{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T19:16:13Z","timestamp":1790363773153,"version":"4.1.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Italian Ministry of the Education, University and Research"},{"name":"Italian Ministry of Health","award":["NET- 2016-02363853"],"award-info":[{"award-number":["NET- 2016-02363853"]}]},{"name":"European Community"},{"name":"Italian Agency of Drug"},{"DOI":"10.13039\/501100003407","name":"Ministry of Education, University and Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.ijcard.2020.06.017","type":"journal-article","created":{"date-parts":[[2020,6,25]],"date-time":"2020-06-25T11:32:09Z","timestamp":1593084729000},"page":"14-20","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["Better adherence with out-of-hospital healthcare improved long-term prognosis of acute coronary syndromes: Evidence from an Italian real-world investigation"],"prefix":"10.1016","volume":"318","author":[{"given":"Federico","family":"Rea","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaella","family":"Ronco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto F.E.","family":"Pedretti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Merlino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Corrao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2020.06.017_bb0005","doi-asserted-by":"crossref","first-page":"h5153","DOI":"10.1136\/bmj.h5153","article-title":"Acute coronary syndromes","volume":"351","author":"Timmis","year":"2015","journal-title":"BMJ"},{"key":"10.1016\/j.ijcard.2020.06.017_bb0010","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1093\/eurheartj\/ehv320","volume":"37","author":"Roffi","year":"2016","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0015","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/eurheartj\/ehx393","volume":"39","author":"Ibanez","year":"2018","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0020","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1001\/jama.2009.1178","article-title":"Reduction in acute myocardial infarction mortality in the United States: risk-standardized mortality rates from 1995-2006","volume":"302","author":"Krumholz","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.ijcard.2020.06.017_bb0025","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1093\/eurheartj\/ehi511","article-title":"Dynamics of cardiovascular and all-cause mortality in Western and Eastern Europe between 1970 and 2002","volume":"27","author":"Kesteloot","year":"2006","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0030","first-page":"651","article-title":"Gruppo di Ricerca MONICA-CAMUNI in Brianza. [Recent time trends of myocardial infarction rates in northern Italy. Results from the MONICA and CAMUNI registries in Brianza: 1993-1994 versus 1997-1998]","volume":"4","author":"Ferrario","year":"2003","journal-title":"Ital Heart J. Suppl."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0035","first-page":"161","article-title":"Incidence of acute myocardial infarction in Tuscany, 1997-2002: data from the acute myocardial infarction registry of Tuscany (Tosc-AMI)","volume":"30","author":"Barchielli","year":"2006","journal-title":"Epidemiol. Prev."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0040","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1177\/2047487316679522","article-title":"Trends in long-term prognosis after acute coronary syndrome","volume":"24","author":"Piironen","year":"2017","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0045","doi-asserted-by":"crossref","first-page":"3654","DOI":"10.1093\/eurheartj\/ehy420","article-title":"Early cardiovascular protection by initial two-drug fixed-dose combination treatment vs. monotherapy in hypertension","volume":"39","author":"Rea","year":"2018","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0050","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.ejim.2017.09.023","article-title":"Good adherence to therapy with statins reduces the risk of adverse clinical outcomes even among very elderly. Evidence from an Italian real-life investigation","volume":"47","author":"Corrao","year":"2018","journal-title":"Eur. J. Intern Med."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0055","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.ejim.2014.08.002","article-title":"Are generic and brand-name statins clinically equivalent? Evidence from a real data-base","volume":"25","author":"Corrao","year":"2014","journal-title":"Eur. J. Intern Med."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0060","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2017-019503","article-title":"Developing and validating a novel multisource comorbidity score from administrative data: a large population-based cohort study from Italy","volume":"7","author":"Corrao","year":"2017","journal-title":"BMJ Open"},{"key":"10.1016\/j.ijcard.2020.06.017_bb0065","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1002\/pds.3650","article-title":"BEST investigators. User-only design to assess drug effectiveness in clinical practice: application to bisphosphonates and secondary prevention of fractures","volume":"23","author":"Corrao","year":"2014","journal-title":"Pharmacoepidemiol. Drug Saf."