{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T23:18:26Z","timestamp":1768691906661,"version":"3.49.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","internationaljournalofcardiology.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.ijcard.2017.11.060","type":"journal-article","created":{"date-parts":[[2017,11,22]],"date-time":"2017-11-22T19:16:16Z","timestamp":1511378176000},"page":"122-127","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["De novo mitral regurgitation as a cause of heart failure exacerbation in patients with hypertrophic cardiomyopathy"],"prefix":"10.1016","volume":"252","author":[{"given":"Rafael","family":"Kuperstein","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Klempfner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Efrat","family":"Ofek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elad","family":"Maor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dov","family":"Freimark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonid","family":"Sternik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilan","family":"Goldenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ehud","family":"Raanani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Arad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2017.11.060_bb0005","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1093\/eurheartj\/ehu284","article-title":"2014 ESC guidelines on diagnosis and management of hypertrophic cardiomyopathy. The task force for the diagnosis and management of hypertrophic cardiomyopathy of the European Society of Cardiology","volume":"35","author":"Elliot","year":"2014","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0010","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/S0140-6736(12)60397-3","article-title":"Hypertrophic cardiomyopathy","volume":"381","author":"Maron","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.ijcard.2017.11.060_bb0015","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1161\/CIRCULATIONAHA.106.644682","article-title":"Hypertrophic cardiomyopathy is predominantly a disease of left ventricular outflow tract obstruction","volume":"114","author":"Maron","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2017.11.060_bb0020","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1016\/j.jacc.2016.01.071","article-title":"The mitral valve in obstructive cardiomyopathy. A test in context","volume":"67","author":"Sherrid","year":"2016","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0025","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/0735-1097(92)90135-A","article-title":"Transesophageal Doppler echocardiography in obstructive hypertrophic cardiomyopathy: clarification of pathophysiology and importance of intra operative decision making","volume":"20","author":"Grigg","year":"1992","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0030","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1161\/01.CIR.98.9.856","article-title":"Mechanism of mitral regurgitation in hypertrophic cardiomyopathy: mismatch of posterior to anterior leaflet length and mobility","volume":"98","author":"Schwammenthall","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2017.11.060_bb0035","doi-asserted-by":"crossref","first-page":"1651-1560","DOI":"10.1161\/01.CIR.85.5.1651","article-title":"Diversity of structural mitral valve alterations in hypertrophic cardiomyopathy","volume":"85","author":"Klues","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2017.11.060_bb0040","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1161\/01.CIR.84.3.1188","article-title":"Anomalous insertion of papillary muscle directly into anterior mitral leaflet in hypertrophic cardiomyopathy. Significance in producing left ventricular outflow obstruction","volume":"84","author":"Klues","year":"1991","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2017.11.060_bb0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0033-0620(85)90024-6","article-title":"Hypertrophic cardiomyopathy. The importance of the site and extent of hypertrophy: a review","volume":"28","author":"Wigle","year":"1985","journal-title":"Prog. Cardiovasc. Dis."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0050","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/0002-9149(69)90457-3","article-title":"Mitral regurgitation in muscular subaortic stenosis","volume":"24","author":"Wigle","year":"1969","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0055","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/0735-1097(92)90166-K","article-title":"Mitral regurgitation due to ruptured chordate tendinae in patients with hypertrophic obstructive cardiomyopathy","volume":"20","author":"Zhu","year":"1992","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0060","doi-asserted-by":"crossref","first-page":"292","DOI":"10.4070\/kcj.2009.39.7.292","article-title":"Acute mitral regurgitation due to spontaneous chordal rupture in a patient with hypertrophic obstructive cardiomyopathy","volume":"39","author":"Yang","year":"2009","journal-title":"Korean Circ J"},{"key":"10.1016\/j.ijcard.2017.11.060_bb0065","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0735-1097(92)90137-C","article-title":"Coexistence of mitral valve prolapse in a consecutive group of 528 patients with hypertrophic cardiomyopathy assessed with echocardiography","volume":"20","author":"Petrone","year":"1992","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0070","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/ejechocard\/jeq031","article-title":"European Association of Echocardiography recommendations for the assessment of valvular regurgitation: part 2 mitral and tricuspid regurgitation","volume":"11","author":"Lancellotti","year":"2010","journal-title":"Eur. J. Echocardiogr."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0075","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1001\/jama.287.10.1308","article-title":"Hypertrophic cardiomyopathy: a systematic review","volume":"287","author":"Maron","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.ijcard.2017.11.060_bb0080","doi-asserted-by":"crossref","first-page":"2158","DOI":"10.1161\/CIRCULATIONAHA.113.006702","article-title":"Epidemiology and pathophysiology of mitral valve prolapse: new insights into disease progression, genetics and molecular basis","volume":"129","author":"Delling","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2017.11.060_bb0085","doi-asserted-by":"crossref","first-page":"787","DOI":"10.7326\/0003-4819-149-11-200812020-00003","article-title":"Sex difference in the morphology and outcomes of mitral valve prolapse: a cohort study","volume":"149","author":"Avierinos","year":"2008","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0090","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.jcmg.2007.12.005","article-title":"Outcome of mitral regurgitation due to flail mitral leaflets","volume":"1","author":"Grigioni","year":"2008","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.ijcard.2017.11.060_bb0095","article-title":"Mitral regurgitation in hypertrophic obstructive cardiomyopathy: relationship to obstruction and relief with myectomy","volume":"36","author":"EH","year":"2000","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0100","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1161\/01.CIR.55.4.622","article-title":"Echocardiographic associations between mitral valve prolapsed and asymmetric septal hypertrophy","volume":"55","author":"Chandraratna","year":"1977","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2017.11.060_bb0105","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/j.athoracsur.2008.01.061","article-title":"Mitral valve abnormalities in hypertrophic cardiomyopathy: echocardiographic features and surgical outcome","volume":"85","author":"Kaple","year":"2008","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0110","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.acvd.2015.01.003","article-title":"Rupture of mitral valve chordae in hypertrophic cardiomyopathy","volume":"108","author":"Boissier","year":"2015","journal-title":"Arch. Cardiovasc. Dis."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0115","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1016\/j.jacc.2016.07.735","article-title":"Mitral regurgitation in patients with hypertrophic obstructive cardiomyopathy. Implications for concomitant valve procedures","volume":"68","author":"Hong","year":"2016","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0120","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1016\/j.jacc.2014.04.090","article-title":"Vector flow mapping in hypertrophic cardiomyopathy to assess the relationship of early systolic left ventricular flow and the mitral valve","volume":"64","author":"Ro","year":"2014","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0125","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.acvd.2013.05.002","article-title":"Relation between left ventricular outflow tract obstruction and left ventricular shape in patients with hypertrophic cardiomyopathy; a cardiac magnetic resonance study","volume":"106","author":"Martin","year":"2013","journal-title":"Arch. Cardiovasc. Dis."},{"key":"10.1016\/j.ijcard.2017.11.060_bb0130","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1136\/hrt.2009.166777","article-title":"Steep left ventricle to aortic root angle and hypertrophic cardiomyopathy: study of a novel association using three dimensional multimodality imaging","volume":"95","author":"Kwon","year":"2009","journal-title":"Heart"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527317352087?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527317352087?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T14:42:03Z","timestamp":1542897723000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527317352087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":26,"alternative-id":["S0167527317352087"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2017.11.060","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"De novo mitral regurgitation as a cause of heart failure exacerbation in patients with hypertrophic cardiomyopathy","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2017.11.060","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}