{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T05:11:16Z","timestamp":1782537076709,"version":"3.54.5"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.ijcard.2024.131879","type":"journal-article","created":{"date-parts":[[2024,2,16]],"date-time":"2024-02-16T11:40:37Z","timestamp":1708083637000},"page":"131879","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Copeptin for the differentiation of type 1 versus type 2 myocardial infarction or myocardial injury"],"prefix":"10.1016","volume":"403","author":[{"given":"Mona","family":"Kassem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Lopez","family":"Ayala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tijana","family":"Andric-Cancarevic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milos","family":"Tajsic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kris G.","family":"Vargas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitri","family":"Bendik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Kaufmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johann","family":"Wojta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurt","family":"Huber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2024.131879_bb0005","doi-asserted-by":"crossref","first-page":"e618","DOI":"10.1161\/CIR.0000000000000617","article-title":"Fourth universal definition of myocardial infarction (2018)","volume":"138","author":"Thygesen","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2024.131879_bb0010","doi-asserted-by":"crossref","first-page":"777","DOI":"10.3949\/ccjm.80a.12158","article-title":"Third universal definition of myocardial infarction: update, caveats, differential diagnoses","volume":"80","author":"Tehrani","year":"2013","journal-title":"Cleve. Clin. J. Med."},{"key":"10.1016\/j.ijcard.2024.131879_bb0015","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1016\/j.jacc.2019.02.018","article-title":"Type 2 myocardial infarction: JACC review topic of the week","volume":"73","author":"Sandoval","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2024.131879_bb0020","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1161\/CIRCULATIONAHA.112.100867","article-title":"High-sensitivity cardiac troponin in the distinction of acute myocardial infarction from acute cardiac noncoronary artery disease","volume":"126","author":"Haaf","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2024.131879_bb0025","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s11239-015-1292-5","article-title":"Circulating levels of plasminogen and oxidized phospholipids bound to plasminogen distinguish between atherothrombotic and non-atherothrombotic myocardial infarction","volume":"42","author":"DeFilippis","year":"2016","journal-title":"J. Thromb. Thrombolysis"},{"key":"10.1016\/j.ijcard.2024.131879_bb0030","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.ijcard.2016.04.045","article-title":"Chest pain, dyspnea and other symptoms in patients with type 1 and 2 myocardial infarction. A literature review","volume":"215","author":"Lippi","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.ijcard.2024.131879_bb0035","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1007\/s00392-018-1403-3","article-title":"Variations on classification of main types of myocardial infarction: a systematic review and outcome meta-analysis","volume":"108","author":"Vargas","year":"2019","journal-title":"Clin. Res. Cardiol."},{"key":"10.1016\/j.ijcard.2024.131879_bb0040","first-page":"317","article-title":"Cardiac troponin changes to distinguish type 1 and type 2 myocardial infarction and 180-day mortality risk","volume":"3","author":"Sandoval","year":"2014","journal-title":"Eur. Heart J. Acute Cardiovasc. Care"},{"key":"10.1016\/j.ijcard.2024.131879_bb0045","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1373\/clinchem.2014.236638","article-title":"Diagnosis of type 1 and type 2 myocardial infarction using a high-sensitivity cardiac troponin I assay with sex-specific 99th percentiles based on the third universal definition of myocardial infarction classification system","volume":"61","author":"Sandoval","year":"2015","journal-title":"Clin. Chem."},{"key":"10.1016\/j.ijcard.2024.131879_bb0050","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1016\/j.ajem.2018.06.073","article-title":"Differentiating type 1 and 2 acute myocardial infarctions using the N-terminal pro B-type natriuretic peptide\/cardiac troponin T ratio","volume":"36","author":"Nowak","year":"2018","journal-title":"Am. J. Emerg. Med."},{"key":"10.1016\/j.ijcard.2024.131879_bb0055","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1001\/jamacardio.2021.0669","article-title":"Cardiovascular biomarkers in the early discrimination of type 2 myocardial infarction","volume":"6","author":"Nestelberger","year":"2021","journal-title":"JAMA Cardiol."},{"key":"10.1016\/j.ijcard.2024.131879_bb0060","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1161\/CIRCULATIONAHA.120.046682","article-title":"Biomarkers enhance discrimination and prognosis of type 2 myocardial infarction","volume":"142","author":"Horiuchi","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2024.131879_bb0065","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2018-028311","article-title":"Multicentre cross-sectional observational registry to monitor the safety of early discharge after rule-out of acute myocardial infarction by copeptin and troponin: the pro-Core registry","volume":"9","author":"Giannitsis","year":"2019","journal-title":"BMJ Open"},{"key":"10.1016\/j.ijcard.2024.131879_bb0070","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1093\/eurheartj\/ehu178","article-title":"Early discharge using single cardiac troponin and copeptin testing in patients with suspected acute coronary syndrome (ACS): a randomized, controlled clinical process study","volume":"36","author":"Mockel","year":"2015","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2024.131879_bb0075","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.ijcard.2016.08.304","article-title":"Copeptin for the early rule-out of non-ST-elevation myocardial infarction","volume":"223","author":"Vargas","year":"2016","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2024.131879_bb0080","doi-asserted-by":"crossref","first-page":"3875","DOI":"10.1093\/eurheartj\/ehad447","article-title":"Accelerated -rule-out of acute myocardial infarction using prehospital copeptin and in-hospital troponin: the AROMI study","volume":"44","author":"Pedersen","year":"2023","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2024.131879_bb0085","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1016\/j.ijcard.2012.12.039","article-title":"Copeptin and cardiovascular disease: a review of a novel neurohormone","volume":"167","author":"Yalta","year":"2013","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2024.131879_bb0090","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.ijcard.2010.12.068","article-title":"Copeptin (C-terminal provasopressin): a promising marker of arrhythmogenesis in arrhythmia prone subjects?","volume":"148","author":"Yalta","year":"2011","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2024.131879_bb0095","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1373\/clinchem.2010.161265","article-title":"Combined testing of high-sensitivity troponin T and copeptin on presentation at prespecified cutoffs improves rapid rule-out of non-ST-segment elevation myocardial infarction","volume":"57","author":"Giannitsis","year":"2011","journal-title":"Clin. Chem."