cardiovascular disease and heart failure","volume":"33","author":"Angermann","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0120","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1093\/eurheartj\/eht544","article-title":"Endothelial nitric oxide: protector of a healthy mind","volume":"35","author":"Katusic","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ijcard.2014.05.004_bb0125","doi-asserted-by":"crossref","first-page":"H620","DOI":"10.1152\/ajpheart.00624.2012","article-title":"Endothelium-dependent control of cerebrovascular functions through age: exercise for healthy cerebrovascular aging","volume":"305","author":"Bolduc","year":"2013","journal-title":"Am J Physiol Heart Circ Physiol"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527314009723?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527314009723?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,19]],"date-time":"2020-08-19T07:06:54Z","timestamp":1597820814000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527314009723"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":101,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S0167527314009723"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2014.05.004","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cognitive impairment and cardiovascular disease: So near, so far","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2014.05.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}