{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T10:41:29Z","timestamp":1789296089532,"version":"build-2803163510"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Geschwister-Kessel-Stiftung, Langenenslingen, Germany (CSZ)"},{"name":"University of Tuebingen, Germany (KM)","award":["2241-0-0"],"award-info":[{"award-number":["2241-0-0"]}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","internationaljournalofcardiology.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.ijcard.2018.04.025","type":"journal-article","created":{"date-parts":[[2018,4,7]],"date-time":"2018-04-07T09:05:14Z","timestamp":1523091914000},"page":"104-110","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Galectin-3 is associated with left ventricular reverse remodeling and outcome after percutaneous mitral valve repair"],"prefix":"10.1016","volume":"263","author":[{"given":"Christine S.","family":"Zuern","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niklas","family":"Floss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris I.","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Eick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Duckheim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Patzelt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meinrad","family":"Gawaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas E.","family":"May","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin A.L.","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2018.04.025_bb0005","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1093\/eurjhf\/hft046","article-title":"One year clinical efficacy and reverse cardiac remodelling in patients with severe mitral regurgitation and reduced ejection fraction after MitraClip implantation","volume":"15","author":"Pleger","year":"2013","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0010","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1093\/ehjci\/jet141","article-title":"Integrated reverse left and right ventricular remodelling after MitraClip implantation in functional mitral regurgitation: an echocardiographic study","volume":"15","author":"Giannini","year":"2014","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"issue":"2","key":"10.1016\/j.ijcard.2018.04.025_bb0015","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1093\/ehjci\/jex011","article-title":"Mitral valve repair for secondary mitral regurgitation in non-ischaemic dilated cardiomyopathy is associated with left ventricular reverse remodelling and increase of forward flow","volume":"19","author":"Kamperidis","year":"2018","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"10.1016\/j.ijcard.2018.04.025_bb0020","first-page":"309","article-title":"Left atrial and left ventricular function and remodeling following percutaneous mitral valve repair","volume":"25","author":"Rammos","year":"2016","journal-title":"J. Heart Valve Dis."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0025","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.ejcts.2004.12.031","article-title":"Preoperative left ventricular dimensions predict reverse remodeling following restrictive mitral annuloplasty in ischemic mitral regurgitation","volume":"27","author":"Braun","year":"2005","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0030","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1093\/eurjhf\/hfp097","article-title":"Galectin-3: a novel mediator of heart failure development and progression","volume":"11","author":"de Boer","year":"2009","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11897-010-0004-x","article-title":"Galectin-3 in cardiac remodeling and heart failure","volume":"7","author":"de Boer","year":"2010","journal-title":"Curr. Heart Fail. Rep."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0040","doi-asserted-by":"crossref","first-page":"3121","DOI":"10.1161\/01.CIR.0000147181.65298.4D","article-title":"Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction","volume":"110","author":"Sharma","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2018.04.025_bb0045","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.1600-065X.2009.00794.x","article-title":"The regulation of inflammation by galectin-3","volume":"230","author":"Henderson","year":"2009","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0050","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1093\/eurjhf\/hft056","article-title":"Galectin-3 and left ventricular reverse remodelling after surgical mitral valve repair","volume":"15","author":"Kortekaas","year":"2013","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0055","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1016\/j.ijcard.2014.10.010","article-title":"Galectin-3 predicts short- and long-term outcome in patients undergoing transcatheter aortic valve implantation (TAVI)","volume":"177","author":"Baldenhofer","year":"2014","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0060","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s00392-010-0125-y","article-title":"Prognostic value of galectin-3, a novel marker of fibrosis, in patients with chronic heart failure: data from the DEAL-HF study","volume":"99","author":"Lok","year":"2010","journal-title":"Clin. Res. Cardiol."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0065","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/j.jacc.2006.03.061","article-title":"Utility of amino-terminal pro-brain natriuretic peptide, galectin-3, and apelin for the evaluation of patients with acute heart failure","volume":"48","author":"van Kimmenade","year":"2006","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0070","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/ejechocard\/jeq031","article-title":"European Association of Echocardiography recommendations for the assessment of valvular regurgitation. Part 2: mitral and tricuspid regurgitation (native valve disease)","volume":"11","author":"Lancellotti","year":"2010","journal-title":"Eur. J. Echocardiogr."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0075","doi-asserted-by":"crossref","first-page":"71","DOI":"10.7863\/jum.2011.30.1.71","article-title":"Speckle-tracking echocardiography: a new technique for assessing myocardial function","volume":"30","author":"Mondillo","year":"2011","journal-title":"J. Ultrasound Med."