},{"key":"10.1016\/j.ijcard.2024.131879_bb0100","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1007\/s00392-011-0343-y","article-title":"Comparison of the temporal release pattern of copeptin with conventional biomarkers in acute myocardial infarction","volume":"100","author":"Gu","year":"2011","journal-title":"Clin. Res. Cardiol."},{"key":"10.1016\/j.ijcard.2024.131879_bb0105","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/j.jacc.2021.06.027","article-title":"A biomarker model to distinguish types of myocardial infarction and injury","volume":"78","author":"Neumann","year":"2021","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2024.131879_bb0110","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3343\/alm.2020.40.1.7","article-title":"Performance of Copeptin for early diagnosis of acute myocardial infarction in an emergency department setting","volume":"40","author":"Jeong","year":"2020","journal-title":"Ann. Lab. Med."},{"key":"10.1016\/j.ijcard.2024.131879_bb0115","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/s00392-020-01712-y","volume":"110","author":"Giannitsis","year":"2021","journal-title":"Clin. Res. Cardiol."},{"key":"10.1016\/j.ijcard.2024.131879_bb0120","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1161\/CIRCULATIONAHA.120.052982","article-title":"Novel criteria for the observe-zone of the ESC 0\/1h-hs-cTnT algorithm","volume":"144","author":"Lopez-Ayala","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2024.131879_bb0125","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/j.jacc.2019.12.065","article-title":"Early diagnosis of myocardial infarction with point-of-care high-sensitivity cardiac troponin I","volume":"75","author":"Boeddinghaus","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2024.131879_bb0130","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1161\/CIRCULATIONAHA.106.685503","article-title":"C-terminal provasopressin (copeptin) as a novel and prognostic marker in acute myocardial infarction: Leicester acute myocardial infarction peptide (LAMP) study","volume":"115","author":"Khan","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2024.131879_bb0135","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.jacc.2009.01.076","article-title":"Incremental value of copeptin for rapid rule out of acute myocardial infarction","volume":"54","author":"Reichlin","year":"2009","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2024.131879_bb0140","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.jacc.2013.04.011","article-title":"Copeptin helps in the early detection of patients with acute myocardial infarction: primary results of the CHOPIN trial (Copeptin helps in the early detection of patients with acute myocardial INfarction)","volume":"62","author":"Maisel","year":"2013","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2024.131879_bb0145","first-page":"341","article-title":"Copeptin, a stable peptide derived from the vasopressin precursor, correlates with the individual stress level","volume":"29","author":"Katan","year":"2008","journal-title":"Neuro Endocrinol. Lett."},{"key":"10.1016\/j.ijcard.2024.131879_bb0150","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.advms.2015.07.002","article-title":"Copeptin: pathophysiology and potential clinical impact","volume":"60","author":"Lukaszyk","year":"2015","journal-title":"Adv. Med. Sci."},{"key":"10.1016\/j.ijcard.2024.131879_bb0155","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.amjmed.2013.02.029","article-title":"Classification of myocardial infarction: frequency and features of type 2 myocardial infarction","volume":"126","author":"Saaby","year":"2013","journal-title":"Am. J. Med."},{"key":"10.1016\/j.ijcard.2024.131879_bb0160","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.amjcard.2009.03.003","article-title":"Frequency of elevated troponin I and diagnosis of acute myocardial infarction","volume":"104","author":"Javed","year":"2009","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ijcard.2024.131879_bb0165","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.ijcard.2008.10.021","article-title":"The impact of the 2007 ESC-ACC-AHA-WHF universal definition on the incidence and classification of acute myocardial infarction: a retrospective cohort study","volume":"139","author":"Melberg","year":"2010","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2024.131879_bb0170","doi-asserted-by":"crossref","first-page":"341","DOI":"10.2459\/JCM.0000000000000504","article-title":"Type 2 myocardial infarction: incidence, presentation, treatment and outcome in routine clinical practice","volume":"18","author":"Radovanovic","year":"2017","journal-title":"J. Cardiovasc. Med. (Hagerstown)"},{"key":"10.1016\/j.ijcard.2024.131879_bb0175","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1093\/eurheartj\/ehaa575","article-title":"2020 ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation","volume":"42","author":"Collet","year":"2021","journal-title":"Eur. Heart J."}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527324003255?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527324003255?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T21:04:45Z","timestamp":1759093485000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527324003255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":35,"alternative-id":["S0167527324003255"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2024.131879","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Copeptin for the differentiation of type 1 versus type 2 myocardial infarction or myocardial injury","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2024.131879","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"131879"}}