{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:35:07Z","timestamp":1777908907866,"version":"3.51.4"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.ijcard.2017.05.091","type":"journal-article","created":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T18:49:37Z","timestamp":1504291777000},"page":"20-25","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Sex differences in the effect of diabetes mellitus on platelet reactivity and coronary thrombosis: From the Assessment of Dual Antiplatelet Therapy with Drug-Eluting Stents (ADAPT-DES) study"],"prefix":"10.1016","volume":"246","author":[{"given":"Gennaro","family":"Giustino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bj\u00f6rn","family":"Redfors","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roxana","family":"Mehran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajay J.","family":"Kirtane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Usman","family":"Baber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"G\u00e9n\u00e9reux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Witzenbichler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz-Josef","family":"Neumann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giora","family":"Weisz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Maehara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Rinaldi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. Christopher","family":"Metzger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy D.","family":"Henry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Cox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter L.","family":"Duffy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Ernest L.","family":"Mazzaferri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce R.","family":"Brodie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas D.","family":"Stuckey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George D.","family":"Dangas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sorin J.","family":"Brener","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ozgu Ozan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregg W.","family":"Stone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2017.05.091_bb0005","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1161\/01.CIR.100.10.1134","article-title":"Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association","volume":"100","author":"Grundy","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2017.05.091_bb0010","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.114.001944","article-title":"Percutaneous coronary interventions in the diabetic patient: where do we stand?","volume":"8","author":"Bittl","year":"2015","journal-title":"Circ. Cardiovasc. Interv."},{"key":"10.1016\/j.ijcard.2017.05.091_bb0015","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1161\/CIR.0000000000000230","article-title":"Update on prevention of cardiovascular disease in adults with type 2 diabetes mellitus in light of recent evidence: a scientific statement from the American Heart Association and the American Diabetes Association","volume":"132","author":"Fox","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2017.05.091_bb0020","doi-asserted-by":"crossref","first-page":"2424","DOI":"10.1161\/CIR.0000000000000343","article-title":"Sex differences in the cardiovascular consequences of diabetes mellitus: a scientific statement from the American Heart Association","volume":"132","author":"Regensteiner","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2017.05.091_bb0025","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.jacc.2015.01.024","article-title":"DAPT duration after DES: what is the \u201cmandatory\u201d duration?","volume":"65","author":"Mehran","year":"2015","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2017.05.091_bb0030","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.jacc.2015.01.039","article-title":"Duration of dual antiplatelet therapy after drug-eluting stent implantation: a systematic review and meta-analysis of randomized controlled trials","volume":"65","author":"Giustino","year":"2015","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2017.05.091_bb0035","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/S0140-6736(13)61170-8","article-title":"Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): a prospective multicentre registry study","volume":"382","author":"Stone","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.ijcard.2017.05.091_bb0040","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1016\/j.jacc.2013.07.101","article-title":"Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding","volume":"62","author":"Tantry","year":"2013","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2017.05.091_bb0045","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.amjcard.2015.06.010","volume":"116","author":"Giustino","year":"2015","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ijcard.2017.05.091_bb0050","doi-asserted-by":"crossref","first-page":"S62","DOI":"10.1016\/j.jcmg.2012.02.003","article-title":"Gender and the extent of coronary atherosclerosis, plaque composition, and clinical outcomes in acute coronary syndromes","volume":"5","author":"Lansky","year":"2012","journal-title":"JACC Cardiovasc. Imaging"},{"key":"10.1016\/j.ijcard.2017.05.091_bb0055","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1007\/s00125-005-1730-6","article-title":"Sex differences in cardiovascular and total mortality among diabetic and non-diabetic individuals with or without history of myocardial infarction","volume":"48","author":"Hu","year":"2005","journal-title":"Diabetologia"},{"key":"10.1016\/j.ijcard.2017.05.091_bb0060","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/S1049-3867(03)00035-5","article-title":"Improving women's quality of care for cardiovascular disease and diabetes: the feasibility and desirability of stratified reporting of objective performance measures","volume":"13","author":"Bird","year":"2003","journal-title":"Womens Health Issues"},{"key":"10.1016\/j.ijcard.2017.05.091_bb0065","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1016\/j.jacc.2016.07.760","article-title":"Efficacy and safety of dual antiplatelet therapy after complex PCI","volume":"68","author":"Giustino","year":"2016","journal-title":"J. Am. Coll. Cardiol."},{"issue":"12","key":"10.1016\/j.ijcard.2017.05.091_bb0070","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1016\/j.amjcard.2016.03.034","article-title":"Impact of anemia on platelet reactivity and ischemic and bleeding risk from the assessment of dual antiplatelet therapy with drug-eluting stents study","volume":"117","author":"Giustino","year":"2016","journal-title":"Am. J. Cardiol."},{"issue":"11","key":"10.1016\/j.ijcard.2017.05.091_bb0075","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1016\/j.amjcard.2016.03.001","article-title":"Relation between platelet count and platelet reactivity to thrombotic and bleeding risk: from the assessment of dual antiplatelet therapy with drug-eluting stents study","volume":"117","author":"Giustino","year":"2016","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ijcard.2017.05.091_bb0080","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.jacc.2010.04.047","article-title":"Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate","volume":"56","author":"Bonello","year":"2010","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2017.05.091_bb0085","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1161\/CIRCULATIONAHA.109.913376","article-title":"Diabetes and antiplatelet therapy in acute coronary syndrome","volume":"123","author":"Ferreiro","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2017.05.091_bb0090","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/j.jcmg.2014.04.019","article-title":"Sex-related differences of coronary atherosclerosis regression following maximally intensive statin therapy: insights from SATURN","volume":"7","author":"Puri","year":"2014","journal-title":"JACC Cardiovasc. imaging"},{"key":"10.1016\/j.ijcard.2017.05.091_bb0095","doi-asserted-by":"crossref","first-page":"354","DOI":"10.2337\/dc06-1772","article-title":"Sex differences in endothelial function markers before conversion to pre-diabetes: does the clock start ticking earlier among women? The Western New York Study","volume":"30","author":"Donahue","year":"2007","journal-title":"Diabetes Care"},{"key":"10.1016\/j.ijcard.2017.05.091_bb0100","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1161\/CIRCULATIONAHA.111.029165","article-title":"Platelet reactivity and cardiovascular outcomes after percutaneous coronary intervention: a time-dependent analysis of the Gauging Responsiveness with a VerifyNow P2Y12 assay: impact on thrombosis and safety (GRAVITAS) trial","volume":"124","author":"Price","year":"2011","journal-title":"Circulation"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527317315395?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527317315395?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,26]],"date-time":"2022-06-26T07:41:51Z","timestamp":1656229311000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527317315395"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":20,"alternative-id":["S0167527317315395"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2017.05.091","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sex differences in the effect of diabetes mellitus on platelet reactivity and coronary thrombosis: From the Assessment of Dual Antiplatelet Therapy with Drug-Eluting Stents (ADAPT-DES) study","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2017.05.091","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}