{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T21:10:06Z","timestamp":1759093806826,"version":"3.44.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012679","name":"Institut de Cardiologie de Montr\u00e9al","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012679","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.ijcard.2020.12.089","type":"journal-article","created":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T20:38:40Z","timestamp":1610051920000},"page":"199-205","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["ApoA-I mimetic does not improve left ventricular diastolic dysfunction in rabbits without aortic valve stenosis"],"prefix":"10.1016","volume":"331","author":[{"given":"Walid","family":"Nachar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nolwenn","family":"Merlet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Foued","family":"Maafi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teodora","family":"Mihalache-Avram","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e9lanie","family":"Mecteau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"G\u00e9linas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanfen","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathieu","family":"Brodeur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"Alem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucie","family":"Blondeau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari\u00e8ve","family":"Cossette","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Claude","family":"Guertin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Rhainds","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Busseuil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Rh\u00e9aume","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Claude","family":"Tardif","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2020.12.089_bb0005","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1136\/hrt.2003.029413","article-title":"Assessment of diastolic function: what the general cardiologist needs to know","volume":"91","author":"Mottram","year":"2005","journal-title":"Heart"},{"key":"10.1016\/j.ijcard.2020.12.089_bb0010","first-page":"841","article-title":"Diagnosis and management of diastolic dysfunction and heart failure","volume":"73","author":"Satpathy","year":"2006","journal-title":"Am. Fam. Phys."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0015","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/jhh.2011.113","article-title":"Inflammatory markers are associated with left ventricular hypertrophy and diastolic dysfunction in a population-based sample of elderly men and women","volume":"27","author":"Masiha","year":"2013","journal-title":"J. Hum. Hypertens."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0020","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/S0735-1097(10)80127-5","article-title":"Hypertrophy, fibrosis and diastolic dysfunction in early canine experimental hypertension","volume":"17","author":"Douglas","year":"1991","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0025","doi-asserted-by":"crossref","first-page":"H2341","DOI":"10.1152\/ajpheart.01126.2011","article-title":"Nebivolol improves diastolic dysfunction and myocardial remodeling through reductions in oxidative stress in the transgenic (mRen2) rat","volume":"302","author":"Ma","year":"2012","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0030","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/hr.2011.157","article-title":"Cardiac remodeling and diastolic dysfunction in DahlS.Z-Lepr(fa)\/Lepr(fa) rats: a new animal model of metabolic syndrome","volume":"35","author":"Murase","year":"2012","journal-title":"Hypertens. Res."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0035","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S1098-3597(00)90028-0","article-title":"Diastolic heart failure: diagnosis and treatment","volume":"3","author":"Zile","year":"2000","journal-title":"Clin. Cornerstone"},{"key":"10.1016\/j.ijcard.2020.12.089_bb0040","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/nrcardio.2015.124","article-title":"Dysfunctional HDL and atherosclerotic cardiovascular disease","volume":"13","author":"Rosenson","year":"2016","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0045","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1056\/NEJMoa0706628","article-title":"Effects of torcetrapib in patients at high risk for coronary events","volume":"357","author":"Barter","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0050","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1056\/NEJMoa1300955","article-title":"Effects of extended-release niacin with laropiprant in high-risk patients","volume":"371","author":"Landray","year":"2014","journal-title":"N. Engl. Med."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0055","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1056\/NEJMoa1107579","article-title":"Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy","volume":"365","author":"Aim-High Investigators","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0060","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1093\/eurheartj\/ehx163","article-title":"Extreme high high-density lipoprotein cholesterol is paradoxically associated with high mortality in men and women: two prospective cohort studies","volume":"38","author":"Madsen","year":"2017","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0065","doi-asserted-by":"crossref","first-page":"2693","DOI":"10.1172\/JCI42946","article-title":"Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease","volume":"121","author":"Besler","year":"2011","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0070","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1042\/CS20080106","article-title":"High-density lipoproteins, inflammation and oxidative stress","volume":"116","author":"Tabet","year":"2009","journal-title":"Clin. Sci."