{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T20:45:06Z","timestamp":1793133906185,"version":"4.5.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","internationaljournalofcardiology.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.ijcard.2016.12.150","type":"journal-article","created":{"date-parts":[[2016,12,26]],"date-time":"2016-12-26T14:16:07Z","timestamp":1482761767000},"page":"61-67","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":124,"special_numbering":"C","title":["Two-year outcomes after percutaneous coronary intervention of calcified lesions with drug-eluting stents"],"prefix":"10.1016","volume":"231","author":[{"given":"Philippe","family":"G\u00e9n\u00e9reux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Redfors","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9322-1926","authenticated-orcid":false,"given":"Bernhard","family":"Witzenbichler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5849-1744","authenticated-orcid":false,"given":"Marie-Pier","family":"Arsenault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giora","family":"Weisz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas D.","family":"Stuckey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Rinaldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz-Josef","family":"Neumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Christopher Metzger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy D.","family":"Henry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Cox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter L.","family":"Duffy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Ernest L.","family":"Mazzaferri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominic P.","family":"Francese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Marquis-Gravel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary S.","family":"Mintz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay J.","family":"Kirtane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiko","family":"Maehara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana","family":"Mehran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregg W.","family":"Stone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.ijcard.2016.12.150_bb0005","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1161\/01.CIR.91.7.1959","article-title":"Patterns of calcification in coronary artery disease. A statistical analysis of intravascular ultrasound and coronary angiography in 1155 lesions","volume":"91","author":"Mintz","year":"1995","journal-title":"Circulation"},{"issue":"18","key":"10.1016\/j.ijcard.2016.12.150_bb0010","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1016\/j.jacc.2014.01.034","volume":"63","author":"Genereux","year":"2014","journal-title":"J. Am. Coll. Cardiol."},{"issue":"17","key":"10.1016\/j.ijcard.2016.12.150_bb0015","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1016\/j.jacc.2014.01.017","article-title":"Coronary artery calcification: pathogenesis and prognostic implications","volume":"63","author":"Madhavan","year":"2014","journal-title":"J. Am. Coll. Cardiol."},{"issue":"15","key":"10.1016\/j.ijcard.2016.12.150_bb0020","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1136\/heartjnl-2013-305180","article-title":"Prognostic implications of coronary calcification in patients with obstructive coronary artery disease treated by percutaneous coronary intervention: a patient-level pooled analysis of 7 contemporary stent trials","volume":"100","author":"Bourantas","year":"2014","journal-title":"Heart"},{"issue":"1","key":"10.1016\/j.ijcard.2016.12.150_bb0025","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/ccd.22613","article-title":"Percutaneous coronary intervention of moderate to severe calcified coronary lesions: insights from the National Heart, Lung, and Blood Institute Dynamic Registry","volume":"77","author":"Bangalore","year":"2011","journal-title":"Catheter. Cardiovasc. Interv."},{"issue":"1","key":"10.1016\/j.ijcard.2016.12.150_bb0030","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jcin.2009.10.022","article-title":"Incidence and predictors of very late (>or =4years) major cardiac adverse events in the DESIRE (drug-eluting stents in the real world)-late registry","volume":"3","author":"Costa","year":"2010","journal-title":"JACC Cardiovasc. Interv."