{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:34:39Z","timestamp":1792784079682,"version":"4.5.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Italian Ministry of Health for Institutional Research","award":["Ricerca Finalizzata-RF-2010-2318508"],"award-info":[{"award-number":["Ricerca Finalizzata-RF-2010-2318508"]}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","internationaljournalofcardiology.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.ijcard.2016.05.071","type":"journal-article","created":{"date-parts":[[2016,5,31]],"date-time":"2016-05-31T14:46:24Z","timestamp":1464705984000},"page":"105-110","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"special_numbering":"C","title":["Animal models of cardiac cachexia"],"prefix":"10.1016","volume":"219","author":[{"given":"Francesca","family":"Molinari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Malara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Mollace","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Rosano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"Ferraro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2016.05.071_bb0005","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.clnu.2008.06.013","article-title":"Cachexia: a new definition","volume":"27","author":"Evans","year":"2008","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0010","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0167-5273(99)00186-2","article-title":"The role of inflammatory mediators in chronic heart failure: cytokines, nitric oxide, and endothelin-1","volume":"72","author":"Sharma","year":"2000","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0015","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.cardiores.2006.08.018","article-title":"Nutrition, metabolism, and the complex pathophysiology of cachexia in chronic heart failure","volume":"73","author":"von Haehling","year":"2007","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0020","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.clinbiochem.2013.10.025","article-title":"Recent insights on the molecular mechanisms and therapeutic approaches for cardiac cachexia","volume":"47","author":"Martins","year":"2014","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0025","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1053\/euhj.1998.1446","article-title":"Cytokines and neurohormones relating to body composition alterations in the wasting syndrome of chronic heart failure","volume":"20","author":"Anker","year":"1999","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0030","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3389\/fphys.2014.00088","article-title":"Pancreatic cancer cachexia: a review of mechanisms and therapeutics","volume":"5","author":"Tan","year":"2014","journal-title":"Front. Physiol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0035","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1161\/hc4201.097836","article-title":"Elevated circulating level of ghrelin in cachexia associated with chronic heart failure: relationships between ghrelin and anabolic\/catabolic factors","volume":"104","author":"Nagaya","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2016.05.071_bb0040","doi-asserted-by":"crossref","first-page":"3674","DOI":"10.1161\/01.CIR.0000149746.62908.BB","article-title":"Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure","volume":"110","author":"Nagaya","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2016.05.071_bb0045","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S1095-6433(00)00159-8","article-title":"Leptin: an essential regulator of lipid metabolism","volume":"125","author":"Reidy","year":"2000","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0050","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1067\/mcp.2000.104610","article-title":"Venous neuropeptide Y receptor responsiveness in patients with chronic heart failure","volume":"67","author":"Feng","year":"2000","journal-title":"Clin. Pharmacol. Ther."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0055","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/0092-8674(95)90151-5","article-title":"Identification and expression cloning of a leptin receptor","volume":"83","author":"Tartaglia","year":"1995","journal-title":"OB-R. Cell."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0060","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.cca.2014.03.021","article-title":"Myostatin - From the Mighty Mouse to cardiovascular disease and cachexia","volume":"433","author":"Dschietzig","year":"2014","journal-title":"Clin. Chim. Acta; Int. J. Clin. Chem."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0065","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.cell.2010.07.011","article-title":"Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival","volume":"142","author":"Zhou","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.ijcard.2016.05.071_bb0070","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1128\/MCB.01307-13","article-title":"An antibody blocking activin type II receptors induces strong skeletal muscle hypertrophy and protects from atrophy","volume":"34","author":"Lach-Trifilieff","year":"2014","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0075","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/nm1536","article-title":"Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states","volume":"13","author":"Cohn","year":"2007","journal-title":"Nat. Med."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0080","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1097\/01.mco.0000222103.29009.70","article-title":"Angiotensin II as candidate of cardiac cachexia","volume":"9","author":"Delafontaine","year":"2006","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"10.1016\/j.ijcard.2016.05.071_bb0085","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0167-5273(02)00233-4","article-title":"The syndrome of cardiac cachexia","volume":"85","author":"Anker","year":"2002","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0090","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1155\/S0962935193000365","article-title":"Glucocorticoids as cytokine inhibitors: role in neuroendocrine control and therapy of inflammatory diseases","volume":"2","author":"Fantuzzi","year":"1993","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0095","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1001\/archneur.1970.00480200024002","article-title":"Atrophy of skeletal muscle in patients with Cushing's syndrome","volume":"22","author":"Pleasure","year":"1970","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0100","article-title":"The central role of hypothalamic inflammation in the acute illness response and cachexia","author":"Burfeind","year":"2015","journal-title":"Semin. Cell Dev. Biol."