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0070","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.ahj.2010.06.023","article-title":"PACE-MI Investigators. Beta-blocker use following myocardial infarction: low prevalence of evidence-based dosing","volume":"160","author":"Goldberger","year":"2010","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0075","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1002\/pds.1230","article-title":"Methods for evaluation of medical adherence and persistence using automated databases","volume":"15","author":"Andrade","year":"2006","journal-title":"Pharmacoepidemiol. Drug Saf."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0080","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1080\/01621459.1999.10474144","article-title":"A proportional hazards model for the subdistribution of a competing risk","volume":"94","author":"Fine","year":"1999","journal-title":"J. Am. Stat. Assoc."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0085","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2012-002155","article-title":"Differences between acute myocardial infarction and unstable angina: a longitudinal cohort study reporting findings from the Register of Information and knowledge about Swedish Heart Intensive Care Admissions (RIKS-HIA)","volume":"3","author":"Dudas","year":"2013","journal-title":"BMJ Open"},{"key":"10.1016\/j.ijcard.2020.06.017_bb0090","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/joic.12451","volume":"31","author":"Tang","year":"2018","journal-title":"J. Interv. Cardiol."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0095","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1097\/EDE.0b013e3181a663cc","article-title":"High-dimensional propensity score adjustment in studies of treatment effects using health care claims data","volume":"20","author":"Schneeweiss","year":"2009","journal-title":"Epidemiology"},{"key":"10.1016\/j.ijcard.2020.06.017_bb0100","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1093\/aje\/kwr001","article-title":"Covariate selection in high-dimensional propensity score analyses of treatment effects in small samples","volume":"173","author":"Rassen","year":"2011","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0105","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1161\/CIRCULATIONAHA.109.897249","article-title":"Trends in incidence, severity, and outcome of hospitalized myocardial infarction","volume":"121","author":"Roger","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2020.06.017_bb0110","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1161\/CIRCOUTCOMES.111.964700","article-title":"Long-term survival and recurrence after acute myocardial infarction in England, 2004 to 2010","volume":"5","author":"Smolina","year":"2012","journal-title":"Circ. Cardiovasc. Qual. Outcomes"},{"key":"10.1016\/j.ijcard.2020.06.017_bb0115","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.ahj.2015.04.027","article-title":"Trends in mortality and recurrent coronary heart disease events after an acute myocardial infarction among Medicare beneficiaries, 2001-2009","volume":"170","author":"Brown","year":"2015","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0120","doi-asserted-by":"crossref","first-page":"659","DOI":"10.7326\/0003-4819-143-9-200511010-00010","article-title":"Meta-analysis: secondary prevention programs for patients with coronary artery disease","volume":"143","author":"Clark","year":"2005","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0125","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1097\/HJR.0b013e328013f11a","article-title":"Secondary prevention programmes for coronary heart disease: a meta-regression showing the merits of shorter, generalist, primary care-based interventions","volume":"14","author":"Clark","year":"2007","journal-title":"Eur. J. Cardiovasc. Prev. Rehabil."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0130","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/j.hlc.2016.06.789","article-title":"NHFA\/CSANZ ACS guideline 2016 executive working group:. national heart foundation of Australia & cardiac society of Australia and New Zealand: Australian clinical guidelines for the management of acute coronary syndromes 2016","volume":"25","author":"Chew","year":"2016","journal-title":"Heart Lung Circ."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0135","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1177\/2047487312449597","volume":"21","author":"Piepoli","year":"2014","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0140","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.4081\/monaldi.2018.1004","article-title":"Cardiac Prevention and Rehabilitation \u201c3.0\u201d: from acute to chronic phase. Position Paper of the ltalian Association for Cardiovascular Prevention and Rehabilitation (GICR-IACPR)","volume":"88","author":"Pedretti","year":"2018","journal-title":"Monaldi Arch. Chest Dis."