},{"issue":"11","key":"10.1016\/j.ijcard.2016.12.150_bb0035","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1016\/j.amjcard.2013.07.038","article-title":"Impact of the severity of coronary artery calcification on clinical events in patients undergoing coronary artery bypass grafting (from the acute catheterization and urgent intervention triage strategy trial)","volume":"112","author":"Ertelt","year":"2013","journal-title":"Am. J. Cardiol."},{"issue":"2","key":"10.1016\/j.ijcard.2016.12.150_bb0040","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1056\/NEJM197907123010201","article-title":"Nonoperative dilatation of coronary-artery stenosis: percutaneous transluminal coronary angioplasty","volume":"301","author":"Gruntzig","year":"1979","journal-title":"N. Engl. J. Med."},{"issue":"1","key":"10.1016\/j.ijcard.2016.12.150_bb0045","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1056\/NEJMra1112570","article-title":"A tale of coronary artery disease and myocardial infarction. [Erratum appears in N Engl J Med. 2012 Mar 8;366(10):970]","volume":"366","author":"Nabel","year":"2012","journal-title":"N. Engl. J. Med."},{"issue":"2","key":"10.1016\/j.ijcard.2016.12.150_bb0050","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1002\/ccd.25545","article-title":"Prognostic implications of severe coronary calcification in patients undergoing coronary artery bypass surgery: an analysis of the SYNTAX study","volume":"85","author":"Bourantas","year":"2015","journal-title":"Catheter. Cardiovasc. Interv."},{"issue":"18","key":"10.1016\/j.ijcard.2016.12.150_bb0055","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1056\/NEJMoa0910496","article-title":"Everolimus-eluting versus paclitaxel-eluting stents in coronary artery disease","volume":"362","author":"Stone","year":"2010","journal-title":"N. Engl. J. Med."},{"issue":"9","key":"10.1016\/j.ijcard.2016.12.150_bb0060","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/j.jcin.2013.05.005","volume":"6","author":"Dangas","year":"2013","journal-title":"JACC Cardiovasc. Interv."},{"issue":"10","key":"10.1016\/j.ijcard.2016.12.150_bb0065","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1161\/CIRCULATIONAHA.111.063644","volume":"125","author":"Jensen","year":"2012","journal-title":"Circulation"},{"issue":"18","key":"10.1016\/j.ijcard.2016.12.150_bb0070","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1016\/j.jacc.2014.01.035","article-title":"The curse of target lesion calcification: still active after all these years","volume":"63","author":"Waters","year":"2014","journal-title":"J. Am. Coll. Cardiol."},{"issue":"9892","key":"10.1016\/j.ijcard.2016.12.150_bb0075","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/S0140-6736(13)61170-8","article-title":"Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): a prospective multicentre registry study","volume":"382","author":"Stone","year":"2013","journal-title":"Lancet"},{"issue":"21","key":"10.1016\/j.ijcard.2016.12.150_bb0080","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1056\/NEJMoa062437","article-title":"Bivalirudin for patients with acute coronary syndromes","volume":"355","author":"Stone","year":"2006","journal-title":"N. Engl. J. Med."},{"issue":"5","key":"10.1016\/j.ijcard.2016.12.150_bb0085","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/j.ahj.2004.04.036","article-title":"Acute catheterization and urgent intervention triage strategY (ACUITY) trial: study design and rationale","volume":"148","author":"Stone","year":"2004","journal-title":"Am. Heart J."},{"issue":"17","key":"10.1016\/j.ijcard.2016.12.150_bb0090","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1161\/CIRCULATIONAHA.106.685313","article-title":"Clinical end points in coronary stent trials: a case for standardized definitions","volume":"115","author":"Cutlip","year":"2007","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.ijcard.2016.12.150_bb0095","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.amjcard.2013.11.053","volume":"113","author":"Genereux","year":"2014","journal-title":"Am. J. Cardiol."},{"issue":"4","key":"10.1016\/j.ijcard.2016.12.150_bb0100","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.carrev.2005.08.008","article-title":"Impact of vessel calcification on outcomes after coronary stenting","volume":"6","author":"Mosseri","year":"2005","journal-title":"Cardiovasc. Revasc. Med."