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0075","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.3390\/ijms18092012","article-title":"Selective HDL-raising human Apo A-I gene therapy counteracts cardiac hypertrophy, reduces myocardial fibrosis, and improves cardiac function in mice with chronic pressure overload","volume":"18","author":"Amin","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0080","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.115.002681","article-title":"Diastolic left ventricular function in relation to circulating metabolic biomarkers in a general population","volume":"5","author":"Zhang","year":"2016","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0085","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1111\/j.1751-7176.2011.00501.x","article-title":"Influence of low high-density lipoprotein cholesterol on arterial stiffening and left ventricular diastolic dysfunction in essential hypertension","volume":"13","author":"Miao","year":"2011","journal-title":"J. Clin. Hypertens."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0090","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/S0895-7061(03)01015-X","article-title":"Influence of low high-density lipoprotein cholesterol on left ventricular hypertrophy and diastolic function in essential hypertension","volume":"16","author":"Horio","year":"2013","journal-title":"Am. J. Hypertens."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0095","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0046849","article-title":"Lipid lowering and HDL raising gene transfer increase endothelial progenitor cells, enhance myocardial vascularity, and improve diastolic function","volume":"7","author":"Gordts","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.ijcard.2020.12.089_bb0100","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1038\/gt.2013.30","article-title":"Beneficial effects of selective HDL-raising gene transfer on survival, cardiac remodelling and cardiac function after myocardial infarction in mice","volume":"20","author":"Gordts","year":"2013","journal-title":"Gene Ther."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0105","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.ijcard.2016.04.029","article-title":"HDL mimetic peptide CER-522 treatment regresses left ventricular diastolic dysfunction in cholesterol-fed rabbits","volume":"215","author":"Merlet","year":"2016","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0110","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1038\/bjp.2008.122","article-title":"Regression of aortic valve stenosis by ApoA-I mimetic peptide infusions in rabbits","volume":"154","author":"Busseuil","year":"2008","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0115","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1161\/01.CIR.0000109213.10461.F6","article-title":"Cardiac systolic and diastolic dysfunction after a cholesterol-rich diet","volume":"109","author":"Huang","year":"2004","journal-title":"Circulation."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0120","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1002\/clc.22378","article-title":"Left ventricular diastolic dysfunction and E\/E' ratio as the strongest echocardiographic predictors of reduced exercise capacity after acute myocardial infarction","volume":"38","author":"Fontes-Carvalho","year":"2015","journal-title":"Clin. Cardiol."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0125","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1177\/0961203307087303","article-title":"E\/E\u2019 ratio is more sensitive than E\/a ratio for detection of left ventricular diastolic dysfunction in systemic lupus erythematosus","volume":"17","author":"Lee","year":"2008","journal-title":"Lupus."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0130","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1093\/eurheartj\/ehp498","article-title":"Tissue Doppler E\/E' ratio is a powerful predictor of primary cardiac events in a hypertensive population: an ASCOT substudy","volume":"31","author":"Sharp","year":"2010","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0135","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.carpath.2008.12.008","article-title":"Large animal models for diastolic dysfunction and diastolic heart failure-a review of the literature","volume":"19","author":"Dubi","year":"2010","journal-title":"Cardiovasc. Pathol."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0140","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1016\/j.cardfail.2014.09.001","article-title":"Murine models of diastolic dysfunction and heart failure with preserved ejection fraction","volume":"20","author":"Horgan","year":"2014","journal-title":"J. Card. Fail."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0145","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1111\/bph.12236","article-title":"Improvement of aortic valve stenosis by ApoA-I mimetic therapy is associated with decreased aortic root and valve remodelling in mice","volume":"169","author":"Trapeaux","year":"2013","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0150","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1194\/jlr.M071043","article-title":"Influence of route of administration and lipidation of apolipoprotein A-I peptide on pharmacokinetics and cholesterol mobilization","volume":"58","author":"Tang","year":"2017","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.ijcard.2020.12.089_bb0155","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.atherosclerosis.2012.03.006","article-title":"ApoA-1 infusion reduces arterial cholesterol and myocardial lesions in a rat model of cardiac dysfunction and insulin resistance","volume":"222","author":"Borthwick","year":"2012","journal-title":"Atherosclerosis."}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527320343370?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527320343370?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T20:53:51Z","timestamp":1759092831000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527320343370"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":31,"alternative-id":["S0167527320343370"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2020.12.089","relation":{},"ISSN":["0167-5273"],"issn-type":[{"type":"print","value":"0167-5273"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"ApoA-I mimetic does not improve left ventricular diastolic dysfunction in rabbits without aortic valve stenosis","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2020.12.089","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}