{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T19:45:00Z","timestamp":1776714300372,"version":"3.51.2"},"reference-count":54,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","internationaljournalofcardiology.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.ijcard.2014.06.044","type":"journal-article","created":{"date-parts":[[2014,7,2]],"date-time":"2014-07-02T10:18:45Z","timestamp":1404296325000},"page":"62-73","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"title":["Excess ROS induced by AAPH causes myocardial hypertrophy in the developing chick embryo"],"prefix":"10.1016","volume":"176","author":[{"given":"Yan","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Yu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhao-long","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Di","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manli","family":"Chuai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth Ka Ho","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Kurihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuesong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2014.06.044_bb0005","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.cardiores.2006.03.016","article-title":"NADPH oxidase-dependent redox signalling in cardiac hypertrophy, remodelling and failure","volume":"71","author":"Murdoch","year":"2006","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0010","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1006\/jmcc.2002.1526","article-title":"Role of oxidative stress in myocardial hypertrophy and failure","volume":"34","author":"Sawyer","year":"2002","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0015","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1172\/JCI200524408","article-title":"Oxygen, oxidative stress, hypoxia, and heart failure","volume":"115","author":"Giordano","year":"2005","journal-title":"J Clin Invest"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0020","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biocel.2006.07.001","article-title":"Free radicals and antioxidants in normal physiological functions and human disease","volume":"39","author":"Valko","year":"2007","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0025","first-page":"293","article-title":"The role of oxidative stress in physiological and pathological processes in the thyroid gland; possible involvement in pineal\u2013thyroid interactions","volume":"24","author":"Karbownik","year":"2003","journal-title":"Neuro Endocrinol Lett"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0030","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/978-1-4615-1321-6_27","article-title":"Oxidative stress and functional deficit in diabetic cardiomyopathy","volume":"498","author":"Singal","year":"2001","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0035","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1096\/fasebj.14.1.111","article-title":"An embryoprotective role for glucose-6-phosphate dehydrogenase in developmental oxidative stress and chemical teratogenesis","volume":"14","author":"Nicol","year":"2000","journal-title":"FASEB J"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0040","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1093\/toxsci\/kfn263","article-title":"Oxidative stress in developmental origins of disease: teratogenesis, neurodevelopmental deficits, and cancer","volume":"108","author":"Wells","year":"2009","journal-title":"Toxicol Sci"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0045","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/bdrc.20098","article-title":"Effects of oxidative stress on embryonic development","volume":"81","author":"Dennery","year":"2007","journal-title":"Birth Defects Res C Embryo Today"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0050","doi-asserted-by":"crossref","first-page":"H820","DOI":"10.1152\/ajpheart.00827.2010","article-title":"Differential contribution of mitochondria, NADPH oxidases, and glycolysis to region-specific oxidant stress in the anoxic-reoxygenated embryonic heart","volume":"300","author":"Raddatz","year":"2011","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0055","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3109\/10715769809065798","article-title":"Studies of the cellular distribution of superoxide dismutases in adult and fetal rat tissues","volume":"28","author":"Mackler","year":"1998","journal-title":"Free Radic Res"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0060","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0742-8413(97)00062-5","article-title":"Antioxidant enzymatic activity in embryos and placenta of rats chronically exposed to hypoxia and hyperoxia","volume":"117","author":"Mover","year":"1997","journal-title":"Comp Biochem Physiol C Pharmacol Toxicol Endocrinol"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0065","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1159\/000087586","article-title":"Oxidative stress in the newborn \u2014 a 30-year perspective","volume":"88","author":"Saugstad","year":"2005","journal-title":"Biol Neonate"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0070","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.reprotox.2007.04.005","article-title":"Embryonic cardiac arrhythmia and generation of reactive oxygen species: common teratogenic mechanism for IKr blocking drugs","volume":"24","author":"Danielsson","year":"2007","journal-title":"Reprod Toxicol"},{"issue":"Pt 1","key":"10.1016\/j.ijcard.2014.06.044_bb0075","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1111\/j.1469-7793.1999.243ad.x","article-title":"Hyperoxia and local organ blood flow in the developing chick embryo","volume":"515","author":"van Golde","year":"1999","journal-title":"J Physiol"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0080","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1203\/00006450-200207000-00010","article-title":"Oxidative stress in preterm neonates at birth and on the seventh day of