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0145","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1177\/0003319718760917","article-title":"For eyeshot study and START antiplatelet register. Epidemiology and management of patients with acute coronary syndromes in contemporary real-world practice: evolving trends from the Eyeshot study to the start-antiplatelet registry","volume":"69","author":"Calabr\u00f2","year":"2018","journal-title":"Angiology"},{"key":"10.1016\/j.ijcard.2020.06.017_bb0150","doi-asserted-by":"crossref","first-page":"3110","DOI":"10.1161\/CIRCULATIONAHA.108.799981","article-title":"Long-term mortality of patients undergoing cardiac catheterization for ST-elevation and non-ST-elevation myocardial infarction","volume":"119","author":"Chan","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2020.06.017_bb0155","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1161\/CIRCOUTCOMES.115.002312","article-title":"Differences in short- and long-term outcomes among older patients with ST-elevation versus non-ST-elevation myocardial infarction with angiographically proven coronary artery disease","volume":"9","author":"Vora","year":"2016","journal-title":"Circ. Cardiovasc. Qual. Outcomes"},{"key":"10.1016\/j.ijcard.2020.06.017_bb0160","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1016\/j.amjmed.2017.05.037","article-title":"Unstable angina in the era of cardiac troponin assays with improved sensitivity-a clinical dilemma","volume":"130","author":"Eggers","year":"2017","journal-title":"Am. J. Med."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0165","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1177\/2047487319833512","article-title":"Impact of in-hospital cardiac rehabilitation on mortality and readmissions in heart failure: a population study in Lombardy, Italy, from 2005 to 2012","volume":"26","author":"Scalvini","year":"2019","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0170","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1177\/2047487319840724","article-title":"Cardiac rehabilitation in Europe: where we are and where we are going","volume":"26","author":"Pedretti","year":"2019","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0175","article-title":"Although cardiac rehab saves lives, Few eligible patients take part","author":"Rubin","year":"2019","journal-title":"JAMA"},{"issue":"4 Suppl 2","key":"10.1016\/j.ijcard.2020.06.017_bb0180","first-page":"37","article-title":"A systematic review of case-identification algorithms based on Italian healthcare administrative databases for three relevant diseases of the cardiovascular system: acute myocardial infarction, ischemic heart disease, and stroke","volume":"43","author":"Hyeraci","year":"2019","journal-title":"Epidemiol. Prev."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0185","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jval.2011.08.005","article-title":"Quantifying the impact of drug exposure misclassification due to restrictive drug coverage in administrative databases: a simulation cohort study","volume":"15","author":"Gamble","year":"2012","journal-title":"Value Health"},{"key":"10.1016\/j.ijcard.2020.06.017_bb0190","first-page":"741","article-title":"Low-cost generic program use by medicare beneficiaries: implications for medication exposure misclassification in administrative claims data","volume":"22","author":"Pauly","year":"2016","journal-title":"J. Manag. Care Spec. Pharm."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0195","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s40471-014-0027-z","article-title":"Misclassification in administrative claims data: quantifying the impact on treatment effect estimates","volume":"1","author":"Funk","year":"2014","journal-title":"Curr. Epidemiol. Rep."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0200","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.jclinepi.2014.12.001","article-title":"Tutorial: strategies addressing detection bias were reviewed and implemented for investigating the statins-diabetes association","volume":"68","author":"Arf\u00e8","year":"2015","journal-title":"J. Clin. Epidemiol."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0205","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1001\/archinternmed.2009.324","article-title":"The healthy adherer effect","volume":"169","author":"Andersohn","year":"2009","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.ijcard.2020.06.017_bb0210","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/jep.12095","article-title":"Healthy adherer effect - the pitfall in the interpretation of the effect of medication adherence on health outcomes","volume":"20","author":"Ladova","year":"2014","journal-title":"J. Eval. Clin. Pract."}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527320333957?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527320333957?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T20:49:11Z","timestamp":1759092551000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527320333957"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":42,"alternative-id":["S0167527320333957"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2020.06.017","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Better adherence with out-of-hospital healthcare improved long-term prognosis of acute coronary syndromes: Evidence from an Italian real-world investigation","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2020.06.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}