},{"issue":"Suppl. 5","key":"10.1016\/j.ijcard.2016.05.071_bb0105","doi-asserted-by":"crossref","first-page":"S63","DOI":"10.1038\/sj.ijo.0801913","article-title":"The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis","volume":"25","author":"Cone","year":"2001","journal-title":"Int. J. Obes. Relat. Metab. Disord.: J. Int. Assoc. Study Obes."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0110","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1378\/chest.115.3.836","article-title":"Cardiac cachexia: a syndrome with impaired survival and immune and neuroendocrine activation","volume":"115","author":"Anker","year":"1999","journal-title":"Chest"},{"key":"10.1016\/j.ijcard.2016.05.071_bb0115","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ijcard.2008.11.146","article-title":"The relationship between tumor necrosis factor-alpha, brain natriuretic peptide and atrial natriuretic peptide in patients with chronic heart failure","volume":"141","author":"Vaz Perez","year":"2010","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.clnu.2006.09.009","article-title":"Fat loss in cachexia\u2013is there a role for adipocyte lipolysis?","volume":"26","author":"Ryden","year":"2007","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0125","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1016\/j.biocel.2013.04.025","article-title":"Muscle wasting in heart failure: An overview","volume":"45","author":"von Haehling","year":"2013","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0130","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1016\/j.ajpath.2011.01.005","article-title":"PGC-1alpha promotes nitric oxide antioxidant defenses and inhibits FOXO signaling against cardiac cachexia in mice","volume":"178","author":"Geng","year":"2011","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0135","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1172\/JCI1362","article-title":"Regulation of Ca2+ signaling in transgenic mouse cardiac myocytes overexpressing calsequestrin","volume":"101","author":"Jones","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0140","doi-asserted-by":"crossref","first-page":"22251","DOI":"10.1074\/jbc.274.32.22251","article-title":"Defective beta-adrenergic receptor signaling precedes the development of dilated cardiomyopathy in transgenic mice with calsequestrin overexpression","volume":"274","author":"Cho","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0145","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1161\/01.CIR.0000014926.32463.89","article-title":"Genetic modifier loci affecting survival and cardiac function in murine dilated cardiomyopathy","volume":"105","author":"Suzuki","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2016.05.071_bb0150","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/0002-8703(91)90227-9","article-title":"The cellular basis of contraction and relaxation in cardiac and vascular smooth muscle","volume":"121","author":"Morgan","year":"1991","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0155","doi-asserted-by":"crossref","first-page":"8958","DOI":"10.1016\/S0021-9258(18)68401-7","article-title":"Complete amino acid sequence of canine cardiac calsequestrin deduced by cDNA cloning","volume":"263","author":"Scott","year":"1988","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0160","doi-asserted-by":"crossref","first-page":"5809","DOI":"10.1073\/pnas.091102398","article-title":"Cardiac beta ARK1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure","volume":"98","author":"Harding","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0165","doi-asserted-by":"crossref","first-page":"599","DOI":"10.2353\/ajpath.2007.060505","article-title":"Oxidative phenotype protects myofibers from pathological insults induced by chronic heart failure in mice","volume":"170","author":"Li","year":"2007","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0170","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1084\/jem.126.4.687","article-title":"Effects of chronic excess salt ingestion. Genetic influence on the development of salt hypertension in parabiotic rats: evidence for a humoral factor","volume":"126","author":"Dahl","year":"1967","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0175","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.ijcard.2011.07.056","article-title":"Analysis of liver metabolism in a rat model of heart failure","volume":"161","author":"Kato","year":"2012","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0180","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.lfs.2015.06.021","article-title":"Branched-chain amino acids ameliorate heart failure with cardiac cachexia in rats","volume":"137","author":"Tanada","year":"2015","journal-title":"Life Sci."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0185","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1152\/japplphysiol.90884.2008","article-title":"Anti-TNF treatment reduces rat skeletal muscle wasting in monocrotaline-induced cardiac cachexia","volume":"105","author":"Steffen","year":"2008","journal-title":"J. Appl. Physiol. (1985)"},{"key":"10.1016\/j.ijcard.2016.05.071_bb0190","doi-asserted-by":"crossref","first-page":"L363","DOI":"10.1152\/ajplung.00212.2011","article-title":"The monocrotaline model of pulmonary hypertension in perspective","volume":"302","author":"Gomez-Arroyo","year":"2012","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0195","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1136\/thx.22.2.176","article-title":"Pulmonary hypertension produced in rats by ingestion of Crotalaria spectabilis seeds","volume":"22","author":"Kay","year":"1967","journal-title":"Thorax"},{"key":"10.1016\/j.ijcard.2016.05.071_bb0200","first-page":"H1484","article-title":"Endothelial injury and vascular reactivity in monocrotaline pulmonary hypertension","volume":"255","author":"Rosenberg","year":"1988","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0205","doi-asserted-by":"crossref","first-page":"L1013","DOI":"10.1152\/ajplung.00217.2009","article-title":"Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure","volume":"297","author":"Stenmark","year":"2009","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0210","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/j.echo.2006.04.036","article-title":"Sequence of echocardiographic changes during development of right ventricular failure in rat","volume":"19","author":"Hardziyenka","year":"2006","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0215","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.jacc.2009.04.009","article-title":"Development and pathology of pulmonary hypertension","volume":"54","author":"Tuder","year":"2009","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0220","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1080\/10937409809524557","article-title":"Chronic pulmonary hypertension\u2014the monocrotaline model and involvement of the hemostatic system","volume":"1","author":"Schultze","year":"1998","journal-title":"J. Toxicol. Environ. Health B Crit. Rev."