{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T11:25:07Z","timestamp":1778844307692,"version":"3.51.4"},"reference-count":10,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.ijcard.2019.05.004","type":"journal-article","created":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T11:50:20Z","timestamp":1558439420000},"page":"140-141","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Role of adenosine in the treatment of cardiovascular diseases: Focus on hyperemia"],"prefix":"10.1016","volume":"291","author":[{"given":"Aleksandro S.","family":"Da Silva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matheus D.","family":"Baldissera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carine F.","family":"Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2019.05.004_bb0005","doi-asserted-by":"crossref","first-page":"30","DOI":"10.3390\/brainsci7030030","article-title":"The role of adenosine signaling in headache: a review","volume":"7","author":"Fried","year":"2017","journal-title":"Brain Sci."},{"key":"10.1016\/j.ijcard.2019.05.004_bb0010","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1161\/01.CIR.82.5.1595","article-title":"Effects of adenosine on human coronary arterial circulation","volume":"82","author":"Wilson","year":"1990","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2019.05.004_bb0015","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.jcin.2014.02.009","article-title":"Adenosine: physiology, pharmacology, and clinical applications","volume":"7","author":"Layland","year":"2014","journal-title":"JACC Cardiovasc. Interv."},{"key":"10.1016\/j.ijcard.2019.05.004_bb0020","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1002\/jcp.27161","article-title":"Therapeutic potential of A2 adenosine receptor pharmacological regulators in the treatment of cardiovascular diseases, recent progress, and prospective","volume":"234","author":"Bahreyni","year":"2019","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.ijcard.2019.05.004_bb0025","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/S1734-1140(11)70573-4","article-title":"Therapeutic potential of adenosine analogues and conjugates","volume":"63","author":"Samsel","year":"2011","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.ijcard.2019.05.004_bb0030","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.ijcard.2018.09.088","article-title":"Impact of increasing dose of intracoronary adenosine on peak hyperemia duration during fractional flow reserve assessment","volume":"284","author":"Verdoia","year":"2019","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2019.05.004_bb0035","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0304-3940(02)00290-2","article-title":"The involvement of nitric oxide on the adenosine A2 receptor-induced cardiovascular inhibitory responses in the posterior hypothalamus of rats","volume":"326","author":"Song","year":"2002","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ijcard.2019.05.004_bb0040","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0304-3940(00)01486-5","article-title":"Modification of cardiovascular response of adenosine A2 receptor agonist by adenylate cyclase in the spinal cord of rats","volume":"293","author":"Koh","year":"2000","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ijcard.2019.05.004_bb0045","first-page":"R152","article-title":"Fetal cardiovascular and breathing responses to an adenosine A2a receptor agonist in sheep","volume":"274","author":"Koos","year":"1998","journal-title":"Am. J. Phys. Regul. Integr. Comp. Phys."},{"key":"10.1016\/j.ijcard.2019.05.004_bb0050","doi-asserted-by":"crossref","first-page":"H83","DOI":"10.1152\/ajpheart.2001.280.1.H83","article-title":"Adenosine A2A receptors mediate cardiovascular responses to hypoxia in fetal sheep","volume":"280","author":"Koos","year":"2001","journal-title":"Am. J. Physiol. Heart Circ. Physiol."}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527319305546?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527319305546?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T20:42:58Z","timestamp":1759092178000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527319305546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":10,"alternative-id":["S0167527319305546"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2019.05.004","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of adenosine in the treatment of cardiovascular diseases: Focus on hyperemia","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2019.05.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2018.09.088","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}