{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T07:02:20Z","timestamp":1763535740861,"version":"3.44.0"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.ijcard.2020.08.046","type":"journal-article","created":{"date-parts":[[2020,8,16]],"date-time":"2020-08-16T17:30:34Z","timestamp":1597599034000},"page":"258-264","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Temporal trends of atrial fibrillation and\/or rheumatic heart disease-related ischemic stroke, and anticoagulant use in Chinese population: An 8-year study"],"prefix":"10.1016","volume":"322","author":[{"given":"Junfeng","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yajun","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shihong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2020.08.046_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/S1474-4422(18)30500-3","article-title":"Stroke in China: advances and challenges in epidemiology, prevention, and management","author":"Wu","year":"2019","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0010","doi-asserted-by":"crossref","DOI":"10.1161\/STROKEAHA.117.020031","article-title":"Distribution and temporal trends from 1993 to 2015 of ischemic stroke subtypes","author":"Ornello","year":"2018","journal-title":"Stroke."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0015","doi-asserted-by":"crossref","DOI":"10.1159\/000323221","article-title":"Characteristics, treatment and outcome of ischemic stroke with atrial fibrillation in a chinese hospital-based stroke study","author":"Lin","year":"2011","journal-title":"Cerebrovasc. Dis."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0020","doi-asserted-by":"crossref","DOI":"10.1161\/STROKEAHA.112.670893","article-title":"Features of acute ischemic stroke with rheumatic heart disease in a hospitalized Chinese population","author":"Wang","year":"2012","journal-title":"Stroke."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0025","article-title":"Stroke associated with atrial fibrillation - incidence and early outcomes in the North Dublin population stroke study","author":"Hannon","year":"2009","journal-title":"Cerebrovasc. Dis."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.ehj.2004.06.030","article-title":"Stroke patients with atrial fibrillation have a worse prognosis than patients without: data from the Austrian stroke registry","author":"Steger","year":"2004","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0035","doi-asserted-by":"crossref","DOI":"10.1097\/HCO.0000000000000365","article-title":"Oral anticoagulation for stroke prevention amongst atrial fibrillation patients with valvular heart disease: an update","author":"Ha","year":"2017","journal-title":"Curr. Opin. Cardiol."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0040","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCULATIONAHA.112.115410","article-title":"Efficacy and safety of the novel oral anticoagulants in atrial fibrillation\u00a0: a systematic review and meta-analysis of the literature","author":"Dentali","year":"2012","journal-title":"Circulation."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0045","doi-asserted-by":"crossref","DOI":"10.7326\/0003-4819-146-12-200706190-00007","article-title":"Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation","author":"Hart","year":"2007","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0050","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD006186","article-title":"Oral anticoagulants versus antiplatelet therapy for preventing stroke in patients with non-valvular atrial brillation and no history of stroke or transient ischemic attacks","author":"Aguilar","year":"2006","journal-title":"Cochrane Database Syst. Rev."},{"issue":"5","key":"10.1016\/j.ijcard.2020.08.046_bb0055","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s00415-014-7297-8","article-title":"Frequency and predictors of spontaneous hemorrhagic transformation in ischemic stroke and its association with prognosis","volume":"261","author":"Tan","year":"2014","journal-title":"J. Neurol."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0060","doi-asserted-by":"crossref","DOI":"10.1159\/000144085","article-title":"Adherence and quality of oral anticoagulation in cerebrovascular disease patients with atrial fibrillation","author":"Weimar","year":"2008","journal-title":"Eur. Neurol."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0065","doi-asserted-by":"crossref","DOI":"10.1136\/jnnp-2017-315735","article-title":"Age-specific trends of atrial fibrillation-related ischaemic stroke and transient ischaemic attack, anticoagulant use and risk factor profile in Chinese population: a 15-year study","author":"Soo","year":"2017","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.ijcard.2020.08.046_bb0070","doi-asserted-by":"crossref","DOI":"10.1161\/STROKEAHA.116.012988","article-title":"Current status and time trends of oral anticoagulation use among Chinese patients with nonvalvular atrial fibrillation: the Chinese atrial fibrillation registry study","author":"Chang","year":"2016","journal-title":"Stroke."