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0225","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0062702","article-title":"Diaphragm atrophy and contractile dysfunction in a murine model of pulmonary hypertension","volume":"8","author":"Ahn","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.ijcard.2016.05.071_bb0230","doi-asserted-by":"crossref","first-page":"2411","DOI":"10.1016\/0006-2952(89)90084-1","article-title":"Monocrotaline-induced cardiopulmonary injury in rats. Modification by the neutrophil elastase inhibitor SC39026","volume":"38","author":"Molteni","year":"1989","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0235","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1161\/CIRCRESAHA.110.223925","article-title":"A novel and efficient model of coronary artery ligation and myocardial infarction in the mouse","volume":"107","author":"Gao","year":"2010","journal-title":"Circ. Res."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0240","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0143221","article-title":"Rapid and efficient production of coronary artery ligation and myocardial infarction in mice using surgical clips","volume":"10","author":"Andrade","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.ijcard.2016.05.071_bb0245","first-page":"H2147","article-title":"Myocardial ischemia and reperfusion: a murine model","volume":"269","author":"Michael","year":"1995","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0250","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1677\/JOE-09-0397","article-title":"Genetic and pharmacologic blockade of central melanocortin signaling attenuates cardiac cachexia in rodent models of heart failure","volume":"206","author":"Scarlett","year":"2010","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0255","doi-asserted-by":"crossref","first-page":"8277","DOI":"10.1073\/pnas.88.18.8277","article-title":"Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy","volume":"88","author":"Rockman","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0260","doi-asserted-by":"crossref","DOI":"10.3791\/1729","article-title":"Transverse aortic constriction in mice","author":"de Almeida","year":"2010","journal-title":"J. Vis. Exp.: JoVE"},{"key":"10.1016\/j.ijcard.2016.05.071_bb0265","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s10741-012-9305-3","article-title":"Rodent models of heart failure: an updated review","volume":"18","author":"Gomes","year":"2013","journal-title":"Heart Fail. Rev."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0270","doi-asserted-by":"crossref","first-page":"R1325","DOI":"10.1152\/ajpregu.00320.2004","article-title":"Aortic banding in rat as a model to investigate malnutrition associated with heart failure","volume":"288","author":"Helies-Toussaint","year":"2005","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0275","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1161\/01.RES.73.1.184","article-title":"Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding","volume":"73","author":"Feldman","year":"1993","journal-title":"Circ. Res."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0280","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.ijcard.2009.01.060","article-title":"The influence of age and sex on disease development in a novel animal model of cardiac cachexia","volume":"133","author":"Palus","year":"2009","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0285","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1517\/17460440903300842","article-title":"Animal models of anorexia and cachexia","volume":"4","author":"Deboer","year":"2009","journal-title":"Expert Opin. Drug Discovery"},{"key":"10.1016\/j.ijcard.2016.05.071_bb0290","doi-asserted-by":"crossref","first-page":"H771","DOI":"10.1152\/ajpheart.00282.2015","article-title":"A mouse model of heart failure with preserved ejection fraction due to chronic infusion of a low subpressor dose of angiotensin II","volume":"309","author":"Regan","year":"2015","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0295","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.clnu.2011.12.008","article-title":"Sexual dimorphism modulates the impact of cancer cachexia on lower limb muscle mass and function","volume":"31","author":"Stephens","year":"2012","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0300","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1515\/cclm-2012-0849","article-title":"Gender medicine: a task for the third millennium","volume":"51","author":"Baggio","year":"2013","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.ijcard.2016.05.071_bb0305","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.ijcard.2014.11.019","article-title":"Need for gender-specific pre-analytical testing: the dark side of the moon in laboratory testing","volume":"179","author":"Franconi","year":"2015","journal-title":"Int. J. Cardiol."}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527316309950?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527316309950?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T18:02:05Z","timestamp":1656612125000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527316309950"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":61,"alternative-id":["S0167527316309950"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2016.05.071","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Animal models of cardiac cachexia","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2016.05.071","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}