},{"issue":"1","key":"10.1016\/j.ijcard.2016.12.150_bb0105","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.carrev.2007.07.004","article-title":"Impact of lesion calcification on clinical and angiographic outcome after sirolimus-eluting stent implantation in real-world patients","volume":"9","author":"Kawaguchi","year":"2008","journal-title":"Cardiovasc. Revasc. Med."},{"issue":"9","key":"10.1016\/j.ijcard.2016.12.150_bb0110","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1016\/j.amjcard.2005.06.064","article-title":"Impact of coronary culprit lesion calcium in patients undergoing paclitaxel-eluting stent implantation (a TAXUS-IV sub study)","volume":"96","author":"Moussa","year":"2005","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ijcard.2016.12.150_bb0115","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0002-8703(99)70463-1","article-title":"Impact of target lesion calcification on coronary stent expansion after rotational atherectomy","volume":"137","author":"Henneke","year":"1999","journal-title":"Am. Heart J."},{"issue":"12","key":"10.1016\/j.ijcard.2016.12.150_bb0120","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1016\/j.amjcard.2015.03.009","article-title":"Orbital atherectomy for treating de novo severely calcified coronary narrowing (1-year results from the pivotal ORBIT II trial)","volume":"115","author":"G\u00e9n\u00e9reux","year":"2015","journal-title":"Am. J. Cardiol."},{"issue":"5","key":"10.1016\/j.ijcard.2016.12.150_bb0125","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.jcin.2014.01.158","article-title":"Pivotal trial to evaluate the safety and efficacy of the orbital atherectomy system in treating de novo, severely calcified coronary lesions (ORBIT II)","volume":"7","author":"Chambers","year":"2014","journal-title":"JACC Cardiovasc. Interv."},{"issue":"1","key":"10.1016\/j.ijcard.2016.12.150_bb0130","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jcin.2012.07.017","article-title":"High-speed rotational atherectomy before paclitaxel-eluting stent implantation in complex calcified coronary lesions: the randomized ROTAXUS (rotational atherectomy prior to taxus stent treatment for complex native coronary artery disease) trial","volume":"6","author":"Abdel-Wahab","year":"2013","journal-title":"JACC Cardiovasc. Interv."},{"issue":"2","key":"10.1016\/j.ijcard.2016.12.150_bb0135","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/0002-8703(94)90133-3","article-title":"Coronary calcium and atherosclerosis by ultrafast computed tomography in asymptomatic men and women: relation to age and risk factors","volume":"127","author":"Wong","year":"1994","journal-title":"Am. Heart J."},{"issue":"2","key":"10.1016\/j.ijcard.2016.12.150_bb0140","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/S0735-1097(96)00479-2","article-title":"Determinants and correlates of target lesion calcium in coronary artery disease: a clinical, angiographic and intravascular ultrasound study","volume":"29","author":"Mintz","year":"1997","journal-title":"J. Am. Coll. Cardiol."},{"issue":"2","key":"10.1016\/j.ijcard.2016.12.150_bb0145","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jacc.2006.10.038","article-title":"Coronary artery calcification and changes in atheroma burden in response to established medical therapies","volume":"49","author":"Nicholls","year":"2007","journal-title":"J. Am. Coll. Cardiol."},{"issue":"5","key":"10.1016\/j.ijcard.2016.12.150_bb0150","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/0735-1097(92)90371-S","article-title":"Target lesion calcification in coronary artery disease: an intravascular ultrasound study","volume":"20","author":"Mintz","year":"1992","journal-title":"J. Am. Coll. Cardiol."},{"issue":"3 Suppl","key":"10.1016\/j.ijcard.2016.12.150_bb0155","doi-asserted-by":"crossref","first-page":"S53","DOI":"10.1016\/j.jcmg.2011.12.008","article-title":"Coronary plaque composition, morphology, and outcomes in patients with and without chronic kidney disease presenting with acute coronary syndromes","volume":"5","author":"Baber","year":"2012","journal-title":"JACC Cardiovasc. Interv."},{"issue":"4","key":"10.1016\/j.ijcard.2016.12.150_bb0160","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1213\/ANE.0b013e3182a44cb9","article-title":"Statistical grand rounds: understanding the mechanism: mediation analysis in randomized and nonrandomized studies","volume":"117","author":"Mascha","year":"2013","journal-title":"Anesth. Analg."