{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T14:16:11Z","timestamp":1789395371508,"version":"build-2803163510"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.ijcard.2016.02.137","type":"journal-article","created":{"date-parts":[[2016,3,9]],"date-time":"2016-03-09T02:45:43Z","timestamp":1457491543000},"page":"336-345","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"special_numbering":"C","title":["Cost-effectiveness of strain-targeted cardioprotection for prevention of chemotherapy-induced cardiotoxicity"],"prefix":"10.1016","volume":"212","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8125-929X","authenticated-orcid":false,"given":"Mark T.","family":"Nolan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Plana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paaladinesh","family":"Thavendiranathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslee","family":"Shaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Si","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas H.","family":"Marwick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.ijcard.2016.02.137_bb0005","first-page":"877","article-title":"Low to moderate dose anthracycline-based chemotherapy is associated with early noninvasive imaging evidence of subclinical cardiovascular disease","volume":"6","author":"Drafts","year":"2013","journal-title":"J. Am. Coll. Cardiol. CV Img"},{"issue":"11","key":"10.1016\/j.ijcard.2016.02.137_bb0010","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1002\/cncr.11407","article-title":"Congestive heart failure in patients treated with doxorubicin: a retrospective analysis of three trials","volume":"97","author":"Swain","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.ijcard.2016.02.137_bb0015","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1056\/NEJM200004133421502","article-title":"Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy","volume":"342","author":"Felker","year":"2000","journal-title":"N. Engl. J. Med."},{"issue":"5","key":"10.1016\/j.ijcard.2016.02.137_bb0020","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1200\/JCO.2002.20.5.1215","article-title":"Cardiac dysfunction in the trastuzumab clinical trials experience","volume":"20","author":"Seidman","year":"2002","journal-title":"J. Clin. Oncol."},{"issue":"25 Pt A","key":"10.1016\/j.ijcard.2016.02.137_bb0025","doi-asserted-by":"crossref","first-page":"2751","DOI":"10.1016\/j.jacc.2014.01.073","article-title":"Use of myocardial strain imaging by echocardiography for the early detection of cardiotoxicity in patients during and after cancer chemotherapy: a systematic review","volume":"63","author":"Thavendiranathan","year":"2014","journal-title":"J. Am. Coll. Cardiol."},{"issue":"23","key":"10.1016\/j.ijcard.2016.02.137_bb0030","doi-asserted-by":"crossref","first-page":"2355","DOI":"10.1016\/j.jacc.2013.02.072","volume":"61","author":"Bosch","year":"2013","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2016.02.137_bb0040","series-title":"Current Procedural Terminology.","year":"2014"},{"key":"10.1016\/j.ijcard.2016.02.137_bb0045","unstructured":"Walmart Retail Prescription Program Drug List. Updated May 2014. http:\/\/i.walmartimages.com\/i\/if\/hmp\/fusion\/customer_list.pdf."},{"key":"10.1016\/j.ijcard.2016.02.137_bb0050","unstructured":"World Health Organization. CHOosing Interventions that are Cost Effective (WHO-CHOICE): cost-effectiveness thresholds. Available at: http:\/\/www.who.int\/choice\/costs\/CER_thresholds\/en\/index.html. (Accessed March 26, 2013)"},{"key":"10.1016\/j.ijcard.2016.02.137_bb0055","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.jval.2012.04.012","article-title":"Model transparency and validation: a report of the ISPOR-SMDM modelling good research practices task force-7","volume":"15","author":"Eddy","year":"2012","journal-title":"Value Health"},{"issue":"5","key":"10.1016\/j.ijcard.2016.02.137_bb0060","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.echo.2013.02.008","article-title":"Independent and incremental value of deformation indices for prediction of trastuzumab-induced cardiotoxicity","volume":"26","author":"Negishi","year":"2013","journal-title":"J. Am. Soc. Echocardiogr."