{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T17:10:31Z","timestamp":1784740231094,"version":"3.55.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.ijcard.2019.09.034","type":"journal-article","created":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T22:47:19Z","timestamp":1572648439000},"page":"173-179","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["Effects of acute exposure to moderate altitude on blood pressure and sleep breathing patterns"],"prefix":"10.1016","volume":"301","author":[{"given":"Camilla","family":"Torlasco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grzegorz","family":"Bilo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Giuliano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Soranna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Ravaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Oliverio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Faini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Zambon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Lombardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianfranco","family":"Parati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"17","key":"10.1016\/j.ijcard.2019.09.034_bb0005","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1093\/eurheartj\/ehx720","article-title":"Clinical recommendations for high altitude exposure of individuals with pre-existing cardiovascular conditions","volume":"39","author":"Parati","year":"2018","journal-title":"Eur. Heart J."},{"issue":"19","key":"10.1016\/j.ijcard.2019.09.034_bb0010","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1161\/CIRCULATIONAHA.106.650796","article-title":"Effect of altitude on the heart and the lungs","volume":"116","author":"Bartsch","year":"2007","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.ijcard.2019.09.034_bb0015","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/imammb\/19.4.293","article-title":"Periodic breathing at high altitude","volume":"19","author":"Fowler","year":"2002","journal-title":"IMA J. Math. Appl. Med. Biol."},{"issue":"23","key":"10.1016\/j.ijcard.2019.09.034_bb0020","doi-asserted-by":"crossref","first-page":"4837","DOI":"10.1113\/jphysiol.2010.194704","article-title":"High-altitude pulmonary hypertension is associated with a free radical-mediated reduction in pulmonary nitric oxide bioavailability: redox regulation of hypoxic pulmonary vasoconstriction","volume":"588","author":"Bailey","year":"2010","journal-title":"J. Physiol."},{"issue":"9","key":"10.1016\/j.ijcard.2019.09.034_bb0025","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1161\/CIRCULATIONAHA.106.624544","article-title":"The heart and pulmonary circulation at high altitudes: healthy highlanders and chronic mountain sickness","volume":"115","author":"Penaloza","year":"2007","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.ijcard.2019.09.034_bb0030","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1152\/japplphysiol.01167.2010","article-title":"High-altitude exposure of three weeks duration increases lung diffusing capacity in humans","volume":"110","author":"Agostoni","year":"2011","journal-title":"J. Appl. Physiol."},{"issue":"2","key":"10.1016\/j.ijcard.2019.09.034_bb0035","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1089\/ham.2012.1117","article-title":"Considerations on safety and treatment of patients with chronic heart failure at high altitude","volume":"14","author":"Agostoni","year":"2013","journal-title":"High Alt. Med. Biol."},{"issue":"2","key":"10.1016\/j.ijcard.2019.09.034_bb0040","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1159\/000492898","article-title":"Right and left heart function in lowlanders with COPD at altitude: data from a randomized study","volume":"97","author":"Lichtblau","year":"2019","journal-title":"Respiration."},{"key":"10.1016\/j.ijcard.2019.09.034_bb0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-0838.2008.00827.x","article-title":"General introduction to altitude adaptation and mountain sickness: altitude adaptation and mountain sickness","volume":"18","author":"B\u00e4rtsch","year":"2008","journal-title":"Scand. J. Med. Sci. Sports"},{"issue":"1","key":"10.1016\/j.ijcard.2019.09.034_bb0050","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1089\/ham.2017.0164","article-title":"The 2018 Lake Louise Acute Mountain Sickness Score","volume":"19","author":"Roach","year":"2018","journal-title":"High Alt. Med. Biol."},{"issue":"5","key":"10.1016\/j.ijcard.2019.09.034_bb0055","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1097\/00004872-199605000-00003","article-title":"Prediction of the actual awake and asleep blood pressures by various methods of 24 h pressure analysis","volume":"14","author":"Fagard","year":"1996","journal-title":"J. Hypertens."},{"issue":"5","key":"10.1016\/j.ijcard.2019.09.034_bb0060","doi-asserted-by":"crossref","first-page":"597","DOI":"10.5664\/jcsm.2172","article-title":"Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events","volume":"8","author":"Berry","year":"2012","journal-title":"J. Clin. Sleep Med."},{"key":"10.1016\/j.ijcard.2019.09.034_bb0065","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"JR Statistic Soc."},{"issue":"1","key":"10.1016\/j.ijcard.2019.09.034_bb0070","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1378\/chest.14-0317","article-title":"Sex and acetazolamide effects on chemoreflex and periodic breathing during sleep at altitude","volume":"147","author":"Caravita","year":"2015","journal-title":"Chest"},{"issue":"12","key":"10.1016\/j.ijcard.2019.09.034_bb0075","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.5665\/sleep.3242","article-title":"Are nocturnal breathing, sleep, and cognitive performance impaired at moderate altitude (1,630\u20132,590 m)?","volume":"36","author":"Latshang","year":"2013","journal-title":"Sleep."