{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T05:40:33Z","timestamp":1778910033861,"version":"3.51.4"},"reference-count":11,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","internationaljournalofcardiology.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1016\/j.ijcard.2015.03.375","type":"journal-article","created":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T11:35:55Z","timestamp":1427888155000},"page":"421-425","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Endogenous vascular endothelial growth factor produces tonic facilitation of cardiac vagal baroreflex via fetal liver kinase-1 in medulla oblongata"],"prefix":"10.1016","volume":"187","author":[{"given":"Ching-Yi","family":"Tsai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chia-Hao","family":"Su","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steve","family":"Leu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice Y.W.","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie Y.H.","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel H.H.","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2015.03.375_bb0005","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1749-6632.2000.tb06320.x","article-title":"Molecular basis of angiogenesis. Role of VEGF and VE-cadherin","volume":"902","author":"Carmeliet","year":"2000","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.ijcard.2015.03.375_bb0010","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1038\/376062a0","article-title":"Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice","volume":"376","author":"Shalaby","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.ijcard.2015.03.375_bb0015","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.ijcard.2014.10.019","article-title":"VEGF tonically sustains myocardial performance via fetal liver kinase-1 in the heart","volume":"177","author":"Tsai","year":"2014","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2015.03.375_bb0020","doi-asserted-by":"crossref","first-page":"15809","DOI":"10.1073\/pnas.95.26.15809","article-title":"Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors","volume":"95","author":"Marti","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ijcard.2015.03.375_bb0025","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.neuroimage.2013.05.124","article-title":"Visualizing oxidative stress-induced depression of cardiac vagal baroreflex by MRI\/DTI in a mouse neurogenic hypertension model","volume":"82","author":"Tsai","year":"2013","journal-title":"NeuroImage"},{"key":"10.1016\/j.ijcard.2015.03.375_bb0030","doi-asserted-by":"crossref","first-page":"R904","DOI":"10.1152\/ajpregu.00488.2006","article-title":"Optimal frequency ranges for extracting information on cardiovascular autonomic control from the blood pressure and pulse interval spectrograms in mice","volume":"292","author":"Baudrie","year":"2007","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.ijcard.2015.03.375_bb0035","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0304-3940(83)90482-2","article-title":"Brainstem projections of aortic baroreceptor afferent fibers in the rat","volume":"36","author":"Ciriello","year":"1983","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ijcard.2015.03.375_bb0040","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1097\/00005344-199606000-00011","article-title":"Effects of vascular endothelial growth factor on hemodynamics and cardiac performance","volume":"27","author":"Yang","year":"1996","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"10.1016\/j.ijcard.2015.03.375_bb0045","doi-asserted-by":"crossref","first-page":"11410","DOI":"10.1074\/jbc.M111085200","article-title":"Paracrine and autocrine functions of neuronal vascular endothelial growth factor (VEGF) in the central nervous system","volume":"277","author":"Ogunshola","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijcard.2015.03.375_bb0050","doi-asserted-by":"crossref","first-page":"a006577","DOI":"10.1101\/cshperspect.a006577","article-title":"Anti-VEGF therapies in the clinic","volume":"2","author":"Meadows","year":"2012","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"10.1016\/j.ijcard.2015.03.375_bb0055","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1093\/annonc\/mdp206","article-title":"Hypertension as a surrogate marker for the activity of anti-VEGF agents","volume":"20","author":"Mir","year":"2009","journal-title":"Ann. Oncol."}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527315006336?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527315006336?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,24]],"date-time":"2018-09-24T01:27:25Z","timestamp":1537752445000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527315006336"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":11,"alternative-id":["S0167527315006336"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2015.03.375","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2015,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Endogenous vascular endothelial growth factor produces tonic facilitation of cardiac vagal baroreflex via fetal liver kinase-1 in medulla oblongata","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2015.03.375","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}