},{"issue":"23","key":"10.1016\/j.ijcard.2016.02.137_bb0065","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1001\/jama.1995.03530230025025","article-title":"Cost-effectiveness of warfarin and aspirin for prophylaxis of stroke in patients with nonvalvular atrial fibrillation","volume":"274","author":"Gage","year":"1995","journal-title":"JAMA"},{"issue":"10","key":"10.1016\/j.ijcard.2016.02.137_bb0070","first-page":"1063","article-title":"Expert consensus for multimodality imaging evaluation of adult patients during and after cancer therapy: a report from the American Society of Echocardiography and the European Association of Cardiovascular imaging","volume":"15","author":"Plana","year":"2014","journal-title":"Cardiovasc Img"},{"issue":"3","key":"10.1016\/j.ijcard.2016.02.137_bb0075","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.jacc.2009.03.095","article-title":"Anthracycline-induced cardiomyopathy: clinical relevance and response to pharmacologic therapy","volume":"55","author":"Cardinale","year":"2010","journal-title":"J. Am. Coll. Cardiol."},{"issue":"2","key":"10.1016\/j.ijcard.2016.02.137_bb0080","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1600-0609.1999.tb01734.x","article-title":"Natriuretic peptides as markers of cardiotoxicity during doxorubicin treatment for non-Hodgkin's lymphoma","volume":"62","author":"Nousiainen","year":"1999","journal-title":"Eur. J. Haematol."},{"issue":"23","key":"10.1016\/j.ijcard.2016.02.137_bb0085","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.1161\/CIRCULATIONAHA.106.635144","article-title":"Prevention of high-dose chemotherapy-induced cardiotoxicity in high-risk patients by angiotensin-converting enzyme inhibition","volume":"114","author":"Cardinale","year":"2006","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.ijcard.2016.02.137_bb0090","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1161\/CIRCIMAGING.112.973321","article-title":"Assessment of echocardiography and biomarkers for the extended prediction of cardiotoxicity in patients treated with anthracyclines, taxanes, and trastuzumab","volume":"5","author":"Sawaya","year":"2012","journal-title":"Circ. Cardiovasc. Imaging"},{"issue":"3","key":"10.1016\/j.ijcard.2016.02.137_bb0095","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1161\/HHF.0b013e318291329a","article-title":"Forecasting the impact of heart failure in the United States: a policy statement from the American Heart Association","volume":"6","author":"Heidenreich","year":"2013","journal-title":"Circ. Heart Fail."},{"issue":"9","key":"10.1016\/j.ijcard.2016.02.137_bb0100","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/j.amjcard.2011.01.006","article-title":"Early detection and prediction of cardiotoxicity in chemotherapy-treated patients","volume":"107","author":"Sawaya","year":"2011","journal-title":"Am. J. Cardiol."},{"issue":"22","key":"10.1016\/j.ijcard.2016.02.137_bb0105","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1016\/j.jacc.2010.11.063","volume":"57","author":"Fallah-Rad","year":"2011","journal-title":"J. Am. Coll. Cardiol."},{"issue":"11","key":"10.1016\/j.ijcard.2016.02.137_bb0110","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1016\/j.jacc.2006.07.052","article-title":"Protective effects of carvedilol against anthracycline-induced cardiomyopathy","volume":"48","author":"Kalay","year":"2006","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2016.02.137_bb0115","doi-asserted-by":"crossref","first-page":"2900","DOI":"10.1016\/j.ejca.2013.04.030","article-title":"Role of cardioprotective therapy for prevention of cardiotoxicity with chemotherapy: a systematic review and meta-analysis","volume":"49","author":"Kalam","year":"2013","journal-title":"Eur. J. Cancer"},{"issue":"3","key":"10.1016\/j.ijcard.2016.02.137_bb0120","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1161\/CIRCHEARTFAILURE.112.000055","article-title":"Cardioprotective effect of beta-adrenoceptor blockade in patients with breast cancer undergoing chemotherapy: follow-up study of heart failure","volume":"6","author":"Seicean","year":"2013","journal-title":"Circ. Heart Fail."},{"key":"10.1016\/j.ijcard.2016.02.137_bb0125","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S1388-9842(01)00123-4","article-title":"Economics of chronic heart failure","volume":"3","author":"Berrry","year":"2001","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcard.2016.02.137_bb0130","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1053\/euhj.2000.2532","article-title":"Reduced costs with bisoprolol treatment for heart failure: an economic analysis of the second Cardiac Insufficiency Bisoprolol Study (CIBIS-II)","volume":"22","author":"McMurray","year":"2001","journal-title":"Eur. Heart J."},{"issue":"2","key":"10.1016\/j.ijcard.2016.02.137_bb0135","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s00392-007-0586-9","article-title":"Cost-effectiveness of cardiac resynchronization therapy in combination with an implantable cardioverter defibrillator (CRT-D) for the treatment of chronic heart failure from a German health care system perspective","volume":"97","author":"Aidelsburger","year":"2008","journal-title":"Clin. Res. Cardiol."