},{"issue":"44","key":"10.1016\/j.ijcard.2019.09.034_bb0080","doi-asserted-by":"crossref","first-page":"3113","DOI":"10.1093\/eurheartj\/ehu275","article-title":"Changes in 24 h ambulatory blood pressure and effects of angiotensin II receptor blockade during acute and prolonged high-altitude exposure: a randomized clinical trial","volume":"35","author":"Parati","year":"2014","journal-title":"Eur. Heart J."},{"issue":"3","key":"10.1016\/j.ijcard.2019.09.034_bb0085","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/BF02281624","article-title":"The effects of exposure to moderate altitude on cardiovascular autonomic function in normal subjects","volume":"9","author":"Veglio","year":"1999","journal-title":"Clin. Auton. Res."},{"issue":"8","key":"10.1016\/j.ijcard.2019.09.034_bb0090","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0070081","article-title":"Effects of acute exposure to moderate altitude on vascular function, metabolism and systemic inflammation","volume":"8","author":"St\u00f6whas","year":"2013","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.ijcard.2019.09.034_bb0095","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1161\/HYPERTENSIONAHA.114.05003","article-title":"Ambulatory blood pressure in untreated and treated hypertensive patients at high altitude novelty and significance: the high altitude cardiovascular research\u2013Andes study","volume":"65","author":"Bilo","year":"2015","journal-title":"Hypertension"},{"key":"10.1016\/j.ijcard.2019.09.034_bb0100","doi-asserted-by":"crossref","first-page":"659","DOI":"10.2147\/COPD.S194426","article-title":"Blood pressure response to exposure to moderate altitude in patients with COPD","volume":"14","author":"Schwarz","year":"2019","journal-title":"Int. J. Chron. Obstruct. Pulmon. Dis."},{"key":"10.1016\/j.ijcard.2019.09.034_bb0105","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.ijcard.2016.09.094","article-title":"Role of acetazolamide and telmisartan\/nifedipine-GITS combination in antagonizing the blood pressure rise induced by high altitude exposure","volume":"225","author":"Caravita","year":"2016","journal-title":"Int. J. Cardiol."},{"issue":"8","key":"10.1016\/j.ijcard.2019.09.034_bb0110","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1253\/circj.CJ-09-0004","article-title":"Autonomic and cardiovascular effects of acute high altitude exposure after myocardial infarction and in normal volunteers","volume":"73","author":"Messerli-Burgy","year":"2009","journal-title":"Circ. J."},{"issue":"1","key":"10.1016\/j.ijcard.2019.09.034_bb0115","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0006-8993(82)90478-4","article-title":"Adaptive response of carotid body chemoreceptors to CO2","volume":"234","author":"Lahiri","year":"1982","journal-title":"Brain Res."},{"issue":"3","key":"10.1016\/j.ijcard.2019.09.034_bb0120","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1161\/01.CIR.61.3.463","article-title":"Circulatory adjustments to hypoxia","volume":"61","author":"Heistad","year":"1980","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.ijcard.2019.09.034_bb0125","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1152\/jappl.1987.63.2.531","article-title":"Operation Everest II: preservation of cardiac function at extreme altitude","volume":"63","author":"Reeves","year":"1987","journal-title":"J. Appl. Physiol."},{"issue":"2","key":"10.1016\/j.ijcard.2019.09.034_bb0130","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1089\/ham.2015.0010","article-title":"Aging, high altitude, and blood pressure: a complex relationship","volume":"16","author":"Parati","year":"2015","journal-title":"High Alt. Med. Biol."},{"issue":"1","key":"10.1016\/j.ijcard.2019.09.034_bb0135","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1161\/HYPERTENSIONAHA.117.09197","article-title":"Renin-angiotensin-aldosterone system is not involved in the arterial stiffening induced by acute and prolonged exposure to high altitude","volume":"70","author":"Revera","year":"2017","journal-title":"Hypertension"},{"issue":"3","key":"10.1016\/j.ijcard.2019.09.034_bb0140","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1111\/jsr.12012","article-title":"High-altitude hypoxia and periodic breathing during sleep: gender-related differences","volume":"22","author":"Lombardi","year":"2013","journal-title":"J. Sleep Res."},{"issue":"10","key":"10.1016\/j.ijcard.2019.09.034_bb0145","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1016\/S1357-2725(03)00050-5","article-title":"CO2\/H(+) sensing: peripheral and central chemoreception","volume":"35","author":"Lahiri","year":"2003","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"3","key":"10.1016\/j.ijcard.2019.09.034_bb0150","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.resp.2010.02.015","article-title":"An interdependent model of central\/peripheral chemoreception: evidence and implications for ventilatory control","volume":"173","author":"Smith","year":"2010","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.ijcard.2019.09.034_bb0155","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-0-387-75434-5_1","article-title":"Risk of cardiovascular events during mountain activities","volume":"618","author":"Burtscher","year":"2007","journal-title":"Adv. Exp. Med. Biol."}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527319316468?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527319316468?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T20:46:26Z","timestamp":1759092386000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527319316468"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":31,"alternative-id":["S0167527319316468"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2019.09.034","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of acute exposure to moderate altitude on blood pressure and sleep breathing patterns","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2019.09.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}