{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T09:41:41Z","timestamp":1766137301907,"version":"3.44.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,1,10]],"date-time":"2021-01-10T00:00:00Z","timestamp":1610236800000},"content-version":"am","delay-in-days":344,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.ijcard.2019.10.032","type":"journal-article","created":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T12:22:54Z","timestamp":1571660574000},"page":"121-126","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Cardiac performance assessment during cardiopulmonary exercise test can improve the management of children with repaired congenital heart disease"],"prefix":"10.1016","volume":"300","author":[{"given":"L.","family":"Guirgis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Khraiche","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ladouceur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Iserin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Bonnet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Legendre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2019.10.032_bib1","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1161\/CIRCULATIONAHA.104.529800","article-title":"Exercise intolerance in adult congenital heart disease: comparative severity, correlates, and prognostic implication","volume":"112","author":"Diller","year":"2005","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.ijcard.2019.10.032_bib2","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1161\/01.CIR.92.1.47","article-title":"Dissociation between exertional symptoms and circulatory function in patients with heart failure","volume":"92","author":"Wilson","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2019.10.032_bib3","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1016\/j.amjcard.2007.06.038","article-title":"Cardiac magnetic resonance imaging correlates of exercise capacity in patients with surgically repaired tetralogy of Fallot","volume":"100","author":"Meadows","year":"2007","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib4","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1136\/heartjnl-2012-302147","article-title":"Exercise capacity and stroke volume are preserved late after tetralogy repair, despite severe right ventricular dilatation","volume":"98","author":"O'Meagher","year":"2012","journal-title":"Heart"},{"key":"10.1016\/j.ijcard.2019.10.032_bib5","doi-asserted-by":"crossref","first-page":"151","DOI":"10.4103\/0974-2069.99617","article-title":"Effect of ventricular size and function on exercise performance and the electrocardiogram in repaired tetralogy of Fallot with pure pulmonary regurgitation","volume":"5","author":"Menon","year":"2012","journal-title":"Ann. Pediatr. Cardiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib6","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ijcard.2015.04.285","article-title":"Hemodynamic, not ventilatory, inefficiency is associated with high VE\/VCO2 slope in repaired, noncyanotic congenital heart disease","volume":"191","author":"Mezzani","year":"2015","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib7","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0167-5273(95)02551-0","article-title":"Contribution of cardiopulmonary indices in the assessment of patients with silent and symptomatic ischemia during exercise testing","volume":"53","author":"Klainman","year":"1996","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib8","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.amjcard.2003.10.011","article-title":"Differential contribution of dead space ventilation and low arterial pCO2 to exercise hyperpnea in patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy","volume":"93","author":"Wensel","year":"2004","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib9","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1152\/jappl.2000.88.2.560","article-title":"Structural basis of muscle O(2) diffusing capacity: evidence from muscle function in situ","volume":"88","author":"Hepple","year":"2000","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib10","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1249\/00005768-199501000-00010","article-title":"Muscle O2 transport and O2 dependent control of metabolism","volume":"27","author":"Wagner","year":"1995","journal-title":"Med. Sci. Sport. Exerc."},{"key":"10.1016\/j.ijcard.2019.10.032_bib11","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1152\/jappl.1992.73.3.1067","article-title":"Effects of training on muscle O2 transport at VO2max","volume":"73","author":"Roca","year":"1992","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib12","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/apha.12258","article-title":"Low-intensity training increases peak arm VO2 by enhancing both convective and diffusive O2 delivery","volume":"211","author":"Boushel","year":"2014","journal-title":"Acta Physiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib13","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1016\/j.jacc.2009.11.086","article-title":"Limited maximal exercise capacity in patients with chronic heart failure: partitioning the contributors","volume":"55","author":"Esposito","year":"2010","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib14","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1007\/BF02238841","article-title":"Postoperative exercise training develops normal levels of physical activity in a group of children following cardiac surgery","volume":"11","author":"Longmuir","year":"1990","journal-title":"Pediatr. Cardiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib15","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0002-9149(99)00640-2","article-title":"Homograft insertion for pulmonary regurgitation after repair of tetralogy of fallot improves cardiorespiratory exercise performance","volume":"85","author":"Eyskens","year":"2000","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib16","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s00246-017-1725-3","article-title":"Reliability of peak exercise stroke volume Assessment by impedance cardiography in patients with residual right outflow tract lesions after congenital heart disease repair","volume":"39","author":"Legendre","year":"2018","journal-title":"Pediatr. Cardiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib17","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.1152\/jappl.1986.60.6.2020","article-title":"A new method for detecting anaerobic threshold by gas exchange","volume":"60","author":"Beaver","year":"1986","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib18","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1253\/jcj.61.488","article-title":"Clinical application of cardiac output during ramp exercise calculated using the Fick equation-comparison with the 2-stage bicycle ergometer exercise protocol in the supine position","volume":"6","author":"Yamabe","year":"1997","journal-title":"Jpn. Circ. J."