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0080","author":"Dhand"},{"key":"10.1016\/j.ijcard.2018.04.025_bb0085","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0168349","article-title":"Prediction of left ventricular remodeling after a myocardial infarction: role of myocardial deformation: a systematic review and meta-analysis","volume":"11","author":"Huttin","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.ijcard.2018.04.025_bb0090","doi-asserted-by":"crossref","first-page":"669","DOI":"10.2459\/JCM.0000000000000526","article-title":"Global longitudinal strain predicts outcome after MitraClip implantation for secondary mitral regurgitation","volume":"18","author":"Citro","year":"2017","journal-title":"J. Cardiovasc. Med. (Hagerstown)"},{"issue":"5","key":"10.1016\/j.ijcard.2018.04.025_bb0095","doi-asserted-by":"crossref","first-page":"4983","DOI":"10.1016\/j.ijcard.2013.07.132","article-title":"Reverse left ventricular remodeling after percutaneous mitral valve repair: strain analysis by speckle tracking echocardiography and cardiac magnetic resonance imaging","volume":"168","author":"Zuern","year":"2013","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0100","doi-asserted-by":"crossref","first-page":"2844","DOI":"10.1016\/j.jacc.2015.10.018","article-title":"Randomized comparison of percutaneous repair and surgery for mitral regurgitation: 5-year results of EVEREST II","volume":"66","author":"Feldman","year":"2015","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0105","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1007\/s00392-015-0872-x","article-title":"Influence of non-cardiac comorbidities on outcome after percutaneous mitral valve repair: results from the German transcatheter mitral valve interventions (TRAMI) registry","volume":"104","author":"Zuern","year":"2015","journal-title":"Clin. Res. Cardiol."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0110","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s00392-014-0670-x","article-title":"Cardiac magnetic resonance imaging in patients undergoing percutaneous mitral valve repair with the MitraClip system","volume":"103","author":"Krumm","year":"2014","journal-title":"Clin. Res. Cardiol."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0115","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.ahj.2015.08.004","article-title":"The MitraClip and survival in patients with mitral regurgitation at high risk for surgery: a propensity-matched comparison","volume":"170","author":"Velazquez","year":"2015","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0120","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1007\/s00392-011-0324-1","article-title":"Percutaneous mitral valve repair using the MitraClip in acute cardiogenic shock","volume":"100","author":"Zuern","year":"2011","journal-title":"Clin. Res. Cardiol."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0125","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0735-1097(99)00630-0","article-title":"Cardiac remodeling\u2014concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling","volume":"35","author":"Cohn","year":"2000","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0130","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1378\/chest.105.3.897","article-title":"Basic mechanisms in congestive heart failure. Recognizing the role of proinflammatory cytokines","volume":"105","author":"Mann","year":"1994","journal-title":"Chest"},{"key":"10.1016\/j.ijcard.2018.04.025_bb0135","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1093\/eurjhf\/hfq091","article-title":"Galectin-3, cardiac structure and function, and long-term mortality in patients with acutely decompensated heart failure","volume":"12","author":"Shah","year":"2010","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0140","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1530\/ERP-16-0022","article-title":"Global longitudinal strain: a useful everyday measurement?","volume":"3","author":"King","year":"2016","journal-title":"Echo Res. Pract."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0145","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1681\/ASN.2014010093","article-title":"Galectin-3, renal function, and clinical outcomes: results from the LURIC and 4D studies","volume":"26","author":"Drechsler","year":"2015","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0150","first-page":"502","article-title":"Reverse cardiac remodeling: a marker of better prognosis in heart failure","volume":"104","author":"Reis Filho","year":"2015","journal-title":"Arq. Bras. Cardiol."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0155","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1177\/107424849800300403","article-title":"Effect of digoxin on ventricular remodeling and responsiveness of beta-adrenoceptors in chronic volume overload","volume":"3","author":"Sullebarger","year":"1998","journal-title":"J. Cardiovasc. Pharmacol. Ther."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0160","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.amjcard.2011.03.056","article-title":"Usefulness of plasma galectin-3 levels in systolic heart failure to predict renal insufficiency and survival","volume":"108","author":"Tang","year":"2011","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0165","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1161\/CIRCHEARTFAILURE.111.963637","article-title":"Galectin-3 in ambulatory patients with heart failure: results from the HF-ACTION study","volume":"5","author":"Felker","year":"2012","journal-title":"Circ. Heart Fail."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0170","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.ahj.2014.02.009","article-title":"Galectin 3 and incident atrial fibrillation in the community","volume":"167","author":"Ho","year":"2014","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ijcard.2018.04.025_bb0175","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0137464","article-title":"Midregional-proatrial natriuretic peptide and high sensitive troponin T strongly predict adverse outcome in patients undergoing percutaneous repair of mitral valve regurgitation","volume":"10","author":"Wohrle","year":"2015","journal-title":"PLoS One"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527317371541?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527317371541?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T16:55:17Z","timestamp":1534956917000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527317371541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":35,"alternative-id":["S0167527317371541"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2018.04.025","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Galectin-3 is associated with left ventricular reverse remodeling and outcome after percutaneous mitral valve repair","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2018.04.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}