life","volume":"52","author":"Buonocore","year":"2002","journal-title":"Pediatr Res"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0085","first-page":"243","article-title":"Oxygen radical injury in the immature isolated rabbit heart","volume":"16","author":"Parrish","year":"1991","journal-title":"J Dev Physiol"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0090","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J Biol Chem"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0095","doi-asserted-by":"crossref","first-page":"3496","DOI":"10.1002\/dvdy.21373","article-title":"The developing embryonic cardiac outflow tract is highly sensitive to oxidant stress","volume":"236","author":"Fisher","year":"2007","journal-title":"Dev Dyn"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0100","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.ydbio.2003.11.017","article-title":"Role of myocardial hypoxia in the remodeling of the embryonic avian cardiac outflow tract","volume":"267","author":"Sugishita","year":"2004","journal-title":"Dev Biol"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0105","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/dvdy.10360","article-title":"Epicardium is required for the full rate of myocyte proliferation and levels of expression of myocyte mitogenic factors FGF2 and its receptor, FGFR-1, but not for transmural myocardial patterning in the embryonic chick heart","volume":"228","author":"Pennisi","year":"2003","journal-title":"Dev Dyn"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0110","first-page":"262","article-title":"Principle of growth in thickness of the heart ventricular wall in the chick embryo","volume":"19","author":"Rychterova","year":"1971","journal-title":"Folia Morphol (Praha)"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0115","first-page":"131","article-title":"Development of proliferation structure of the ventricular heart wall in the chick embryo between the 6th and 14th day of embryogenesis","volume":"26","author":"Rychterova","year":"1978","journal-title":"Folia Morphol (Praha)"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0120","first-page":"R518","article-title":"Hyperplasia and hypertrophy of chicken cardiac myocytes during posthatching development","volume":"273","author":"Li","year":"1997","journal-title":"Am J Physiol"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0125","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1136\/hrt.2005.076885","article-title":"Increased periconceptual maternal glycated haemoglobin in diabetic mothers reduces fetal long axis cardiac function","volume":"92","author":"Gardiner","year":"2006","journal-title":"Heart"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0130","first-page":"15","article-title":"The impacts of maternal gestational diabetes mellitus (GDM) on fetal hearts","volume":"25","author":"Chu","year":"2012","journal-title":"Biomed Environ Sci"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0135","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1177\/1933719112466298","article-title":"Cardiomyopathy and diastolic dysfunction in the embryo and neonate of a type 1 diabetic mouse model","volume":"20","author":"Corrigan","year":"2013","journal-title":"Reprod Sci"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0140","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1253\/circj.69.617","article-title":"Increased reactive oxygen species and anti-oxidative response in mitochondrial cardiomyopathy","volume":"69","author":"Ishikawa","year":"2005","journal-title":"Circ J"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0145","doi-asserted-by":"crossref","first-page":"e57732","DOI":"10.1371\/journal.pone.0057732","article-title":"A new oxidative stress model, 2,2-azobis(2-amidinopropane) dihydrochloride induces cardiovascular damages in chicken embryo","volume":"8","author":"He","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0150","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/j.1440-169X.2008.01040.x","article-title":"Method for electroporation for the early chick embryo","volume":"50","author":"Hatakeyama","year":"2008","journal-title":"Dev Growth Differ"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0155","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/aja.1001950404","article-title":"A series of normal stages in the development of the chick embryo. 1951","volume":"195","author":"Hamburger","year":"1992","journal-title":"Dev Dyn"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0160","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1161\/01.HYP.0000215207.54689.31","article-title":"Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload","volume":"47","author":"Izumiya","year":"2006","journal-title":"Hypertension"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0165","doi-asserted-by":"crossref","first-page":"E899","DOI":"10.1073\/pnas.1108559108","article-title":"Cardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overload","volume":"108","author":"Shimano","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0170","doi-asserted-by":"crossref","first-page":"3521","DOI":"10.1242\/dev.023416","article-title":"PDGF signalling controls the migration of mesoderm cells during chick gastrulation by regulating N-cadherin expression","volume":"135","author":"Yang","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0175","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1242\/dev.015321","article-title":"Wnt3a-mediated chemorepulsion controls movement patterns of cardiac progenitors and requires RhoA function","volume":"135","author":"Yue","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0180","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/375787a0","article-title":"Expression of a Delta homologue in prospective neurons in the chick","volume":"375","author":"Henrique","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0185","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.cub.2006.12.026","article-title":"PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration","volume":"17","author":"Leslie","year":"2007","journal-title":"Curr