},{"key":"10.1016\/j.ijcard.2019.10.032_bib19","first-page":"599","article-title":"Simple, accurate equations for human blood O2 dissociation computations","volume":"46","author":"Severinghaus","year":"1979","journal-title":"J. Appl. Physiol. Respir. Environ. Exerc. Physiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib20","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1097\/MPH.0000000000001115","article-title":"Anemia in adolescents and young adult patients with congenital heart disease","volume":"40","author":"Rodr\u00edguez-Hern\u00e1ndez","year":"2018","journal-title":"J. Pediatr. Hematol. Oncol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib21","first-page":"H789","article-title":"O2 gradients from sarcolemma to cell interior in red muscle at maximal VO2","volume":"251","author":"Gayeski","year":"1986","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib22","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1152\/jappl.1989.67.1.291","article-title":"Evidence for tissue diffusion limitation of VO2max in normal humans","volume":"67","author":"Roca","year":"1989","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib23","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.jchf.2014.11.011","article-title":"Cardiopulmonary responses and prognosis in hypertrophic cardiomyopathy: a potential role for comprehensive noninvasive hemodynamic assessment","volume":"3","author":"Finocchiaro","year":"2015","journal-title":"JACC Heart Fail"},{"key":"10.1016\/j.ijcard.2019.10.032_bib24","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1161\/01.CIR.0000101681.27911.FA","article-title":"Stratification of pediatric heart failure on the basis of neurohormonal and cardiac autonomic nervous activities in patients with congenital heart disease","volume":"108","author":"Ohuchi","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2019.10.032_bib25","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/0002-9149(80)90170-8","article-title":"Radionuclide assessment of right and left ventricular exercise reserve after total correction of tetralogy of Fallot","volume":"45","author":"Reduto","year":"1980","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib26","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1148\/radiol.2261011164","article-title":"Tetralogy of Fallot: postoperative delayed recovery of left ventricular stroke volume after physical exercise assessment with fast MR imaging","volume":"226","author":"Roest","year":"2003","journal-title":"Radiology"},{"issue":"1","key":"10.1016\/j.ijcard.2019.10.032_bib27","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.echo.2018.08.008","article-title":"Right ventricular contractile reserve is impaired in children and adolescents with repaired tetralogy of fallot: an exercise strain imaging study","volume":"32","author":"Bhatt","year":"2019","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"10.1016\/j.ijcard.2019.10.032_bib28","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1097\/HJR.0b013e32808621b9","article-title":"Physical activity levels in adults with congenital heart disease","volume":"14","author":"Dua","year":"2007","journal-title":"Eur. J. Cardiovasc. Prev. Rehabil."},{"key":"10.1016\/j.ijcard.2019.10.032_bib29","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1136\/adc.2006.105239","article-title":"Physical activity levels in children and adolescents are reduced after the Fontan procedure, independent of exercise capacity, and are associated with lower perceived general health","volume":"92","author":"McCrindle","year":"2007","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.ijcard.2019.10.032_bib30","doi-asserted-by":"crossref","first-page":"e143","DOI":"10.1016\/j.jacc.2008.10.001","volume":"52","author":"Warnes","year":"2008","journal-title":"J. Am. Coll. Cardiol."},{"issue":"13","key":"10.1016\/j.ijcard.2019.10.032_bib31","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.jacc.2011.06.025","article-title":"Isolated quadriceps training increases maximal exercise capacity in chronic heart failure: the role of skeletal muscle convective and diffusive oxygen transport","volume":"58","author":"Esposito","year":"2011","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib32","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s004210000226","article-title":"A new impedance cardiograph device for the non-invasive evaluation of cardiac output at rest and during exercise: comparison with the \"direct\" Fick method","volume":"82","author":"Charloux","year":"2000","journal-title":"Eur. J. Appl. Physiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib33","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1007\/s004210100458","article-title":"Non-invasive cardiac output evaluation during a maximal progressive exercise test, using a new impedance cardiograph device","volume":"85","author":"Richard","year":"2001","journal-title":"Eur. J. Appl. Physiol."},{"issue":"1","key":"10.1016\/j.ijcard.2019.10.032_bib34","doi-asserted-by":"crossref","first-page":"e20","DOI":"10.1111\/sms.12201","article-title":"Cardiac output during exercise: a comparison of four methods","volume":"25","author":"Siebenmann","year":"2015","journal-title":"Scand. J. Med. Sci. Sport."},{"key":"10.1016\/j.ijcard.2019.10.032_bib35","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s00408-011-9299-y","article-title":"Value of impedance cardiography in patients studied for pulmonary hypertension","volume":"189","author":"Tonelli","year":"2011","journal-title":"Lung"},{"issue":"4","key":"10.1016\/j.ijcard.2019.10.032_bib36","first-page":"1122","article-title":"Does thoracic bioimpedance accurately determine cardiac output in COPD patients during maximal or intermittent exercise?","volume":"127","author":"Bougault","year":"2005","journal-title":"Chest"},{"issue":"4","key":"10.1016\/j.ijcard.2019.10.032_bib37","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1111\/crj.13002","article-title":"Cardiac output measurement during exercise in COPD: a comparison of dye dilution and impedance cardiography","volume":"13","author":"Louvaris","year":"2019","journal-title":"Clin. Res. J"},{"key":"10.1016\/j.ijcard.2019.10.032_bib38","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1152\/japplphysiol.90430.2008","article-title":"Evaluation of two methods for continuous cardiac output assessment during exercise in chronic heart failure patients","volume":"105","author":"Kemps","year":"1985","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib39","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1007\/s00421-004-1300-5","article-title":"Reliability of peak VO(2) and maximal cardiac output assessed using thoracic bioimpedance in children","volume":"94","author":"Welsman","year":"2005","journal-title":"Eur. J. Appl. Physiol."},{"key":"10.1016\/j.ijcard.2019.10.032_bib40","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1161\/01.CIR.100.10.1085","article-title":"Aerobic exercise training can reverse age-related peripheral circulatory changes in healthy older men","volume":"100","author":"Beere","year":"1999","journal-title":"Circulation"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527319336034?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527319336034?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T20:46:26Z","timestamp":1759092386000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527319336034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":40,"alternative-id":["S0167527319336034"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2019.10.032","relation":{},"ISSN":["0167-5273"],"issn-type":[{"type":"print","value":"0167-5273"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cardiac performance assessment during cardiopulmonary exercise test can improve the management of children with repaired congenital heart disease","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2019.10.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}