},{"issue":"9","key":"10.1016\/j.ijcard.2016.12.150_bb0165","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.jacc.2015.06.1323","article-title":"Incidence, predictors, and impact of post-discharge bleeding after percutaneous coronary intervention","volume":"66","author":"Genereux","year":"2015","journal-title":"J. Am. Coll. Cardiol."},{"issue":"12","key":"10.1016\/j.ijcard.2016.12.150_bb0170","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1093\/eurheartj\/ehp110","article-title":"Associations of major bleeding and myocardial infarction with the incidence and timing of mortality in patients presenting with non-ST-elevation acute coronary syndromes: a risk model from the ACUITY trial","volume":"30","author":"Mehran","year":"2009","journal-title":"Eur. Heart J."},{"issue":"17","key":"10.1016\/j.ijcard.2016.12.150_bb0175","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1016\/j.jacc.2011.07.021","article-title":"Impact of in-hospital major bleeding on late clinical outcomes after primary percutaneous coronary intervention in acute myocardial infarction the HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trial","volume":"58","author":"Suh","year":"2011","journal-title":"J. Am. Coll. Cardiol."},{"issue":"20","key":"10.1016\/j.ijcard.2016.12.150_bb0180","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1016\/j.jacc.2015.03.567","article-title":"Bleeding avoidance strategies during percutaneous coronary interventions","volume":"65","author":"Singh","year":"2015","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2016.12.150_bb0185","article-title":"Precision medicine to improve use of bleeding avoidance strategies and reduce bleeding in patients undergoing percutaneous coronary intervention: prospective cohort study before and after implementation of personalized bleeding risks","volume":"350","author":"Spertus","year":"2015","journal-title":"BMJ (Clin. Res. Ed.)"},{"issue":"6","key":"10.1016\/j.ijcard.2016.12.150_bb0190","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1161\/CIRCOUTCOMES.114.001275","article-title":"Real-time decision support to guide percutaneous coronary intervention bleeding avoidance strategies effectively changes practice patterns","volume":"7","author":"Strauss","year":"2014","journal-title":"Circ. Cardiovasc. Qual. Outcomes"},{"issue":"1","key":"10.1016\/j.ijcard.2016.12.150_bb0195","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jacc.2011.02.039","article-title":"Bleeding avoidance strategies. Consensus and controversy","volume":"58","author":"Dauerman","year":"2011","journal-title":"J. Am. Coll. Cardiol."},{"issue":"9591","key":"10.1016\/j.ijcard.2016.12.150_bb0200","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0140-6736(07)61444-5","article-title":"Outcomes associated with drug-eluting and bare-metal stents: a collaborative network meta-analysis","volume":"370","author":"Stettler","year":"2007","journal-title":"Lancet"},{"issue":"23","key":"10.1016\/j.ijcard.2016.12.150_bb0205","doi-asserted-by":"crossref","first-page":"2873","DOI":"10.1161\/CIRCULATIONAHA.112.097014","article-title":"Short- and long-term outcomes with drug-eluting and bare-metal coronary stents: a mixed-treatment comparison analysis of 117 762 patient-years of follow-up from randomized trials","volume":"125","author":"Bangalore","year":"2012","journal-title":"Circulation"},{"issue":"9710","key":"10.1016\/j.ijcard.2016.12.150_bb0210","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0140-6736(09)62127-9","article-title":"Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice (COMPARE): a randomised trial","volume":"375","author":"Kedhi","year":"2010","journal-title":"Lancet"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527316344667?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527316344667?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T11:20:55Z","timestamp":1536146455000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527316344667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":42,"alternative-id":["S0167527316344667"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2016.12.150","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Two-year outcomes after percutaneous coronary intervention of calcified lesions with drug-eluting stents","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2016.12.150","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}