Biol"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0190","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1749-8104-3-28","article-title":"Persistent expression of BMP-4 in embryonic chick adrenal cortical cells and its role in chromaffin cell development","volume":"3","author":"Huber","year":"2008","journal-title":"Neural Dev"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0195","doi-asserted-by":"crossref","first-page":"46129","DOI":"10.1074\/jbc.M407057200","article-title":"Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in mice","volume":"279","author":"Beller","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0200","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1161\/CIRCULATIONAHA.108.823799","article-title":"Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction","volume":"119","author":"Doser","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0205","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.1242\/jcs.01158","article-title":"Muscle-specific RING finger-2 (MURF-2) is important for microtubule, intermediate filament and sarcomeric M-line maintenance in striated muscle development","volume":"117","author":"McElhinny","year":"2004","journal-title":"J Cell Sci"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0210","doi-asserted-by":"crossref","first-page":"e33190","DOI":"10.1371\/journal.pone.0033190","article-title":"Anti-stress effects of carnosine on restraint-evoked immunocompromise in mice through spleen lymphocyte number maintenance","volume":"7","author":"Li","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0215","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/0012-1606(91)90343-2","article-title":"Identification and characterization of a ventricular-specific avian myosin heavy chain, VMHC1: expression in differentiating cardiac and skeletal muscle","volume":"148","author":"Bisaha","year":"1991","journal-title":"Dev Biol"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0275","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1074\/jbc.275.3.1944","article-title":"Identification and genomic cloning of CMHC1. A unique myosin heavy chain expressed exclusively in the developing chicken heart","volume":"275","author":"Croissant","year":"2000","journal-title":"J Biol Chem."},{"key":"10.1016\/j.ijcard.2014.06.044_bb0225","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1161\/HYPERTENSIONAHA.109.141127","article-title":"Wnt signaling is critical for maladaptive cardiac hypertrophy and accelerates myocardial remodeling","volume":"55","author":"Malekar","year":"2010","journal-title":"Hypertension"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0230","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.amjmed.2003.10.012","article-title":"Hypertrophic cardiomyopathy: an important global disease","volume":"116","author":"Maron","year":"2004","journal-title":"Am J Med"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0235","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/j.1540-8167.2007.00965.x","article-title":"Genetic basis of hypertrophic cardiomyopathy: from bench to the clinics","volume":"19","author":"Alcalai","year":"2008","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0240","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1056\/NEJM199005313222203","article-title":"Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study","volume":"322","author":"Levy","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0245","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1161\/CIRCULATIONAHA.109.878579","article-title":"Contemporary insights and strategies for risk stratification and prevention of sudden death in hypertrophic cardiomyopathy","volume":"121","author":"Maron","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0250","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1136\/hrt.2005.068270","article-title":"Oxidative stress and redox signalling in cardiac hypertrophy and heart failure","volume":"93","author":"Seddon","year":"2007","journal-title":"Heart"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0255","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1007\/s10059-011-0276-3","article-title":"Regulation of reactive oxygen species generation in cell signaling","volume":"32","author":"Bae","year":"2011","journal-title":"Mol Cells"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0260","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1161\/01.RES.30.6.690","article-title":"Myosin synthesis and degradation during development of cardiac hypertrophy in the rabbit","volume":"30","author":"Morkin","year":"1972","journal-title":"Circ Res"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0265","doi-asserted-by":"crossref","first-page":"3140","DOI":"10.1161\/CIRCULATIONAHA.105.550806","article-title":"Increased alpha2 subunit-associated AMPK activity and PRKAG2 cardiomyopathy","volume":"112","author":"Ahmad","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2014.06.044_bb0270","doi-asserted-by":"crossref","first-page":"H1753","DOI":"10.1152\/ajpheart.518.2008","article-title":"Cardiac glycogen accumulation after dexamethasone is regulated by AMPK","volume":"295","author":"Puthanveetil","year":"2008","journal-title":"Am J Physiol Heart Circ Physiol"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527314011115?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527314011115?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T17:45:46Z","timestamp":1716918346000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527314011115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":54,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S0167527314011115"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2014.06.044","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Excess ROS induced by AAPH causes myocardial hypertrophy in the developing chick embryo","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2014.06.044","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}