},{"issue":"10","key":"10.1016\/j.ijcard.2016.02.137_bb0140","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1001\/archinte.1994.00420100129016","article-title":"Costs and effectiveness of angiotensin converting enzyme inhibition in patients with congestive heart failure","volume":"154","author":"Paul","year":"1994","journal-title":"Arch. Intern. Med."},{"issue":"15","key":"10.1016\/j.ijcard.2016.02.137_bb0160","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1056\/NEJM199304153281506","article-title":"Trends in Medicare payments in the last year of life","volume":"328","author":"Lubitz","year":"1993","journal-title":"N. Engl. J. Med."},{"issue":"7","key":"10.1016\/j.ijcard.2016.02.137_bb0165","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1002\/(SICI)1099-1557(199912)8:7<529::AID-PDS460>3.0.CO;2-J","article-title":"A cost-analysis of suspected adverse drug reactions in a hospital emergency ward","volume":"8","author":"Ayani","year":"1999","journal-title":"Pharmacoepidemiol. Drug Saf."},{"issue":"12","key":"10.1016\/j.ijcard.2016.02.137_bb0170","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1007\/s002280000260","article-title":"Analysis of the direct cost of adverse drug reactions in hospitalised patients","volume":"56","author":"Bordet","year":"2001","journal-title":"Eur. J. Clin. Pharmacol."},{"issue":"1","key":"10.1016\/j.ijcard.2016.02.137_bb0175","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1524-4733.2008.00425.x","article-title":"Utility estimates for decision-analytic modeling in chronic heart failure\u2013health states based on New York Heart Association classes and number of rehospitalizations","volume":"12","author":"Gohler","year":"2009","journal-title":"Value Health"},{"issue":"2","key":"10.1016\/j.ijcard.2016.02.137_bb0180","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1177\/0272989X9301300202","article-title":"The Beaver Dam Health Outcomes Study: initial catalog of health-state quality factors","volume":"13","author":"Fryback","year":"1993","journal-title":"Med. Decis. Making"},{"issue":"12","key":"10.1016\/j.ijcard.2016.02.137_bb0185","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1016\/S0895-7061(98)00180-0","article-title":"The cost and cardioprotective effects of enalapril in hypertensive patients with left ventricular dysfunction","volume":"11","author":"Cook","year":"1998","journal-title":"Am. J. Hypertens."},{"key":"10.1016\/j.ijcard.2016.02.137_bb0190","doi-asserted-by":"crossref","first-page":"540","DOI":"10.7326\/0003-4819-149-8-200810210-00006","article-title":"Cost-effectiveness of nurse-led disease management for heart failure in an ethnically diverse urban community","volume":"149","author":"Hebert","year":"2008","journal-title":"Ann. Intern. Med."},{"issue":"9","key":"10.1016\/j.ijcard.2016.02.137_bb0195","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/S1053-2498(01)00298-4","article-title":"Preferences for quality of life or survival expressed by patients with heart failure","volume":"20","author":"Lewis","year":"2001","journal-title":"J. Heart Lung Transplant."},{"issue":"4","key":"10.1016\/j.ijcard.2016.02.137_bb0200","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1002\/hep.21605","article-title":"Cost-effectiveness analysis of variceal ligation vs. beta-blockers for primary prevention of variceal bleeding","volume":"45","author":"Imperiale","year":"2007","journal-title":"Hepatology"},{"issue":"2","key":"10.1016\/j.ijcard.2016.02.137_bb0205","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1586\/erp.11.8","article-title":"Cost-effectiveness of angiotensin-converting enzyme inhibitors in nondiabetic advanced renal disease","volume":"11","author":"Adarkwah","year":"2011","journal-title":"Expert Rev. Pharmacoecon. Outcomes Res."}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527316303771?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527316303771?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T20:40:06Z","timestamp":1759092006000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527316303771"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":37,"alternative-id":["S0167527316303771"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2016.02.137","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cost-effectiveness of strain-targeted cardioprotection for prevention of chemotherapy-induced cardiotoxicity","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2016.02.137","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}