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0075","doi-asserted-by":"crossref","DOI":"10.1378\/chest.14-2018","article-title":"Time trends of aspirin and warfarin use on stroke and bleeding events in Chinese patients with new-onset atrial fibrillation","author":"Guo","year":"2015","journal-title":"Chest."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacc.2008.05.042","article-title":"Epidemiology, risk factors for stroke, and Management of Atrial Fibrillation in China","author":"Hu","year":"2008","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.clineuro.2013.06.017","article-title":"Stroke and rheumatic heart disease: a systematic review of observational studies","author":"Wang","year":"2013","journal-title":"Clin. Neurol. Neurosurg."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0090","doi-asserted-by":"crossref","DOI":"10.1179\/1743132815Y.0000000071","article-title":"Antithrombotic therapy for ischaemic stroke patients with AF\/RHD in West China daily practice","author":"Wang","year":"2015","journal-title":"Neurol. Res."},{"issue":"1","key":"10.1016\/j.ijcard.2020.08.046_bb0095","first-page":"113","article-title":"Cerebrovascular disease in the community: results of a WHO collaborative study","volume":"58","author":"Aho","year":"1980","journal-title":"Bull. World Health Organ."},{"year":"2012","series-title":"International Classification of Disease 10 (ICD-10)","author":"World Health Organisation","key":"10.1016\/j.ijcard.2020.08.046_bb0100"},{"key":"10.1016\/j.ijcard.2020.08.046_bb0105","article-title":"Measurements of acute cerebral infarction: a clinical examination scale","author":"Brott","year":"1989","journal-title":"Stroke."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0110","doi-asserted-by":"crossref","DOI":"10.1161\/01.CIR.0000145172.55640.93","article-title":"Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin","author":"Gage","year":"2004","journal-title":"Circulation."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0115","doi-asserted-by":"crossref","DOI":"10.1001\/jama.285.22.2864","article-title":"Validation of clinical classification schemes for predicting stroke: results from the National Registry of atrial fibrillation","author":"Gage","year":"2001","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0120","doi-asserted-by":"crossref","DOI":"10.1378\/chest.09-1584","article-title":"Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the euro heart survey on atrial fibrillation","author":"Lip","year":"2010","journal-title":"Chest."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0125","doi-asserted-by":"crossref","DOI":"10.1186\/s12883-017-0987-y","article-title":"Atrial fibrillation is not uncommon among patients with ischemic stroke and transient ischemic stroke in China","author":"Yang","year":"2017","journal-title":"BMC Neurol."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.jstrokecerebrovasdis.2013.10.006","article-title":"Significant underuse of warfarin in patients with nonvalvular atrial fibrillation: results from the China National Stroke Registry","author":"Wang","year":"2014","journal-title":"J. Stroke Cerebrovasc. Dis."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0135","doi-asserted-by":"crossref","DOI":"10.1111\/j.1747-4949.2011.00716.x","article-title":"Use of oral anticoagulation among stroke patients with atrial fibrillation in China: the ChinaQUEST (quality evaluation of stroke care and treatment) registry study","author":"Gao","year":"2013","journal-title":"Int. J. Stroke"},{"key":"10.1016\/j.ijcard.2020.08.046_bb0140","doi-asserted-by":"crossref","DOI":"10.1161\/STROKEAHA.109.573907","article-title":"Racial disparities in awareness and treatment of atrial fibrillation: the REasons for geographic and racial differences in stroke (REGARDS) study","author":"Meschia","year":"2010","journal-title":"Stroke."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0145","doi-asserted-by":"crossref","DOI":"10.1161\/hs0102.101817","article-title":"Ethnic differences in patient perceptions of atrial fibrillation and anticoagulation therapy: the West Birmingham atrial fibrillation project","author":"Lip","year":"2002","journal-title":"Stroke."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0150","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.116.005128","article-title":"Health literacy and awareness of atrial fibrillation","author":"Reading","year":"2017","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0155","article-title":"Underuse of Oral anticoagulants in patients with ischemic stroke and atrial fibrillation in China","author":"Guo","year":"2018","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0160","article-title":"Five-year epidemiological survey of valvular heart disease: changes in morbidity, etiological spectrum and management in a cardiovascular center of southern China","author":"Liu","year":"2014","journal-title":"J Thorac Dis."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0165","doi-asserted-by":"crossref","DOI":"10.1177\/1747493018772722","article-title":"20-year trends of characteristics and outcomes of stroke patients with atrial fibrillation","author":"Ntaios","year":"2018","journal-title":"Int. J. Stroke"},{"key":"10.1016\/j.ijcard.2020.08.046_bb0170","article-title":"The changing landscape for stroke prevention in AF: findings from the GLORIA-AF registry phase 2","author":"Huisman","year":"2017","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0175","doi-asserted-by":"crossref","DOI":"10.1161\/STROKEAHA.118.023959","article-title":"Disparities and temporal trends in the use of anticoagulation in patients with ischemic stroke and atrial fibrillation","author":"Sur","year":"2019","journal-title":"Stroke."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0180","doi-asserted-by":"crossref","DOI":"10.1007\/s00228-017-2289-0","article-title":"Factors associated with antithrombotic treatment decisions for stroke prevention in atrial fibrillation in the Stockholm region after the introduction of NOACs","author":"Komen","year":"2017","journal-title":"Eur. J. Clin. Pharmacol."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0185","doi-asserted-by":"crossref","DOI":"10.1161\/STROKEAHA.115.009718","article-title":"Socioeconomic inequalities in the prescription of Oral anticoagulants in stroke patients with atrial fibrillation","author":"Sj\u00f6lander","year":"2015","journal-title":"Stroke."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0190","doi-asserted-by":"crossref","DOI":"10.1161\/STROKEAHA.115.009947","article-title":"Non-Vitamin K antagonist oral anticoagulants for stroke prevention in Asian patients with nonvalvular atrial fibrillation: meta-analysis","author":"Wang","year":"2015","journal-title":"Stroke."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0195","article-title":"Does novel oral anticoagulant improve anticoagulation for non-valvular atrial fibrillation associated stroke: An inpatient registration study in Shanghai","author":"Di Liu","year":"2015","journal-title":"Chronic Dis Transl Med."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0200","doi-asserted-by":"crossref","DOI":"10.1136\/heartjnl-2011-300901","article-title":"Risk stratification schemes, anticoagulation use and outcomes: the risk - treatment paradox in patients with newly diagnosed non-valvular atrial fibrillation","author":"Sandhu","year":"2011","journal-title":"Heart."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.ahj.2011.07.019","article-title":"Improvement in use of anticoagulation therapy in patients with ischemic stroke: results from get with the guidelines-stroke","author":"Lewis","year":"2011","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0210","doi-asserted-by":"crossref","DOI":"10.1001\/archinte.160.1.41","article-title":"Why do patients with atrial fibrillation not receive warfarin?","author":"Bungard","year":"2000","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.ijcard.2020.08.046_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacc.2007.01.098","article-title":"Racial\/ethnic differences in the risk of intracranial hemorrhage among patients with atrial fibrillation","author":"Shen","year":"2007","journal-title":"J. Am. Coll. Cardiol."}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527320335737?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527320335737?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T20:49:08Z","timestamp":1759092548000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527320335737"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":43,"alternative-id":["S0167527320335737"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2020.08.046","relation":{},"ISSN":["0167-5273"],"issn-type":[{"type":"print","value":"0167-5273"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Temporal trends of atrial fibrillation and\/or rheumatic heart disease-related ischemic stroke, and anticoagulant use in Chinese population: An 8-year study","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2020.08.046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}